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      • 체육교과 평가방식에 대한 소비자 의견 분석

        모창배,유인영,김정식 청주대학교 학술연구소 2004 淸大學術論集 Vol.2 No.-

        To collect customers opinion about physical education estimation system, this study targeted on 3rd grade students at academic high schools in Cheongju-city and Chungju-city in Chungcheongbuk-do. Main subjects of the study are each 4 classes in boys high school and girls high school. This paper examines the feasibility of estimation system change in the result of collecting customers opinion about estimation factors like reflection of school record and change, time factors like time obstacle and exercise ability, ability factors like influence and contents of school record, result factors like fairness of estimation, course factors like necessary and value of estimation and academic factors like private education expenses and its reduction. Based on the above result, it analyzes certification and correlation by item, sex and factor focused on every factor. Study materials are managed by SAS Package(Window Ver. 6.11). In the result of correcting customers opinion about the above estimation system, it shows as follows: First, it showed the difference by sex in change and reflection of physical education estimation system, change and influence of school record and necessary and value of estimation contents. Second, many male students supported items about exception and reflection of school record in physical education. It showed that most of students asked to change estimation system. Third, it showed time obstacle by students exercise ability in physical education estimation system. Male students have more obstacles to study other subjects than female ones. Fourth, it showed that many students asked to change estimation system not by influence of school record but by exercise ability. Fifth, it showed that many students emphasized fairness in estimation results by teachers. Sixth, in the case of male students, they asked enjoy activity and in the case of female ones, they asked physical development and health maintenance. Most students replied that physical education is necessary subject regardless of estimation. Seventh, Most students replied that physical education estimation system is not cause of increasing private education expenses directly. Eighth, students at academic high school have much correlation with estimation, time, ability, result and academic factor. On the other hand, it showed that subject factor did not much correlation with other factors.

      • KCI등재

        조직변화를 위한 대화의 특성에 대한 연구: 긍정탐구(Appreciative Inquiry)를 중심으로

        남궁은정 ( Eun Jeong Namgung ),장영철 ( Young Chul Chang ) 한국커뮤니케이션학회 2014 커뮤니케이션학연구 Vol.22 No.1

        본 연구에서는 조직변화를 이루는 과정에서 대화가 중요하다는 점을 제시하고자 하였다. 이를 위해서 최근 조직변화 관리 기법으로 부상하고 있는 긍정탐구를 기본틀로 설정하여 긍정탐구에서 대화적 특성이 어떻게 드러나는지 살펴보았다. 긍정탐구는 기존의 조직에 대한 시각에서 벗어나, 조직을 문제가 아니라 해결책이라는 긍정적인 시각을 제시했다. 또한 조직을 사회적 구성물의 하나로 보면서, 조직 구성원의 상호작용이나 상징화 등 담론 활동에 따라서 조직의 현실이 달라질 수 있다는 입장을 취하고 있다. 하지만 그동안 긍정탐구에서 긍정성이 크게 부각된 반면 사회 구성의 측면은 다뤄지지 못한 경향이 있다. 이 연구는 대화의 관점에서 긍정탐구를 살펴보면서, 긍정탐구가 조직변화를 가능하게 했던 조건이 무엇인지 알아보고자 하였다. 이를 통해 긍정탐구에 대한 관점을 확장하고, 이것이 실행의 측면에 어떻게 적용될 수 있는지에 대해서 논하였다. Dialogue plays an important role in creating the conditions for organizational changes. Based on the previous works on dialogue, this study focuses on the dialogue associated with change process. To deal with it, this study employed Appreciative Inquiry(AI) as a mean of managing collective dialogue. In AI, organization is a solution itself, not a problem to be solved. Also it holds that discursive behaviors including interactions and symbolizations of organization members can create and change the reality of an organization. A body of previous researches on AI, however, have more focused on positivity and less on aspects of social construction. This study explores that how AI can lead remarkable changes in a lot of organizations. In this study, the meaning of dialogue in AI is discussed and implications for research and practice are given.

      • KCI등재

        정신분열병에 대한 리스페리돈의 효과 및 안정성

        이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

        연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

      • Clinicopathological study on metastatic skin cancer

        ( Chang Il Kwon ),( Seo Mi Gon Jeong ),( Young Bin Shin ),( Yun Sun Moon ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

        Background: Various primary tumors can cause metastatic skin cancer. Metastatic skin lesion should be distinguished from other skin lesion. Objectives: We studied patients with metastatic skin cancer to find out average age, gender distribution, frequency of primary tumor, time interval between manifestation and primary cancer, and their clinical appearance, location and other metastatic sites. Methods: We reviewed the medical records, clinical photographs and histopathologic records of patients who had been diagnosed with metastatic skin cancer. Results: In the comparison according to clinical records, the mean age at the time of diagnosis was 60.6 years. The ratio of men to women was 1.05:1. The most frequent primary tumors were breast cancer (22.0%), lung cancer (17.0%), head and neck cancer (17%), melanoma (17.0%), gastrointestinal cancer (11%), urologic cancer (11%), and gynecologic cancer (6%). Metastatic skin cancers usually presented as discrete, painless, hard nodules, with sudden onset (88%). Conclusion: Based on the results of this study, it is believed that it is important to recognize the metastatic lesion between various skin lesion such as infections and granulomatous changes of other cause due to drugs and reactive changes.

