2001년 경상북도에서 발생한 콜레라 유행에 관한 역학조사

이준호,이관,김준철,이상원,고운영,양병국,이종구,김문식,임현술,Lee, Jun-Ho,Lee, Kwan,Kim, Jun-Chul,Lee, Sang-Won,Go, Un-Yeong,Yang, Byung-Kuk,Lee, Jong-Koo,Kim, Moon-Sik,Lim, Hyun-Sul 대한예방의학회 2002 예방의학회지 Vol.35 No.4

Objectives : This study was carried out to investigate the cause, magnitude and transmission route of the cholera outbreak in 2001 Methods : The study population were those persons who ingested foods at the restaurant, were confirmed as cholera patients, had symptoms of diarrhea and sewed as workers at the restaurant. A questionnaire survey and microbiological examinations on the microbes isolated from rectal swabs were conducted. Of the cases, 316 food histories were surveyed by an analysis of the restaurant menu. Results : There were 139 confirmed cases of cholera reported in Korea in 2001. Of these, 104 were related to the restaurant. By region, Gyeongsangbuk-do had the highest incidence with 91 cases. Of these 91 cases, 74 had ingested foods at the restaurant, 2 were employees and 3 were secondary infection cases within the families. The results of the odds ratio analysis of the 316 persons having ingested foods at the restaurant were as follows: sandwiches 5.07 (95% CI, 1.85-14.59), soybean curd 2.45 (95% CI, 1.09-5.56), noodles 2.34 (95% CI, 1.24-4.42), steamed squid 2.01 (95% CI, 1.17-3.47) and vinegared rice 1.82 (95%, CI, 1.08-3.09). It was certain the restaurant in question was the cause of the 2001 outbreak. Conclusions : We suspected that more than one restaurant employee contaminated foods served at the restaurant. In addition, eating raw fishes purchased at the Pohang Fisheries infected the employees of the restaurant. There is a possibility that these raw fishes were themselves contaminated by cholera bacilli in the sea.

정맥용 면역글로불린 투여 후 발생한 무균성 수막염 3례

이준호,송은경,이진아,김남희,김동호,박기원,최은화,이환종,Lee, Joon Ho,Song, Eun Kyoung,Lee, Jin A,Kim, Nam Hee,Kim, Dong Ho,Park, Ki Won,Choi, Eun Hwa,Lee, Hoan Jong 대한소아감염학회 2005 Pediatric Infection and Vaccine Vol.12 No.2

IVIG 투여에 의해 무균성 수막염은 그 기전이 밝혀지지 않았으나 IVIG 투여와 관련된 신경학적 부작용 중 가장 중한 합병증의 하나이다. 저자들은 서울대학교 어린이병원에서 2003년부터 2004년까지 3명의 환아에서 확인된 IVIG 투여와 관련된 무균성 수막염 4례를 경험하여 보고하였다. 3명의 환아는 ITP, 가와사키병, 중증 근무력증으로 기저질환은 각각 상이하였으나 기저질환에 대한 치료를 위해 모두 고용량의 IVIG를 투여받았으며, IVIG를 투여받은 후 1~2일 이내에 심한 두통과 뇌막자극 징후를 보였다. 척수액 소견상 백혈구 수는 $100/{\mu}L$ 미만에서부터 $1,000/{\mu}L$ 이상까지 다양하였으나 주로 다핵구로 구성된 척수액 백혈구 분포를 보였고(66~98%), 세균 배양검사와 장바이러스 배양과 PCR 검사에서 음성 결과를 보였다. 3명의 환아 모두 수막염 발생 2일 후까지는 증상이 호전되었으며, 후유증 및 장애가 없었다. Intravenous immune globulin(IVIG) is widely used for immune thrombocytopenic purpura (ITP), Kawasaki disease and other autoimmune neuromuscular disease. Aseptic meningitis was one of the most serious neurologic complications reported following the use of IVIG. We experienced 4 episodes of aseptic meningitis associated with IVIG usage in 3 patients from 2003 to 2004. Underlying disease of each patients was ITP, Kawasaki disease and myathenia gravis and all of them received high dose IVIG treatment for their underlying disease. Within a days, they started to complain severe headache and diagnosed meningitis by cerebrospinal fluid analysis. Cerebrospinal fluid leukocyte counts varied from 92 to over a thound per microliter with dominance of polymorphonuclear leukocytes. Microbiologic studies revealed no organisms. All of them were free from headache within 2 days and did not suffer any neurological sequelae.

