[NEWS] 신진연구자 소개_이준호 Joon-Ho Lee

이준호(Joon-Ho Lee) 대한화학회 2023 화학세계 Vol.63 No.5

정맥용 면역글로불린 투여 후 발생한 무균성 수막염 3례

이준호,송은경,이진아,김남희,김동호,박기원,최은화,이환종,Lee, Joon Ho,Song, Eun Kyoung,Lee, Jin A,Kim, Nam Hee,Kim, Dong Ho,Park, Ki Won,Choi, Eun Hwa,Lee, Hoan Jong 대한소아감염학회 2005 Pediatric Infection and Vaccine Vol.12 No.2

Intravenous immune globulin(IVIG) is widely used for immune thrombocytopenic purpura (ITP), Kawasaki disease and other autoimmune neuromuscular disease. Aseptic meningitis was one of the most serious neurologic complications reported following the use of IVIG. We experienced 4 episodes of aseptic meningitis associated with IVIG usage in 3 patients from 2003 to 2004. Underlying disease of each patients was ITP, Kawasaki disease and myathenia gravis and all of them received high dose IVIG treatment for their underlying disease. Within a days, they started to complain severe headache and diagnosed meningitis by cerebrospinal fluid analysis. Cerebrospinal fluid leukocyte counts varied from 92 to over a thound per microliter with dominance of polymorphonuclear leukocytes. Microbiologic studies revealed no organisms. All of them were free from headache within 2 days and did not suffer any neurological sequelae.

A 37Ch Visible Adaptive Optics System for Wavefront Compensation

이준호,Byung Tae Choi,Eung Cheol Kang,Hae Seog Kho,Ho Jung Cheon,Jae Il Lee,Joon Won Kim,Kyung Muk Lee,Sung Jin Kim,Young Cheol Lee,Young Il Cho 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.1

A visible adaptive system was developed to compensate for phase distortions of a visible (He-Ne) laser. The visible adaptive optics (AO) system consists of 5 subsystems: a Shack-Hartmann wavefront sensor, a deformable membrane mirror of 15 mm with 37 actuators, a high-speed tip/tilt mirror of 20 mm, a position sensor and a control & display unit. The lab-developed Shack-Hartmann sensor was experimentally shown to have a measurement accuracy of better than RMS /50 at 0.6328 μm over the maximum phase distortion that the deformable mirror could generate, i.e., approximately /4. The adaptive optics system operated the deformable mirror at 10 Hz and the tip/tilt mirror at 30 Hz, which were, respectively, closed by the Shack-Hartmann sensor and the position sensor. The closed adaptive optics system was demonstrated to compensate for time-varying wavefront aberrations of PV (Peak-to-Valley) 1.2 μm with a time frequency of 1.4 Hz. The residual RMS wavefront error was shown to be smaller than 0.014 μm, i.e., /45 at 0.6328 μm.

신호원 위치의 편향성 및 센서 이동경로에 따른 선형 LSE 알고리즘 기반 신호원 위치 추정 성능

이준호,조성우,김민철,진용기,이창훈,Lee, Joon-Ho,Cho, Seong-Woo,Kim, Min-Cheol,Jin, Yong-Ki,Lee, Chang-Hoon 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.5

In this paper, passive direction-finding localization of the emitter using noisy line-of-bearing (LOB) measurements is considered. The performance of the LOB-based emitter localization using linear LSE algorithm is given. The Dependence of the performance on bias of emitter location and sensor trajectory is illustrated using the numerical results.

지진 취약도 분석 및 보수 비용 평가

이준호,Lee, Joon-Ho 한국공간구조학회 2019 한국공간구조학회지 Vol.19 No.2

복합 슬릿-마찰 감쇠장치가 적용된 철근 콘크리트 특수 모멘트 저항골조의 내진성능 평가

이준호,김기철,김진구,Lee, Joon-Ho,Kim, Gee-Cheol,Kim, Jin-Koo 한국공간구조학회 2017 한국공간구조학회지 Vol.17 No.4

This study develops a new hybrid passive energy dissipation device for seismic rehabilitation of an existing structure. The device is composed of a friction damper combined with a steel plate with vertical slits as a hysteretic damper. Analytical model is developed for the device, and the capacity of the hybrid device to satisfy a given target performance is determined based on the ASCE/SEI 7-10 process. The effect of the device is verified by nonlinear dynamic analyses using seven earthquake records. The analysis results show that the dissipated inelastic energy is concentrated on the hybrid damper and the maximum interstory drift of the SMRF with damping system satisfies the requirement of the current code.

