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      • 류마티스 관절염 환자에서 발생한 연합건의 석회성 건염 - 증례보고 -

        이창훈,김성재,이승훈,구민회,이봉근,Lee, Chang-Hun,Kim, Sung-Jae,Lee, Seung-Hun,Koo, Min-Hoi,Lee, Bong-Gun 대한정형외과초음파학회 2012 대한정형외과 초음파학회지 Vol.5 No.1

        석회성 건염은 건의 부착부 주변에 발생하는 병변으로 견관절에서는 주로 극상근의 대결절 부착 부위의 근위부에 발생하는 경우가 대부분이다. 저자들은 류마티스 관절염을 가진 환자에서 발생한 상완 이두근 단두건과 오구상완근의 연합건의 석회성 건염을 초음파 검사를 통해 진단한 증례를 경험하여 보고하는 바이다. Calcific tendinitis usually occurs within the area where tendon inserts to bone. In the shoulder joints, most cases occur within the supraspinatus tendon just proximal to the greater tuberosity. We report a rare case of calcific tendinitis occurred within the conjoined tendon of coracobrachialis and short head of biceps brachii in a patient with rheumatoid arthritis, diagnosed by means of ultrasonographic evaluation.

      • 남성 불임 환자의 하복부 온도에 관한 임상적 고찰

        이창훈,조정훈,장준복,이경섭,위효선,Lee, Chang-Hoon,Cho, Jung-Hoon,Jang, Jun-Bock,Lee, Kyung-Sub,Wee, Hyo-Sun 대한한방체열의학회 2005 대한한방체열의학회지 Vol.4 No.1

        Purpose : To examine the relation between male infertility and cold hypersensitivity on lower abdomen. Methods : From 2004, 4 to 2005, 10, a total 60(infertile male 30, normal male on semen analysis 30) patients who visited the Oriental gynecological department of Conmaul Oriental Medicine hospital was selected, and their medical records were reviewed retrospectively. We compared the temperature of 3 points(CV17, CV12, CV4) of both group by DITI(Dorex, DITI-16UTI and DITI-Spectrum 9000 MB). Results and Conclusion : The general characteristics such as age, weight, height, BMI, amount and frequency of drinking and smoking of both group were not different statistically. The mean ${\Delta}T1$ between upper and lower abdomen in infertile group was higer than in normal group but they were not different statistically. The mean ${\Delta}T2$ between chest and lower abdomen was $0.46{\pm}0.41$ in infertile group, and $0.18{\pm}0.56$ in normal group, and it shows significant difference statistically. There was no significant relationship between sperm motility and ${\Delta}T1$, ${\Delta}T2$ in infertile group. In this study, we suggest that an inclination of cold hypersensitivity of lower abdomen of infertile male, but it is expressed when it is contrasted to chest of the body rather than upper abdomen.

      • SCIESCOPUSKCI등재

        흡수성 차폐막에 배양된 구개관세포의 증식양상의 비교

        이창훈,이만섭,권영혁,박준봉,허익,Lee, Chang-Hoon,Lee, Man-Sup,Kwon, Young-Hyuk,Park, Joon-Bong,Herr, Yeek 대한치주과학회 2003 Journal of Periodontal & Implant Science Vol.33 No.2

        The purpose of this study is to evaluate the phenomenon of attachment and spreading of the cultured rat calvarial cell inoculated on their surface of different kinds of biodegradable membrane which had been used on tissue regeneration on periodontal defects by using scanning electron microscope. In this experiment 30 Sprague-Dawley male rats (mean BW 150gm) were used to harvest abundant number of cell in the short period. The rats were sacrificed by decapitatioan to obtain the calvaria for bone cell culture. Calvarial cells were cultured with Dulbecco's Modified Essential Medium contained with 10% Fetal Bovine Serum under the conventional conditions. Biodegradable barrier membrane were collected with collagen type, and were divided into 3 different kind of surface such as scattered, polarized and fine-net type as their surface texture. Microcover plate which usually used for cell culture was used as control for smooth surface. All the membrane were seeded with cultured calvarial cell on their surface. The number of cell inoculated on the membrane were $1{\times}10^6$ Cells/ml. After the culture as designed time, all the membrane were washed with 0.1 M Phosphate Buffered saline and fuxed with 2.5% Glutaraldehyde. And all specimen were treated with $OsO_4$, and Tannic acid before drying the cell for coating the cell with gold. Scanning Electron Microscope was used to observation. The following results were obtained. I. During the whole period of experiment, the phenomenon of cell attachment and spreading were revealed similar pattern to compare with smooth surface culture plate and ordinary culture dish. 2. The shape of cell attachment and spreading on the surface of barrier membrane were observed no remarked difference pattern between smooth surface culture plate and ordinary culture dish. 3. The cytoplasmic process of cultured calvaria cell extent to the deep portion of barrier membrane like as their own proper shape. 4. There were no remarkable relationships between the degree of cultured cell spreading and surface structure of barrier membrane. 5. Slight starified layer of cultured calvaria cell were observed on the scattered type of resorbable membrane, Conclusively, this study thus suggest that cultured bone cell inoculated onto the biodegradable barrier membrane may have an important role of carrier for many cell which could be used as new tissue regeneration, and those tissue engeering technique may become an new method in the approach to the repair of bone defects.

