아동 정신건강서비스에 대한 요구도 및 실제 이용에 관한 예비적 연구

김신영,조선미,임기영,정영기,신윤미 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

Objectives : We aimed to identily the degree of perceived need and use of child mental health services, and to examine the factors associated with the perceived need and use of the child mental health services. Methods : The sample consisted of 3,477 children aged 8 to 13 years. The parents completed the sociodemographic data, the Korean version of the Child Behavior Checklist (K-CBCL), and the Korean version of DuPaul's Attention Deficit Hyperacti-vity Disorder Rating Scale (K-ARS). Results : Overall, 10% of children demonstrated the need for mental health services, and 2.36% utilized the child mental health services. All subcategoiy scores of K-CBCL and K-ARS were significantly low in the no help needed group. Factor sassociated with the actual use ofchild mental health services included social problems and thought problems. Conclusion : The demand for child mental health services is high, but only a small number of children are using mental health services. To increase actual use, it is necessary to educate and campaign for various child mental health.

낮은 상관 특성과 큰 선형 복잡도를 갖는 새로운 p-진 수열군

김영식(Young-Sik Kim),정정수(Jung-Soo Chung),노종선(Jong-Seon No),신동준(Dong-Joon Shin) 한국통신학회 2008 韓國通信學會論文誌 Vol.33 No.7C

최근에 홀수인 소수 p, n=4k, 그리고 d=((p<SUP>2k</SUP>+1)/2²에 대해서 Seo, Kim, No, Shin<SUP>[1]</SUP>이 m-sequence와 d로 decimation한 부분 수열들 사이의 상관 분포를 유도하였다. 하지만 이러한 상관 분포로부터 수열군이 자명하게 결정되지는 않는다. 본 논문에서는 우선 위의 상관 특성을 유지하는 수열군을 선택하는 방법을 제시한다. 더 나아가서 이 수열군과 동일한 상관 특성을 가지면서도 더 큰 선형 복잡도를 갖는 수열군을 새롭게 생성할 것이다. 끝으로 3진 수열의 선형 복잡도를 특정 경우에 대해서 유도하고 이 경우 원래의 수열군보다 더 큰 선형 복잡도를 가짐을 보일 것이다. For an odd prime p, n=4k, and d=((p<SUP>2k</SUP>+1)/2², Seo, Kim, No, and Shin<SUP>[1]</SUP> derived the correlation distribution of p-ary m-sequence of period pⁿ-1 and its decimated sequences by d. In this paper, two new families of p-ary sequences with family size p<SUP>2k</SUP> and maximum correlation magnitude 2√pⁿ-1 are constructed. The linear complexity of new p-ary sequences in the families are derived in the some cases and the upper and lower bounds of their linear complexity for general cases are presented.

네모나프라이드의 유효성 및 추체외로 부작용 : Haloperidol 및 Risperidone과의 자연관찰적 개방형 비교연구 A Naturalistic Open Comparative Study with Haloperidol and Risperidone

서영수,김용관,신동환,공보금,이정구,박정환,윤성환,정치영,이상경,김영훈 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

Objectives : This open prospective study was performed in order to evaluate the efficacy and extrapyramidal adverse effects of nemonapride in the schizophrenic patients, and was compared wit one of typical antipshchotics. haloperidol and one of atypical antipsychotics, risperidone. Methods : Thirty male and female schizophrenic patients(DSM-Ⅳ) were treated for 12 weeks with haloperidol(n=10), risperidone(n=10) and nemonapride(n=10). The overall efficacy was assessed at baseline, 1st week, 2nd week, 4th week, 8th week, and 12th week by the Positive and Negative Syndrome Scale for Schizophrenia(PANSS). Also the overall safety was assessed in the same time period by the Extrapyramidal Symptom Rating Scale(ESRS). Results : There were no significant differences in PANSS scores(total, positive, negative, and general psycho­pathology subscale) among haloperidol, risperidone, and nemonapride groups, Treatment responders, defined as at least 20% reduction of baseline total PANSS score, were achieved by 8 patients(80%) in haloperidol group, 10 patients(100%) in risperidone group, and 8 patients(80%) in nemonapride group. And there were no significant differences in ESRS total scores among haloperidol, risperidone, and nemonapride group. Inter-group comparison among haloperidol, risperidone and nemonapride group, as assessed by the ESRS, revealed no significant differences in the shifts to the maximum score, 9.4(±9.4), 6.2(±8.4), and 11.3(±8.1) respectively, and also revealed no significant differences in the mean time reaching the maximum score, 4.5(±4.5) week, 7.8(±4.8) week, and 4.6(±4.4) week, respectivily. Conclusion : There wee no significant differences in the efficacy and extrapyramidal adverse effects among haloperidal, rispecridone and nemonapride groups. These results suggest that nemonapride was as efficacious and safe in he treatment of schizophrenia, as well known and widely used antipsychotics, haloperidol and risperidone.

