선천성 좌내경동맥 부재 1예

김응규,김동선,김종환,김성은,허경 인제대학교 1998 仁濟醫學 Vol.19 No.1

선천성 내경동맥부전 및 발육부전은 매우 희귀한 질환으로 전세계적으로 약 100예가 보고되고 있다. 이 질환은 뇌의 동맥류도 같이 동반하는 경우도 있으며 증상이 없이 지내는 경우도 있다. 본 저자 등은 두통을 주소로 내원한 43세 여자 환자에서 좌내경동맥의 선천적 부전을 전산화단층촬영을 통하여 확진하였기에 보고하는 바이다. Congenital absence of the internal carotid artery is a rare anomaly. When the internal carotid artery is congenitally absent, collateral circulation develops through the circle of Willis from basilar and the opposite internal carotid to supply the involved hemisphere. Absence or hypoplasia of the carotid canal on a computed tomography through the skull base should suggest a congenital ICA abnormality and prompt a search for associated intracranial vascular abnormalities because of high association with circle of Willis aneurysmal formation. A 43-year-old female patient listed to our hospital because of headache. There was no definite abnormal findings on neurologic examination. MRI did not show left intracranial portion of ICA, so we studied 4 vessel angiography. Angiography showed left ICA was not present and left MCA and left ACA was supplied by left posterior communicating artery and right AComA, respectively. Computed Tomography confirmed the absence of left carotid canal.

장관골에 발생한 거대세포 종양의 국소 재발에 관한 연구

김인,김정만,이승구,장한,김용식,김성수,한창환,김형관 가톨릭 중앙의료원 가톨릭 암센터 1991 가톨릭 암센터 論集 Vol.5 No.1

관상동맥 시술 도중 발생한 좌주간부 관상동맥 박리에 대한 스텐트 삽입 치료의 단장기 임상 결과 : acute and long-term results

이세환,이승환,홍명기,김영학,이철환,한기훈,송종민,강덕현,송재관,김재중,박성욱,박승정 대한내과학회 2004 대한내과학회지 Vol.66 No.6

목적 : 심도자 사용 시술과 관련된 좌주간부 관상동맥박리에 대한 적절한 치료는 아직 확실히 정립되지 않은 상태이다. 이에 본 연구는 좌주간부 관상동맥 박리에 대한 스텐트 삽입술의 단장기 임상결과를 후향적으로 분석하였다. 방법 : 좌주간부 관상동맥 박리에 대한 치료로 즉각적인 스텐트 삽입술을 시행하는 것이 안전하고 효과적인 방법임을 가설하였고, 이러한 즉각적인 스텐트 삽입을 시행한 10명의 환자를 대상으로 단장기적 임상경과를 의무기록 고찰과 전화 면담을 통해서 평가하였다. 결과 : 전체 환자 모두 처음부터 좌주간부 관상동맥에 유의한 협착을 가진 환자는 없었으며, 8명의 환자는 심도자의 조작으로 인한 박리가 발생한 경우였고(진단적 혈관 조영술 중에 3명, 유도 도자 조작 중에 5명), 나머지 2명은 다른 병변에 스텐트 삽입시술을 하는 중에 박리가 발생하였다. 이 10명의 환자에서 모두 즉각적인 스텐트 삽입술이 시행되었고, 4명의 환자에서 시술 도중 혈압 저하로 Intra-aortic Ballon Pump (IABP)를 장착하였다. 모든 환자에서 성공적으로 스텐트가 삽입되었고, 병원내 사망은 1명도 없었다. 6개월 추적 관상동맥 조영술은 8명의 환자에서 시행되었다. 혈관 조영상의 재협착(직경 협착 50% 이상)은 8명 모두에게서 관찰되지 않았으며, 퇴원 후 평균 31±25개월의 추적관찰 결과 주요 심장사건은 1건도 발생하지 않았다. 결론 : 비록 대상 환자가 적은 연구였지만 좌주간부 관상동맥 박리에 대한 스텐트 삽입술은 기술적으로 안전하고 빠르게 시행 할 수 있으며, 훌륭한 단장기적인 치료 효과를 보여준다. Background : The optimal treatment of patients with left main coronary artery (LMCA) dissection during catheter-based procedure remains uncertain. We retrospectively analyzed the acute and long-term results of bail-out stenting for LMCA dissection. Methods : In cases with significant LMCA dissection occurring during catheter-based procedure, prompt stent implantation may be safe and associated with favorable clinical outcome. We evaluated the acute and long-term results of bail-out stenting for LMCA dissection occurring during catheter-bases procedure in 1- patients. Results : Initially, there was significant stenosis of LMCA segment in these patients. Catheter-induced dissection occurred in 8 patients (during diagnostic angiography in 3 patients and guiding catheter manipulation in 5 patients). Two patients suffered dissection in the setting of stent deployment in other vessels. Therefore, bail-out stenting LMCA dissection was performed in a total of 10 patients. In 4 patients, hypotension developed and intra-aortic balloon pump was placed during procedure. Stents were successfully deployed in all patients. There was no in-hospital mortality. Six-month angiographic follow-up was performed in 8 patients. Angiographic restenosis(diameter stenosis 50%) was not observed in all patients at follow-up study. During a mean follow-up of 31±25 months after hospital discharge, there was no major adverse cardiac event (death, myocardial infarction, and target lesion revascularization). Conclusion : Bail-out LMCA stenting is technically feasible, and showed good acute and long-term results in a small series of patients.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.