      • The clinical manifestations of stasis dermatitis and analysis of association with other vascular diseases

        ( Jeong Won Jo ),( Chang Il Kwon ),( Young Bin Shin ),( Yun Sun Moon ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

        Background: Stasis dermatitis is a common dermatologic disorder. It is caused by venous hypertension results from venous backward flow. However, research on the association with specific vascular disease is insufficient. Objectives: This study was intended to investigate in clinical manifestations of stasis dermatitis and analysis of association with other vascular diseases in our hospital outpatients. Methods: In this study, we investigated 37 patients with a diagnosis of stasis dermatitis in our hospital from 2014 to 2019. We reviewed clinical manifestations and relation with other vascular disease. Results: In total 37 cases, 20 (54.1%) patients were female and 17 (45.9%) patients were male. Twelve two (59.5%) patients were presented as erythema, followed by 14 (37.8%) as purpuric lesions and 11 (29.7%) as brownish changes. There were 4 (10.8%) patients showed crust, 3 (8.1%) as edema, 2 (5.4%) as scale, 2 (5.4%) as ulcer. For symptoms, 15 (40.5%) patients complained itching, 4 (10.8%) as tenderness, 3 (8.1%) as pain, 1 (2.7%). In relation with other vascular disease, 16 (43.2%) patients represented with vein related disease such as deep vein thrombosis, varicose vein and thrombophlebitis. However, there was no arterial disease such as arteriosclerosis obliterans. Conclusion: The result shows clinical manifestations of stasis dermatitis and association with other specific vascular diseases. By understanding these findings, it is expected that better treatment outcome will be obtained.

      • KCI등재

        한국인 직무 스트레스 측정도구의 개발 및 표준화

        장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

      • SCIESCOPUSKCI등재

        APPLICATION OF TRAVELING SALESMAN PROBLEM(TSP) FOR DECISION OF OPTIMAL PRODUCTION SEQUENCE

        Chang, Kun Soo,Yeo, Yeong Koo,Chang, Jin Yang,Kim, Kil Su,Jeong, Eun Young,Oh, Sea Cheon 한국화학공학회 1997 Korean Journal of Chemical Engineering Vol.14 No.5

        In the present study a reliable and structural decision system for production sequence of polymeric products is developed. Minimization of the amount of off-specs are the main objective in the decision of production sequence to maximize profit. Off-specs are generated when the production sequence of polymeric products is changed. The amount of off-specs depends on changes of product grades. In the present study we applied the traveling salesman problem (TSP) to achieve optimal decision of production sequence. To solve the optimal decision problem formulated by TSP, we employed three different approaches such as Branch and Bound (B&B) method. Dynamic Programming (DP) method and Hopfield Neural Network (HNN) method. Production sequences computed based on the actual plant off-spec data were compared with the sequences employed in the actual plant operation. From the comparison the decision method proposed in the present study showed increased profits and reduced off-specs.

      • KCI등재
      • 대장암종에서 암관련 유전자들의 Promoter Methylation과 암종 발생 및 진행과의 관게에 대한 연구

        정동준,이정은,민영기,조성우,백무준,양승하,김의한,김창진 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

        The colorectal corcinoma is one of the most common malignant tumor in Korea and its carcinogenic mechanism has not been elucidated exactly yet. So far, the most common carcinogenic mechanism has been known to be multiple genetic changes. But, the CpG island hypermethylation has been revealed to be one of the most important carcinogenic mechanism second to the genetic changes. The epigenetic changes characteristically imprint and transfer to the next generation without changes of nucleotide sequences. When the CpG island of promoter or 5'- exon 1 of a specific gene is methylated by DNA methyltrasferases (DNMTs), the gene expression is inhibited. Carcinogenic mechansisms by promoter methylation has been well known, but the progression of the cancer has not been elucidated yet. The molecular researches on the carcinogenic mechanisms largely depended on the tumor tissue containing various components of cell, due to difficulties in harvesting pure homogeneous tumor cells. Promoter methylatonof the cancer related genes as APc, hMLH2, p16, DAP-K and MGMT in 50 cases of sporadic colorectal carcinoma was studied. The pure normal colorectal epithelial cells, and cancer cells from superficial and deep invasive portion were harvested respectively by laser captured microdissection(LCM), and DNA was extracted from them. The promoter methylation was studied by methylation specific poymerase reaction (MSP) after bisulfite modification of the DNA and the expression of the genes by immunohistochemistry. The results suggests that promoter methylation of the cancer related genes are closely related with the colorectal carcinogenesis and it occurrs from early phase of carcinogenesis, progressing constantly to the late stage. And the promoter methylation of normal epithelial cells increased by age. The p15, known to be the genes related to hematologic malignancy, was closely related to the colorectal carcinoma as well.

      • 개 이자의 Somatostatin 양성세포의 발달에 관한 면역조직화학적 연구

        장인엽,윤상필,정윤영,김종중,문정석,한길현,김영택,안계훈,선희매 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

        Cells immnunoreactive for somatostatin(SOM) and glucagon(GLU) were investigated in postnatal day 0, 7, 14, 28, 90, 180 and adult canine pancreas using light microscopic immunohistochemistry. Pancreatic SOM-immunoreactive cells were found in pancreatic acini, pancreatic duct, and pancreatic islet gradually. Pancreatic SOM-immunoreactive cells were more located in pancreatic parenchyme than pancreatic islet throughout pancreas by postnatal day 28. But there was change by the postnatal 3 months : pancreatic SOM-immunoreactive cells were more located in pancreatic islet than acini and duct. It is suggested that the number of the SOM-immunoreactive cells may not increase with age apparently. A small number of SOM-immunoreactive cells that showed GLU-immunoreactivity were also observed in canine pancreatic islet. The physiologic consequences of these changes remain to be determined. These results sugegest that SOM in the developing pancreas may relate to the secretion of pancreatic hormones.

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