부산지역 무균성 뇌막염 원인 바이러스의 분리 및 동정 : 1998년을 중심으로

김영희,정영기,김기순,지영미,윤재득,김병준,구평태,민상기,정구영,김만수,조경순 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6, 25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing anti body test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.

정신분열병 환자들의 自己灣入에 관한 예비 연구

박성봉,김영미,전성일,이기철,김영훈,정영조,이영렬,이정호,최영민 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.6

목 적 : 정 신분열병 환자의 자기만입 정도에 영향을 미치는 인구학적 변인들 및 질병연관 변인들을 규명해 보고자 하였다. 또한. 환자들의 자기만입과 병식 사이의 연관성. 자기만입과 자존심 사이의 연관성을 알아보고자 하였다. 방 법 : 정신과 의사가 병록지와 면담을 통하여 대상 정신분열병 환자들의 인구학적 변인들 및 질병연관 변인들에 관한 자료를 얻고 환자들의 병식 정도를 평가한 후, 환자들로 하여금 자기보고형의 자기만입 척도와 자존심 척도를 시행하게 하였다. 총 111명의 환자가 연구대상으로 선택되었다. 결과: . 1) 여자가 남자보다 유의하게 높은 자기만입 척도 점수를 나타내었다 2) 질병연관 변인들 중 하위집단 사이에 자기만입 척도 점수의 유의한 차이를 보이는 변은 없었다. 3) 자기만입 척도 점수와 병식 점수 사이에 유의한 상관관계가 없었다. 4) 자기만입 척도 점수와 자존심 척도 점수 사이에 유의한 역상관 관계를 보였다. 결 론 : 본 예비 연구의 결과로 보아 정신분열 병 환자의 병식이 부족한 상태에서도 자기만입이 진행될 수 있으며. 자기만입이 심할수록 환자의 자존심이 저하되는 것으로 생각된다. 또한 여자 환자들이 남자 환자들보다 자기만입에 더 취약한 것으로 생각된다. 따라서 정신분열 병 환자의 이해와 치료를 위하여 자기만입에 관한 지속적인 연구가 필요할 것으로 생각된다. objective : This study was conducted to identify demographic variables and illness related variables which may affect the severity of self-engulfment in the patients with schizophrenia. We also studied the relationship between self-engulfment and insight, and the relationship between self-engulfment and self-esteem. Methods : Data on demographic variables and illness related variables for the subjects were gathered from hospital records and clinical interviews by the psychiatrists. Degree of insight for the subjects was assessed through clinical interviews by the psychiatrists. Degree of self-engulfment and self-esteem for the subjects was assessed from the self-engulfment scale and the self-esteem scale respectively. A total of 111 patients with schizophrenia were selected for statistical analysis. Results 1) The females exhibited significantly higher scores than the males on the self-engulfment scale. 2) There was no illness related variable, which exhibited a significant difference among subgroups on the self-engulfment scale. 3) There was no significant correlation between the self-engulfment scores and the insight 4) There was a significantly inverse correlation between the self-engulfment scores and the self-esteem scores. Conclusion : The results of this preliminary study suggest that self-engulfment may develop despite lack of insight and that there was inverse relationship between self-engulfment and self-esteem in the patients with schizophrenia. It also suggests that females are more subject to self-engulfment than males. So, authors suggest that it is valuable to do further studies of self-engulfment in the patients with schizophrenia.

혈청 감마지티(gamma glutamyl transferase)치와 대사증후군 연관성

장미,유병욱,조용진,오정은,홍성호,조주연 순천향대학교 의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

