일부 산업장 근로자들의 직업성 피부질환 및 천식의 유병조사

윤지석,이영수,조영채,이동배 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

For the analysis of prevalence of occupational skin diseases and asthma in industrial workers, we studied the 1,274 workers who were engaged in manufacturing workers(direct exposured group to harzardous materials) and clerical workers (indirect exposured group to harzardous materials). The results were as follows: 1. The prevalence rate of occupational skin diseases and asthma in manufacturing workers(36.4%) was significantly higher than that in clerical workers(25.2%) (p<0.005). 2. The prevalence rates of skin diseases(p<0.005) and asthma(p<0.05) in male manufacturing workers were significantly higher than those in clerical workers, and the prevalence rate of asthma(p<0.005) in female manufacturing workers was significantly higher than that in clerical workers. 3. Of asthma in twenties(p<0.005), of skin diseases(p<0.005) and asthma(p<0.05) in thirties, the prevalance rate of manufaturing workers were higher than thoses of clerical workers, however no diffrence was in forties. 4. Of skin diseases(p<0.005) and asthma(p<0.05) in metal plating, of asthma(p<0.005) in cotton spinning, the prevalence rate of manufacturing workers were significantly higher than those of clerical workers. 5. The prevalence rate of skin diseases and asthma in dustness part were significantly higher than those of non-dustness part and poor ventilation part also were significantly higher than good ventilation part (p<0.005). 6. Frequency of involved skin sites, in descending order, were hand(32.1%), leg(24.3%), trunk(20.4%), face(12.1%) and arm(11.1%).

신손상 환자의 치료에 따른 임상적 고찰

윤종선,소영석,안병수,노준,박도영 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

장루 보유자의 생활 만족도 조사

서현석,이석환,고영관,오수명,윤충,주흥재,이기형 대한대장항문학회 1998 Annals of Coloproctolgy Vol.14 No.3

인벌류우트 기어 호빙 과정에 대한 해석

최석문,이상조,윤영식 연세대학교 산업기술연구소 1991 논문집 Vol.23 No.2

The cutting amount of each tooth in gear hobbing has much influence on the vibration of the hob axis and the wear of tool. In this study, with the simulation of gear hobbing mechanism, cutting parameters such as cutting thickness, cutting are and area moment were calculated. The cutting torque was also obtained by the experiments. The cutting amount of each tooth in the hob can be compared quantitatively by the simulation on the calculated cutting zone, cutting thickness and cutting are. And the cutting torque obtained by the experiments has the same tendency with the area moment calculated by the simulations. The results of this study can be applied to the research on the tool wear, the hob having modified tooth profile and the variation of cutting torque.

PECVD에 의해 제조된 Sb-doped SnO₂박막의 광학적성질

김근수,윤석영,김광호 부산대학교 생산기술연구소 2000 生産技術硏究所論文集 Vol.58 No.-

플라즈마를 이용한 화학증착법 (PECVD)으로 Corning glass 1737 기판에 Sb-doped SnO2 박막을 증착하였다. 플라즈마 화학증착시 반응변수에 따른 박막의 결정상, 표면형상 및 광투과도를 XRD, SEM, AFM 과 그리고 UV-VIS-NIR Spectrophotometer를 이용하여 분석하였다. Thermal CVD에 비해 PECVD법은 박막의 증착속도를 향상시켰고, 박막의 표면형상을 보다 균일하게 하였다. 반응온도 450℃, 유입가스비 R=1.12, RF power 30W에서 결정성과 광투과도가 비교적 뛰어난 Sb-doped tin oxide films을 얻을 수 있었다. Sb-doped tin oxide films were deposited on Coming glass 1737 substrate by plasma enhanced chemical vapor deposition (PECVD) technique. The films deposited at different reaction parameters were investigated by using XRD, SEM, AFM, and UV-VIS-NIR Spectrophotometer. Compared to thermal CVD,PECVD effectively enhanced the deposition rate and smoothed the surface of tin oxide films. Sb-doped tin oxide films which have a relatively good crystallinity and photo-transmission were obtained at deposition temperature 450℃, input gas ratio R=1.12, and RF power 30W.

우유와 두유를 혼합한 이유보충음료의 개발

손경희,윤선,이민준,김순영,김용태,장동훈,강석필 연세대학교 생활과학연구소 2001 生活科學論集 Vol.10 No.1

The purpose of this study is to develop an infant supplement composed of cow and soy milk which has acceptable taste and digestability and meets nutritional needs of the infants. Even though soy milk is and excellent source of protein for infants who are allergic to dairy products, its protein quality is still lower than that of regular milk. Therefore in the present study the development of sow-soy milk infant formula was attempted. To make the formula equal amount of cow and soy milk were mixed and supplemented with vitamins and minerals to meet the nutritional standards of breast milk, CODEX and recommended dietary allowances for Korean infants. In animal experimental study, the weight gain rate of weaning rats was highest in the order of 100% milk, cow-soy milk, control, soy milk, commercial soy infant milk group. Feed efficiency ratio(FER) were not significantly different among control, 100% milk and cow-soy milk groups. However, commercialized soy infant milk group showed significantly lower FER than other groups. When the cow-soy milk formula was fed to infant in the age of 5 month to 25 months, it did not show any unsatisfactory results in acceptability and bowel movements of the subjects. Since the cow-soy milk formula has not only all the nutrients for the physical growth of infants but also contains valuable physiological functional ingredients, it is expected to be a good choice of supplements for infants.

