국방 기사 자동 분석 시스템 구축 방안 연구

김현중,김우주 한국군사과학기술학회 2018 한국군사과학기술학회지 Vol.21 No.1

Since media articles, which have a great influence on public opinion, are transmitted to the public through various media, it is very difficult to analyze them manually. There are many discussions on methods that can collect, process, and analyze documents in the academia, but this is mostly done in the areas related to politics and stocks, and national-defense articles are poorly researched. In this study, we will explain how to build an automatic analysis system of national defense articles that can collect information on defense articles automatically, and can process information quickly by using topic modeling with LDA, emotional analysis, and extraction-based text summarization.

인증 정보 관리를 위한 기술 동향과 AIM 프레임워크 연구 및 설계

김현중,차병래,반성범 한국디지털정책학회 2016 디지털융복합연구 Vol.14 No.7

다층모형과 공간 클러스터 기법을 활용한 농업 주산지의 집적지 변화 분석

김현중,이성우 한국지역학회 2013 지역연구 Vol.29 No.4

The present study aims to investigate the degree of regional specialization of vegetables and locate the clusters of their main production areas. We adopt a multi-level model to analyze the level of specialization along with the application of Local Moran's I to identify the spatial shifts of vegetables clusters in the major agricultural producing areas. All the data used in the study is derived from a single source; Census of Agriculture, Forestry and Fisheries, a national agricultural census in Korea released every five years. Analyses are conducted based on all of the local autonomous units (Si, Gun and Gu) in Korea, and the time scope of the analysis is limited to the years from 1995 to 2010. According to the results, Sinan, Jindo, Haenam, Seoguipo and Namjeju are the cluster of major producing areas of both open field vegetables and greenhouse vegetables. However, the clusters of major producing areas have been frequently changed. The present study showed the limitations in policies that have been enforced to reinforce the clusters of specialized crops and to improve the balance of supply and demand of vegetable crops. 본 연구의 목적은 미시자료를 활용하여 지역별 채소의 특화수준을 분석하고, 주산지의 집적지를 식별하는 한편, 그 변화 양상을 살펴보는 데에 있다. 농산업의 특화수준은 다층모형을, 그리고 주산지의 직접지 식별에는 공간 클러스터 기법의 하나인 Local Moran’s I를 각각 활용하였다. 분석에 활용된 자료는 5년 단위로 제공되는 농립어업총조사이며, 전국의 시군구를 대상으로 1995년부터 2010년까지 분석하였다. 분석결과, 노지채소와 시설채소에서 신안군, 진도군, 해남군, 서귀포시와 남제주군이 모든 분석년도에서 채소 주산지의 집적지로 나타났다. 그러나 전반적으로 볼 때, 노지채소와 시설채소 주산지의 집적지는 잦은 변화를 겪어 온 것으로 드러났다. 이러한 분석결과는 주산지 거점지역의 경쟁력 강화를 통한 채소의 수급균형을 제고하고 경영성과를 높이는데 일정 부분 한계가 있었음을 확인시켜 준 것이라 할 수 있다.

지자체의 농업통계정보 이용 실태와 체계화 사례

김현중,임준혁,김나리,김상태 한국농촌경제연구원 2020 한국농촌경제연구원 기본연구보고서 Vol.- No.-

토양에서 분리한 국내 미기록종 Pseudomonas 속 6종의 생화학적 특성과 계통 분류

김현중,정유정,김해영,허문석,Kim, Hyun-Joong,Jung, You-Jung,Kim, Hae-Yeong,Hur, Moonsuk 한국미생물학회 2019 미생물학회지 Vol.55 No.1

