뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향

이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP Patients who were treated with electroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain from stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from 7.7±1.7 to 4.4±2.0 with pain treatment(p<0.05). In accordance with improvement of pain scores, RS and MBI scores were also improved from 2.88±0.95 to 2.13± 1.01 and from 83.0± 16.9 to 94.7±9.5(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.

지난 2년간의 학회지 "신경정신의학" 심사 평가보고

김찬형,김세주,김도관,김성곤,박원명,송동호,박용천,이영문,오강섭,정영철,이상열,김주한,이동영,이헌정,함병주,김율리,김문두,김정진,이강욱,천근아,김재진,홍진표,홍승철 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 1종의 Sterol과 3종의 배당체 화합물의 단리·동정

이유건(Yu Geon Lee1),조정용(Jeong-Yong Cho),이현주(Hyun Joo Lee),이용현(Yong Hyun Lee),이상현(Sang-Hyun Lee),한태호(Tae-Ho Han),김월수(Wol-Soo Kim),박근형(Keun-Hyung Park),문제학(Jae-Hak Moon) 한국식품과학회 2013 한국식품과학회지 Vol.45 No.5

본 연구에서는 배의 유용성 증명을 위한 일환으로 배의 화학성분을 분자수준에서 밝히고자 하였다. 이에 배 과피 MeOH 추출물을 용매분획하여 얻은 EtOAc-산성 분획과 EtOAc-중성분획을 대상으로 Sephadex LH-20, silica gel, 그리고 ODS colmn chromatography와 HPLC를 이용하여 정제 및 단리하였다. 그 결과, EtOAc-산성 분획과 EtOAc-중성 분획으로부터 각각 2종씩의 화합물을 단리하였다. 단리된 화합물 1-4는 1H- 및 13C-NMR 분석을 통하여 각각 (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (화합물 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone(piceoside, 화합물 2), β-sitosterol (화합물 3), 그리고 β-sitosteryl 3-O-β-D-glucopyranoside (화합물 4)로 동정되었다. 단리된 3종의 배당체 화합물(화합물 1, 2, 4)들은 본 연구에 의해 배로부터 처음 동정되었으며, 화합물 3은 추황배로부터 처음 동정되었다. 본 연구결과가 배 함유 성분연구는 물론 배의 기능성 해명 연구에도 추후 중요한 기초자료로 활용되길 기대한다. We isolated and identified antioxidants from acidic and neutral ethyl acetate fractions of the peel of pear (Pyrus pyrifolia N. cv. Chuhwangbae). We isolated 4 compounds from the methanol extract, by using 3 different types of column chromatography (Sephadex LH-20, silica gel, and octadecylsilane) and preparative HPLC. We identified the isolated compounds as (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (compound 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone (picroside, compound 2), β-sitosterol (compound 3), and β-sitosteryl 3-O-β-D-glucopyranoside (compound 4) by nuclear magnetic resonance analysis. We are the first to report the identification of compounds 1, 2, and 4 from pear.

스포츠관광의 유형에 따른 스포츠관광정책의 중요성 및 활성화 방안

이재형,이근모 부산대학교 체육과학연구소 2000 體育科學硏究所 論文集 Vol.16 No.-

The purpose of this study was to provide the developmemt of sports tour with practical data and information, and to present the active plan of sports tour based on the analysis of sports tour's administrative importance to improve the quality of life and a variety of patterns which toures like in the times of glovalization, and information-intensive society with the method of self administered questionnaire-(total 496 papers)-based on common people who not only have lived in Pusan Metropolitan, but also have participated in, and seen a lot of events of sports. The results of the study are as follows: 1.The plan connected sports marketing with sports and tour is found to be presented. 2.Facilitation and investment were absolutely needed. 3.The development and advertisement of many goods are needed domestically and abroadly. 4.Mass-media and relationship of sports tour were lasted. 5.The balanced development of local areas is needed to cultivate national industry. 6.The designation of specail sports tour's area were needed to satisfy many tourers with all the desires. 7.The exchange between the developed nations and our nation is needed in sports tour. 8.The plan of sports tour and the committee of tour's development are absolutely needed. 9.The cultivation of intensive sports tour's speciallists were absolutely needed.