자궁내 발육지연이 있는 출생체중 2,500 g 이상인 환아의 주산기 예후에 관한 연구

송태복,조명숙,하진아,윤대석,김철홍,김윤하,최영륜 全南大醫大 2004 전남의대학술지 Vol.40 No.1

비혈연간 동종골수이식에 의해 치료된 중증 재생불량성빈혈 1예

김현중,이홍기,이방훈,이창근,이종태,정현식,김원석,윤성수,강원기,박근칠,김대식,고영혜,박찬형 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1

비혈연간 동종골수이식은 혈연간 동종골수이식이 불가능한 환자에서 기존의 면역역제요법으로 효과가 없었던 경우나 재발한 경우에 적응증이 될수 있다. 이식 거부와 이식편대숙주병의 발생이 골수 이식의 성공률을 감소시키므로, 보다 강력한 conditioning regimen의 사용과 T cell이 제거된 골수를 사용하는 것이 필요하다. 기존의 high dose corticosteroid나 cyclosporine에 대하여 불응성인 이식편대숙주병의 치료를 위해서 ATG와 Mycophenolate mofetil (Cellcept®) 의 사용이나 Tacrolimus, Methotrexate와 같은 다른 면역억제제치료를 고려해 볼 수 있다. It is known that allogenic bone marrow transplantation is the most effective treatment for aplastic anemia. However, this treatment is only applicable to a minority of patients because the proportion of patients who have HLA-matched siblings about 25% to 30% of all the aplastic anemia patients. In the case of the absence of HLA-matched donor, unrelated allogenic bone marrow transplantation is considered. However, (because of severe acute and chronic GVHD and graft failure) the success rate of this approach is only 20~30%. Recently, it was reported that increased immunosuppressive condition combined with T cell depletion of the marrow graft would result in greater success. There was no case of successfully treated aplastic anemia patient by unrelated allogenic bone marrow transplantation in Korea. Here, we report a case of severe aplastic anemia successfully treated with unrelated allogenic bone marrow transplantation.

마이크로파에 의한 생분해성 β-TCP/PLGA 복합체의 제조시 β-TCP 첨가량에 따른 영향

진형호,민상호,박홍채,윤석영,Jin, Hyeong-Ho,Min, Sang-Ho,Park, Hong-Chae,Yoon, Seog-Young 한국재료학회 2006 한국재료학회지 Vol.16 No.1

Biodegradable $\beta$-tricalcium phosphate ( $\beta$-TCP)/poly(lactide-co-glycolide) (PLGA) composites were synthesized by in-situ polymerization with microwave energy. The influence of the $\beta$-TCP content in $\beta$-TCP/PLGA composites on the molecular weight, crystallinity, microstructure and mechanical properties was investigated. As the molecular weight of composites decreased, the $\beta$-TCP content increased up to 10 wt.%, while the excess addition of the $\beta$-TCP content above 10 wt.% the molecular weight increased with increasing of the $\beta$-TCP content. This behavior would be due to the superheating effect or nonthermal effect induced by microwave energy. It was found that the bending strength and Young's modulus of the $\beta$-TCP/PLGA composites was proportional to the molecular weight of PLGA. The bending strength of the $\beta$-TCP/PLGA composites ranged from 18 to 38 MPa, while Young's modulus was in the range from 2 to 6 GPa.

The behavior of collagen-like molecules in response to different temperature setting methods in steered molecular dynamic simulation

Young-June Yoon(윤영준),Kang-Hee Cho(조강희),Seog-Young Han(한석영) 한국정보전자통신기술학회 2020 한국정보전자통신기술학회논문지 Vol.13 No.5

타입 1 콜라겐 단백질은 인체 내에서 가장 많이 존재하는 단백질이다. 이 단백질은 점탄성 거동을 보이며 이는 힘줄에서도 찾아볼 수 있다. 분자동역학 시뮬레이션 방법에는 rescaling 방법과 reassignment 방법으로 온도를 조절할 수 있다. rescaling 방법은 온도를 주어진 온도로 책정하는 방법이고, reassignment 방법은 원하는 온도로 맥스웰 분포를 이용하여서 온도를 책정하는 방법이다. 우리는 reassignment 방법에서 콜라겐 단백질의 거동이 시간에 따라서 변화하는 현상을 찾아내었다. 반면에 rescaling 방법에서는 시간에 무관하게 거동하였다. 콜라겐에 다른 속도로 인장을 가하였을 경우, 예를 들어 0.5, 1, 2, 5 Å/ps의 속도로 40 Å까지 힘을 가했을 경우, rescaling 방법에서는 속도에 따른 변화가 거의 없었던 반면, reassignment 방법의 경우 대략 80nm, 100nm, 130nm, 180nm까지 인장이 되었음을 보여준다. 이 현상에 대한 물리학적 의미를 명확하게 규명하지는 못하였지만, 단백질에 관한 시뮬레이션을 실행하는데 있어서 주의를 기울여 수행하여야 한다는 점에서 이 논문의 가치가 있다고 생각한다. Collagen type I is the most abundant protein in the human body. It shows viscoelastic behavior, which is what confers tendons with their viscoelastic properties. There are two different temperature setting methods in molecular dynamics simulations, namely rescaling and reassignment. The rescaling method maintains the temperature by scaling the given temperature, while the reassignment method sets the temperature according to a Maxwell distribution at the target temperature. We observed time-dependent behavior when the reassignment method was applied in tensile simulation, but not when the rescaling method was applied. Time-dependent behavior was observed only when the reassignment method was applied or when one side of the collagen molecule was stretched to a greater extent than the other side. As result, the collagen is elongated to 80nm, 100nm, 130nm, and 180nm, respectively, when the collagen is pulled by different velocities, 0.5, 1, 2, and 5 Å/ps, up to 40 Å. The results do not provide a detailed physical explanation, but the phenomena illustrated in this result are important for caution when further simulations are performed.