중학교 과학 수업에서 협동을 위한 협동학습 모형의 적용 방안 연구

김인환,이승민,차정호 대구대학교 2006 대구대학교 학술논문집 Vol.1 No.2

과학 수업을 더욱 의미 있는 학습 경험으로 구성하기 위해서는 학생들의 능동적인 수업참여와 활발한 토의를 유도할 수 있는 교수-학습 전략이나 학습 환경에 대한 연구가 필요하다. 우리나라에서는 다양한 협동학습 방법이 소개되었으나 과학과에 적용된 수업 모형으로는 STAD, LT, Jigsaw, 등에 국한되어 있는 것으로 나타나고 있다. 따라서 과학과 수업에 적용해 볼 수 있는 좀 더 변화된 수업 모형 적용에 관하여 연구해 볼 필요가 있다. 본 연구에서는 학생들 사이의 협동기술을 증진시킬 수 있는 과학과에서의 새로운 협동학습 모형으로 협동을 위한 협동학습(Co-op Co-op)모형을 선정하여 적용가능성을 탐색해 보고 일선 교육 현장에서 곧바로 활용할 수 있는 교수-학습 자료를 개발하고자 하였다. 이 수업 모형이 중학교 과학과에 적합한지, 중학교 교과 수업에 적합한지, 중학교 교과에 적용시 기대되는 효과는 어떠한 것들이 있는지에 관하여 검토하였으며, 중학교 과학1 교과 '물질의 세가지 상태' 단원을 적용시켜 6차시 분량의 수업지도안과 탐구 활동지를 개발하였다. 협동을 위한 협동학습(Co-op Co-op)모형은 교사들이 교단에서 쉽게 적용할 수 있는 수업 모형으로 적절히 사용한다면 과학 수업에서 결여된 협동성과 사회성이 가미되어 과학과 탐구 실험 활동에서 보다 나은 참여와 효과적인 수업이 될 수 있다고 생각된다. 본 연구에서는 중학교 교과에서 협동을 위한 협동학습(Co-op Co-op)모형의 적용가능성을 검토했지만, 더 나아가 고등학교 교과에 적용 시킬 수 있는 연구도 요구된다. A study is needed on strategies or learning environment to form science classes as meaningful learning experience. In our country, various methods of cooperative learning have been introduced, but learning models applied in the science subject are limited in STAD, LT, Jigsaw, etc. Thus, it is neccessary to study application of more changed learning models for science classes. In this study, Co-op Co-op model was selected as a new cooperative learning model to promote cooperative technique between students in the science subject and its applicability was examined. Based on this process, this study purposed to develop teaching-learning material which can be directly used in the educational field. Accordingly, whether this learning model is suitable to the science subject of middle school was examined. Laying emphasis on whether Co-op Co-op model is fit for the science subject and classes of middle schools, and what effects are expected when it is applied in subjects of middle schools, a study and an analysis were conducted and teaching plan, research activity sheet and assessment sheet of the sixth session were developed by applying it in the unit of "three states of material" of the science subject of middle schools. Co-op Co-op model should be conducted with a class model which is fit for our actual situations and the most suitable to students, and teachers easily apply in the class instead of applying cooperative learning in science classes unconditionally. If this is implemented, cooperation spirit and sociality that science classes lack in are added and it is expected that better participation and effective learning are performed in experimental activity. In this study, applicability of Co-op Co-op model was examined only in subjects of middle schools, alternative plans are demanded to apply it in subjects of high schools.

