종설(綜說) : 한의학 학술지에 발표된 탈모에 관한 연구현황 분석

김광중 ( Kwang Joong Kim ),백승엽 ( Seung Yeob Baek ),임채광 ( Chae Kwang Im ) 대구한의대학교 제한동의학술원 2012 東西醫學 Vol.37 No.4

We performed a systemic analysis of the research situations on hair and alopecia published in the journal of oriental medicine to understand the search trend in the area of hair and alopecia, prepare the basis for the interests and basis on hair and alopecia in the oriental medicine area and above that, to support for the applications in the clinics through this and came to the following conclusions. 1. There are total 95 publications in the domestic journals of oriental medicine area from 1986 to 2011. 2. Total 95 articles were published in 23 journals. “Dong-eui journal of physiology and pathology” had the largest number of articles which was 22(23%) followed by “Oriental journal of ophthalmology, otolaryngology, and dermatology” of 19(20%). 3. The authors who published the largest number of articles as the first author were “Cheon-jong Kim”, “Hyeon-taek Shin”, and “Tae-hu Lee” who published 3 each, and the correspondent author who published the largest number of articles was “Chang-hyeon Lee” who published 8 articles. 4. For the contents and methodologies of the study, there were 16 literature reviews, 36 clinical trials, and 43 animal and other experimental studies and 3 literature reviews were published in 2002, 6 animal and other experimental studies were published in 2006, and 6 clinical trials were published in 2004, 2006, 2009, and 2010 each the most. Based on this study, we hope not only scientific treatises but also these for the oriental medicines and alopecia study related to the oriental medicines to be continued.

경락(經絡)과 정신양생(精神養生)의 관계 설정(設定)에 대(對)한 고찰(考察)

백진웅,김광호,Baek Jin-Woong,Kim Kwang-Ho 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.2

It is thought that Kim Hong-kyeong followed the existing theory of Meridian(經絡) and supplemented his unique perspectives in interpreting it. And he tried to relate Meridian with hygiene of mind. I took up with the research on the assumption that the review of Kim's method can present new perspectives to the study of relationship between Meridian and hygiene of mind. The results of my study are as follows: 1. Kim followed common theory of Meridian and then added his unique perspectives to it. His method of interpretation has one characteristic. By introducing Idealism(唯心論), he understood 'Meridian' as the path of the mind and the emotion. Especially I think his hypothesis that acupuncture can be widely used in mental diseases as well as body related diseases and its applications to treatment are very valuable. 2. Meridian and hygiene of mind are close together. I think Kim's unique trial is something new in studying relationship between Meridian and hygiene of mind but requires more research on it.

흉부외상 없이 발생한 흉부대동맥 절단증의 조기 진단 : 2례 보고 Two Cases Report

한승백,전영진,백광제,김준식,김정택,김광호,선경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Aortic transection or interruption is a rare condition which developed after an acute deceleration injury. Its occurrence depends on the location and direction of the force applied and is usually from motor vehicle accident or falling down. The exact incidence of aortic transection in trauma is not known but, when develops, only about 10-15% of the victims can survive and be transported to the hospital. Even in the survivors, majority of them will be fatal within a few days if a prompt diagnosis and surgical treatments are not made. Aggressive diagnostic work-up is recommended for the patients with high suspicious index, which would salvage the victims with this fatal condition. We report the experience of two cases of aortic transection or interruption following motor vehicle accidents.

성인성 호흡부전증(ARDS)의 호흡역학 개선을 위한 실험연구

백광제,김준식 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

The acute respiratory distress syndrome (ARDS) is a disorder of diffuse lung injury secondary to a wide variety of clinical insults including sepsis. It is manifested by impaired oxygenation, pulmonary edema, decreased static and dynamic compliance of lung, and increased airway resistance. Reduced lung compliance together with increased airway resistance is a hallmark of the syndrome and has generally been considered as the primary abnormality of lung mechanics. The study was designed to reproduce an ARDS condition in an animal model with acute lung injury and to determine whether these changes are reversed by inhalation of aerosolized bronchodilator such as salbutamol or nicorandil. Six adult mongrel dogs were exposed to intravenous oleic acid (0.08 ml/kg) mixed into a same amount of pure enthanol. We defined a condition of PaO2 less than 60 mmHg in FiO2 0.6 as an acute diffuse lung injury. Lung mechanics were deteriorated after oleic acid injection, from 27.33±2.73 to 17.50±7.47 cmH2O/1/sec in compliance and from 14.55±4.46 to 26.33±6.02 ml/cmH2O in airway resistance. Salbutamol or Nicorandil inhalation significantly improved lung compliance to 30.67±11.30 or 36.33±9.00 cmH2O/1/sec and airway resistance to 16.77±7.47 or 19.55±5.45 ml/cmH2O. From above data, we carefully concluded that compromized lung mechanics in adult respiratory distress syndrome could be effectively managed by inhalation of aerolized bronchodilator.

