심근 허혈-재관류 백서 모델에서 mitogen-activated protein kinase 활성화에 대한 α-lipoic acid의 효과

김연경,박은미,최준호,윤경호,유남진,이은미,김남호,정진원,김민선,박병림,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

자료포락분석(DEA)를 이용한 보건의료의 효율성 측정

김남송,박홍섭,김은진,김설화,김정숙,김현아,김경숙,신지혜,최은정,양은진,유선미,유수진 圓光大學校 醫科學硏究所 2007 圓光醫科學 Vol.22 No.1

Inoue Balloon을 이용한 PMV의 장·단기 결과 분석

진은선,이연아,전숙,김현숙,정승묵,박상선,최락경,임달수,홍석근,황흥곤 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

관절염을 가진 대상자의 가족지지, 자가 간호 및 삶의 질과의 관계

선은경,박소연,박일지,서가은,손용숙,손인옥,용진선 가톨릭대학교 간호대학 호스피스 교육연구소 2006 호스피스논집 Vol.10 No.-

Purpose : The purpose of this study was to investigate relationships among family support, self-care, and quality of life of patients with arthritis through a survey. That will be basic data to plan nursing intervention for promoting quality of life for patients with arthritis. Method : The convenient sample of this study consisted of 120 patients with arthritis and data were collected using questionnaires during August 2006 from two OPDs of rheumatoid centers in C University hospitals. The study instruments were used to measure Self Care (So, 1992), Family Support (Kang, 1984), and Quality of Life (Ro, 1988). The data were analyzed using ANOVA, Duncan test, and Pearson correlation. Result : The mean scores were 3.56 for family support, 4.16 for self-care, and 3.19 for quality of life. The level of self-care was significantly higher in those men, having an occupation, higher income, and living with family members. The level of family support was significantly higher in those men, having an occupation, living with family members, and having a helper. The level of quality of life was significantly higher for those men, having a higher income, and shorter length of illness. Three relationships were found to be positively correlated: 1) between the levels of family support and self-care (r=.53), 2) between the levels of self-care and quality of life (r=.55), and 3) between the levels of family support and quality of life (r=.54). Conclusion: Therefore, a nursing intervention program needs to be developed to promote family support, and self-care for quality of life for patients with arthritis.

한국판 사건충격척도 수정판의 신뢰도 및 타당도 연구

은헌정,권태완,이선미,김태형,최말례,조수진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : The present study was conducted to explore the reliability and validity of the "Impact of Event Scale-RevisedKorean version" (IES-R-K). Methods : The subjects were college students who visited a college counseling center and patients who were admitted to a general hospital and two orthopedic local clinics.Those subjects who experienced catastrophic traumatic events were tested for CAPS, BDI, STAI-I, II, and MMPI-PTSD scale. Results : The range of correlations between item-total were .45 -.89. The coefficients of internal consistency were .69 -.83, of them were the Split-half reliability was .71 and the test-retest reliability was .89, all within expected ranges. Inter-corre-lations of IES-R-K, CAPS, BDI, STAI-I, II, and MMPI-PTSD scale were high. CAPS showed the highest correlation Coef-ficient. Factor analysis indicated 4 factors in IES-R ; avoidance, hyperarousal, intrusion, and sleep problem & numbness. IES-R-K can be a useful self-rating diagnostic instrument for PTSD symptoms to be a clinical concern by using 24/25 cutoff in total score. The partial PTSD cutoff score is 17/18. Conclusion : The IES-R-K was confirmed in it's reliability and validity. IES-R-K could be applied for screening of PTSD.

소아에서의 급성 파종성 뇌척수염의 임상적 고찰

조수진,박은애,유은선,김혜순,손세정,서정완,이승주,한후재 이화여자대학교 의과대학 2003 EMJ (Ewha medical journal) Vol.26 No.2

