http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
진로소명이 대학생들의 삶의 만족도에 미치는 영향: 사회적 지지와 계획된 우연기술의 매개효과
정우희,김혜원 한국청소년학회 2017 청소년학연구 Vol.24 No.2
The purpose of this study was to examine the relationship between career calling and life satisfaction among college students, and to identify the mediating effects of social support and planned happenstance skills. A total of 341 students was recruited from colleges in Seoul, Gyeonggi, and Chungcheong Province. They completed the questionnaire package, including career calling, social support, planned happenstance skills, and life satisfaction. The relationship among four variables was examined through correlation analysis. Based on these results, the relationships including mediating effects were verified by structural equations. The results of this study were as follows. First, career calling had positive effects on social support, planned happenstance skills, and life satisfaction. Second, career calling, social support, and planned happenstance skills had positive effects on life satisfaction. Third, social support and planned happenstance skills played a partial mediating role in the relation between career calling and life satisfaction. Based on these results, the necessity of career counseling from the point of view of career calling to increase the satisfaction of life was discussed, and directions for future research were suggested. 본 연구에서는 최근 주요 진로 관련 가치 중 하나로 주목 받고 있는 진로소명에 초점을 두고 진로소명이 대학생들의 삶의 만족도에 어떤 영향을 주고, 이 영향에 사회적 지지와 계획된 우연기술이 유의한 매개효과를 갖는지를 규명하고자 하였다. 이를 위하여 서울, 경기, 충청권 대학생 341명을 대상으로 진로소명, 사회적 지지, 계획된 우연기술, 삶의 만족도를 포함하는 설문조사를 실시하였다. 네 변인간의 관계를 상관분석을 통해 검토하였고, 그 결과를 토대로 진로소명과 삶의 만족도의 관계 및 이에 대한 사회적 지지와 계획된 우연기술의 매개효과를 구조방정식을 통해 검증하였다. 연구 결과 첫째, 진로소명은 사회적 지지, 계획된 우연기술, 삶의 만족도와 정적인 상관관계가 있었다. 둘째, 진로소명과 사회적 지지, 계획된 우연기술은 모두 삶의 만족도에 정적인 영향을 미쳤다. 셋째, 진로소명과 삶의 만족도 간의 관계에 사회적 지지와 계획된 우연기술이 부분매개효과를 갖는 것으로 나타났다. 연구결과를 바탕으로 대학생들의 삶의 만족도를 높이기 위한 진로소명 관점의 진로상담 필요성을 논의하였고, 연구의 의의, 제한점 및 향후 연구를 위한 방향성을 제언하였다.
In vitro and in vivo Biological Responses of Proton Irradiation from MC-50 Cyclotron
정우희,엄현수,정권,박혜란,조성기 한국방사선산업학회 2012 방사선산업학회지 Vol.6 No.3
In this study, we investigated the biological damage and stress responses induced byion beam (proton beam) irradiation as a basis for the development of protective measures againstspace radiation. We examined the biological effects of proton beam produced by MC-50 cyclotronat KIRAMS on the cultured cells and mice. The proton beam energy used in this study was 34.9MeV and the absorption dose rate for cells and mice were 0.509 Gy sec-1 and 0.65 Gy sec-1, respectively. The cell survival rates measured by plating efficiency showed the different sensitivity anddose-relationship between CHO cells and Balb/3T3 cells. HGPRT gene mutation frequency in Balb/3T3 was 15×10-6 Gy-1, which was similar to the reported value of X-ray. When stress signalingproteins were examined in Balb/3T3 cells, IκB-α decreased markedly whereas p53, phospho-p53,and Rb increased after proton beam irradiation, which implied that the stress signaling pathwayswere activated by proton beam irradiation. In addition, cellular senescence was induced in IMR-90 cells. In the experiments with C57BL/6 mouse, the immune cells (white blood cells, lymphocytes)in the peripheral blood were greatly reduced following proton beam irradiation whereas red bloodcells and platelets showed relatively little change. These results can be utilized as basic data forstudying the biological effects of proton beam using MC-50 cyclotron with respect to proton therapyresearch as well as space radiation research.
정우희,구자승,김민정,김은경 한국유방암학회 2010 Journal of breast cancer Vol.13 No.2
Purpose: Our purpose was to identify the factors in a breast core needle biopsy (CNB) of atypical ductal hyperplasia (ADH) that are predictive for carcinoma in the subsequent excision specimens. Methods: We performed a retrospective pathologic review of 50 cases that were diagnosed as ADH via the CNB and that had the corresponding excision specimens. Results: The size of the largest ADH foci in the CNBs was 0.8±0.6 mm (mean±SD) for benign proliferative disease (BPD, n=12), 1.0±0.5 mm (mean±SD) for ADH (n=9) and 1.3±0.8 mm (mean±SD) for malignant lesions (n=29) in excision specimens (p=0.105). Among the 30 cases showing stromal alterations around the ducts with ADH in the CNBs, 9 cases (30.0%) were BPD or ADH and 21 cases (70.0%) were malignant lesions in the excision specimens (p=0.004). Conclusion: As the stromal alterations around the ADH were noted in the CNB, there was an increased likelihood that more advanced lesions would be identified in the surgical excision specimens.