국소약물송달제제가 성인형 치주염의 치료에 미치는 효과

박지원,권영혁,이만섭,박준봉,허익,Park, Ji-Won,Kwon, Young-Hyuk,Lee, Man-Sup,Park, Joon-Bong,Herr, Yeek 대한치주과학회 1999 Journal of Periodontal & Implant Science Vol.29 No.2

The present study was performed to assess and compare the clinical and microbiological effects following local application of 2% minocycline gel or 0.1% chlorhexidine subgingival irrigation to augment scaling and root planing in patients with moderate to advanced chronic adult periodontitis. 32 healthy patients with moderate to advanced chronic adult periodontitis were enrolled in the study. In each patient, the quadrants that had 2 or more teeth with $5{\sim}8mm$ probing pocket depth and radiographic evidence of alveolar bone loss were selected and divided into test side and control side according to the split-mouth design. All patients received standardized oral hygiene instructions at the beginning of the study and all remaining teeth received scaling and root planing until 0 week. The 2% minocycline gel was applied to periodontal pocket at 0, 1, 2, 3 week in the test side. The 0.1% chlorhexidine solution and the normal saline were irrigated subgingivally for about 30 seconds in the positive control side and negative control side respectively. The clinical and microbiological analysis carried out at 0, 4, 8, and 12 weeks . The results of this study were as follows; 1. In saline irrigation group, there was no adjunctive effects in probing pocket depth reduction, sulcular bleeding index and no significant changes in relative proportions of subgingival bacteria. 2. The chlorhexidine irrigation as an adjunct to scaling and root planing results in reduction in the plaque index and sulcular bleeding index, but there was not statistically significant. The relative proportion of spirochetes was significantly reduced, but the proportion of motile rods was no significant reduction. 3. The minocycline gel delivered subgingivally as an adjunct to scaling and root planing provide significant benefit in reducing probing depths and sulcular bleeding index compared to saline and chlorhexidine irrigation groups. 4. The relative proportions of spirochetes and motile rods were significantly reduced and the proportions of cocci and non-motile bacteria were correspondingly increased in the minocycline gel group. In conclusion, minocycline gel delivered subgingivally as an adjunct to scaling and root planing induces clinical and microbial responses more favorable for periodontal health than saline and chlorhexidine subgingival irrigation.

촉각 자극과 두점식별 자극에 따른 뇌활성도 분석: fMRI 사례 연구

박지원,김중선,Park, Ji-Won,Kim, Chung-Sun 대한물리치료학회 2010 대한물리치료학회지 Vol.22 No.4

Purpose: Sensory input is very important for proper performance of human. Two-point discrimination is the most widely used tactile sensory test. The purpose of this study was to find the changes in cortical activation patterns between tactile stimulation and two-point discrimination. Methods: Two healthy subjects participated in our study. fMRI scanning was done during 4 repeated blocks of tactile stimulation and two point discrimination of the right index finger tip. In one block, stimuli were repeated 10 times every three seconds. To determine the changes of cortical neurons during sensory input, intensity index was analyzed. Results: When tactile stimulation of the right index finger tip was completed, only contralateral primary somatosensory area was activated. In contrast, during two-point discrimination, both the primary somatosensory area and ipsilateral supplementary sensory area were activated. Conclusion: During two point discrimination, both primary somatosensory area and ipsilateral supplementary sensory area were activated. Therefore, two-point discrimination is required more complex and conscious activity than tactile stimulation.

광학R&D산실 - 초정밀가공 방산기술 국산화로 도약의 기지개 '활짝', 한국전광(주) 부설연구소

박지원,Park, Ji-Won 한국광학기기산업협회 2010 光學世界 Vol.126 No.-

한국전광(주)(대표.채진석, www.keocvi.com)는 코팅전문업체로서 국내보다는 미국, 일본, 독일 등 세계에 먼저 이름을 알리며 고출력레이저광학소자의 가공 및 코팅에서만큼은 이미 세계 최고 대열에 들어섰다고 자부한다. 최근에는 방산, 항공우주, 반도체, 의료기기 등 전방위에 들어가는 고부가가치 광학소자 및 시스템 분야로 사업 영역을 확장시키며 광학부품업체에서 토털솔루션 제작업체로 변신을 추구하고 있는 가운데 부설연구소의 김기호 연구소장을 만나 최근의 연구개발 현황을 들어보았다.