목적: 급성 파종성 뇌척수염은 감염이나 예방 접종 후 발생하는 중추 신경계의 급성 자가 면역 염증성 질환으로 탈수초를 일으킨다. 신경학적인 증상으로 발현되고 대부분 환전히 회복되지만 신경학적 후유증을 남기거나 사망 할 수도 있다. 이에 저자들은 본원에서 발생 한 14명을 분석하여 조기 진단과 치료에 도움을 주고자 하였다. 대상과 방법: 1998년 3월부터 2003년 8월까지 이대목동병원에서 급성 파종성 뇌척수염으로 진단 받은 14명의 의무기록을 후향적으로 조사하였다. 결과: 환자들의 평균 발생 연령은 5±7.8개월이였고, 특정계절이나 연도에 집중되어서 나타나지는 않았다. 선행질환은 주로 비특이적인 상기도 감염이 가장 많았고, 초기증상으로는 경련이 가장 많았다. 그 외에 의식저하나 운동장애도 있었다. 뇌척수액 검사에서 백혈구 증가증이 발견된 경우는 있었으나 단백이 증가된 경우는 없었다. 뇌 자기공명 촬영에서 T2 증강시 뇌백질과 기저핵에 고음영의 다발성 병소가 발견되었고 추적 촬영에서 대부분에서 소실되었다. 뇌파 검사가 시행되었던 경우 전반적인 서파가 가장 많았고 국소적인 극파가 나온 경우도 한 명 있었다. 환자들은 정맥 면역 글로블린과 메틸프레드니졸론으로 치료하였고 치료 시작 후 3~7일내 증상이 호전되었다. 모든 환자를 2달 이상 추적 관찰하였고 항경련제가 지속적으로 필요한 정도의 경련성 질환이 두 명, 신경아교증이 남아잇는 경우가 한 명, 외래에서 다발성 경화증이 의심되는 경우가 한 명 있었다. 결론: 급성 파종성 뇌척수염은 침범 부위에 따라서 다양한 임상 상으로 나타나며 면역 글로블린과 메틸프레드니졸론이 치료에 효과적이였다. 본 연구에서는 대상 환자수가 적어 신경학적 후유증의 위험요소는 밝힐 수는 없으나, 예후는 검사소견과 연관되어 있지는 않았고, 대부분에서 양호하여 완전히 회복되었으나, 신경학적 후유증이 남은 경우도 있었다. Objective:Acute disseminated encephalomyelitis(ADEM) is an acute demyelinating autoimmune inflammatory disease of the central nervous system which develops after infection of vaccination. It may be fatal, and produce a permanent residual static disability or fully recover. We retrospec-tively studied 14 cases to investigate the clinical findings and outcome of ADEM. Methods : 14cases of ADEM diagnosed at Ewha Womans University Mokdong Hospital from 1998 to 2003 were retrospectively reviewed. Results : The age of onset was 5years±7.8 months and no seasonal clustering was found. The time of onset of symptoms was between 3 to 30 days. The preceding events were nonspecific upper respiratory infections in 9 cases, aseptic meningitis in 4 cases, and gastroenteritis in one case..The initial symptoms were seizure, altered consciousness, hemiparesis, fever, headache, and vomiting. Brain MRI showed multifocal high signal intensity lesions on T2 weighted image mainly in the cerebral whith matter, basal ganglia and periventricular white matter. EEG was performed in some cases and showed generalized or focal slow waves and only one case showed focal spikes. Patients were treated with IV globulin and methylprednisolone and the symptoms improved within 3-7 days after treatment. All patients were followed up for more than 2 months and most of them fully recovered except two. Conclusion : ADEM presents in various clinical manifestations depending on its involvement of the brain lesions. Most cases recovered fully but in some cases, residual permanent neurologic sequelae remained.

중추성 요붕증이 동반된 랑게르한스 세포 조직구증 1예

김진호,문준성,문선중,이지은,최재원,은미정,천경아,조인호,윤지성,원규장,이경희 신덕섭,이형우 영남대학교 의과대학 2005 Yeungnam University Journal of Medicine Vol.22 No.2

Central diabetes insipidus (DI) is a syndrome characterized by thirst, polydipsia and polyuria. Langerhans cell histiocytosis is one of the etiologies of DI. Recently we experienced a central DI associated with Langerhans cell histiocytosis. The 44 years old female patient complained right hip pain polydipsia and polyuria. We carried out water deprivation test. After vasopressin injection, urine osmotic pressure was increased form 109mOsmol/Kg to 327mOsmol/Kg (300%). Brain MRI showed a thickened pituitary stalk and at hot bone CT.CT guided biopsy revealed abnormal histiocytes proliferation and abundant lymphocytes, The final diagnosis was central DI associated with systemic Langerhans cell histiocytosis invading hip bone, L-spine and pituitary stalk. Desmopressin and etoposide chemotherapy were performed to the patient.