      • KCI등재

        돼지감자 부위별 메탄올 추출물의 항산화 및 항당뇨 활성

        이창훈,이연리,Lee, Chang Hun,Lee, Youn Ri 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.1

        본 연구에서는 돼지감자 꽃, 잎, 뿌리가 가진 기능성 식품 소재로서의 활용도를 높이고자 다양한 생리활성을 평가하였다. 돼지감자 꽃, 잎, 뿌리의 폴리페놀 함량은 32.80 mg GAE/extract g, 43.46 mg GAE/extract g, 24.53 mg GAE/extract g으로 나타났으며, 플라보노이드 함량은 각각 15.64, 18.67, 11.65 mg GAE/extract g으로 나타났다. 돼지감자 꽃, 잎, 뿌리의 메탄올추출물의 DPPH 라디칼 소거능 활성은 각각 77.78%, 66.07%, 26.93%로 나타났으며, hydroxyl radical 소거능 활성은 각각 55.33%, 38.30%, 34.89%로 나타났다. 돼지감자 꽃, 잎, 뿌리메탄올 추출물의 아질산염 소거능을 측정한 결과, 돼지감자 추출물의 농도가 증가함에 따라 그 활성 역시 증가하는 경향으로 나타났다. 돼지감자 부위별 메탄올 추출물(5 mg/mL)의 ${\alpha}-glucosidase$ 저해활성은 꽃, 잎, 뿌리에서 각각 41.08%, 55.67%, 60.76%로 유의적인 차이를 나타났으며, ${\alpha}-amylase$ 저해활성은 꽃, 잎, 뿌리에서 각각 49.95%, 59.88%, 66.25%로 유의적인 차이를 나타내었다. This study aimed to evaluate the efficacy of the antioxidative and antidiabetic activities of the flowers, leaves, and roots of the Jerusalem artichoke (Helianthus tuberosus L.). The total polyphenol and flavonoid contents of the leaves were higher than those of the flowers and roots. However, the DPPH radical-scavenging and hydroxyl radical-scavenging activities of the flowers were higher than those of the leaves and roots. The nitrite-scavenging ability under acidic conditions was high in Jerusalem artichoke flower extracts. The ${\alpha}-glucosidase$ inhibitory activity and ${\alpha}-amylase$ inhibitory activity of a methanol extract of Jerusalem artichoke roots were about 60% (5 mg/mL concentration). Based on these experiments, it can be concluded that the flowers leaves, and roots of the Jerusalem artichoke can be used as natural preservatives. Therefore, they can be developed as functional foods, to take advantage of their antioxidant activity and abundant polyphenols. This study suggests that the whole Jerusalem artichoke, including roots, leaves, and flowers, is useful as a functional, nutritious food product.

      • KCI등재

        추나와 침술 치료로 호전된 섬유근통증후군 증례 2례

        이창훈,이명종,Lee, Chang-Hun,Lee, Myeong-Jong 척추신경추나의학회 2006 척추신경추나의학회지 Vol.1 No.1

        Objective : The Fibromyaigia Syndrome(FMS) is frequently used to call at clinic. There are not case reports on the treatment of FMS by oriental medicine. We got a effect on three patient with FMS by oriental medicine and this case is observed the clinical symptoms and scaled by VAS with chuna and acupuncture. Methods : We used to take chuna and acupunture, though classifcated by pathologic symptom and classification criteria of American College of Rheumatology. Result : Usually, most patients with FMS on the chronic stage have chronic prognosis. But symptoms of the patient on this report were improved after above treatments. Conclusion : This case showed oriental medicine enough could be applied on diseases like this syndrome as one of conservative therapies. Of course, more accurate diagnosis and research would be needed afterwards.

