1919 년 남북평화회의와 단기서군벌(段祺瑞軍閥)의 대응

박준수 한국중국학회 1993 中國學報 Vol.33 No.1

Preoperative Clinical and Pathological Characteristics of pT0 Prostate Cancer in Radical Prostatectomy

박준수,정인갑,방정균,조영미,Jae Y. Ro,홍준혁,안한종,김청수 대한비뇨의학회 2010 Investigative and Clinical Urology Vol.51 No.6

Purpose: To analyze the preoperative clinical and pathological characteristics of patients with pT0 prostate cancer. Materials and Methods: We retrospectively reviewed the records of 702 patients who underwent radical prostatectomy (RP) at our institution between January 2004 and July 2008 for clinically localized prostate cancer. If there was no evidence of residual tumor in the pathological specimen of the prostate, a patient was staged as pT0. Patients with pT0 disease were compared with a control group of patients who were operated on during the same period. Results: Overall, 9 (1.3%) patients were staged as pT0 on the pathologic examination. Significant differences were observed between the pT0 group and the control patients in the biopsy Gleason score (p=0.004), the number of positive cores on biopsy (p=0.018), the tumor length of positive cores (p<0.001), and prostate volume (p=0.015). Cutoff values predictive of pT0 tumor status were defined as a biopsy Gleason score sum ≤6, 2 or fewer positive biopsy cores, tumor length on biopsy ≤2 mm, and prostate volume >30 cm3. Whereas 8 of the 9 (88.9%) pT0 patients showed all of these characteristics, only 55 of the 693 (7.9%) control patients fulfilled the criteria. The combination suggested above afforded a sensitivity of 88.8% and a specificity of 92.1% for the prediction of pT0 status. Conclusions: The frequency of pT0 prostate cancer seen on RP was 1.3%. A combination of clinicopathological features, incorporating a biopsy Gleason score, the number of positive biopsy cores, tumor length on biopsy, and prostate volume, was useful to predict pT0 stage on RP.

Goal-Pareto 기반의 NSGA 최적화 알고리즘

박준수,박순규,신요안,유명식,이원철 대한전자공학회 2007 電子工學會論文誌-SP (Signal processing) Vol.44 No.2

본 논문에서는 최적화 알고리즘의 속도를 향상시킬 수 있는 방안으로 설계자가 원하는 목적함수들의 수렴 범위를 Goal로 설정하여 최적화를 수행하는 GBNSGA(Goal-Pareto based Non-dominated Sorting Genetic Algorithm)를 제안한다. 많은 공학 문제들은 하나의 목표치를 충족하는 해를 찾는 것이 아니라 다수 목적함수들을 충족하는 해를 찾는 것이 일반적이다. 특히, 이러한 목적함수들은 서로 상충적인 관계를 갖는 경우가 대부분이기 때문에 모든 목적함수들을 만족하는 유일해를 찾는 것은 거의 불가능하다. 그 대안으로 일부 목적을 희생하며 설계에 부합되는 최적해를 찾는 파레토(Pareto) 방식의 최적화 알고리즘들에 대한 많은 연구가 진행되었다. 본 논문에서는 이러한 파레토 기반의 최적화 알고리즘들의 성능 향상을 도모하기 위하여 설계자의 목적을 파레토 할당에 반영하는 GBNSGA를 제안하고, 그 성능을 NSGA와 weighted-sum 접근 방식과의 비교를 통해 그 우수성을 검증하였다. This paper proposes a new optimization algorithm prescribed by GBNSGA(Goal-Pareto Based Non-dominated Sorting Genetic Algorithm) whose result satisfies the user's needs and goals to enhance the performance of optimization. Typically, lots of real-world engineering problems encounter simultaneous optimization subject to satisfying prescribed multiple objectives. Unfortunately, since these objectives might be mutually competitive, it is hardly to find a unique solution satisfying every objectives. Instead, many researches have been investigated in order to obtain an optimal solution with sacrificing more than one objectives. This paper introduces a novel optimization scheme named by GBNSGA obeying both goals as well as objectives as possible as it can via allocating candidated solutions on Pareto front, which enhances the performance of Pareto based optimization. The performance of the proposed GBNSGA will be compared with that of the conventional NSGA and weighted-sum approach.

