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      • 노인의 영적 간호요구

        최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

        This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

      • SCOPUSKCI등재

        Lysophosphatidic acid increases mesangial cell proliferation in models of diabetic nephropathy via Rac1/MAPK/KLF5 signaling

        Kim, Donghee,Li, Hui Ying,Lee, Jong Han,Oh, Yoon Sin,Jun, Hee-Sook Nature Publishing Group UK 2019 Experimental and molecular medicine Vol.51 No.2

        <▼1><P>Mesangial cell proliferation has been identified as a major factor contributing to glomerulosclerosis, which is a typical symptom of diabetic nephropathy (DN). Lysophosphatidic acid (LPA) levels are increased in the glomerulus of the kidney in diabetic mice. LPA is a critical regulator that induces mesangial cell proliferation; however, its effect and molecular mechanisms remain unknown. The proportion of α-SMA<SUP>+</SUP>/PCNA<SUP>+</SUP> cells was increased in the kidney cortex of <I>db/db</I> mice compared with control mice. Treatment with LPA concomitantly increased the proliferation of mouse mesangial cells (SV40 MES13) and the expression of cyclin D1 and CDK4. On the other hand, the expression of p27<SUP>Kip1</SUP> was decreased. The expression of Krüppel-like factor 5 (KLF5) was upregulated in the kidney cortex of <I>db/db</I> mice and LPA-treated SV40 MES13 cells. RNAi-mediated silencing of KLF5 reversed these effects and inhibited the proliferation of LPA-treated cells. Mitogen-activated protein kinases (MAPKs) were activated, and the expression of early growth response 1 (Egr1) was subsequently increased in LPA-treated SV40 MES13 cells and the kidney cortex of <I>db/db</I> mice. Moreover, LPA significantly increased the activity of the Ras-related C3 botulinum toxin substrate (Rac1) GTPase in SV40 MES13 cells, and the dominant-negative form of Rac1 partially inhibited the phosphorylation of p38 and upregulation of Egr1 and KLF5 induced by LPA. LPA-induced hyperproliferation was attenuated by the inhibition of Rac1 activity. Based on these results, the Rac1/MAPK/KLF5 signaling pathway was one of the mechanisms by which LPA induced mesangial cell proliferation in DN models.</P></▼1><▼2><P><B>Kidney disease: Mechanisms of diabetes-related damage</B></P><P>A potent molecular mediator of diabetic kidney disease induces its pathogenic effects via proteins that could be targeted with future drug therapies. Yoon Sin Oh
from Eulji University in Seongnam-si and Hee-Sook Jun from Gachon University in Incheon, both in South Korea, and colleagues treated certain cells found in the kidney’s glomerulus, the organ’s filtering unit, with a signaling molecule called lysophosphatidic acid (LPA) that is elevated in the blood of diabetic mice. They showed that LPA stimulated cellular proliferation and boosted the expression of proteins involved in regulating the cell cycle and a multipurpose signaling pathway. They then inhibited the activity of these proteins to prevent the kidney cells’ hyperproliferation, both in cell culture and in diabetic mice. The results highlight the potential of blocking mediators of LPA signaling to treat kidney-related complications of diabetes.</P></▼2>

      • 노인요양시설 거주노인의 생활만족도

        윤숙희 인제대학교 2010 仁濟論叢 Vol.25 No.1

        This study aims at providing high quality of nursing care to improve life satisfaction for the elderly in nursing home. A sample consisted of 92 older residence from 6 nursing home located in Busan and GyeongNam province, The data were collected during Aug, 2009, A self-administered questionnaire was used to assess socio-demographics, life satisfaction, The total score of life satisfaction of the elderly in nursing home was 13.75(±5.38). The general characteristics related to life satisfaction were gender, age, spouse, monthly allowance, education, health condition, length of stay in nursing home, The development of supportive program for increasing life satisfaction of the elderly is needed in nursing home.

      • KCI등재후보
      • 뇌졸중 환자 가족의 돌봄의 경험 : 현상학적 연구

        윤숙희 인제대학교 1995 仁濟論叢 Vol.11 No.2

        The concept of the family burden for helping patients in the hospital as well as in the home setting has been raised as a nursing issue recently Those who survive stroke are discharged to home disabled and the responsibility for providing adequate care to the patient has fallen primarily on family members. Therefore this study using phenomenologic approach was carried out to explore and explain the experiences of family caregivers of stroke. The informants of the study were 5 family caregivers caring for the patients with stroke at hospitals or their homes. The study was conducted from Novembers 1995 through January, 1996. Data were collected through in-depth interviews, telephone interviews and narrative data. Data collection and analysis were conducted concurrently. Analysis method of data was Giorgic method. According to the results, caregiving has been associated with emotional crisis, physical discomfort, guilty feeling, anxiety, feeling of social isolation and depression. This study offers better understanding on the caregiving experiences and may facilitate more appropriate interventive strategies.