긴 관동맥병변에서 긴 스텐트삽입에 대한 임상경과 및 재협착율

김영학,박성욱,정상식,박훈기,이상곤,이일수,이철환,김재중,홍명기,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

Asphyxiating Thoracic Dystrophy 1례

김영유,이승철,이수중,한지환,황성수,이경일 최신의학사 1992 最新醫學 Vol.35 No.6

복합 관동맥병변에서의 Rotational Atherectomy : 초기결과

김진우,박성욱,홍명기,이상곤,이일수,이철환,최기준,강덕현,송재관,김재중,박승정 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.9

탄소/폴리이미드(C/PI) 복합방적사의 제조조건에 따른 특성변화

김규호,주창환,이승구 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.2

We have investigated the effects of manufacturing conditions on the morphological structure and physical properties of the carbon-core/polyimide-sheath(C/PI) composite yam manufactured by the DREF 2 friction spinning machine. The C/PI composite yam produced can be applied to the various fields of requiring high strength and high heat resistance, such as gloves, bullet-proof jackets and so on. The results obtained in this study are as follows; Breaking stress and initial modulus of the C/PI composite yams have increasing trends, and breaking strain has decreasing trend with the increase of heating temperature and time. The cohesion of drawn sliver in higher than that of carded sliver, the PC/PI composite yams show the trend that the breaking stress and initial modulus are similar to C/PI composite yams. Moreover, as twist level increases, breakage occurs on the core(carbon filament) and th breaking stress significantly decreases. Peeling strength of PC/PIF composite yams increases, as the bonding force of PET, filament increases with increasing the heating time. Slippage resistance on the sheath of C/PI composite yam increases with increasing heating temperature and time, and surface and cross-section structure of C/PI composite yams have increasing cohesion with the increase of heating temperature and time

원발성 폐암 환자의 생존율에 관한 보고

김현태,이상무,어수택,박춘식,정성환,허승재,남충희,강창희,김용훈 순천향대학교 1994 논문집 Vol.17 No.4

We analysed 404 patients with primary lung carcinoma who were treated at Soonchunhyang University Hospital from July, 1985 to september, 1993 in order to investigate the survival rate and epidemiolgical properties of primary lung cancer. They were 330 males and 74 females. The most prevalent decade was seventh. In terms of cell type, the squamous cell was 225 patients (55%), and adenocarcinoma, small cell, mixed type was 21%, 19%, 4%, respectively. Among non-small cell lung carcinoma, stage Ⅲa was the most prevalent one(92%). In case of small cell carcinoma, the limited stage was 64%. The 12-, 24-, 36- month survival rate of total patients was 57%, 31%, 22%, respectivley and median sruvival time was 15 months. The 36-month survival rate tended to be longer in non-small cell lung carcinoma than that of small cell lung cancer, but there was no difference between two groups, statistically. In non-small cell carcinoma, The 36-month survival rate and meidan survival time were longer in the stage Ⅰ and Ⅱ than those of Ⅲa, Ⅲb, Ⅳ (80% versus 38%, 22%, 0%, p<0.05). According to involvement of lymph node, the 36-month survival rate was longer in NO and N1 than those of N2, N3 (61.9%, 48.7% versus 17.7%, 17.3%, p<0.05). In small cell carcinoma, The 36-month survival rate and median survival rate were higher and longer in limited stage than those of extensive stage(16.1% and 13 month vs 10% and 8 month, p<0.05). In conclusion, we report here the incidence of primary lung carcinoma and the survival rate of paients with primary lung carcinoma who were treated in Soonchunhyang University Hospital.