A 37Ch Visible Adaptive Optics System for Wavefront Compensation

이준호,Byung Tae Choi,Eung Cheol Kang,Hae Seog Kho,Ho Jung Cheon,Jae Il Lee,Joon Won Kim,Kyung Muk Lee,Sung Jin Kim,Young Cheol Lee,Young Il Cho 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.1

A visible adaptive system was developed to compensate for phase distortions of a visible (He-Ne) laser. The visible adaptive optics (AO) system consists of 5 subsystems: a Shack-Hartmann wavefront sensor, a deformable membrane mirror of 15 mm with 37 actuators, a high-speed tip/tilt mirror of 20 mm, a position sensor and a control & display unit. The lab-developed Shack-Hartmann sensor was experimentally shown to have a measurement accuracy of better than RMS /50 at 0.6328 μm over the maximum phase distortion that the deformable mirror could generate, i.e., approximately /4. The adaptive optics system operated the deformable mirror at 10 Hz and the tip/tilt mirror at 30 Hz, which were, respectively, closed by the Shack-Hartmann sensor and the position sensor. The closed adaptive optics system was demonstrated to compensate for time-varying wavefront aberrations of PV (Peak-to-Valley) 1.2 μm with a time frequency of 1.4 Hz. The residual RMS wavefront error was shown to be smaller than 0.014 μm, i.e., /45 at 0.6328 μm.

Experimental Evaluation of Q-Parameterization Control for the Imbalance Compensation of Magnetic Bearing Syatem

이준호,김현기,이정석,이기서,Lee, Jun-Ho,Kim, Hyeon-Gi,Lee, Jeong-Seok,Lee, Gi-Seo 대한전기학회 1999 전기학회논문지A Vol.48 No.3

This paper utilizes the method of Q-parameterization control to design a controller which solves the problem of imbalance in magnetic bearing systems. There are two methods to solve this problem using feedback controal. The first method is to compensate for the imbalance forces by generating opposing forces on the bearing surface (imbalance compensation). The second method is to make the rotor rotate around its axis of inertia (automatic balancing);in this case no imbalance forces will be generated. In this paper we deal with only imbalance compensation. The free parameter of the Q-parameterization controller is chosen such that these goals are achieved. After the introduction of a model of the magnetic bearing system, we explain the Q-parameterization controller design of the magnetic bearing system with emphasis on the rejection of sinusoidal disturbance for imbalance compensation design. The design objectives are formulated as a linear equations in the controller free paramete Q. Finally, simulation and experimental results are presented and showed the robustness and effectiveness of the proposed controllers.

정맥용 면역글로불린 투여 후 발생한 무균성 수막염 3례

이준호,송은경,이진아,김남희,김동호,박기원,최은화,이환종,Lee, Joon Ho,Song, Eun Kyoung,Lee, Jin A,Kim, Nam Hee,Kim, Dong Ho,Park, Ki Won,Choi, Eun Hwa,Lee, Hoan Jong 대한소아감염학회 2005 Pediatric Infection and Vaccine Vol.12 No.2

IVIG 투여에 의해 무균성 수막염은 그 기전이 밝혀지지 않았으나 IVIG 투여와 관련된 신경학적 부작용 중 가장 중한 합병증의 하나이다. 저자들은 서울대학교 어린이병원에서 2003년부터 2004년까지 3명의 환아에서 확인된 IVIG 투여와 관련된 무균성 수막염 4례를 경험하여 보고하였다. 3명의 환아는 ITP, 가와사키병, 중증 근무력증으로 기저질환은 각각 상이하였으나 기저질환에 대한 치료를 위해 모두 고용량의 IVIG를 투여받았으며, IVIG를 투여받은 후 1~2일 이내에 심한 두통과 뇌막자극 징후를 보였다. 척수액 소견상 백혈구 수는 $100/{\mu}L$ 미만에서부터 $1,000/{\mu}L$ 이상까지 다양하였으나 주로 다핵구로 구성된 척수액 백혈구 분포를 보였고(66~98%), 세균 배양검사와 장바이러스 배양과 PCR 검사에서 음성 결과를 보였다. 3명의 환아 모두 수막염 발생 2일 후까지는 증상이 호전되었으며, 후유증 및 장애가 없었다. Intravenous immune globulin(IVIG) is widely used for immune thrombocytopenic purpura (ITP), Kawasaki disease and other autoimmune neuromuscular disease. Aseptic meningitis was one of the most serious neurologic complications reported following the use of IVIG. We experienced 4 episodes of aseptic meningitis associated with IVIG usage in 3 patients from 2003 to 2004. Underlying disease of each patients was ITP, Kawasaki disease and myathenia gravis and all of them received high dose IVIG treatment for their underlying disease. Within a days, they started to complain severe headache and diagnosed meningitis by cerebrospinal fluid analysis. Cerebrospinal fluid leukocyte counts varied from 92 to over a thound per microliter with dominance of polymorphonuclear leukocytes. Microbiologic studies revealed no organisms. All of them were free from headache within 2 days and did not suffer any neurological sequelae.

