http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
구강 악성 흑색종에서 PCNA 발현에 관한 면역조직화학적 연구
황경균,남윤우,이재일,이종호,심광섭,김명진 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.6
Malignant melanoma arising from the mucosa of head and neck region was rare and showed poor prognosis. Some of malignant melanoma were transformed from benign melanotic lesion. Malignant melanoma had high cellular proliferation and rapid growth. The percentage of PCNA-positive cell (labeling index) is high in many malignant tumor. So we compared the pattern of PCNA expression in the melanotic lesion. We performed the immunohistochemical study in malignant melanoma(19 cases), benign melanotic macule(24 cases) and normal mucosa(20 cases) were diagnosed in Seoul National University Dental Hospital between 1980 and 2000. Positive PCNA staining was found mainly in malignant melanoma. The mean PCNA expression in malignant melanoma, melanotic macule, normal tissue were 29.2%, 1.4%, 0%, respectively. Significant differences in PCNA expression were noted between malignant melanoma and melanotic macule(p<0.01), normal mucosa(p<0.01). These result suggested that the PCNA expression seems to be used as a diagnostic indicator for malignancy in malignant melanoma and melanotic lesion.
김윤영,김남령,이용균,최순규,이시우,정대일 東亞大學校 1993 東亞論叢 Vol.30 No.1
As a new protective group for diols, cyclic oxalates (20) (24) were synthesized by using oxalyl chloride, ethyl oxalyl chloride, diethyl oxalate and oxalic acid. In the reaction of diol with oxalyl chloride, the product was a mixture of the cyclic oxalate (20) and mono oxalated(21). When ethyl oxalyl chloride was used which pyridine as base, acyclic oxalates (22) (25) were obtained. Whereas ethyl oxalyl chloride which triethylamine instead of pyridine, cyclic oxalates (20) (24) as well as acyclic oxalates (22) (25) were obtained. Using diethyl oxalate, the amounts of cyclic oxalates (20) (24) were increased, but there were some difficulties in separations of its desired products. Oxalic acid, however, did not afford cyclic oxalates but gave formate which probably was formed by decarboxylation of hydroxyoxalyl group.
박윤균,박병수,정길수,유남재 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.A
A series of column test with a silty marine soil mixed with Jumunjin Standard Sand were performed to investigate the characteristics of settling and consolidation of non-plastic dredged soils. Column tests were carried out by using the separable column to measure the grain size distribution of consolidated layer. Column tests were performed with changing the mixing ratio of Jumunjin Standard Sand to the silty marine soil, initial water content of slurry and initial height of slurry. Height of interface of slurry was monitored during tests and grain size distribution tests were carried out after finishing tests. Influencing factors on the particle segregation, eventually to the characteristics of settling and consolidation of non-plastic soil, were analyzed on the thesis of test results. As results of column tests, the mixing ratio of sand to the silty marine soil and the initial water content of slurry were known to affect the characteristics of settling and consolidation resulted in significant particle segregation of slurry. Initial height of slurry was found not to affect seriously to particle segregation.
비·부비동 종양의 신생혈관 형성에서 COX-2 및 VEGF의 역할
도남용,박성용,조성일,윤혁수,박선홍,박영균,권대승,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1
Background and Objectives : COX-2, the inducible form of cyclooxygenase(COX), is upregulated in transformed cells and in malignant cells, which have important roles in promotion of colorectal carcinogenesis, invasiveness and angiogenesis. Vascular endothelial growth factor(VEGF) may act as endothelial cell mitogen in various cancer tissues. It will increase tumor growth and angiogenesis. Aims of this study were to asses COX-2/VEGF expression and it's clinical correlation in sinonasal tumors and to investigate the effects on angiogenesis also. Materials and Method : The study samples were obtained from surgical removal of 27 cases of inverted papilloma(IPs), 5 cases of IP with malignant transformation(IP-MT), 16 cases of Squamous cell carcinoma(SCC) in sinonasal cavity COX-2 and VEGF expressions were assessed by immunohistochemical staining. Synchronism of COX-2/VEGF expression in one tumor cell was demonstrated with double immunofluorescence technique. Results : The expression rates of COX-2 were 37% in IP, 80% in IP-MT and 100% in SCC. The positive rates of VEGF were 29 6% in IP, 100% in IP-MT and SCC. COX-2 and VEGF expressions were increased as tumor progressed, and there is a positive correlation between COX-2 &EGF expressions. All clinical features which were compared are not associated with COX-2 &EGF expressions except malignant change in IP(p=0 028). Synchronism of COX-2/VEGF expressions was noted in all positive immunostaining samples. Conclusion : These findings suggest the role of COX-2 pathway could be involved in sinonasal tumor angiogenesis, which is modulated by VEGF COX-2 may act as autocrine factor in VEGF expression. There is a potential role for selective COX-2 inhibitors in the treatment of these lesions.
PCB용 Glass/Epoxy 프리프레그의 경화중 점성거동 연구
諸葛英淳,尹南畇 論文集 1999 論文集 Vol.16 No.2
This paper dealed the studies on the viscosity behaviors of glass/epoxy prepreg for PCB during the cure process. The dynamic scan of glass/epoxy prepreg using DSC showed that the exothermic reaction started at the temperature of 118℃. The peak temperature was 169.7℃ and the total reaction enthalpy (ΔH) was 13.54I/g. The results of ion viscosity behaviors of this prepreg system using dielectrometer exhibited the lowest ioniviscosity at about 115℃, and then the ionic viscosity was gradully increased upto 150℃. This indicated that the cure reaction of this prepreg started at 115℃ and the molecular weight was increased by the accelerated thermal cross-linking reaction.
박준수,송성진,김영환,조현,임수용,윤남균,이정기,박영주 한국비파괴검사학회 2003 학술대회 논문집 Vol.- No.1
Ultrasonic testing method has been developed to evaluate adhesive layers in blast tube for the reliability of the rocket. The main objective of the present work was to find debonding and uncharged state between steel and FRP layers. We distinguish the debonding and uncharged state using the resonance method in the adhesive layers. It was found that the higher magnitude of ultrasound is reflected for the uncharged area in frequency domain, and shown good agreements with experimental results. The traditional ultrasonic pulse-echo method offers good implements for the distinction debonding area. The nondestructive testing results were compared with the micrography of destruective testing. As results, ultrasonic testing could be utilized for the evaluation of adhesive layer in the blast tube.