Predictive Characteristics of Malignant Pheochromocytoma

박준수,송채린,박명찬,유상준,박세준,홍석준,홍범식,김청수,안한종 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.4

Purpose: The prognosis of patients with malignant pheochromocytoma is poor, but the predictive factors are not well understood. We aimed to identify the clinical characteristics predictive of malignancy after initial surgical removal in patients with pheochromocytoma. Materials and Methods: We retrospectively reviewed the records of 152 patients diagnosed with pheochromocytoma, including 5 (3.3%) with metastasis at the time of the initial surgical excision and 12 (7.9%) who developed metastasis during follow-up. To determine the factors predictive of malignancy, we compared clinical, radiographical, and urinary chemical findings between patients with benign and malignant disease. Mean follow-up was 41.5 months (range, 0.9-298 months) after surgery. Results: Malignant tumors were significantly larger than benign tumors (11.1±4.0 cm vs. 6.2±3.4 cm, p<0.001), and postoperative persistence of arterial hypertension was more frequent after removal of malignant than benign tumors (p=0.001). Among the 147 patients without metastatic disease at diagnosis, those who developed metastasis had significantly lower concentrations of urinary catecholamine metabolites per unit of tumor, including vanillylmandelic acid (1.2 vs. 3.7 mg/day/cm, p=0.049), epinephrine (4.5 vs. 168.9 mg/day/cm, p=0.008), and norepinephrine (13.1 vs. 121.8 mg/day/cm, p<0.001). The overall 5-year metastasis-free survival rate was 84.4% and was significantly higher in patients with smaller tumors (≤5.5 vs. >5.5 cm; 90.6% vs. 81.2%, p=0.025) and higher 24-hour secretion of vanillylmandelic acid (>2.1 vs. ≤2.1 mg/ day/cm; 94.9% vs. 70.9%, p=0.019). Conclusions: Large tumor size (>5.5 cm) and minimally elevated 24-hour urinary vanillylmandelic acid (≤2.1 mg/day/cm) were significantly associated with a higher probability of a malignant pheochromocytoma portending a lower metastasis-free survival and mandating more rigorous follow-up after surgery.

Prognostic and predictive value of liver volume in colorectal cancer patients with unresectable liver metastases

박준수,최두호,박희철,박원,유정일,박영석 대한방사선종양학회 2014 Radiation Oncology Journal Vol.32 No.2

To determine the prognostic and predictive value of liver volume in colorectal cancer patients with unresectable liver metastases. Materials and Methods: Sixteen patients received whole liver radiotherapy (WLRT) between January 1997 and June 2013. A total dose of 21 Gy was delivered in 7 fractions. Results: The median survival time after WLRT was 9 weeks. In univariate analysis, performance status, serum albumin and total bilirubin level, liver volume and extrahepatic metastases were associated with survival. The mean liver volume was significantly different between subgroups with and without pain relief (3,097 and 4,739 mL, respectively; p = 0.002). Conclusion: A larger liver volume is a poor prognostic factor for survival and also a negative predictive factor for response to WLRT. If patients who are referred for WLRT have large liver volume, they should be informed of the poor prognosis and should be closely observed during and after WLRT.

소아 천식에서 삶의 질에 영향을 주는 요인

박준수 대한 소아알레르기 호흡기학회 2012 Allergy Asthma & Respiratory Disease Vol.22 No.1

제트홀이 설치된 핀-휜 및 핀-휜/딤플 복합 배열을 사용한 내부유로에서의 열전달 향상

박준수,Park, Jun Su 한국교통대학교 융복합기술연구소 2015 융ㆍ복합기술연구소 논문집 Vol.5 No.1

A Pin-fin array is widely used to enhance the heat transfer in the internal cooling passage. The heat transfer distribution around the pin-fin is varied by the horseshoe vortex and flow separation. The difference of heat transfer coefficient induces the large thermal stress, which is one of the major reasons to break of hot components. So, it is required to enhance the heat transfer on the back side of pin-fin to solve the thermal stress problem. This study suggests the pin-fin with inclined jet hole and complex pin-fin/dimple array to enhance the heat transfer on the back side of pin-fin. The heat transfer coefficient is predicted by the numerical analysis, which is performed by CFX 14.0. The numerical results are obtained at Reynolds number, 10,000. The results show that the heat transfer on the back side of pin-fin is increased in both cases. Beside, the wake, which comes from dimple and jet, helps to develop the horseshoe vortex and increase the heat transfer on the next row pin-fin.

조선해양산업의 블루오션 – ICT 융합의 에센스, HILS

박준수 대한조선학회 2015 大韓造船學會誌 Vol.52 No.4

韓國의 地方自治團體에 대한 中央統制의 硏究

朴準洙 한국지방자치학회 1991 韓國地方自治學會報 Vol.3 No.1

A Competition Between Land and Mobile Networks : Price Discrimination and Access Charge Negotiation

박준수,이영호 한국경영과학회 1999 한국경영과학회 학술대회논문집 Vol.- No.2