정보시스템 서비스의 종합적 품질평가모형에 관한 연구

이명호,윤재욱,이경근 한국경영과학회 1999 한국경영과학회지 Vol.24 No.3

Recently, information technology and information system(IS) are rapidly diffused throughout the world. In the global competitive environment, the success of IS becomes the important on e among the critical success factors(CSF) of the firm. For achieving it, the firm must continually involve itself in the quality evaluation and improvement of IS. The quality concept was changed into the customer-oriented quality one. There is no exception to the quality of IS. In the past, IS quality was determined by the IS developer or IS department offering service. Now it is evaluated by the user of IS service, and then the customer-oriented user satisfaction becomes an important issue. The purpose of this study is to develope the total quality evaluation model of IS through TQM approach First, all success factors of the domestic IS are extracted from the foreign and domestic literatures of IS success factors contained the technical and behavioral aspects. And the extracted factors are classified with evaluation levels for quality evaluation and developed into a total quality evaluation model. Finally the model usefulness is analyzed.

서울시 소재 종합사회복지관 가족복지프로그램 분석을 통한 건강가정지원센터 프로그램의 방향

이선형,김근홍 한국사회복지정책학회 2005 사회복지정책 Vol.21 No.-

본 연구는 서울시 소재 종합사회복지관의 가족복지프로그램을 분석하여 건강가정지원센터 프로그램의 방향을 논의하고자 하였다. 우선 Ⅱ장은 가족의 변화를 살펴봄으로써 전통적 가족의 관점을 벗어날 것과 함께, 가족의 구조적 변화와 기능적 변화를 놓고 볼 때 기능적 변화에 더 초점을 맞출 것을 제안했다. Ⅲ장에서는 시범 운영되고 있는 건강가정지원센터를 개괄적으로 살펴보기 위해 우리나라 가족복지서비스의 전반적인 문제점과 3개 센터의 사업내용을 살펴보았다. Ⅳ장에서는 Ⅱ장과 Ⅲ장에서 살펴 본 내용을 근거로 하여 건강가정지원센터 프로그램의 방향을 제안하기 위해 현재 대표적인 가족복지서비스 제공기관인 종합사회복지관의 가족복지프로그램을 분석하였다. 총 47개 복지관의 인터넷에 게재 되어 있는 가족복지프로그램을 대상으로 조사하여 얻은 결과를 분석한 결과 센터를 위한 다음과 같은 제안점을 얻었다. 첫째, 건강가정지원센터의 프로그램은 가족원 개별로 접근하기보다는 전체가족의 상호작용 문제를 중심으로 접근해야 한다는 점이다. 둘째, 현재까지 가족복지서비스 프로그램의 특성이 구조적 결손가족의 기능적 결선에 대한 보완에 초점을 맞추었다면, 앞으로는 기능적 결손 보완을 통한 전체가족의 접근에로의 변화를 제안하고자 한다. 셋째, 잔여적으로 선별적으로 서비스보다는 보편적 서비스 제공에 초점을 맞추되, 둘째 내용과 같은 맥락이지만 그 대상을 전체가족에게 확대해야 할 것이다. The purpose of this study is to discuss the direction of the Family-support Center program. It is discussed the change of family(esp. functional changes) in Korea and the in chapter Ⅱ. In the chapter Ⅲ, it is reviewed the present condition of the family welfare policy and service, Family-suppor Center. In the chapter Ⅳ, it is analysed that the family welfare program of 47 Community Welfare Center. The reason to analyze this center is that it is the central organization operating family welfare program. The result is as follows. First, Community Welfare Center program was focused on individual not family. So Family-support Center will be better than focusing on the family-unit. Second, now existing program is inclined to supplement family structural deficit. So Family-support Center will be better than balancing between the family structural deficit and functional deficit. Till now many study about the family were accomplished, but there is not the study about this emphasis. Finally, in the same meaning, Family-support Center will be better than focusing the universal service not the residual service.

인간 재조합 인터루긴-32 면역조절작용에 대한 유세포 분석

이광수,김영관,채정일,심정현,김은미,강형식,김수현,윤도영,명평근 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

Xenotransplantation of porcine organs has the potential to overcome the severe shortage of human tissues and organ available for human transplantation. however, it remains various hurdles for clinical xenotransplantation. In pig and mouse xenotransplantation, porcine xenograft evoke a strong cellular rejection response in immunocompetent host and grafts are destroyed within a week. This cellular immune response could involved both T cells and NK cells. A number of groups have shown that human NK cells can recognize and damage porcine endothelial cells. In addition, human T cells can respond to porcine endothelial cells through both direct and indirect mechanisms. Cellular rejection of porcine tissues requires T cells, particularly CD4^(+) cells. A new cytokine recombinant human interleukin-32α,β(IL-32α,β) has a role innate and acquired immune system. In order to investigate the role of recombinant mouse IL-18 and recombinant human IL-32α,β in xenograft rejection, we transplanted the PK(15) cells to C57BL/6 mice with or without intraperitoneal injection of recombinant mouse IL-18 or recombinant human IL-32 α,β. It was analyzed the population of NK cell, T cell and B cell in the C57BL/6 mice transplanted with PK(15) cells and recombinant mouse IL-18 or recombinant human IL-32α,β by flow cytometry analysis. As a result, lymph node and thymus of PK15/IL18, PK15/IL32α and PK15/IL32β injected group were increased to T cell activation population than normal injected groups. CD8^(+) T cells were decreased in lymph node of PK15/IL18, PK15/IL32α and PK15/IL32β injected groups. CD4^(+) T cells were increased in lymph node cell of PK15/IL32α and PK15/IL32β injected group and also, B cell population were increased in lymph node cell and spleen of PK15/IL18, PK15/IL32α and PK15/IL32β injected group. Therefore, we suggest that recombinant mouse IL-18 and recombinant human IL-32α,β suppress xenograft rejection in cellular xenotransplantation.