운동학습에 의한 왼쪽 하전두영역의 분할비등방성의 변화

박지원,남기석,Park, Ji-Won,Nam, Ki-Seok 대한물리치료학회 2010 대한물리치료학회지 Vol.22 No.5

Purpose: This study was to delineate the structural change of neural pathway after sequential motor learning using diffusion tensor imaging (DTI). Methods: The participants were 16 healthy subjects, which were divided by training (n=8) and control (n=8) group. The task for the training was the Serial Reaction Time Task (SRTT) which was designed by Superlab program. When the 'asterisk' shows up in the 4 partition spaces on the monitor, the subject presses the correct response button as soon as possible. The training group participated in the training program of motor learning with SRTT composed of 24 digits pattern in one hour per daily through 10 days during 2 weeks. Results: In the behavioral results the training group showed significant changes in the increase of response number and the reduction of response time than those of the control group. There was significant difference in the left inferior frontal area in the fractional anisotropy (FA) map of the training group in DTI analysis. Conclusion: Motor sequential learning as like SRTT may be needed to the learning of language and visuospatial processing and may be induced for the experience-dependent structural plasticity during short period.

의료기관의 교육이수점수제도 도입 및 인사고과 반영사례

박지원,Park, Ji-Won 대한병원협회 1997 대한병원협회지 Vol.26 No.5

일 지역 취약가구 독거노인의 건강상태에 따른 가정지원과 도움요구

박지원,김용순,김기숙,Park, Ji-Won,Kim, Yong-Soon,Kim, Ki-Sook 한국가정간호학회 2009 가정간호학회지 Vol.16 No.2

Purpose: To identify the health condition, home care support, support requirement of poor and elderly people living alone. Method: Data was collected through self-administered questionnaires and analyzed by descriptive statistics, t-test, ANOVA and correlation. Survey involved 269 conveniently selected who have a social support in H city. Result: Perceived health condition of subjects was bad to moderate (mean score: 2.22). There were significant home care support differences according to gender, religion, education level and dwelling pattern. Support requirement was influences only by the dwelling pattern. Perceived health condition showed a positive correlation with home care support of friends and neighbors, and a negative correlation with support requirement (medical, material, economic emotional support). Conclusion: These findings are expected to make a positive contribution to create an ideal intervention for public visiting nurses and social workers to improve the quality of life in poor and elderly people who live alone.

계단 보행 시 불안정성 신발 착용에 따른 슬관절 부하에 대한 연구

박지원,김윤진,Park, Ji-Won,Kim, Yun-Jin 대한물리치료학회 2014 대한물리치료학회지 Vol.26 No.2

Purpose: The purpose of this study is to compare kinematics and kinetics on the knee joint between stair gait with unstable shoes and barefoot in healthy adult women. Methods: Seventeen healthy adult women were recruited for this study. The subjects performed stair ascent and descent with unstable shoes and barefoot. The experiment was repeated three times for each stair gait with unstable shoes and barefoot. Measurement and analysis of the movements of the knee joint were performed using a three-dimensional analysis system. Results: Statistically significant differences in the knee muscle force of semimembranosus, biceps femoris-long head, biceps femoris-short head and sartorius, patellar ligament, medial gastrocnemius, and lateral gastrocnemius were observed between unstable shoes and barefoot gait during stair ascent. Statistically significant differences in the knee muscle force of sartorius, rectus femoris, medial gastrocnemius, and lateral gastrocnemius were observed between unstable shoes and barefoot gait during stair descent. Statistically significant differences in the knee flexor moment of semitendinosus, biceps femoris-long head, biceps femoris-short head, sartorius, rectus femoris, vastus intermedialis, medial gastrocnemius, and lateral gastrocnemius were observed between unstable shoes and barefoot gait during stair ascent. Conclusion: Therefore, wearing unstable shoes during stair gait in daily life is considered to influence knee joint kinematics and kinetics due to the unstable shoes, and thus suggest the possibility that reducing the risks of pain, and knee osteoarthritis, stabilizing the knee joint caused by changes in the loading of the knee joint.