Kalman filter를 이용한 위치추정 알고리즘의 성능 분석

이준호,조성우,이동근,Lee, Joon-Ho,Cho, Seong-Woo,Lee, Dong-Keun 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.6

In this paper, the dependence of the Kalman filter-based emitter location algorithm on the initial estimate is investigated. Given all the LOB data, the initial estimate of the emitter location is obtained from the linear LSE algorithm with the former LOB data. Using the initial estimate, the Kalman filter algorithm is applied with the remaining LOB data to update the initial estimate. It is shown that as the number of data used in the calculation of the initial estimate increases, the accuracy of the final estimate is improved and the total computational complexity of obtaining the initial estimate and the final estimate increases. In addition, the dependence of the performance of the Kalman filter algorithm on the predefined constant is illustrated.

판상형 격간벽 시스템 건물의 반응수정계수

이준호,전용,김진구,Lee, Joon-Ho,Jeon, Yong,Kim, Jin-Koo 대한건축학회 2011 대한건축학회논문집 Vol.27 No.7

In this study seismic performance and response modification factors of rectangular reinforced concrete staggered wall system (SWS) structures were evaluated. To this end, 5, 9, 15, and 25-story SWS structural models were designed and were analyzed by pushover analysis to observe the force-displacement relationship up to failure and the location of plastic deformation. The response modification factor was computed based on the overstrength and the ductility capacities obtained from capacity envelopes. The analysis results showed that the 5- and 9-story SWS structures failed due to yielding of columns and walls located in the lower stories, whereas in the 15- and 25-story structures plastic hinges were more widely distributed throughout the stories. The response modification factors obtained by multiplying overstrength factor and ductility factor increased as the number of stories decreased.

인진쑥 추출물이 다이옥신계 TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin)에 노출된 흰쥐의 간 기능 및 지질대사에 미치는 효과

이준호,장춘뢰,필수초,황석연,Lee, Joon Ho,Zhang, Chun Lei,Bi, Shou Chao,Hwang, Seok Youn 한국영양학회 2013 Journal of Nutrition and Health Vol.46 No.3

This study was conducted in order to investigate the effects of Artemisia capillaris (AC) extract on disorders of hepatic functions and lipid metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an endocrine disrupter, using male rats (SD, five weeks old) for a period of three weeks. These 37 animals were divided into four groups. AC extract was added as 1.5% or 3% levels to basal diets, respectively. TCDD (40 ug/kg B.W) was administered by intraperitoneal injection into rats after a week from the beginning of the experiment. AC extract alleviated the increase of rat's relative liver weights induced by TCDD. Thymuses of all rats treated with TCDD were apparently shrunken by approximately 80%. Levels of white blood cells (WBC), red blood cells, hemoglobin, and hematocrits were significantly increased by treatment with TCDD, however, WBC tended to decrease by AC extract diets. In hepatic function, the elevation of glutamic oxalacetic transaminase activities by TCDD treatment was diminished by AC extract diets. Serum HDL-cholesterol levels were significantly elevated by AC extract diets. The apparent increase of triglyceride levels of rat livers induced by TCDD was significantly suppressed in the AC extract diet groups. Hepatic cytosolic catalase activities significantly decreased by treatment with TCDD showed a recovering trend by AC extract diets. In histochemical observation, the fat droplets and apoptosis of hepatocytes treated with TCDD were markedly alleviated by AC extract diets. These results indicated that AC could exert recovering effects on some disorders of hepatic functions, lipids metabolism, and antioxidant activities resulting from TCDD treatment.

A Case of Direct Invasion of the Parotid Gland by Cutaneous Squamous Cell Carcinoma

이준호,신혜경,최진수,장태정,Lee, Joon Ho,Shin, Heakyeong,Choi, Jinsu,Jang, Tae Jung Korean Cleft Palate-Craniofacial Association 2013 Archives of Craniofacial Surgery Vol.14 No.2

Cutaneous squamous cell carcinoma is the second-most common skin cancer and represents 20% of all skin cancers. Cutaneous squamous cell carcinoma often spreads to the parotid gland through lymph nodes, but, direct invasion of an adjacent organ may also occur. We present the case of 78-year-old man with ulcerated mass on the right infra-auricular area. The histopathologic finding was squamous cell carcinoma. There was no evidence of distant metastasis, but the mass was found to invade the superficial lobe of the right parotid gland. The mass was widely excised and superficial parotidectomy was performed while preserving the facial nerve. The defect was covered by primary closure. Postoperative radiotherapy was performed. At 20 months after surgery, our patient had no facial palsy, local recurrence, or metastasis. Cutaneous squamous cell carcinoma involving the parotid gland is an aggressive, rapidly advancing lesion, which if not recognized and treated early will result in high morbidity and mortality. Squamous cell carcinoma of the parotid gland has shown that patients who receive adjuvant radiotherapy have a lower recurrence rate and a higher survival rate than patients treated with surgery alone. The role of elective neck dissection remains controversial.