표면 SH파 모드의 분산특성 해석과 그 응용

이상용,박익근,윤종학,노승남,안형근 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

A new flaw detection technique using by SH angle beam method has been discussed. The SH-wave is horizontally polarized shear wave and the surface SH wave has a characteristic of traveling along near surface layer. The surface SH wave technique is valuable for the detection of fatigue cracks at fillet weld heels which cannot be detected by other ultrasonic technique such as angle beam technique and The dispersion curves of it has simple characterization. In this work, using these beneficial chraterization, quality evaluation of spot weld with ultrasonic sound intensity of SH-wave passing through nugget area of spot weld are verified experimentally.

스포츠 스폰서십 요인과 스포츠 소비자 행동에 관한 연구

이근모,김찬룡,이재형 釜山大學校 附設 體育科學硏究所 2001 體育科學硏究所 論文集 Vol.17 No.-

The purpose of this study was to analyze that sport Consumer behaviors related sports sponsorship through meta- analysis. The result of this study was concluded as follows: 1. Male, teenager affirmed factors related sports sponsorship, act an good purchase intent more than female. 2. Higher sports participation degree groups affirmed factors related sports sponsorship, act as good purchase intent. 3. Company advertisement participated sports sponsorship affirmed, company image's reliability, and act an good purchase intent more than company advertisement not participated sports sponsorship. 4. Sports sponsorship affirmed reliability, development company image, development reliability, attitude that related company image act an good purchase intent.

빅 스포츠 이벤트(월드컵) 개최와 스포츠관광 발전방안

이근모,이재형,김찬룡 釜山大學校 附設 體育科學硏究所 2001 體育科學硏究所 論文集 Vol.17 No.-

The purpose of this study is to provide ways of developing sport tourism by Investigating the trends, previous studies and theoretical background of the tourism and economic effects of big sport events, with reference to related previous literature, journals, reports, materials related to sport tourism and survey results published by Korea National Statistical Office. The Following is the conclusion suggested based on results of the study. First, participation by people of the community needs to be promoted. Especially, big sport events require systems that make possible active participation and support by people of the community. Those systems may include means of forming and collecting opinions such as open briefing, public hearings and seminars, organizations for management or consultation whose member include representative of the community, and volunteering service systems as established and strengthened as can be seen in foreign countries. Second, pre-and post evaluation system should be introduced. Like in other events big sport events have their own final and process purposes. The latter is related to the way of forming and managing sport event organizations, while the former is about ultimate results pursued by sport event. The better accomplishment of the final purpose requires understanding how sport event. The better accomplishment of the final purpose requires understanding how sport events incorporate aspects of tourism. The understanding can be made through evaluation effects of sport events before, during and after the events. Third, whether criteria of the purpose accomplishment of sport events are fulfilled can be determined through the financial analysis and economic efficiency evaluation of the events, the investigation of thoughts and attitudes by people of the community, the examination of perceptions and types of tourists and the evaluation of economic effects of those events. These processes need to be performed with consistency before, during and after sport events. Fourth, products of sport tourism need to bo developed continuously. Big sport events may attract a great attention from mass media around the world by using a variety of tourist information strategies including cultual events celebrating the ground-breaking, construction or opening of port stadiums, pam tours inviting foreign reporters and journalists which I turn lead to the production of relevant, appealing special shows, and programs showing real tastes of Korean culture. Supportive events related to Korean traditional musics, dances, martial arts, foods, pure arts and literature should be also provided to raise the atmosphere and images of sport event as well as inform this nation's history and culture. Firth, sport tourism marketing should be strengthened. Generally sports and tourism have been treated separately. But it is mow recognized that the two parts are closely correlated. such correlation between sports and tourism should be more developed. on which relevant marketing business need to be promoted.