벌 자상에 의해 발생한 횡문근융해증과 급성신부전

박상곤,김영대,강지은,신정현,신병철,박차영,정춘해 朝鮮大學校 附設 醫學硏究所 2003 The Medical Journal of Chosun University Vol.28 No.2

Rhabdomyolysis is a syndrome characterized by muscle necrosis and release of intracellular muscle constituents into the circulation. The spectrum of causes is quite broad and included disorders of traumatic, metabolic, infectious and toxic origin. However, rhabdomvolvsis and acute renal failure following bee sting is rare and its pathogenesis is not well known. We experienced a case of 63-year-old man with acute renal failure and rhabdomyolysis caused by bee sting. He was stung by bee on scalp and neck. Oliguria was developed within several hours. He has fully recovered after general supportive care including fluid therapy and diuretics. This case demonstrates that rhabdomvolysis with consequent acute renal failure are able to developed by bee sting.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

재발성 류마티즘 환자에서 발작의 유발인자

주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.

뇌졸중후 연하곤란 환자의 식이 상태 비교

신용일,양충용,김헌수,강문규,주민철,길은영,권영미 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

Methicillin-내성 황색포도상구균의 각종 항균제에 대한 내성양상과 Plasmid DNA의 특성

정선식,신종희,류필열,안태휴,양동욱,김영일,이준행,김영휴 대한감염학회 1995 감염 Vol.27 No.1

광주지역의 A병원과 B병원에 입원한 환자의 각종 임상가검물로 부터 분리동정한 황색포도상구균 251주를 19종의 항균제에 대한 감수성 검사를 실시하고 내성인자를 조사하여 다음과 같은 결과를 얻었다. Oxacillin에 대한 내성빈도는 A병원에서 74.2%로 B병원의 46.1% 보다 약 30% 정도가 높았다. 또한 cephalosporine계 항균제와 aminoglycoside계 약제에 대한 내성빈도는 A 병원 분리균주에서 높은 경향을 보였으며, ampicillin(Amc), tetracycline(Tc), chloram-phenicol(Chp), ciprofloxacin(Cpfx)등의 항균제에 대한 내성빈도는 A병원와 B병원에서 분리된 균주간에 유사하였다. 그러나 fosfomycin(Fom)에 대한 내성빈도는 오히려 B병원 분리균주에서 높았다. 10가지 이상의 약제에 내성을 갖는 다제내성균의 출현율은 B병원에서 보다 A병원에서 높았다. A병원와 B병원에서 분리된 MRSA 대부분이 cefamandole(Cmdl)을 제외한 cephalosporin계 약제와 aminoglycoside제제에 대해 내성을 나타내었으며, netilmicin(Net) 과 rifampin(Rfp)에 대한 내성빈도는 A병원에서 분리된 균주에서 높았으며 Fom, Tc, Chp에 대한 내성빈도는 오히려 B병원에서 분리된 MRSA 에서 높았다. 다제내성균의 출현율은 두 병원간에 큰차이가 없었다. MRSA 의 다제내성양상은 Fom, Net, Chp 및 Rfp에 대한 내성에 따라 A병원와 B병원에 서 분리된 균주간의 차이가 관찰되었는데, A병원에서 가장 많이 나타난 내성유형은 AmcCtxCzolLmoxGmTobLcmAmkNetTcEmRfp 및 AmcCtxCzolCmdlLmoxFomGmTobLcmAmkNetTcEmRfp에 중복내성을 갖는 균주가 각각 12균주로 가장 많았으며 B병원에서 분리된 균주에서 많이보이는 내성유형은 AmcCtxCzolLmoxFomGmTobLcmAmkChpTcEm에 중복내성은 갖는 균주가 11주로 가장 많았다. 두 병원에서 분리된 균주 모두 β-lactam계 약제와 aminoglycoside계 약제간의 교차내성을 가지고 있었다. MRSA균주에서 분리한 plasmid DNA profile은 A병원와 B병원에서 분리된 균주에서 약제에 대한 다제내성양상에 따라 차이가 있었으며, A병원 분리균주에서는 108kb, B병원 분리균주에서는 2.8kb의 plasmid를 보유하는 차이가 있었다. Background: Increased isolation of methicillin-resistant Straphylococcus aureus has become one of the important problem in treating staphylococcal infections. The aim of the study was to investigate the epidemiological characteristics of antimicrobial resistance of MRSA's isolated in the Kwangju area. Methods: 251 strains of S. aureus were isolated from various specimens from A-hospital and B-hospital and there resistance patterns against 19 antimicrobial agents and plasmid profiles studied. Results: Methicillin resistance was detected in 74.2% and 46.1% of A-hospital and B-hospital isolates, respectively. Resistance to cephalosporins and aminoglycosides was more frequent in the A-hospital isolates than in the B-hospital isolates, whereas fosfomycin resistance was more frequent in the B-hospital isolates than in the A-hospital isolates. Frequency of resistance to ampicillin, tetracycline, chloramphenicol, ciprofloxacin in A-hospital isolates