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크세논 램프에 노출된 복합레진의 색조변화

조영곤,서정일,김수미,정진호,이영곤 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.3

The purpose of this study was to evaluate the color changes of the composite resin resulting from xenon lamp exposure in different environments. Composite resin (Z 250 ; shade A1, A2, A3.5 and A4) were applied in a cylindrical metal mold. Seventy five specimens according to environments of exposure were made as follows; Group Ⅰ : aluminum foiling of the specimens in the air at 37℃ for 1 day and 7 days. Group Ⅱ : exposure of xenon lamp to the specimens in the air at 37℃ for 1 day and 7 days. Group Ⅲ : exposure of xenon lamp to the specimens in distilled water at 37℃ for 1 day and 7 days. The color characteristics (L^*, a^*, b^*) of the specimens before and after exposure of xenon lamp were measured by spectrophotometer and the total color differences (ΔE^*) were computed. The results obtained were as follows: 1. In all groups except A1 shade of group Ⅲ, the ΔE^* values presented below 2.0, and group Ⅲ showed the highest ΔE^* values followed by group Ⅱ and group Ⅰ in a decreasing order(p<0.05). 2. In all shades and groups, the more the exposure time of xenon lamp and the lighter the shade were, the higher the tendency for discoloration(p<0.05). 3. The composite resins which was exposed to xenon lamp in the distilled water was more discolored than those in the air (p<0.05). 4. The major changes of composite resins which were exposed to xenon lamp in the air were an increase in yellowness through a positive shift of the b^* value, and those in the distilled water were an increase in darkness and yellowness through a negative shift of the L^* value and a positive shift of the b^* value.

상아질에 대한 자가 산부식 접착제의 전단결합강도와 SEM 분석 비교

조영곤,노기선,김수미,이영곤,정진호,기영재 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.3

The purpose of this study was to compare shear bond strength and interfacial pattern of composite bonded to dentin using self-etching adhesive systems. Sixty extracted human molars with exposed occlusal dentin were divided into four groups and bonded with four adhesives and composites: Single Bond/Filtek Z 250(SB), Tyrian SPE-One-Step Plus/Aelitefil(TY), Prompt L-Lpop/Filtek Z 250(LP), and one-Up Bond F/Palfique Toughwell(OU). The results of this study were as follows; 1. Shear bond strength for OU was significantly lowet than that of other groups(p<0.05). No significant difference was founded among SB, TY, and LP. 2. Failure modes to dentin showed adhesive and mixed for SB, TY, and LP, but them for OUT showed adhesive in all spceimens. 3. Dentin-resin interface showed close adaptation for SB, TY, and LP, but it showed gap for OU. 4. The hybrid layers for TY, LP, OU were thinner than that of SB. Adhesive layers were observed between composite and hybrid layer, which were 5 ㎛ thick for TY and 10 ㎛ thick for OU.

치질에 접착된 자가 산부식 프라이머와 자가 산부식 접착제의 형태학적 양상

조영곤,이석종,정진호,이영곤,김수미 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.1

The purpose of this study was to compare in vitro interfacial relationship bonded with three self-etching primer adhesives and one self-etching adhesive. Class I cavity preparations were prepared on twenty extracted human molars. Prepared teeth were divided into four groups and restored with four adhesives and composites: Clearfil SE Bond/Clearfil^™ AP-X (SE), UniFil Bond/UniFil® F (UF), FL Bond/Filtek^™ Z 250 (FL) and Prompt L-Pop/Filtek^™ Z 250 (LP) After storing in distilled water of room temperature for 24 hours, the specimens were vertically sectioned and decalcfied, Morphological pattern between the enamel/dentin and adhesives were observed under SEM. The results of this study were as follows; 1. They showed close adaptation between enamel and SE, UF and FL except for LP. 2. The hybrid layer in dentin was 2 ㎛ thick in SE, 1.5 ㎛ thick in UF, and 0.4 ㎛ in both FL and LP. So, the hybrid layers of SE and UF were slightly thicker than that of FL and LP. 3. The lengths and diameters of resin tages in UF and FL were similar, but those of LP were slightly shorter and slenderer than those of SE. 4. The resin tags were long rod shape in SE, and funnel shape in other groups. Within the limitations of this study, it was concluded that self-etching primer adhesives showed close adaptation on enamel. In addition, the thickness of hybrid layer ranged from 0.4-1.5 ㎛ between adhesives and dentin. The resin tags were long rod or funnel shape, and dimension of them was similar or different among adhesives.

