서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

대학교 신입생의 특성에 관한 실태조사(Ⅱ) : 1995학년도 조선대학교 신입생을 대상으로 1995 chosun University Entrants

조용래,박상학,김상훈,표경식,김학렬,김양옥,김기순,박종 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

학동기 비만아동의 피부두께의 통계적 관찰

김경석,나기찬,정은경,문경래,박상기,박영봉 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

The measurements of triceps skinfold thickness, body weight and height were done in children aged 7 to 12 years(3,142 boys and 2588 girls) in Kwangju in 1992. The author also observed degree of obesity, prevalence of obesity and average value of triceps skinfold thickness. The results were summarized as follows: 1) The mean value of triceps skinfold thickness acceding to age in male was 7 years 10.5mm, 8 years 10.5mm, 9 years 10.2mm, 10 years 12.3mm, 11 years 13.8mm, 12 years 12.3mm. In the female it was 7 years 11.9mm, 8 years 11.9mm, 9 years 11.6mm, 10 years 12.6mm, 11 years 14.1mm, 12 years 13.6mm. 2) The mean value of triceps skinfold thickness acceding to age in obese male was 7 years 16.3mm, 8 years 17.3mm, 9 years 16.0mm, 10 years 19.5mm, 11 years 23.7mm, 12 years 20.1mm. In the obese female it was 7 years 17.3mm, 8 years 17.9mm, 9 years 18.4mm, 10 years 19.5mm, 11 years 21.2mm, 12 years 20.3mm.