was similar to B-hospital isolates. Strains with multiple resistance to more than 10 drugs were more frequent in the A-hospital isolates than that in the B-hospital isolates. Among MRSA strains, resistance to netilmicin and rifampin was more frequently encountered in A-hospital isolates, while resistance to fosfomycin, tetracyclin, and chloramphenicol was more frequent in B-hospital isolates. No differences in resistance patterns against other cephalosporins and aminoglycosides were observed between the two hospitals. Fosfomycin, netilmicin, chloramphenicol and rifampin resistances were different between the hospitals in strains with multiple resistance. The most frequently observed multiple resistance patterns observed among A-hospital isolates were AmcCtxCzoILmoxGmTobLcmAmkNetTcEmRfp and AmcCtxCzolCmdlLmoxFomGmTobLcmAmkNetTcEmRfp. Among B-hospital isolates, AmcCtxCzolLmoxGmTobLcmAmkChpTcEm pattern was the most frequent. Conclusion: MRSA strains from both hospitals showed cross-resistance to β-lactams and aminoglycosides. Plasmid profiles from MRSA strains were different, according to the multiple resistance patterns. Characteristically, 108 kb plasmid was detected only in A-hospital-MRSA strains, while 2.8 kb plasmid was detected only in B-hospital-MRSA strains.

자연선택 개념의 이해에 대한 횡단적 연구

신영준,김성하,정완호 한국교원대학교 과학교육연구소 1996 청람과학교육연구논총 Vol.6 No.1

Student's misconceptions of scientific phenomena have become an issue at the science education research. Cross-sectional studies are very useful for describing the level of understanding about a particular concept held by students all over the grade. This study aimed to investigate the influence of grade level(amount of instruction) and reasoning ability about the understanding of major concepts(e. g., role of variation, change over time and origin of traits) about natural selection. The type of misconception about natural selection concept held by students across the grade levels was also investigated. Students who served as the subjects of this study were 89 of 7th grade junior high school students, 101 of 10th grade high school students at a same geographical region, 101 of college students. The students were given a battery of tests to assess reasoning ability and understanding of natural selection concept. The major results are as follows: 1. Level of understanding about natural selection with respect to grade level was very poor. Some of errant conceptions was always found in the students of all ages despite the cumulative learning of evolution, 7th grade students and 10th grade students with little science background and motivation and collegiate science majors followed the similar misconceptions about the concept of natural selection. Although the nature of the misconceptions may have changed across the grade levels, the frequency did not decease appropriately. 2. Conceptual changes of major concepts about natural selection showed no statistically significant difference in reasoning ability. But, there seems to be a correlation between a grade level and students' understanding of the concepts. 3. Cross-sectional study showed that students' common misconceptions were teleological and Lamarckian. Nevertheless, it is possible to assert that a shift in students' conceptions takes place from non-scientific categories toward (Variation) category. This will help develop the design of biology curriculum and instructions in schools.