생명공학산업의 주요한 자원인 미생물의 가치는 날로 증대하고 있으며, 이로 인해 생물자원을 확보하기 위한 국가간의 경쟁은 심화되고 있다. 이에 다양한 환경에서 미생물자원을 발굴하고 특성을 확인하는 것은 미래의 잠재적 생물자원을 확보하는데 큰 의미가 있다. 본 연구에서는 Pseudomonas속에 속하는 6종의 미생물들을 일반 토양에서 분리하여 분자계통학적 분석을 통해 국내 미기록종임을 확인하였다. 본 연구로 확보된 미생물들은 자생 생물자원의 다양성을 늘리고, 산업계에 생물자원의 선택의 폭을 늘리는데 도움이 될 것으로 기대된다. In 2017, as a study to discover indigenous prokaryotic species in Korea, a total of 6 bacterial strains assigned to the genus Pseudomonas were isolated from soil. From the high 16S rRNA gene sequence similarity (${\geq}99.5%$) and phylogenetic analysis with closely related species, the isolated strains were identified as independent Pseudomonas species which were unrecorded in Korea. The six Pseudomonas species were Pseudomonas mandelii, P. canadensis, P. thivervalensis, P. jessenii, P. lurida, and P. brenneri. Gram reaction, culture conditions, colony and cell morphology, basic physiological and biochemical characteristics are described in the species description section.

새로운 임산버섯 " 잣버섯과 뽕나무버섯 " 의 톱밥재배

김현중,고민규 ( Hyun Joong Kim,Min Kyoo Ko ) 한국균학회 1995 버섯재배 기술개발 특별강연회 Vol.- No.-

Value of image subtraction for the identification of hepatocellular carcinoma capsule on gadoxetic acid-enhanced MR images

김현중,안지현,문진실,차승환 대한영상의학회 2018 대한영상의학회지 Vol.79 No.6

Purpose To evaluate value of image subtraction for identifying hepatocellular carcinoma (HCC) capsule on gadoxetic acid-enhanced MR images. Materials and Methods This study involved 108 patients at risk of HCC preoperatively examined using gadoxetic acid-enhanced MRI with hepatic resection between May 2015 and February 2017. We evaluated qualities of subtraction images and presence of capsular appearance on portal venous or transitional phases conventional and subtraction images. We assessed effect of capsular appearance on subtraction images on HCC. Results After excluding 1 patient who had treated by transarterial chemoembolization prior to surgery and 33 patients with unsatisfactory subtraction image qualities, 82 focal hepatic lesions (73 HCC, 5 non-HCC malignancies, and 4 benign) from 74 patients were analyzed. Regarding detection of capsules, sensitivity, accuracy, and area under the receiver operating characteristic curve (AUC) on subtraction images were significantly higher than those on conventional images (95.4%, 89.0%, and 0.80, respectively; P<0.001), though specificities were same (64.7%). For diagnosis of HCC, sensitivity, accuracy, and AUC on subtraction images were significantly higher than on conventional images (82.2%, 79.3%, and 0.69, respectively; P=0.011), though specificities were identical (55.6%). Conclusion Portal venous or transitional phase gadoxetic acid-enhanced MRI subtraction images could improve detection of HCC capsule.

Panax ginseng as an adjuvant treatment for Alzheimer’s disease

김현중,Seok-Won Jung,김석영,조익현,Hyoung Chun KIM,Hyewhon Rhim,김만호,나승열 고려인삼학회 2018 Journal of Ginseng Research Vol.42 No.4

Longevity in medicine can be defined as a long life without mental or physical deficits. This can be prevented by Alzheimer’s disease (AD). Current conventional AD treatments only alleviate the symptoms without reversing AD progression. Recent studies demonstrated that Panax ginseng extract improves AD symptoms in patients with AD, and the two main components of ginseng might contribute to AD amelioration. Ginsenosides show various AD-related neuroprotective effects. Gintonin is a newly identified ginseng constituent that contains lysophosphatidic acids and attenuates AD-related brain neuropathies. Ginsenosides decrease amyloid b-protein (Ab) formation by inhibiting b- and g-secretase activity or by activating the nonamyloidogenic pathway, inhibit acetylcholinesterase activity and Abinduced neurotoxicity, and decrease Ab-induced production of reactive oxygen species and neuroinflammatory reactions. Oral administration of ginsenosides increases the expression levels of enzymes involved in acetylcholine synthesis in the brain and alleviates Ab-induced cholinergic deficits in AD models. Similarly, gintonin inhibits Ab-induced neurotoxicity and activates the nonamyloidogenic pathway to reduce Ab formation and to increase acetylcholine and choline acetyltransferase expression in the brain through lysophosphatidic acid receptors. Oral administration of gintonin attenuates brain amyloid plaque deposits, boosting hippocampal cholinergic systems and neurogenesis, thereby ameliorating learning and memory impairments. It also improves cognitive functions in patients with AD. Ginsenosides and gintonin attenuate AD-related neuropathology through multiple routes. This review focuses research demonstrating that ginseng constituents could be a candidate as an adjuvant for AD treatment. However, clinical investigations including efficacy and tolerability analyses may be necessary for the clinical acceptance of ginseng components in combination with conventional AD drugs.

Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease

김현중,장신이,박중일,변종회,김동익,도영수,김종묵,김선영,김병문,김원배,김덕경 생화학분자생물학회 2004 Experimental and molecular medicine Vol.36 No.4

This phase 1 clinical trial tested the safety of intramuscular gene transfer by using naked plasmid DNA encoding the gene for VEGF, and analyzed the potential therapeutic benefits in patients with severe peripheral arterial disease (PAD). This study was an open-labeled, doseescalating, single-center trial on nine male patients with severe debilitating PAD who had not responded to conventional therapy. Seven had Buerger's disease and two had arteriosclerosis obliterans. Plasm id DNA (pCK) containing human VEGF165 was given by eight intramuscular injections in and around the area in need of new blood vessels. The study evaluated three escalating total doses (2, 4, and 8 mg of pCKVEGF165), with half of each total dose given four weeks apart. The follow-up duration was nine months. The gene injections were well tolerated without significant side effects or laboratory abnormalities related to gene transfer. Three patients showed transient edema in their extremities. Ischemic pain of the affected limb was relieved or improved markedly in six of seven patients. Ischemic ulcers healed or improved in four of six patients. The mean ankle-brachial index (ABI) improved significantly. Six of nine patients showed an increase in collateral vessels around the injection sites demonstrated by digital subtraction angiography. However, there was no relationship between the degree of ABI improvement and the dose given. Mean plasma levels of VEGF d id not increase significantly. In conclusion, intramuscular in jections of pCKVEGF165 can be performed safely to induce therapeutic angiogenesis in patients with severe PAD.

WCDMA용 67-dB DR, 1.2-V, $0.18-{\mu}m$ 시그마-델타 모듈레이터 설계

김현중,유창식,Kim, Hyun-Jong,Yoo, Chang-Sik 대한전자공학회 2007 電子工學會論文誌-SD (Semiconductor and devices) Vol.44 No.6

[ $0.18-{\mu}m$ ] CMOS 공정에서 1.2-V 2차 Full-Feedforward 구조의 ${\Sigma}{\Delta}$ 모듈레이터를 설계하였다. Full-Feedforward 구조는 Op-Amp의 성능 요구치를 크게 경감시키기 때문에 저전압 저전력 ${\Sigma}{\Delta}$ 모듈레이터를 만들기에 적합한 구조로 세계적으로 많이 채택되고 있는 추세이다. 그리고, Top-Down 설계 기법을 적용하여 ${\Sigma}{\Delta}$ 모듈레이터를 설계하였는데, 이를 위하여 Op-Amp의 유한한 DC-Gain과 Bandwidth 등 여러 가지 비이상적 효과들을 모델링하여 전달함수를 유도하였다. [ $0.18-{\mu}m$ ] CMOS 1.2-V 2nd-order ${\Sigma}{\Delta}$ modulator with full-feedforward topology is designed. Using full-feedforward topology makes op-amp performance requirements much less stringent, therefore it has been adopted as a good candidate for low-voltage low-power applications throughout the world. Also, ${\Sigma}{\Delta}$ modulator is designed with top-down design approach, therefore various nonideal effects of op-amp are modeled in this paper.