Ranitidine, Sucralfate, Bismuth Subcitrate 복합제의 흰쥐 위궤양에 대한 치료효과

조태순,조광재,주일로,이선미,유영효 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.1

Gastric ulcer disease results when there is an imbalance between aggressive factors(acid secretion) and protective factors(mucosal defence). H_2-receptor antagonists are the most frequently used agents for treatment of gastric ulcer disease. However, use of these products should be determined by potential for adverse effects, drug interactions and cost. Ranitidine, H_2 - receptor antagonist, competitively block the H_Z-receptor on the parietal cell, causing inhibition of gastric acid secretion. Sucralfate and bismuth subcitrate coat ulcer craters and then enhance mucosal defence. Bismuth subcitrate also causes detachment of Helicobacter pylori from the gastric epithelium with subsequent lysis of the bacteria. To estimate effects of the mixture of ranitidine 20mg/kg, bismuth subcitrate 40mg/kg and sucralfate 120mg/kg on aspirin - HCl induced gastric ulcer in rats, gastric ulceration, pH, gastric secretion, free and total acidity, pepsin activity, gastric mucosal hemorrhage were investigated. Results obtained were as follow : 1) The mixture showed remarkable suppression of gastric ulceration, pH, gastric secretion, free and total acidity, pepsin activity, gastric mucosal hemorrhage compared with ranitidine alone. 2) With elapse of time, the mixture showed more increasing inhibitory effects on gastric ulceration, pH, gastric secretion, pepsin activity, gastric mucosal hemorrhage than sucralfate and bismuth subcitrate.

F.Chopin의 24Preludes Op.28에 관한 小考 : focusing on the interpretation of its Performance 그 演奏 解釋上의 科題를 中心으로

趙英美 西原大學校 1987 西原大學 論文集 Vol.20 No.-

Twenty-fpur Preludes Op.28 by F.Chopin are one of the representative pieces in his Majorca period. He, having already had an interst in large-scale and splendid style since over ten years before them, showed a lot of signs that he had trouble composing these miniatures. He settled the trouble by taking their structure from the classical form of serial musical piece. Technically, the tempo of pendulum movement ranges from the beginning to the end of the Preludes, which consist of three parts in large. Twelve, the very half of twenty-four pieces, are commonly framed at intervals of two degrees of melody. It is also founded that twenty-four Preludes display his various musical technuques of Nocturn, Barcarole, Mazurka, Etude and Impromptus. Besides, F. Chopin presents his inward and poetic spirit with his unique usage of piano, that is, the expression through the effective use of pedal, slur and dynamics, in the Preludes. Such a small piece as these Preludes need a concrete research on it before performance or study all the more because it holds a great deal of inwardness. So, as we research into twenty-four Preludes Op. 28 which express a poetic spirit in contrast and ambiguousness, we are convinced again that the freedom of a performer does not begin until the concrete approach to the pieces,