2001년 경상북도에서 발생한 콜레라 유행에 관한 역학조사

이준호,이관,김준철,이상원,고운영,양병국,이종구,김문식,임현술,Lee, Jun-Ho,Lee, Kwan,Kim, Jun-Chul,Lee, Sang-Won,Go, Un-Yeong,Yang, Byung-Kuk,Lee, Jong-Koo,Kim, Moon-Sik,Lim, Hyun-Sul 대한예방의학회 2002 예방의학회지 Vol.35 No.4

Objectives : This study was carried out to investigate the cause, magnitude and transmission route of the cholera outbreak in 2001 Methods : The study population were those persons who ingested foods at the restaurant, were confirmed as cholera patients, had symptoms of diarrhea and sewed as workers at the restaurant. A questionnaire survey and microbiological examinations on the microbes isolated from rectal swabs were conducted. Of the cases, 316 food histories were surveyed by an analysis of the restaurant menu. Results : There were 139 confirmed cases of cholera reported in Korea in 2001. Of these, 104 were related to the restaurant. By region, Gyeongsangbuk-do had the highest incidence with 91 cases. Of these 91 cases, 74 had ingested foods at the restaurant, 2 were employees and 3 were secondary infection cases within the families. The results of the odds ratio analysis of the 316 persons having ingested foods at the restaurant were as follows: sandwiches 5.07 (95% CI, 1.85-14.59), soybean curd 2.45 (95% CI, 1.09-5.56), noodles 2.34 (95% CI, 1.24-4.42), steamed squid 2.01 (95% CI, 1.17-3.47) and vinegared rice 1.82 (95%, CI, 1.08-3.09). It was certain the restaurant in question was the cause of the 2001 outbreak. Conclusions : We suspected that more than one restaurant employee contaminated foods served at the restaurant. In addition, eating raw fishes purchased at the Pohang Fisheries infected the employees of the restaurant. There is a possibility that these raw fishes were themselves contaminated by cholera bacilli in the sea.

지표면 침적 방사성핵종에 대한 NaI(Tl), LaBr₃(Ce) 및 CeBr₃ 검출기의 MDA 비교 평가

이준호,김봉기,이동명,변종인,Lee, Jun-Ho,Kim, Bong-Gi,Lee, Dong Myung,Byun, Jong-In 한국방사성폐기물학회 2019 방사성폐기물학회지 Vol.17 No.3