2017년도 2학기 신라대학교 재학생의 부산인식 설문조사의 분석

김대래, 김상권, 유영명 신라대학교 부산학연구센터 2018 부산연구 Vol.16 No.1

We analyzed the questionnaires of 90 students born in Busan who are attending Silla University in the second semester of 2017. In religion, 65.6% of the students responded that they are non-religious, followed by Buddhism with 18.9%. Protestantism 13.3% and Catholicism with 2.2%. Surveyee’s fathers’ hometown was Busan(45.6%), Gyeongnam(30%), Daegu·Gyeongbuk(4.4%) and Honam·Jeju(4.4%). Mothers’ hometown was Busan(47.8%), Gyeongnam(28.9%), Daegu·Gyeongbuk(6.7%) and Honam·Jeju(4.4%). In terms of baseball games, 20% of the respondents answered that they have never watched baseball game. 23.3% of the respondents answered that they have watched it once, and 16.7% of the respondents answered that they watched baseball games twice. 20% of students never visited overseas. In the survey of favorite drinks, coffee was 32.2% the highest. Sports beverage and cola were the second most popular drinks after coffee. In the questionnaire about the representative food of Busan, pork rice soup, fish cake, wheat noodle, seed hoddok were ranked high in order. In the survey of where you want to show to your friend from outside of Busan was Gwangalli>Haeundae>Seomyun>Centum City>Lotte baseball game<Busan International Film Festival. In the questionnaire of what kind of new facilities do you want in Busan was parks>extreme stadium>bungee jumping site>dome baseball complex>hang glider>opera house. In the questionnaire about the participation in the Busan international festival in 2017, 65.6% of the students said they did not participate. And 24.4% said that they do not want to participate in the Busan International Film Festival in 2018. 41.1% responded that they have never thought participating the festival. Inquiry into the perception of Busan people’s disposition showed that they boast their successes, and think that age works as one of important social status. At the same time, the students believed that people in Busan are honest, smily and kind, and quick to greet others. Moreover, the students thought that Busan people are energetic and loyal and do not hold grudges. However, they believe that Busan people are loud, impetuous, curt, and irascible, and drive recklessly. 2017년도 2학기 신라대학교에 재학 중인 부산출신 90명의 설문조사를 분석하였다. 종교는 65.6%의 학생들이 무교라고 응답을 하였으며 그 다음으로 불교가 18.9%였다. 개신교가 13.3% 그리고 가톨릭이 2.2%였다. 아버지의 고향은 부산이 45.6%, 경남이 30%, 대구경북이 4.4% 그리고 호남제주가 4.4%였다. 어머니의 고향은 부산이 47.8%, 경남이 28.9%, 대구경북이 6.7%, 호남제주가 4.4%였다. 프로야구 관람횟수를 보면 응답자의 20%가 한 번도 본적이 없으며 1번 보러 간 학생이 23.3%, 2회 본 학생이 16.7%로 나타나고 있다. 해외여행의 경험을 묻는 설문응답을 보면 응답자 의 20%가 해외여행 경험이 없다고 하였다. 즐겨 마시는 음료는 커피가 32.2%로 가장 선호하는 음료였고 그 뒤를 스포츠음료와 콜라가 비슷한 비율로 따르고 있다. 부산사투리의 사용에는 대체로 관대하였다. 부산의 인구가 얼마나 된다고 생각하는지 적어보라는 설문에 대한 응답은 근사치인 350만명이라고 답한 학생은 12.2%에 불과하였다. 대형쇼핑몰이 입점하는 지역발전에 도움이 되는가 하는 설문에는 65.6%가 그렇다고 답하였다. 부산의 대표음식으로는 돼지국밥>어묵>밀면>씨앗호떡>파전순이었다. 외지에서 오는 친구에게 소개하고 싶은 부산의 장소는 광안리>해운대>서면>센텀시티>롯데야구>해안순환대교 순이었다. 부산에 새로 생겼으면 하는 것으로는 공원>익스트림 경기장>번지점프>돔야구장>행글라이 더>오페라하우스 순이었다. 부산국제영화제에 가본 적이 있는가에 대한 질문에는 65.6%가 없다고 응답하였다. 2018년도 국제영화제에 참여할 의사가 있는가에 대한 질문에 24.4%가 없다라고 응답하였으며, 41.1%가 생각해 보지 않았다고 하여 국제영화제에 참여한 적이 없다고 응답한 비율과 거의 같은 비율을 보였다. 부산사람들의 기질을 분석한 결과 부산사람들은 자기자랑을 많이 하고, 나이를 잘 따지며, 남의 일에 간섭을 잘하는 것으로 나타났다. 그리고 잘난체 하는 경향도 약하지만 확인되었다. 그런 반면 부산사람들은 솔직하고 웃는 얼굴을 하고 있으며 친절하고 인사를 잘 하는 것으로 대학생들은 인식하고 있었다. 아울러 부산사람들의 성격은 화끈하고 활기차며 뒤끝이 없고 의리가 있는 것으로 인식되었다. 그런 반면 부산사람들은 목소리가 크고, 성격이 급하며, 무뚝뚝하고 화를 잘 내는 것으로 인식되었으며 운전습관도 좋지 않은 것으로 인식하고 있었다.

부산경제의 현재와 미래에 대한 두 설문 : 검토와 시사

김대래,김성용,박희문,박남률 신라대학교 경제경영연구소 2008 경제경영연구 Vol.9 No.-

While the crisis argument is proliferating due to the long-term economic depression and persistent population decline, diverse new ideas for future strategy are offered. Amid such a situation, two survey results on the future of Busan economy have been reported since the beginning of the year. The First one, which is on the future of Busan and developmental strategy, is conducted among 73 former employees of Kukje Newspaper. The other one includes an analysis of the survey conducted for program production of MBC's "Busan in 10 years" series, which was broadcasted in the second half of 2006. For this report, Busan's 100 most representative enterprises and enterprisers replied to the questionnaire, distributed by Busan MBC, along with busan chamber of commerce and industry. Both reports recognize current situation of Busan as difficult and expect that the future is not so bright either. Overall, they anticipate that the future status of Busan will decline even more and suggest that Busan must seek out its own development strategy that takes a full advantage of its peculiarity as a port city. On the other hand, there are some suggestions to overcome the structural problems that caused Busan's status decline. It is forecasted that restoring and expanding the Pacific-intended specialization structure will be an important foundation to prevent thestatus decline in a long-term. This indicates that increased exchange with North Korea, Provinces of North-East China, and Russia; the construction of international division of labor area with Kyushu, Japan; and the formation of south-east industry cluster are the critical foundations of future development.