모범학생과 비행학생의 가정환경 비교연구 : 서울시내 일부 주·야간 고등학교를 중심으로

조결자,조미영,김윤희 慶熙大學校 1986 論文集 Vol.15 No.-

Today, adolescence and student's delinquencies are increasing gradually in the social instability confusion associated with rapid social change. Therefore this research was attemped to help to constructing the bright and sound welfare society, and to contributing the basic data for performing expanding roles as a nursing practitioner and the more contributing to develop the nursing science through counselling and treating their delinquent and criminal behavior. The duration of study was from Sep. 20 to Oct. 20, 1985. The number of all students participated in this study were 891(model 182, delinquent Student 351). The results that analyze and compare the differenciation between two groups in their family environmental factors were as the following. One tool of the study used for classifying the type and the seventy of delinquent behaviros was the 63 items developed by Clark and Wenningor, and then we reconstructed and used only 43 items(Cronbach's α=0.8521) among them. And we used the other questionnaire constructed of 32 items(Cronbach's α=0.912) after correct and modify several times by 3 researchers for family environmental factors. The gathered datas were took statistics using SPSS m accordance with the purpose of study and we came to results like these; 1. General characteristics of subjects. In the distribution of day and night school, girls and boys, day schools(49.9%) and night schools(50.1%) are similar, the number of girls (63.0%) were much more than boys. In the distribution of model and problem students, problem students (65.8%) was much more than the model. In the age and the order of birth, group of 17 years old(36.8%) was extremely much and the middle born(38.7%) too. 2. The comparison of general characteristics between day and night schools model and problem students. Generally, the night school students' age (17.2∼17.3 yrs.) was more than the day school students' (16.2∼16.5 yrs.) In the comparison of class years, problem students were more as the grade is higher. In the sex, day school have more problem behaviors in boy's school, night school have more in girl's school and in the order of birth, the middle, the last born and the only son(or girl) have more problem behaviors. 3. The content and frequency of delinquent behaviors in problem students Among contents and frequencies of delinquent behaviors extremely much behaviors were "drinking"(20.2%), the next behaviors were "smoking" and "destructiveness"(each other 15.5%) and the next was "resistance to his parent"(15.1%). Thirteen behaviors, excepted "having the weapon" "experienced the premarital sexual relation" have much more than night school students. The percentages of students experienced the delinquent behavior in all subjects were 74.7%, frequencies of delinquent behavior in problem students were for one student from one to eleven times. Their delinquent behavior of each person was commonly 1.9 times. 4. Comparison of the family environment between model and problem students 1) The physical family environment In comparison of the physical family environment, there are certainly significant differentiations between model and problem group. In the type of a residence, the group of no-residence have, in the level of parent's age, the group of the prime manhood have, in his parent's religion, the group of no-religion have, and the group of having not a father or a mother have higher rates of delinquent behaviors more than model students, and the lower are the level of his parent's educational background, the more severve are delinquent behavior of problem students. 2) The psychological family environment ① Comparison of the relation between the attitude of the parent's fostering and the students attitude to his parent. The more positive was the attitude of the parent's fostering for his children, the more positive was the student's attitude to his parents. The more positive was the attitude of the mother's fostering for his children, the more positive are the student's attitude to his father. But in the father's fostering attitude to his children was the better, the student's attitude to has mother was not just better. ② parent's fostering attitude for his children In comparison of the differentiation between the mother's attitude for his children and children's attitudes to his mother and father in model and problem students, model students had more positive feeling for his parent than problem students. 5. Comparison of the relation among specific behaviors(smoking, drinking, using of the dependent drug) 1) physical environment In no-owner house groups and no-religion groups in parents of physical environmental factors. In comparison of the relation between the specific behavior and physical family environmental fact the group that their parent had no-owner house, their mother have no-religion, and living seperately from parent at present was much more smoking, drinking, and using of the dependent drug. 2) In comparison of the relation between specific behaviors and psychological family environmental factors, "the no-smoking" "the trust for his children" group was higher level in parent's attitudes on "the approval for his children" and "the respect of his children's opinion" than the past now experienced smoking group. In drinking, no-drinking group is higher level in father s attitude on "the trust for his children" "the approval for his children" the respect of his children's opinion" and "the consideration for his children" than the past and now experienced drinking group. In using of the dependent drug, there are no different between the no-using group and the using group. As the above result, we can find facts that if their parent's educational background and socio-economical level are lower and students don't live with their parents or their parents died already they have more delinquent behaviors. We can find the fact that if the student lives in home where communicate well with his parent and they have satisfactory family life together with trust, such student have lower frequency of delinquent behaviors. We understand and recongnize that the problem children are maked by problem parent and problem family, so our community have to do their best to plan and to implement the best issue for prevention of delinquent adolescents.