농산 폐기물인 Allium속 뿌리를 이용한 Ni와 Pb 이온 제거

김성조,백승화,김운성,문광현 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.6

농산물의 갈무리시 발생되는 건조한 마늘, 쪽파 및 대파 뿌리 분말을 흡착제로 이용하여 수용액 중 이온 상태로 존재하는 Ni과 Pb의 흡착력을 시료의 입자별, 중금속의 농도별, 용액의 온도별, pH별로 분석하였다. 중금속 이온들은 흡착제의 입자크기가 작을수록 흡착률이 높았고, 그중 마늘뿌리가 Pb에 대해 높은 흡착력을 나타냈다. 수용액중 중금속 농도가 높을수록 중금속들이 흡착되는 양이 증가하였고, 흡착률은 흡착제와 중금속의 종류에 따라 차이가 있었다. 온도의 증가는 쪽파와 대파에서 Ni과 Pb가 감소되었다. 알칼리 조건에서 비교적 흡착이 잘 되는 중금속은 Ni이며, 중성과 산성조건에서는 Pb의 흡착량이 높았다. A batch experiment was conducted to evaluate the removal capacity of welsh onion(Allium fistulosum L.), shallot(Allium ascalonicum L.), garlic(Allium sativum L.) roots as an adsorbent for Ni and Pb in aqueous solution. One gram of the dried Allium root powder was reacted in 100ml of solution containing 10㎎ of each heavy metal and effects of metal concentration, pH, temperature, and size of adsorbent on the removal efficiency were evaluated. The results were as follows : The amount of adsorption of heavy metal ions were higher with the smaller particles size of adsorbent. Garlic root was high adsorption capacity of Pb, especially. The higher concentration of heavy metal solution was, the more amount of adsorption of heavy metals was. The adsorption ratio was differed from a kind of heavy metal. As the temperature increased, the amount of adsorption of Ni and Pb by shallot and welsh onion were decreased. The amount of adsorption of Ni was high under alkali conditions but the amount of adsorption of Pb was high under neutral and acidity condition.

퍼지 이론을 이용한 영상 이진화에 관한 연구

김광백 신라대학교 자연과학연구소 2003 自然科學論文集 Vol.12 No.-

The image binarization is applied frequently as the one part of the preprocessing phase for a variety of image processing techniques such as character recognition and image analysis, etc. The setting of the threshold value influences the performance of the binarization algorithms, and most of the previous binarization algorithms analyze the intensity distribution of the original images by using the histogram and determine the threshold value using the mean value of intensity or the intensity value corresponding to the valley of the histogram. The previous algorithms could not get the proper threshold value in the case that doesn't show the bimodal characteristic in the intensity histogram or for the case that tries to separate the feature area from the original image. In this paper, I proposed a method that establish dynamically threshold using triangle type membership function about images. The proposed fuzzy binarization method establishes smallest brightness value and maximum brightness value using the control rate of brightness calculating the darkest pixel value and distance of lightest pixel price via average brightness value and applies in membership function of triangle. Through the membership is applied a -cut rule about membership function, the image is binarized. The experiment for the performance evaluation of the proposed binarization algorithm showed that the proposed algorithm generates the more effective threshold value than the previous algorithms.

허혈 조건부여가 심근기능의 회복에 미치는 영향 : 적출 심장모델을 이용한 실험연구 Isolated heart experimental study

백광제,김준식,한승백,전영진,이인성 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: Brief episode of coronary artery occlusion(i.e.,ischemic preconditioning) makes the heart more resistant to injury from a subsequent ischemic insult. Although a great deal of effort has been made in studying ischemic preconditioning, the underlying mechanism of ischemic preconditioning and its effect on hypothermic insult has not been elucidated. This study was performed to see whether ischemic preconditioning protects against the depression of cardiac contractility induced by hypothermic cardioplegic arrest/reperfusion. And recently, adenosine was known to have some correlation with the mechanism of preconditioning. If so, does this effect remain after the blockade of adenosine receptor by 8-phenyl theophyline? Method: Twenty-four Sprague-Dawley rat weighed 250-350g were used and divided into three groups. Rat hearts were removed rapidly, and each isolated heart paced with a rate of 180/min was perfused by modified Krebs-Hensleit buffer(KHB) solution on a Langendorff apparatus for an hour. After obtaining baseline data including left ventricular pressure(LVP), dp/dt, and coronary flow, cardiac arrest was induced by perfusion of 0℃ crystalloid cardioplegic(St Thomas) solution. After that, all hearts were stored in the same St Thomas solution at same temperature for 2 hours. In group Ⅰ(control group), the heart was reperfused by KHB solution. In group Ⅱ(preconditioning group), the heart was subjected to two 2-minute episode of global ischemia followed by 5 minute reperfusion with KHB solution(preconditioning) before cardiac arrest. In group Ⅲ(phenyl theophylline group), the heart was subjected to preconditioning procedure and 8-phenyl theophylline at 10μM in concentration was added to KHB solution at time of reperfusion. Observing parameter was obtained in each group at 10, 20, 40 and 60 minutes after starting reperfusion and compared statistically by use of one way ANOVA test(STASTICA, release 4.5). p-value less than 0.05 was considered significant. Results: Although depressed LVP, dp/dt, and coronary flow were seen in all groups during the reperfusion period, the preconditioned group showed more effective recovery of LVP than that of the control group, especially at 10, 20 and 40 minutes(p<.05). We failed to demonstrate the difference between the phenyl theophylline group and the control group(p=NS). Conclusion: These results suggest that ischemic preconditioning has protective effect on recovery state of hypothemic cardioplegic arrest/reperfusion. Its protective effect was limited during early reperfusion stage and was blocked by adenosine blocker.