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).

해방직후 무역정책의 전개와 그 성격

김대래,최성일 新羅大學校 1996 論文集 Vol.41 No.1

The purpose of this study is to define the meaning of Trade and Trade Policy by the U.S.Army Military Government in Korea(USAMGIK) right after the Liberation. We try to find out the relationship between the building-up of Korean Economy and the Trade Policy. Usually, Trade represents the external part of a national real economy. Because of this, it takes for granted that the trade of this period have a close relation with performance of the real economy. The USAMGIK's policies were very consistent in the Agricultural and Manufacturing industry in the fact that those policies had been carrying through the USAMGIK' Will under the conflict in the real Economy. Generally speaking, it meant that Korean Economy was absorbed into the World Economic Order which had been constructed under the leadership of United States after World War Ⅱ. We also revalidate this meaning of USAMGIK' policies in this study on Trade and Trade Policies in that period. The trade, which had been controlled by government, was another form of aid, and had played a very important role in a sence that it alleviated the radical change of whole society by securing the impending shortage of goods. Moreover, vital consumption goods offered by United States as aid goods were always holding the tacit intention of market-cultivationg. Therefore, we can understand the substantial meaning of mixed structure of Trade and Aid. Hence, the Trade Policy in this period can be understood in line with other fields of USAMGIK's economic policies which tried to lead the economy of Korea to the strongly market-oriented one.

모바일 로봇의 견실제어를 위한 제네틱 알고리즘 개발

김홍래,배길호,정경규,한성현 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

This paper proposed trajectory tracking control of mobile robot. Trajectory tracking control scheme are real coding genetic-algorithm and back-propergation algorithm. Control scheme ability experience proposed simulation. Stable tracking control problem of mobile robots have been studied in recent years. These studies have guaranteed stability of controller, but the performance of transient state has not been guaranteed. In some situations, constant gain controller shows overshoots and oscillations. So we introduce better control scheme using Real coding Genetic Algorithm(RCGA) and neural network. Using RCGA, we can find proper gains in several situations and these gains are generalized by neural network. The generalization power of neural network will give proper gain in untrained situation. Performance of proposed controller will verify numerical simulations and the results show better performance than constant gain controller.

멧돼지 생식후 발생한 선모충증의 가족 내 집단발생사례

김에스더,편래현,박지한,김강호,최일,박홍훈,이용희,용태순,홍성관 대한감염학회 2003 감염과 화학요법 Vol.35 No.3

선모충증은 전 세계적으로 발생하는 기생충 인수공통감염의 한로 선모충의 유충에 감염된 육류를 덜 익혀 섭식시 발생하며 감염 초기에 설사, 복통의 증상이 나타나며 후기에 유충의 체내 이행으로 발열, 근염, 안검 부종 등이 동반된다. 확진은 근육 생검을 하여 피포 유충을 확인하는 것이고 최근에는 특이 항체를 측정하거나 유전자 검사와 같은 다양한 검사가 시도되고 있다. 저자 등은 4명의 한 가족이 야생 멧돼지를 생식한 후 선모충증의 전형적인 임상 증상 및 검사 소견을 보인 가족 내 집단발생사례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Trichinosis is a worldwide parasitic infection caused by ingesting an uncooked raw meat containing viable larvae of nematode Trichinella. Although most cases have been reported in Western countries, the incidence has decreased due to strict control of meat handlings and improved hygiene in these countries. In Korea, the first case of Trichinella spiralis was reported in a patient who ingested an uncooked badger. We have also experienced four cases of Trichinella spiralis infestation among family members who showed typical clinical manifestations and laboratory findings after ingesting raw wild swine meat, and herein report the finding.