완두 F_1세대의 조합능력 검정

정원복,오주성,황필성,황영현,신두철,한원영,김수경 동아대학교 교육대학원 2002 동아교육논총 Vol.28 No.-

완두의 이면교잡에 의한 F_1세대에 대한 조합능력을 검정한 결과는 다음과 같다. 9개 형질에 대한 GCA, SCA, RCA효과를 검정한 바 조합능력은 전 형질에서 GCA, SCA, RCA가 모두 유의하였고, 분지수·경직경·엽장·주당협수·협당립수·주당립수·100립중·주당립중은 GCA가 SCA보다 크고, 품종간 GCA효과는 고성종1호가 경직경과 100립중에서, 고성종2호가 경장·분지수·엽장에서, 김해종이 주당협수·주당립수·100립중·주당입중에서, 진해종이 협다립수에서 각각 정(+)으로 높았다. SCA효과에서 경장은 1×2(고성종1호×고성종2호)조합과 1×3(고성종1호×김해종)조합이, 분지수는 4×5(고성종3호×진해종)조합이, 경직경과 엽장은 1×3(고성종1호×김해종)조합이, 주당협수는 1×2(고성종1호×고성종2호)조합과 4×5(고성종3호×진해종)조합이, 협당립수는 1×2(고성종1호×고성종2호)조합·1×4(고성종1호×고성종3호)조합·2×3(고성종2호×김해종)조합이, 주당립수는 1×2(고성종1호×고성종2호)조합과 4×5(고성종3호×진해종)조합이, 100립중은 3×4(김해종×고성종3호)조합이, 주당립중은 1×2(고성종1호×고성종2호)조합·3×4(김해종×고성종3호)조합·4×5(고성종3호×진해종)조합이 각각 정으로 높았다. RCA효과에서 경장·엽장·주당협수·주당립중은 1×2(고성종1호×고성종2호)조합이, 주당협수·주당립수·100립중·주당립중은 2×4(고성종2호×고성종3호)조합이 각각 정으로 높았다. Five pea varieties in F₁ generation of the possible crosses among them were used to estimate the combining ability for nine characters, i. e., stem length, number of branches per plant, stem diameter, leaf length, number of pods per plant, number of seeds per pod, number of seeds per plant, 100-seed weight and seed weight per plant. Data for F₁ hybrid and parents were subjected to the analysis method proposed by Griffing. The results obtained were summarized as follows. Mean squares of general combining ability(GCA), specific combining ability(SCA) and reciprocal combining ability(RCA) were significant for all characters observed. Mean squares of GCA were higher than those of SCA and RCA in number of branches per plant, stem diameter, leaf length, number of pods per plant, number of seeds per pod, number of seeds per plant, 100-seed weight and seed weight and seed weight per plant. Variety Gimbae showed the highest GCA effect for number of pods per plant, number of seeds per plant and seed weight per plant and positively high effects of GCA were observed from variety Gosung#1 in stem diameter, 100-seed weight, and from variety Gosung#2 stem length, number of branches per plant, leaf length, from Jinhae in number of seeds per pod In SCA effects, hybrids in Gosung#1×Gosung#2 were wxhibited positively high for stem length, number of pods per plant, number of seeds per pod, number of seeds per plant and seed weight per plant, and high SCA effects for number of branches per plant, number of pods per plant, number of seeds per plant and seed weight per plant were found positively in Gosung#3×jinhae. In RCA effects, hybrids in Gosung#2×Gosung#3 were exhibited positively high for number of pods per plant, number of seeds per plant, 100-seed weight and seed weight per plant and high RCA effects for stem length, leaf length, number of pods per plant, and seed weight per plant were found positively in Gosung#1×Gosung#2.