본 연구에서는 원자력 사고 또는 방사선 비상 시 지표면에 침적될 수 있는 감마선방출 핵종의 방사능을 신속하게 평가하기 위해 이용될 수 있는 NaI(Tl), $LaBr_3$(Ce) 및 $CeBr_3$ 섬광검출기의 성능을 비교 평가하였다. 검출성능은 최소검출가능방사능(MDA, Minimum Detectable Activity)을 통해 평가하였으며, 각 검출기의 지표면 침적 감마선방출 핵종에 대한 검출효율은 수학적 모델링과 점선원을 이용하여 반실험적으로 산출하였다. MDA 평가를 위한 백그라운드 감마선에너지스펙트럼은 비교적 넓고 평탄한 초지에서 측정되었으며, 원자력 사고 시 방출될 수 있는 주요 핵종에 대한 각 검출기의 MDA를 산출하였다. 그 결과 일반 환경방사능 준위에서 지표면 침적 감마핵종에 대한 각 검출기의 MDA 크기는 대체로"NaI(Tl)> $LaBr_3$(Ce)> $CeBr_3$"로 평가되었으며, 백그라운드 준위가 유사한 에너지 영역에서는 분해능이 가장 우수한 $LaBr_3$(Ce)에서 최소 값을 보였다. 이는 관심 핵종의 감마선에너지 영역에 대한 각 검출기의 자체 및 측정 환경 백그라운드, 측정 효율, 그리고 에너지 분해능 특성을 바탕으로 비교 분석되었다.

광학 설계 및 해석 프로그램인 ZEMAX에 대한 소개

이준호,Lee, Jun-Ho 한국광학회 2006 광학과 기술 Vol.10 No.4

택란약침(澤蘭藥鍼)이 Collagen으로 유발(誘發)시킨 관절염(關節炎)에 미치는 영향(影響)

이준호,이병렬,Lee, Jun-ho,Lee, Byung-Ryul 대한침구의학회 2000 대한침구의학회지 Vol.17 No.1

The purpose of this study is to observe the effect of Aqua-acupuncture utilizing Lycopi Herba Solution(LH-AS) on arthritis. For that purpose, we formed three experimental group, synovial cells of human body, normal BALB/C mice and DBA/1J mice with collagen II-induced arthritis, and measured the treatment effect of LH-AS on each group. The conclusions are as follows. 1. After the LH-AS treatment on synovial cells, there were no significant change in 1, 10, 50 and $100{\mu}g/m{\ell}$ whereas there was significant change in 200 and $400{\mu}g/m{\ell}$ in cytotoxicity. 2. IL-6, IL-$1{\beta}$, TNF-${\alpha}$ gene expression of synovial cells and the secretion amount of IL-6 and IL-$1{\beta}$ are significantly inhibited in treatment group with LH-AS. 3. The proliferation of synovial cells was significantly inhibited in treatment group with rIL-6, LH-AS 200 and rIL-6, $100{\mu}g/m{\ell}$. 4. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, the incidence of arthritis, hind paw edema, the index of arthritis and DTH were significantly inhibited. 5. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, splenetic weight was significantly increased and the number of leukocyte was significantly decreased. But there was no significant change in the number of platelet. 6. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, the number of $CD4^+$, $CD8^+$ activated cells and the surface-receptor expression were significantly increased whereas the number of $CD19^+$ activated cells and the surface-receptor expression were decreased. 7. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, total protein, LDH were significantly decreased, but there was no significant change in creatinine. 8. After the normal splenetic cells of BALB/C mice were treated by LH-AS and cultured, it was observed that the adherent cells were morphologically activated and IL-12 and IFN-${\gamma}$ gene expression were increased. 9. After the normal splenetic cells of BALB/C mice were treated by LH-AS and cultured, the number of $CD4^+$, $CD8^+$, $CD19^+$ activated cells and surface-receptor expression were inhibited when being compared with the control group. Taking all these observations into account, LH-AS injection is considered to be effective in treating arthritis and put to practical use in future arthritis clinic.

경화 위축성 태선과 경피증의 감별진단에 있어서 렉틴의 의의

이준호,문두찬,권경술,정태안 ( Joon Ho Lee,Doo Chan Moon,Kyung Sool Kwon,Tae Ahn Chung ) 대한피부과학회 1993 大韓皮膚科學會誌 Vol.31 No.3

