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이승환,박병문,송경섭,이수건,윤상필,이재철,이범석,양봉석 대한척추외과학회 2017 대한척추외과학회지 Vol.24 No.1
Study design: Retrospective study. Objectives: The goal of this study was to evaluate the risk factors of osteoporotic vertebral fractures (OVFs) in patients with Cushing syndrome. Summary of Literature review: In most reports, vertebral fractures in Cushing syndrome have been found to be related to osteoporosis. However, few studies have analyzed the clinical risk factors for OVFs. Materials and Methods: Thirty-two patients with Cushing syndrome who visited the orthopaedic department complaining of back pain were included in this study. Standing lateral X-rays were performed to evaluate the presence of vertebral fractures, and bone mineral density (BMD) was measured. Results: Of the 32 patients with Cushing syndrome with back pain, 8 (25%) were diagnosed with OVFs using morphometric criteria. The average weight and body mass index of the vertebral fracture group (VF group) were significantly higher than the values observed in the non-vertebral fracture group (non-VF group) (p=0.004, p=0.018). Lumbar BMD was significantly lower in the VF group (p=0.006). A risk factor for OVFs in Cushing syndrome was osteoporosis (odds ratio=18.56, 95% confidence interval=1.72-200.21, p=0.016) regardless of gender, obesity, menopause, or urine free cortisol levels. Conclusions: OVFs in Cushing syndrome have been associated with overweight, and overweight is an indicator of compliance in the treatment of Cushing syndrome. Therefore, weight reduction and the prevention of osteoporosis should be emphasized in patients with Cushing syndrome to prevent OVFs. 쿠싱 증후군에서 골다공증성 척추 골절의 위험 인자이승환 • 박병문 • 송경섭 • 이수건 • 윤상필 • 이재철 • 이범석 • 양봉석광명성애병원 정형외과연구 계획: 후향적 연구목적: 쿠싱 증후군에서 증상이 있는 골다공증성 척추 골절의 유병률을 조사하고, 골다공증성 척추 골절의 위험 인자를 분석하였다. 선행문헌의 요약: 쿠싱 증후군에서 척추 골절은 대부분은 골다공증과 연관이 있었다. 그러나 척추 골절의 다른 위험 인자에 대해 분석한 연구는 거의 없었다. 대상 및 방법: 요통으로 정형외과 외래에 내원한 32명의 쿠싱 증후군 환자를 대상으로 하였다. 흉요추부 기립위 측면 방사선을 촬영하여 척추 골절을 진단하였고, 척추와 대퇴 경부의 골밀도를 측정하였다. 척추 골절 그룹과 비골절 그룹의 통계학적 차이를 paired t-test를 이용해 비교하였고, 위험인자 분석을 위해 로지스틱 회귀 분석을 사용하였다. 결과: 전체 32명의 환자중 8명(25%)의 환자에서 골다공증성 척추 골절이 확인되었다. 척추 골절군의 평균 체중과 체질량 지수가 비골절군에 비해 유의하게 높았으며(p=0.004, p=0.018), 척추 골절군의 요추부 골밀도가 비골절군에 비해 유의하게 낮았다(p=0.006). 골다공증성 척추 골절의 위험 인자는 골다공증으로 나타났다(odds ratio 18.56, 95%CI 1.72-200.21, p=0.016). 결론: 쿠싱 증후군 환자에서 척추 골절의 발생은 과체중과 관련이 있으며, 과체중은 평소 쿠싱 증후군의 부적절한 치료로 인한 상태를 반영하는 지표라고할수 있다. 그러므로, 적절한 내분비적 치료를 통계 적정 체질량을 유지하고, 골다공증의 약물 치료를 병행하는 것이 쿠싱 증후군의 척추 골절 예방에 중요하다고 하겠다. 색인 단어: 쿠싱 증후군, 척추 골절, 골다공증약칭 제목: 쿠싱 증후군과 척추 골절
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이승환,노현모 한국유전학회 1985 Genes & Genomics Vol.7 No.1
The clonings of Pst I restriction-modification system were reproted in two cases. One was by Walder et al. (1981) and the other was by Lee et al. (1982). pRL 829 constructed by Lee et al. was a recombinant plasmid containing 3.7kb insert fragment at Hind III site of pBR 322, which encoded whole Pst I restriction-modification system. In this research, a new recombinant plasmid, pRL 830, containing only Pst I methylase gene was constructed from pRL 829 by partial digestion with Hinc II. pRL 830 contained 2.2kb insert DNA out of 3.7kb insert of pRL 829. The host DNA and plasmid from the cells transformed with pRL 830 were not cleaved by Pst I, suggesting that Pst I methylase gene was cloned and expressed in the cells. However, E. coli transformed with pRL 830 was easily infected and lysed by bacteriophage Ø80, indicating that Pst I endonuclease gene was at least inactivated or removed from pRL 830. Soluble fractions from the E. coli containing pRL 830 were passed through the DEADEN-cellulose and phosphocellulose columns. Eluted enzyme fraction with salt gradient were assayed for the Pst I endonuclease and methylase activities. Results showed that Pst I methylase activity was detected, where-as Pst I endonuclease activity was not. It was convinced pRL 830 encoded Pst I methylase gene, but not endonuclease gene.