A 37Ch Visible Adaptive Optics System for Wavefront Compensation

이준호,Byung Tae Choi,Eung Cheol Kang,Hae Seog Kho,Ho Jung Cheon,Jae Il Lee,Joon Won Kim,Kyung Muk Lee,Sung Jin Kim,Young Cheol Lee,Young Il Cho 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.1

A visible adaptive system was developed to compensate for phase distortions of a visible (He-Ne) laser. The visible adaptive optics (AO) system consists of 5 subsystems: a Shack-Hartmann wavefront sensor, a deformable membrane mirror of 15 mm with 37 actuators, a high-speed tip/tilt mirror of 20 mm, a position sensor and a control & display unit. The lab-developed Shack-Hartmann sensor was experimentally shown to have a measurement accuracy of better than RMS /50 at 0.6328 μm over the maximum phase distortion that the deformable mirror could generate, i.e., approximately /4. The adaptive optics system operated the deformable mirror at 10 Hz and the tip/tilt mirror at 30 Hz, which were, respectively, closed by the Shack-Hartmann sensor and the position sensor. The closed adaptive optics system was demonstrated to compensate for time-varying wavefront aberrations of PV (Peak-to-Valley) 1.2 μm with a time frequency of 1.4 Hz. The residual RMS wavefront error was shown to be smaller than 0.014 μm, i.e., /45 at 0.6328 μm.

Experimental Evaluation of Q-Parameterization Control for the Imbalance Compensation of Magnetic Bearing Syatem

이준호,김현기,이정석,이기서,Lee, Jun-Ho,Kim, Hyeon-Gi,Lee, Jeong-Seok,Lee, Gi-Seo 대한전기학회 1999 전기학회논문지A Vol.48 No.3

This paper utilizes the method of Q-parameterization control to design a controller which solves the problem of imbalance in magnetic bearing systems. There are two methods to solve this problem using feedback controal. The first method is to compensate for the imbalance forces by generating opposing forces on the bearing surface (imbalance compensation). The second method is to make the rotor rotate around its axis of inertia (automatic balancing);in this case no imbalance forces will be generated. In this paper we deal with only imbalance compensation. The free parameter of the Q-parameterization controller is chosen such that these goals are achieved. After the introduction of a model of the magnetic bearing system, we explain the Q-parameterization controller design of the magnetic bearing system with emphasis on the rejection of sinusoidal disturbance for imbalance compensation design. The design objectives are formulated as a linear equations in the controller free paramete Q. Finally, simulation and experimental results are presented and showed the robustness and effectiveness of the proposed controllers.

원격전이를 동반하지 않은 4기 위암 환자의 예후

이준호,노성훈,최승호,민진식,Lee Jun Ho,Noh Sung Hoon,Choi Seung Ho,Min Jin Sik 대한위암학회 2001 대한위암학회지 Vol.1 No.2

Purpose: In the UICC staging system, stage IV contains not only those patients with distant metastasis but also patients with far advanced T and N status but without distant metastasis. We investigated the prognostic factors of stage IV gastric carcinoma patients without distant metastasis after curative resection. Materials and Methods: 190 stage IV gastric carcinoma patients without distant metastasis were reviewed after curative resection. Results: Male sex, distal third location, Borrmann type III, IV and histologically undifferentiated type were common. 5 year survival rate of the 190 patients was $22.2\%$. Depth of invasion and lymph node metastasis did not influence survival. The lymph node ratio (positive lymph node / retrieved lymph node) and combined resection affected survival by univariate and multivariate analysis. Conclusion: Combined resection and positive lymph node ratio were the independent prognostic factors in the patients with stage IV gastric carcinoma who underwent curative resection.

R&D 리포트 - "광학업체들, 위성탑재체 개발 참여로 첨단기술 확보 계기로 삼아야" - 우리기술.우리 탑재체, 과학기술위성 3호 지구관측 영상분광기 코미스(COMIS) -

이준호,Lee, Jun-Ho 한국광학기기산업협회 2009 光學世界 Vol.121 No.-

1980년 말에 시작한 우주개발에 참여한 우리나라는 약 20년이라는 짧은 시간 동안 급속하게 기술축적을 하여 위성체 개발 기술을 상당부분 보유하게 되었고, 오는 7월이면 KSLV-1의 발사를 통하여 우주진입 기술 확보도 시작하게 될 것으로 기대되고 있다. 과학기술위성 3호 영상분광기 코미스(COMIS)는 개발 과정도 하나의 목표로 취급되고 있어, 모든 개발 과정이 100% 국내에서 이뤄지고 있다. 특히, 광학 소자의 가공 및 평가에 국내 민수 광학 업체들이 참여하고 있다. 광학 업체의 위성탑재체 개발 참여를 통한 매출 증가는 아직 미비하지만 이를 통하여 초정밀 초청밀 가공 및 평가 기술, 초경량화 및 신소재, 환경평가 기술들을 확보하는 계기로 판단하여 적극적인 참여의지 표시가 필요할 것으로 보인다.