晉州 附近 新洞層群(下部 白堊系)에서 産出되는 化石 Stromatolite의 生堆積 構造 및 古環境

金榮汶,白光錫,徐承祚 晋州敎育大學校 科學敎育硏究所 1998 科學敎育硏究 Vol.24 No.-

For the purpose of clarifying the organosedimentary structure and paleoenvironment of stromatolites from the southem part of the Kyongsang Basin, the study was carried out both through the field works and chemical analysis of samples. Obtained data were compared with the repotred ones from areas in North Kyongsang Province, additionally. Through this study, the paleaoenvironments of these areas were summarized as follows: 1. Laminations of stromatolite are consist of algal-rich and sediment-rich laminae altemately. The content of calcite, main component of stromatolite, has less Magnesium value. Thus, it seems to have formed under the fresh water environment. 2. The almost of the stromatolites have very irregular shapes which has been caused by disturbed and divided algae from microbial activities. Therefore, it can be inferred that the lake was calm. 3. It seems to have been shallow lacustrine environment and intermittent dry season.

개선된 퍼지 단층 퍼셉트론

김영주,김광백 新羅大學校 2003 論文集 Vol.52 No.-

The traditional SLP(Single Layer Perceptron) can apply to only the classification of inputs into output patterns being linearly separable, and can't solve the nonlinear problems such as Exclusive-OR, etc. The Fuzzy SLP applied the fuzzy membership functions into the SLP to solve the nonlinear problems by using the perceptron with single layer structure. The Fuzzy SLP shows, however, the remarkable defects being the oscillation of the decision-boundary lines and the decline of the potentiality of convergence. This paper proposed the "Enhanced Fuzzy SLP" algorithm which introduced the term of bias into the Fuzzy SLP to avoid the oscillation of the decision-boundary lines, improving the potentiality of convergence, and applied the concepts of dynamic learning rate and momentum to reduce the required time for learning. This paper, for performance evaluation, performed the benchmark test of the proposed algorithm and the Fuzzy SLP on two problems, the Exclusive-OR problem and the classification of numeric patterns. Being Compared on the metrics of the number of epoch and the potentiality of convergence, the proposed algorithm showed the reduction of the learning time and the improvement of the potentiality of convergence.

레진 계열 근관봉함재 Adseal의 세포독성에 관한 연구

김희정,백승호,이우철,박한수,배광식 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.6

The properties of ideal root canal sealers include the ability of sealing the total root canal system and no toxic effects to periradicular tissues. Cytotoxicity test using cell culture is a common screening method for evaluation of the biocompatibility of root canal sealers. The purpose of this study was to investigate the cytotoxic effect of newly developed resin-based sealer (Adseal 1, 2, and 3) comparing with those commercial resin-based sealers (AH26 and AH Plus), ZOE-based sealers (Tubliseal EWT, Pulp Canal Sealer EWT) and calcium hydroxide based sealer (Sealapex). An indirect contact test of cytotoxicity by agar diffusion was performed according to the international standard ISO 10993-5. L929 fibroblast cells were incubated at 37℃ in humidified 5% CO₂-containing air atmosphere. The freshly mixed test materials were inserted into glass rings of internal diameter 5 ㎜ and height 5 ㎜ placed on the agar. After the 24 hrs incubation period, the decolorization zones around the test materials were assessed using an inverted microscope with a calibrated screen. A Decolorization Index was determined for each specimen. Adseal 1, 2, and 3 did not exert any cytotoxic effects, whereas AH26, AH Plus, Tubliseal EWT, Pulp Canal Sealer EWT, and Sealapex produced mild cytotoxicity.