Background : Differential diagnosis of lichen sclerosus et atrophicus( SA) and scleroderma is occasionally difficult. Objective : The purpose of this study was to attempt differentiation between the two diseases using imrnunohistochemical stain and lectins. Methods : Paraffin-embeddred sections of 4 cases of LSA and 11 cases of scleroderma were evaluated for this study. Using lectins, such as peanut agglutinin(PNA), siybean agglutinin(SBA), Ulex europaeus agglutinin-I(UEA-I) and Dolichos biflorus agglutinin(DBA) and the avidin-biotin-peroxi-dase complex(ABC) technique, differential lectin binding patterns betv een the two diseases were examined. Results : In the case of LSA, PNA and SBA stained the upper and lower spinous layer of the epidermis, and UEA I also stained the spinous layer of the epidermis weakly, but no DBA was stained. In the case of scleroderma, PNA stained not only the spinous layer but also the basal layer, SBA stained the upper half of the spinous layer but not the lower half of the pinous layer of epidermis. But UEA-I stained the vascular endothelial cells of dermis instead of epidermis, and DBA stained only the basal layer of epidermis. Conclusion : Staining of these 4 lectins on paraffin-embedded sectians using ABC teehnique could be helpful in differenting LSA and scleroderma. (Kor J Dermatol 1993; 31(3): 329-336)

임플란트 직경이 골유착에 미치는 영향에 관한 연구

이준호,신상완,권상호,Lee Jun-Ho,Shin Sang-Wan,Kwon Sang-Ho 대한치과보철학회 2003 대한치과보철학회지 Vol.41 No.2

Statement of problem : The survival rate of wide diameter implants was lower than of 3.75-mm implants in some clinical researches. Purpose : The purpose of this study was to investigate the influence of implant diameter on the osseointegration of implants in the rabbit femoral condyle and tibial metaphyses by means of removal torque measurements and histomorphometric analysis. Material and Method : Ten adult New Zealand White rabbits were used in this study Two 3.75-mm diameter implants were inserted through one cortical layer in the tibial metaphyses and one 3.75-mm diameter implant was inserted in the femoral condyle. 5.0-mm diameter implants were inserted in the other leg in the same manner. A total of 60 implants (3.75-mm diameter implants:30 : 5.0-mm diameter implants:30) were installed. After a healing time of 4 and 12 weeks, the peak removal torque values required to shear off the implants were recorded. From the removal torque values (Ncm) obtained, the mean shear stress ($N/mm^2$) was calculated. And the percentage of direct bone-to-implant contact and the percentage of bone area inside the thread were measured by Kappa Image Base-metreo. The Student's t-test was undertaken for statistical analysis (p<0.05). Results : The removal torque value of 5.0-mm diameter implants was higher than of 3.75-mm diameter implants (p<0.05). The difference of shear stress value between 3.75-mm and 5.0-mm diameter implants was not statistically significant (p>0.05). The percentage direct bone-to-implant contact had no statistical difference between two groups (p>0.05). The percentage of bone area inside the thread had no statistical difference between two groups (p>0.05). Conclusion It is concluded that the quality f osseointegration is not influenced by increasing implant diameter.

확대 영상의 몽롱화 현상을 제거하기 위한 보간 알고리즘 연구

이준호,Lee, Jun-Ho 한국생산제조학회 2010 한국생산제조학회지 Vol.25 No.6

This paper analyzes the problems that occurred in the magnification process for a fine input image and investigates a method to improve the blurring of magnified image. This paper applies a curve interpolation algorithm in CAD/CAM for the same test images with the existing image algorithm in order to improve the blurring of magnified image. As a result, the nearest neighbor interpolation, which is the most frequently applied algorithm for the existing image interpolation algorithm, shows that the identification of a magnified image is not possible. Therefore, this study examines an interpolation of gray-level data by applying a low-pass spatial filter and verifies that a bilinear interpolation presents a lack of property that accentuates the boundary of the image where the image is largely changed. The periodic B-spline interpolation algorithm used for curve interpolation in CAD/CAM can remove the blurring but shows a problem of obscuration, and the Ferguson' curve interpolation algorithm shows a more sharpened image than that of the periodic B-spline algorithm. For the future study, hereafter, this study will develop an interpolation algorithm that has an excellent improvement for the boundary of the image and continuous and flexible property by using the NURBS, Ferguson' complex surface, and Bezier surface used in CAD/CAM engineering based on the results of this study.