      • KCI등재

        간호사의 직무스트레스와 노인에 대한 지식, 태도 및 케어실천행위

        윤숙희 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.4

        Purpose: This study was to examine the relation of nurses' job stress and knowledge, attitude and care behavior for elderly patient in hospitals. Method: One hundred ninety one nurses caring the elderly patients in hospitals in Ilsan, Busan and Gyeongsangnam-do were subjects. The data was collected between Sept. 21 and 31, 2009. Data was analyzed using t-test, ANOVA, Pearson correlation with SPSS/Win 17.0 and the fitness of pathway models with AMOS 5.0. Results: The mean scores of job stress and knowledge were in middle range, and attitude and care behavior were in a little higher range. The fitness of hypothetical model was excellent. Job stress had direct effects on attitude and care behavior, knowledge had direct effect on attitude and attitude had direct effect on care behavior. But the pathways related to job stress and attitude and job stress and care behavior were not significant. In modified model deleted the pathway between job stress and attitude, the pathway related to job stress and behavior also was not significant. Conclusion: Education related to the elderly for nurses to improve care behavior is needed continuously.

      • RISS 인기논문 KCI등재

        임상간호사의 직무스트레스와 우울 : 한국인 직무스트레스 측정도구를 이용하여

        윤숙희 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.3

        Purpose: The purpose of this study was to examine the level of occupational stress and depression in clinical nurses and to investigate the effects of subscales of occupational stress on depression. Method: A sample consisted of 202 nurses from 6 hospitals located in Busan and GyeongNam province. The data were collected from November 2008 to march 2009. A self-administered questionnaire was used to assess socio-demographics, job characteristics, depression measured by Korean CES-D, and occupational stress assessed by KOSS. Result: The total score of occupational stress in clinical nurses was within bottom 25%, but the scores of 'Difficult physical environment', 'High job demand', 'Inadequate social support', 'Organizational injustice' were within top 50%. The 8 subscales of occupational stress had significantly effects on clinical nurses' depression after controlling for age, marital status, type of hospital, current position. Conclusion: The administration of employee assistance program for management occupational stress is important for decreasing depression in clinical nurses.

      • 대학생의 기부행동과 기부인식

        고희범, 김윤식, 장동명, 이희숙 충북대학교 생활과학연구소 2013 생활과학연구논총 Vol.17 No.2

        The purpose of this study was to find charity act and awareness of university. Questionnaire survey was conducted from 11 July to 18 July 2011. And 300 university students who were attending universities in Cheongju area. Major findings as follows. First, most university students(86.1%) had experienced to donate money instead of their time or talents. And they donate to mostly religious institutes. These result implied that university students would be better time or talent donation rather than money, since they had no earned income yet. For this, it would be important that university headquarters or social institutes make opportunities to donate time or talents for university students. Second, it was found that why university students did not donate during university period. That is, first, university students did not believe charity institutes, second, university students have not been asked to donate, and university students thought that they had no money enough to donate. These results implied that charity institutions should have clear management system, and university students would be better time or talent donation rather than money again. Third, it was found that charity awareness of university students was more likely to be positive, and that the students who had donation experience showed more positive charity awareness than the counter part. This result implied to expecially parents that it is important socialization of children's donation behaviors and awareness.

      • 스포츠이벤트의 경제적 효과와 발전 방향

        남희은,김윤숙,이근모 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

        Although sports events have so many extend effect on the field of politics, diplomatic, social, culture, and economic, especially the economic effect is very important. In this view, this study was researched that the economic effect through sports events and development direction to induce a long term effects. The economic effect through the sports events are as follows; 1. Direct effect of economic : construction, arrangement of the lower part and traffic, etc. 2. Effect related consume : public business fund, operation fund related event facilities, participation fee, and ticket fee, selling income of gift related events, food, information service, rental service, insurance service, income of transport and lodging. 3. The effect of sports industry development : sports products, the advance of technological industry, facilities, information technique. 4. The effect of employment promotion : promotion for short period, social resource for a long term effect with accumulation of brain and management know-how. The way for advance to maximize the economic effect of sports events are as follows; 1. Correspondence for periodic request. 2. participants of sports events should prepare proper event facilities. 3. Correspondence for the movement from urban-centered sports events to local events. 4. A pattern of event which have from of enterprise that a enterprise will use the sports events as means of advertisement. Sports events should present the innovation vision for new-life to get original meaning and function.

      • SCOPUSKCI등재

        스테로이드 여드름과 여드름양 발진에서 Malassezia (Pityrosporum) 효모균의 출현 빈도

        이수근,김재홍,양홍윤,김윤석,유희준,손숙자 대한의진균학회 1998 대한의진균학회지 Vol.3 No.1

        Background: Steroid acne is a folliculitis that can result from a systemic or topical administration of steroid and has been described as showing similar clinical pictures to Malassezia folliculitis, but there have been few reports about the incidence of Malassezia in steroid acne and other acneiform eruptions. Objective: Our purpose was to describe the incidences of Malassezia in acneiform eruptions and to discuss about the relationship between clinical steroid acne and Malassezia folliculitis. Methods: The history, clinical features, direct microscopy, histopathological analysis, and therapeutic results of 125 cases with steroid acne or other acneiform eruptions were described and compared. Results: Over 80% of patients with acneiform eruption receiving systemic steroid revealed significant numbers of Malassezia in the lesional follicle. Conclusion: Steroid acne and other acniform eruptions showing discrete follicular papules and/or pustules localized to the upper trunk or acneiform facial skin lesions associated with multiple acneiform lesions on the body in the summer period should be suspected as Malassezia folliculitis. [Kor J Med Mycol 3(1): 24∼32]

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