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이승환,조형기,박노길 대한교통학회 1997 大韓交通學會誌 Vol.15 No.4
본 연구는 교차로의 접근로에서 영상처리 기반의 실시간 대기길이 계측알고리즘을 개발하는데 그 목적이 있다. 이 알고리즘은 경계선추출기법에 기초하여 개발되었으며, 주간 및 야간의 환경하에서 현장실험을 통하여 평가되었다. 실험결과 주간의 환경보다 야간의 환경에서 더 좋은 결과를 얻었다. 대기길이의 계측에 있어서 최대오차는 8m였으며, 대기길이계측 범위를 100m로 했을 때 4m내에서 오차가 발생하였다. 본 알고리즘으로 대기길이를 계측하는데 있어서 한 프래임당 소요된 상처리 시간은 펜티엄 75㎒ 환경하에서 약 0.125초에서 0.143초가 소요되었다. 본 연구의 수행결과 대기길이 계측을 위하여 실시간 처리가 가능할 것으로 판단되며, 향후 이에 성능향상을 위한 보완과 기능적 확장에 관한 부대연구가 요구된다.
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이승환,이성재,이원용 한국목재공학회 1993 목재공학 Vol.21 No.4
In the present paper, we discribed distributions patterns of pits on the tracheids of Pinus koraiensis. The number of bordered pits on a tracheid is more numerous than that of cross-field pittings. And they appeared different in the number depending on the shape and size of tracheids. Both pit and cross-field pitting on a tracheid is fewer in number near the pith. The number of bordered pits on the tracheid increased rapidly from pith toward cambial zone but that of cross-field pittings increased gradually. The number of bordered pit and corns-field pitting is more frequent in the first-formed tracheid, and the number of bordered pit decreased rapidly from earlywood to latewood but that of corss-field pittings decreased gradually. Bordered pits on a tracheid are more numerous at the end of tracheids and cross-field pittings occur more frequently in the center part of a tracheid.
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이승환,조한선,최기주 대한교통학회 1996 大韓交通學會誌 Vol.14 No.1
This paper presents a heuristic algorithm for classifying vehicles using a single loop detector. The data used for the development of the algorithm are the frequency variation of a vehicle sensored from the circle-shaped loop detectors which are normal buried beneath the expressway. The pre-processing of data is required for the development of the algorithm that actually consists of two parts. One is both normalization of occupancy time and that with frequency variation, the other is finding of an adaptable number of sample size for each vehicle category and calculation of average value of normalized frequencies along with occupancy time that will be stored for comparison. Then, detected values are compared with those stored data to locate the most fitted pattern. After the normalization process, we developed some frameworks for comparison schemes. The fitted scales used were 10 and 15 frames in occupancy time(X-axis) and 10 and 15 frames in frequency variation (Y-axis). A combination of X-Y 10-15 frame turned out to be the most efficient scale of normalization producing 96 percent correct classification rate for six types of vehicle.
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