인간 수명과 노화, 조질 가능한가?

이준호,Lee, Jun-Ho 한국과학기술단체총연합회 2011 과학과 기술 Vol.511 No.-

치주질환과 관상동맥질환의 관련성에 대한 임상적 연구

이준호,정현주,김주한,Lee, Jun-Ho,Chung, Hyun-Ju,Kim, Ju-Han 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.1

Coronary heart disease is the leading cause of mortality in adult population. Whereas the association between periodontal disease and coronary heart disease (CHD) are controversial, recent studies reported the association between periodontal disease and acute myocardial infarction or prognosis of CHD. This study was aimed to investigate the relationship between periodontal disease and angiographically defined CHD, and acute myocardial infarction, and the prognosis of treated CHD. Patients under the age of 60 who had undergone the diagnostic coronary angiography were enrolled in this study, Subjects were classified as positive CHD (+CHD, n=37) with coronary artery stenosis more than 50% in at least one of major epicardial arteries, and negative CHD (-CHD, n=20) without stenosis. After recording the number of missing teeth, periodontal disease status was measured by means of plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL), Positive CHD subjects were classified into acute myocardial infarction group (AMI), and non-AMI with angina pectoris and old myocardial infarction. Six months postoperatively, positive CHD subjects were followed and had undergone the coronary angiography again. Even though there was no significant difference in the periodontal parameters and status between positive CHD and negative CHD, some periodontal parameters, such as mean probing depth and proportion of sites with probing depth greater than 4mm or 6mm were significantly different between AMI and Non-AMI(p<0.05). There was no significant difference in the periodontal parameters according to in angiographically follow-up status. These results indicate that periodontal disease may be associated with the occurrence of acute myocardial infarction.

국내 도시하천에 대한 식수허가지도의 적용성 검토

이준호,윤세의,Lee, Joon-Ho,Yoon, Sei-Eui 한국방재학회 2005 한국방재학회논문집 Vol.5 No.3

도시하천의 관리와 계획에 있어 식수에 따른 수리학적 특성의 변화는 명확히 분석되어야 한다. 본 연구에서는 도시하천의 식수기준을 분석하고, 도시하천의 고수부지내 식수가 가능한 지역을 표시한 식수허가지도 제작 방법을 검토하였다. 또한 식수에 따른 수리학적 영향을 준2차원 수치모형, HEC-RAS, FESWMS 모형을 활용하여 분석하였다 중랑천의 장안교부터 군자교까지의 구간을 대상으로 선정하여 100년 빈도 홍수량에 식수허가지도를 제작한 결과, 교목의 식수시에는 하천의 우안에 $0.5{\sim}1$본/ha 정도의 식수가 가능하였으며, 관목의 경우에는 좌안 및 우안의 중요수방구간을 제외한 지역에 식재가 가능하였다. 또한 관목의 식재에 따른 수리학적 영향은 약 12cm 정도의 수위상승 결과를 나타내었다. 따라서 대상구간에 식수에 따른 수위 상승은 적은 것으로 판단되므로 식수허가지도에 따라 식수가 가능할 것으로 판단된다. In order to design and manage the urban streams, the change of hydraulic characteristics by vegetation must be analyzed clearly. Planting criteria of vegetation in a urban stream were investigated and the design method of vegetation permission map was analyzed in this study. In addition, variations of water level due to vegetation are calculated by quasi two dimensional numerical model, HEC-RAS model and FESWMS model. Joongrang stream(Gunja bridge${\sim}$Jangan bridge reach) was selected as the case study stream. According to the criteria of vegetation, it is decided that vegetation density was $0.5{\sim}1.0$ tree/ha for selected tall tree in right floodplain and shrubs can be planted in the right and left floodplain area except the important hydraulic structures site. The selected shrubs planting simulations with three models show that water level in selected floodplain area increase approximately 12cm for the 100 year return period flood. The applicability of vegetation permission map in Korean urban stream was analyzed in this paper.

구법(灸法)의 양생보건(養生保健)에 관(關)한 문헌적(文獻的) 고찰(考察)

이준호,이병렬,Lee, Jun-Ho,Lee, Byeong-Ryeol 대전대학교 한의학연구소 1997 한의학연구소 논문집 Vol.6 No.1