조정변수로서 소비자의 유행관여, 상표친숙성, 부정적 정보가 의류상표확장 평가에 미치는 영향

황선진,송기은,이윤경 한국의류학회 2003 한국의류학회지 Vol.27 No.1

The purpose of this study was to investigate whether customers' fashion involvement, brand familiarity, and expertise of negative information moderate the influence of the original brand attitude on the attitude toward extended brand attitudes in the fashion market. For these purposes, four hypotheses were developed and data was collected from 480 students. Data was analyzed using SPSS methods such as factor analysis, frequency, t-test, and moderated regression analysis. The results were as follows; it was found that the original brand attitudes positively influence the extended brand attitudes. Second, the influence of the original brand attitude on the extended brand attitudes was stronger when fashion involvement was high rather than low. Third, in the case that perceived similarity between the original and the extended product classes was high, the influence of the original brand attitudes on the extended brand attitudes was stronger when brand familarity was high. Fourth, the influence of original brand attitudes on the extended brand attitudes was stronger when the perceived expertise of negative information source on the extended brand was high. Therefore, the results suggest that extending brands requires the systematic brand management considering customers' variables such as fashion involvement, brand familiarity, negative information etc. Also, it seems that brand strategy should be based on the segmentation for targeted customers' characteristics.

노인수발보장제도 도입에 따른 노인주간보호시설의 수요증가와 시설변화에 관한 연구

오은진,박혜선 한국의료복지시설학회 2006 의료·복지 건축 Vol.12 No.2

Introduction of new longterm care policy for elderly in Korea would change many aspects of elderly care service facilities. Especially elderly home care services like adult daycare centers will expand drastically after beginning of longterm care insurance. The purpose of this study is to estimate demand of adult daycare centers by comparing with the U.S and Japanese cases. Korean government is expecting that adult daycare centers will expand ten times within 4 years. This estimate is exceeding the facility demand estimate of the U.S. and Japan. The results of population study and expecting growth rate of adult daycare centers in Seoul indicate that more than 300 centers, 4 times of the number of existing centers, are in need based on Seoul elderly population in 2004. To supply these numbers of facilities in short period, more in depth study should be followed. Existing adult daycare facilities’ in Seoul were analyzed by their building and management types. Interior spaces of adult daycare centers in Korea are similar to the U.S. and Japan in space arrangements but much smaller in size. In depth study of space programming as well as overall demand survey of adult daycare centers is urgently in need for more realistic expansion of adult daycare centers.

외과적 정출술을 이용한 치관-치근 파절된 미성숙 영구치의 치험례

이은미,김태완,김현정,김영진,남순현 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

치아의 치관-치근 파절은 치아파절이 치관과 치근에 걸쳐 발생되어 법랑질,상아질 및 백악질까지 이환된 경우로 정의 되며,치수이환여부에 따라 복잡파절과 비복잡파절로 분류될 수 있다. 치관-치근 파절의 빈도는 유치열에서 2%, 영구치열에서 5%로 나타나며,보통 상악 전치부에 호발한다. 이러한 치관-치근 파절된 치아의 수복을 위해서는 생물학적 폭경이 유지되어야 한다. 이를 위하여 사용되는 방법은 골 삭제 후 치은절제술,교정적 견인,외과적 정출 후 수복하는 방법과,인위적으로 발치하여 근관치료와 수복 후 재식하는 방법 등이 있다. 이중 외과적 정출술은 치아를 발거하여 파절부를 치은 연상으로 이동시켜 재식하는 방법으로서,이는 치관부 파절편이 임상치근의 1/2 미만인 경우에 적응증이 될 수 있으며,발견하지 못한 다른 파절편을 직접 시진할 수 있고 때로는 파절선을 순측에 위치시켜 치료시 사야확보 및 접근이 용이하다는 등의 장점이 있다. 본 증례에서는 외상으로 치관 치근 파절된 미완성 치근단의 상악 중절치를 가진 환아에서 외과적 정출술 후 근관치료와 광중합복합레진을 이용한 치관수복을 시행하였으며,정기적 검진시 양호한 결과가 관찰됨을 확인할 수 있었다. Crown-root fractures occur throughout both crown and root, and are defined as fractures involving enamel, dentin and cementum. The fractures may be grouped according to pulpal involvement into complicated and uncomplicated one. Crown-root fractures often occur on maxillary anterior teeth and comprise 5% of injuries affecting the permanent dentition and 2% in the primary dentition. To restore crown-root fractured tooth, biologic width must be maintained. For maintaining biologic width, such methods as gingivectomy following osteoplasty or orthodontic extrusion or surgical extrusion are available. Surgical extrusion is a method that extracts the tooth and replants the fractured tooth supragingivally. It is indicated when the length of the crown fragment is less than half the length of the clinical root. In these cases, root canal treatment and crown restoration using light-cured composite resin were performed after surgical extrusion, In following periodic examinations, favorable outcome was observed.