      • KCI등재

        방전플라즈마 소결법을 이용한 Ti<sub>2</sub>AlC Max Phase 소결체의 소결온도 변화에 따른 재료 특성 평가

        이창훈,백경래,정희상,정영근,강명창,Lee, Chang-Hun,Baek, Gyung Rae,Jung, Hee Sang,Jeong, Young-Keun,Kang, Myung Chang 한국분말야금학회 2015 한국분말재료학회지 (KPMI) Vol.22 No.3

        In this study, ternary compound Max Phase $Ti_2AlC$ material was mixed by 3D ball milling as a function of ball milling time. More than 99.5 wt% pure $Ti_2AlC$ was synthesized by using spark plasma sintering method at 1000, 1100, 1200, and $1300^{\circ}C$ for 60 min. The material characteristics of synthesized samples were examined with relative density, hardness, and electrical conductivity as a function of sintering temperature. The phase composition of bulk was identified by X-ray diffraction. On the basis of FE-SEM result, a terraced structures which consists of several laminated layers were observed. And $Ti_2AlC$ bulk material obtained a vickers hardness of 5.1 GPa at the sintering temperature of $1100^{\circ}C$.

      • 다이아스테마 해결을 위한 몇가지 테크닉에 대한 고찰

        이창훈,Changhoon Lee 대한심미치과학회 2023 Journal of the Korean Academy of Esthetic Dentistr Vol.32 No.2

        다이아스테마는 기능적인 문제가 없는 경우가 대부분이지만, 심미적인 문제까지 없는 것은 아니다. 많은 환자들에게 diastema는 심각한 심미적 결함으로 받아들여지고 있다. 이를 위한 치료로는 전통적으로 교정과 보철치료가 대세였지만, 최근은 컴포짓 레진을 이용한 치료에 대한 요구가 증가되고 있다. 비교적 시야가 좋고 접근이 쉬운 전치부이지만, 많은 술자들이 레진을 이용한 치료를 선호하지 않는다. 그 이유로는, 생각보다 까다롭고, 시간이 많이 소요되는 치료이기 때문이다. 본 글에서는 다이아스테마를 해결하기 위한 4가지 테크닉을 살펴보고 장단점에 대해서 고찰해보려고 한다. Diastema often does not cause functional problems, but it is not without aesthetic issues. It is considered a serious aesthetic flaw by many patients. Traditional orthodontic and prosthetic treatments have been the mainstream treatment, but there has been an increasing demand for treatment using composite resin. Even though anterior teeth are relatively easy to access and have good visibility, many dentists do not prefer resin-based treatments because they are more complicated and time-consuming than expected. In this article, we will examine four techniques for addressing diastema and discuss their advantages and disadvantages.

      • KCI등재

        Fault Tree를 이용한 신뢰성 분석

        이창훈,박순달,Lee, Chang-Hoon,Park, Soon-Dal 한국국방경영분석학회 1980 한국국방경영분석학회지 Vol.6 No.1

        An efficient algorithm which can be employed in obtaining the minimal cut sets of a fault tree containing repeated events is introduced. A sample fault tree illustrates this algorithm. Efficiency of an algorithm is defined as the ratio of the number of minimal cut sets to the number of cut sets determined by the algorithm. An efficiency of the proposed algorithm is compared with those of two existing algorithms : Fussell and Vesely's algorithm and Bengiamin et al. 's algorithm. The proposed algorithm is shown to be more efficient than the existing two algorithms.

      • KCI등재

        소프트웨어의 모듈평가척도와 모듈테스트 시간할당에의 응용

        이창훈,김건형,Lee Chang-Hun,Kim Geon-Hyeong 한국국방경영분석학회 1990 한국국방경영분석학회지 Vol.16 No.1

        This paper presents an allocation model of test times of software modules. An evaluation measure of modules which is based on the data flow path between modules is used at test phase. An evaluation measure is expressed by the possible path number of data flow for each module, which can be interpreted as an importance of individual module. Three criteria : module test time, module reliability, and system reliability is considered in this model. Multi-objective programming, hence, is used to solve this model.

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