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이동성 홍반의 피부 병변으로 내원한 환자들에 대한 고찰
오윤석 ( Yoon Seok Oh ),엄민섭 ( Min Seob Eom ),조미연 ( Mee Yon Cho ),김종배 ( Jong Bae Kim ),최응호 ( Eung Ho Choi ) 대한피부과학회 2008 大韓皮膚科學會誌 Vol.46 No.5
Background: Lyme disease, an infection caused by Borrelia(B.) burgdorferi, has been reported in many countries. But in Korea, only 5 cases of serologically diagnosed lyme disease have been reported. Because several strains of B. burgdorferi were isolated from Ixodes ticks which were captured in Kangwon and Chungbuk province, there might be more cases of serologically undiagnosed lyme diseases presenting with erythema migrans. Objective: To understand the clinical patterns and laboratory findings of erythema migrans in Korea. Methods: A clinical survey was retrospectively performed on 9 patients with erythema migrans which occurred after tick bites. Results: Among 9 patients with erythema migrans, 3 patients were male and 6 patients were female. The onset age of erythema migrans ranged from 26 to 71 years old (mean, 51.3 years old). The mean duration of erythema migrans after tick bite was 26.4 days and the diameter of the lesion ranged from 6 to 34 cm (mean, 18.3 cm). All cases developed from May to September and systemic symptoms such as fatigue, fever and/or chills, myalgia, palpitation, headache, arthralgia and dyspnea were present at the time of hospital visits of 3 patients. Clinically, 3 patterns of erythema migrans were seen; typical target pattern, homogenous and erythematous plaque pattern, and linear solitary plaque pattern with central postinflammatory pigmentation. Only 2 of the 7 patients (28.6%) were seropositive for IgM and IgG antibody titers by enzyme-linked immunosorbent assay in consecutive serologic tests. PCR for Borrelia DNA in paraffin-embedded tissue showed full negativity in 6 patients with erythema migrans. Conclusion: Although lyme disease is not endemic in Korea, some patients with erythema migrans might be undiagnosed as lyme disease serologically with erythema migrans. To take into consideration false negative serelogic results in early erythema migrans, early oral tetracycline therapy should be included through clinical and historical diagnosis. (Korean J Dermatol 2008;46(5):596∼603)
김건욱(Kuhn Uk Kim),조미연(Mee Yon Cho),조남천(Nam Cheon Cho),윤광수(Kwang Soo Yoon),김대성(Dae Sung Kim),노병선(Byoung Seon Rhoe) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5
Adenosquamous carcinoma of the pancreas has a mixture of adenocarcinoma and squamous cell carcinoma components and is uncommon. We presents one case of adenosquamous carci- noma of the pancreas in old man aged 76. His chief cornplains were intermittent abdorninal discomfort and pain. Physical examination revealed huge abdominal mass in left upper quad- rant abdomen. All laboratory data were not significant. Abdominal ultrasonography and CT scan revealed a well demarcated cystic and solid mass which was located at the tail of the pancreas. Successful resection of the tumor by splenectomy, total gastrectomy and segmental resection of transverse colon were carried out. Cut section of the resected specimen reveals a huge cyst locating between the serosal surface of the stomach and pancreas and an oval round solid mass with infiltrating margin of the distal pancreas. Histopathologically, the tumor was composed of adenocarcinorna, well differentiated squamous cell carcinoma and anaplastic car- cinoma with transition areas. The cyst was partly lined by mesothelial cells and poorly differentiated squamous cell carcinoma. The patient was discharged without specific prob- lem. But he died 6 months after operation.(Korean J Gastroenterol 1994; 26: 885 891)
제 I 형 신경섬유종증에 병발하였던 종격동내 횡문근육종에 의한 척수압박 1례 - 증례보고 -
김세윤,황금,홍순기,변진수,허철,김헌주,한용표,이명섭,이종국,조미연,Kim, Sei-Yoon,Whang, Kum,Hong, Soon-Ki,Pyen, Jhin-Soo,Hu, Chul,Kim, Hun-Joo,Han, Young-Pyo,Lee, Myoung-Sup,Lee, Chong-Kook,Cho, Mee-Yon 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.5
A 12-years-old female admitted to the hospital with the complaint of pain on the right upper chest area which persisted about 1 month prior to admission. $Caf{\acute{e}}$-au-lait spots of various size laying on a whole body and freckling on the axilla were found on physical examination. A huge mass was found on the plain chest X-ray and on chest MRI. The mass encroached thoracic spine, posterior rib, back muscles, and then into the neural canal and compressed thoracic spinal cord. On the 5th day of hospitalization, the patient complained tingling on the both legs and 2 days later, monoparesis on the right leg. Open thoracotomy and decompressive laminectomy was done to remove mass. Pathologic reports confirmed rhabdomyosarcoma, embryonal type.
황성관,박희전,윤여승,나중호,오진록,김기호,김동진,양경무,조미연,Hwang, Sung-Kwan,Park, Heui-Jeon,Yoon, Yeo-Seung,Rha, Jung-Ho,Oh, Jin-Rok,Kim, Ki-Ho,Kim, Dong-Jin,Yang, Kyung-Moo,Cho, Mee-Yon 대한근골격종양학회 1998 대한골관절종양학회지 Vol.4 No.1
Osteosarcoma is the most common primary bone tumor except for multiple myeloma. Hematogenous spread of osteosarcoma presents the t1susal route of dissemination. Lung metastasis is the most common, however the lymph node involvement is quite rare. In addition, according to Mirra, radiologically detectable involvement of lymph node is an extremely rare manifestation of osteosarcoma. The authors had experienced a patient with an osteosarcoma of the right distal femur which spread to the right inguinal lymph node and lung. After preoperative chemotheraphy, a limb salvage operation was performed around the lesion of right distal femur and the right inguinal lymph nodes were dissected. A adjuvant postoperative chemotheraphy was performed. After the treatment, there was no recurrence of osteosarcoma or any other metastatic evidence for two years and 8 months.
이태환,김헌주,허철,한용표,홍순기,변진수,김명순,조미연,김윤미 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.11
in recent times, central nervous system(CNS) tuberculosis has been rare and the prevalence of the focal form, the tuberculoma, varies from 1 per 200 to 1 per 1000. CNS tuberculosis occurs as a result of hematogenous spread from a primary focus. mostly pulmonary tuberculosis. It can be diffuse exudative leptomeningitis or a localized tuberculoma ; the former is more common. We report a case of miliary cerebral tuberculosis in a 24-year-old female who had been having headaches for 4 months. Magnetic resonance imaging showed numerous small round Gadolinium-enhanced supratentorial and infratentorial lesions scattered throughout the brain. Histologic examination confirmed well defined tuberculous granulomas with central caseous necrosis in open biopsy, containing several acid-fast bacilli, the patient was treated with isoniazid, rifampin, ethambutol, pyrazinamide in combination with prednisolone.