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허익,권영혁,이만섭 慶熙大學校 齒科大學 1989 慶熙齒大論文集 Vol.11 No.-
The thirty-three maxillary first molars, which were extracted because of the severe periodontal disease, were cross sectioned every 1.5 millimeter from the Cementoenamel junction to the apex, and each section was photographed, projected and measured with a calibrated Digital Curvi-Meter (Corn Curve-8, Japan). The root surface area (RSA), percentage of' the RSA, and the linear variation of the RSA were calibrated for each 1.5mm section: The location of root separation was determined and the length of roots were calculated separately. The results were as follows: 1. The mean length of the roots were 11.52mm for the palatal root, 1 1.28mm for the mesiobuccal root, and 10.68mm for the disobuccal root. The distobuccal root was shortest among the three roots. 2. The mean distance from the Cementoenamel junction to the point at which the roots separate from the root trunk was 4.57mm for the mesiobuccal root and 4.66mm for the distobuccal root. The mesiobuccal root separation was more coronal than the distobuccal root separation but the differences were not significant. 3. The mean root surface area was 88.44mm2 for the mesiobuccal root, 80.14mm2 for the palatal root, and 58.87mm2 for the disobuccal root. The mean mesiobuccal root surface area was wider than the mean palatal root surface area (p < 0.05). 4. The mean surface area of the root trunk was 155.67mm2 and averaged 40.63% of the total root surface area. It was wider than the mean surface area of each roots. 5. The coronal one-half of the root length accounted for approximately 60% of the total root surface area.
치근이개부 수평결손시 조직재생에 관여하는 전구세포의 면역세포화학적 연구
허익,권영혁,Herr, Yeek,Kwon, Young-Hyuk 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.2
The origin of fibroblasts, their proliferative activity and roles in the early stages of periodontal regeneration were investigated in order to better understand the periodontal healing process in furcation defects of the beagle dog after guided tissue regeneration. Newly divided cells were identified and quantitated by immunolocalization of bromodeoxyuridine (BrdU) injected 1 hour prior to sacrificing the animals. The results were as follows :1. During periodontal healing in horizontal furcation defect, three different stages, namely the granulation tissue, connective tissue, and bone formation stages, were identified on the basis of major types of cells and tissue. 2. In the early stages of periodontal regeneration, both the remaining periodontal ligament and alveolar bone compartment were the major sources. 3. The majority of BrdU-labeled fibroblasts were located at the following areas ; 1) the coronal zone of the defect in case of the connective tissue fanned on the root surface. 2) the area within an 400 ${\mu}m$ distance from the remaining bone level in case of the periodontal ligament. 3) the area within an 100 ${\mu}m$ distance from the bone surface in case of areas of active bone formation.4. The highly proliferative fibroblasts adjacent to bone surface played a major role in the formation of osteoblast precursor cells, whereas both paravascular and endosteal cells played a minor role in new bone formation, In conclusion, it was suggested that the fibroblasts in the remaining periodontal ligament and bone will play a major role in periodontal regeneration, whereas both paravascular and endosteal cells will play a minor role in new bone formation.