가정간호교육생의 보완요법에 대한 태도와 인지정도 조사 연구

박지원,임난영,Park, Jee-Won,Lim, Nan-Young 한국가정간호학회 2002 가정간호학회지 Vol.9 No.2

Purpose: Home health nurses could affect patients' choice of alternative therapy. This study was carried out to investigate home health nurses' attitudes and cognition toward alternative therapy. Method: The subjects were 92 nurses who preparing the home health nurses at 2 university in Seoul and Suwon. Using the questionnaire. we measured the subjects' attitudes and cognition toward alternative therapy. Result: The mean score of attitudes about application was 3.14. and the score of attitudes about therapeutic effect was 2.57. The score of attitudes about therapeutic effect were significantly positive correlation to the score of cognition about alternative therapy. The attitudes about therapeutic effect were different significantly according to number of working years. But they commonly wanted to apply the soojichim. aroma-therapy. massage. danjon breathing. music therapy. plant therapy. and foot reflexology to their home health care subjects. Conclusion: Alternative therapies became a popular source of health care in Korea. This study showed pre-home health nurses had positive attitudes toward alternative therapies and they had wide variations of knowledge in how to use each therapy. But they acknowledge the value of alternative therapies as useful nursing interventions. so we all nurses should pay attention to develope the nursing intervention using alternative therapy.

자살시도자들에서 충동성과 자살시도의 의학적 치명도와의 관계

박지원,서경훈,손경훈,한재현,전영주,정유진,이원준,성수정,한창환,조규종,황재연,Park, Ji Won,Suh, Kyung Hoon,Son, Kyung Hoon,Han, Jae Hyun,Jeon, Yeong Ju,Jung, Yu Jin,Lee, Won Joon,Seong, Su Jeong,Han, Chang Hwan,Cho, Gyu Chong,Hwang, J 대한생물정신의학회 2018 생물정신의학 Vol.25 No.4

Objectives Although impulsivity has long been thought as an important factor influencing suicidal behaviors, it is unknown whether impulsivity increases the risk of dying from suicidal behaviors and what specific component among constructs of impulsivity contributes to the risk of dying among suicide attempters. Methods To elucidate the association between impulsivity and medical lethality of suicide attempt among suicide attempters, we consecutively recruited 46 suicide attempters who visited an emergency room of a general hospital located in a metropolitan area, Seoul, Republic of Korea, due to suicide attempts and consented to participate in this study. Then we assessed medical lethality with the Beck Lethality Scale (LS) and impulsivity with the Korean version of the Barratt Impulsiveness Scale-11-Revised (BIS). Demographic variables were obtained from medical records and structured social work reports for suicide attempters. Results Although total scores of the BIS did not correlate with LS scores, only the scores of self-control, that is one of the Barrett's six theoretical constructs of impulsivity in which the higher score indicates less self-control and more impulsivity, had a significant positive correlation with scores of LS (p = 0.003). The association remained significant after adjusting for variables known to affect suicide lethality such as job status, recent alcohol consumption, diagnosis of depressive disorders, and having a plan for suicide (${\beta}=0.429$, p = 0.009). Conclusions Not impulsivity in general, but poor self-control, in particular, predicts lethal suicidal behaviors among suicide attempters. The degree of self-control should be evaluated when assessing patients with elevated suicide risk, and proper measures should be installed to prevent possible future lethal suicide attempts.

볶음땅콩가루, 새싹 땅콩가루를 첨가한 쌀파이의 품질 특성

박지원,김민영,김미옥,이혜림,이진주,김수경,정헌상,이연리,Park, Ji Won,Kim, Min Young,Kim, Mi Ok,Lee, Hye Rim,Lee, Jin Ju,Kim, Su Kyung,Jeong, Heon Sang,Lee, Youn Ri 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.5

The purpose of this study is to make rice pie, a bakery item, to enhance use of rice flour and analyze quality characteristics of rice pie by adding roasted peanut flour and peanut sprout flour. Water content of rice pie adding roasted peanut flour or peanut sprout flour is lower than that of wheat pie. The pH of rice pie is lower than that of wheat pie, and pH becomes higher when roasted peanut flour or peanut sprout flour is added. Density of dough is lower in rice pie than in wheat pie, and when roasted peanut flour or peanut sprout flour is added, rice pie reveals higher density. Loss rate is higher in rice pie than in wheat pie, and when roasted peanut flour or peanut sprout flour is added, rice pie reveals lower loss rate. When roasted peanut flour or peanut sprout flour is added to rice pie, its brightness (L) and yellowness (b) decrease, while redness (a) increases. Hardness is higher in pie made of rice powder than in wheat pie, and when roasted peanut flour or peanut sprout flour is added, hardness becomes lower. Regarding composition of fatty acids in rice pie, saturated fatty acids observed are myristic acids, palmitic acids, and stearic acids. Monounsaturated fatty acids found are mainly oleic acids. Polyunsaturated fatty acids detected are linoleic acids, and are found more in pie made of rice powder, than in wheat pie.