레진전색제의 마모저항성에 대한 평가

김수미,한세희,조영곤 대한치과보존학회 2007 Restorative Dentistry & Endodontics Vol.32 No.3

이 연구는 강화형 미세입자 복합레진인 Micronew에 BisCover 레진전색제를 적용한 후 칫솔마모시험을 시행하여 복합레진 표면의 조도와 현미경적 변화를 비교함으로써 레진전색제를 복합레진 표면에 재적용할 시기를 알아보고자 하였다. 분리 가능한 알루미늄 판과 복합레진을 이용하여 8×3×2 mm크기의 복합레전 시편 200개를 제작하였다 복합레진 시편의 양쪽표면을Sof-Lex disc로 거친 입자에서 증간 입자까지 마무리한 후 실온의 증류수에 34시간 동안 보관하였다. 시편은 disc로 마무리만 시행한 F군 (n=10)과 마무리 후 레진전색제인 BisCover를 적용한 B군 (n=190)으로 분류하였다. B군은 다시 칫솔질을 가하지 않은 B-IM 군 (n=10)과 칫솔질을 가한 군 (n=180, B-1군에서 B-l8군)으로 분류하였다. 칫솔질을 가한 군은 칫솔마모검사기의 수조에 페리오 치약과 증류수를 무게 비 50 : 50으로 혼합하여 부은 다음 홈이 파진 알루미늄 블록에 각 군의 시편을 위치시키고 칫솔을 고정장치에 부착하여 전, 후 왕복운동을 가하여 칫솔질을 가하였다. 칫솔질은 B-1군에서 B-18군 까지 각각 900회씩 증가시켜 16,200회까지 시행하였다. 표면조도측정기를 사용하여 각 군의 복합레진 표면의 평균 표면조도 값 (Ra)을 산출한 후 통계적으로 분석하였고. 주사전자현미경하에서 각군의 대표적인 시편 1개를 관찰하여 다음과 같은 결과를 얻었다. 1. F군의 Ra는 0.898±0.145 ㎛, B-IM 군의 Ra는 0.289±0.142 ㎛를 나타냈으며, B-1군에서 B-18군까지의 Ra는 점차적으로 증가하여 B-1 군에서 0.299±0.48 ㎛, B-18군에서 0.642 ± 0.313 ㎛까지 나타났다. 2. Ra 최종 군집중심은 군집 1 (B-IM∼B-7)에서 0.361 ㎛, 군집 2 (B-8∼B-14)에서 0.511 ㎛, 군집 3 (B-15∼B18)에서 0.624 ㎛를 나타내어 각 군집의 Ra 최종 군집중심 간에 통계학적으로 유의한 차이를 나타내었다. (F=49.705, p=0.000) 3. B-IM군의 Ra 증감율은 F군에 비해 210.72%감소되었으며, B-8군과 B-15군의 Ra 증감율은 B-IM군에 비해 각각 35.49%와 51.35% 증가되었다. 4. FE-SSM 관찰에서 B-IM 군은 매우 평활한 복합레진 표면을 나타내었고, B-8군은 전체적으로 평활한 복합레진 표면을 보였지만 표면에 수직으로 아주 얕은 흠집을 나타내었다. B-15군은 복합레진 표면의 중앙에서 B-8군보다 더 넓고 불규칙 한 수직의 흠집을 나타내었고, B-18군은 복합레진 표면 전체에 넓은 흠집을 나타내었다. The purpose of this study was to evaluate the abrasion resistance of surface penetrating sealant which was applied on a composite resin restoration and to provide proper time to reapply sealant on composite resin surface. Two hundred rectangular specimens, sized 8×3×2 mm, were made of Micronew (Bisco, Inc., Schaumburg, IL, U.S.A) and divided into two groups F group (n = 10) was finished with coarse and medium grit of Sof-Lex discs and BisCoverwas applied B group (n = 190) after finishing with discs. B group was again subdivided into nineteen subgroups. From B-1 group to B-18 group were subjected to toothbrush abrasion test using a distilled water-dentifrice slurry and toothbrush heads. B-IM group was not subjected to toothbrush abrasion test. Average surface roughness (Ra) of each group was calculated using a surface roughness tester (Surfcorder MSE-1700: Kosaka Laboratory Ltd., Tokyo, Japan). A representative specimen of each group was examined by FE-SEM (S-4700: Hitachi High Technologies Co., Tokyo, Japan). The data were analysed using cluster analysis, paired t-test, and repeated measure ANOVA. The results of this study were as follows; 1. Ra of F group was 0.898±0.145 ㎛ and B-IM group was 0.289±0.142 ㎛. Ra became higher from B-1 group (0.299±0.48 ㎛) to B-18 group (0.642±0.313 ㎛). 2. Final cluster center of Ra was 0.361 ㎛ in cluster 1 (B-IM∼13-7), 0.511 ㎛ in cluster 2 (B-8 B-14) and 0.624 ㎛ in cluster 3 (B-15∼B-18). There were significant difference among Ra of three clusters. 3. Ra of B-IM group was decreased 210.72% than Ra of F group. Ra of B-8 group and B-15 group was increased 35.49% and 51.35% respectively than Ra of B-IM group. 4. On FE-SEM, B-IM group showed the smoothest resin surface. B-8 group and B-15 group showed vertically shallow scratches, and. wide and irregular vertical scratches on composite resin surface respectively. Within a limitation of this study, finished resin surface will be again smooth and glazy if BisCover would be reapplied within 8 to 14 months after applying to resin surface. [J Kor Acad Cons Dent 32(3):180-190, 2007]