췌장염에 의한 가성낭종내에 생긴 가성동맥류 : 1례 보고

오연희,이채경,김승현,이성우,양창현,이정호,이영현 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

만성 췌장염의 합병증으로 생긴 가성동맥류는 드문질환으로, 반복적으로 다량의 출혈을 일으킬 수 있으며, 치료를 하지 않을 경우 사망율이 높기 때문에, 조기 진단과 치료가 필수적이다. 저자들은 38세 남자 환자에서 췌장염의 합병증으로 생긴 가성낭종내에서 발생한 가성동맥류 1예를 경험하였기에 보고하는 바이다. 가성 동맥류의 색혈류도플러상 낭종내에 양방향 흐름의 와류를 볼 수 있었다. Pancreatic Pseudoaneurysm within Pseudocyst from Pancreatitis: 1 Case Department of Diagnostic Radiology and Internal Medicine, College of Medicine,DongGuk University Yeon Hee OH M.D., Chae Kyeong Lee M.D., Seoung Hyeon Kim M.D., Sung Woo Lee M.D., Chang Heon Yang M.D., Jung Ho Lee M.D., Young Hyun Lee M.D. Pseudoaneurysm from pancreatitis is uncommon, but it can cause recurrent and massive hemorrhage. Because of high morbidity and mortality, early detection and treatment of the pseudoaneurysm is needed. We report a case of pseudoaneurysm within pseudocyst from pancreatitis. Color-flow Doppler sonography shows bidirectional flow and turbulent arterial flow, within anechoic mass.

발열을 동반한 호중구감소증에서 Cefepime 단독투여와 Ceftazidime 및 Tobramycin 병합투여의 효능비교

정현욱,채제욱,강미라,양정채,문치숙,기현균,장현하,오원섭,김기현,백경란,이남용,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 국내에서 발열을 동반한 호중구감소증이 있는 악성 종양환자에게 경험적 항생제로 베타락탐계 항생제와 아미노배당체의 병합요법의 사용이 일반적이다. Cefepime은 광범위 항균 작용을 가지고 있어, 그람 음성균 뿐만 아니라 그람 양성균에 대해서도 우수한 효과를 나타낸다. 재료 및 방법: 발열을 동반한 호중구감소증이 있는 악성 종양환자를 대상으로 무작위, 공개, 비교 연구를 시행하였다. 대상 환자를 무작위로 cefepime 단독요법군과 ceftazidime 및 tobramycin 병합요법군으로 나누어 투여하고 각각의 임상적 효능과 안전성을 비교하였다. 구강및 인후 점막염이 있는 환자에서 분리된 녹색 연쇄알 구균에 대한 항생제 내성 정도를 조사하였다. 결과 : 대상환자 89명 중 CA 투여군이 48예(53.9%), CT 투여군이 41예(46.1%)이었다. 발열의 유형별로 MDI는 18예(20.2%), CDI는 9예(10.1%), UF는 62예(69.7%)로 두 군 간에 차이가 없었다. CA 투여군과 CT 투여군의 임상적 호전률은 시험약 투여 후 2-4일째 각각 91.7%, 85.4% (P=0.31), 치료 종료 시 각각 91.7%, 100% (P=0.15)로 두 군간에 유의한 차이가 없었다. 치료 종료 시 CA 투여군과 CT 투여군의 세균학적 소실률은 모두 100%로 두 군간의 유의한 차이가 없었다(P=0.78). 점막염이 있는 환자로부터 녹색 연쇄알 구균이 분리된 경우는 25예(28.1%)이었으며, 분리된 녹색 연쇄알 구균은 penicillin, ceftriaxone, cefepime, vancomycin에 모두 감수성을 보였다. 약제 관련 이상 반응의 발생 빈도도 두 군간에 유의한 차이가 없었다. 결론 : 발열을 동반한 호중구감소증이 있는 악성 종양환자의 경험적 항생제로서 cefepime 단독요법은 ceftazidime 및 아미노배당체의 병합요법만큼 효과적이고 안전하였다. Background : Broad-spectrum antibiotic therapy has been recommended as an empirical regimen in cancer patients with febrile neutropenia. Cefepime is a fourth generation cephalosporin with good activity against both gram-positive cocci and gram-negative bacilli. Materials and Methods : To compare the efficacy and safety of cefepime alone with ceftazidime plus tobramycin as empirical regimen for adult cancer patients with febrile neutropenia, a randomized, open label, comparative trial was performed. If the patient showed clinical improvent 72 hours, antibiotic could be changed to oral ciprofloxacin. Clinical and microbiological responses were determined at 72 hours and at the end of therapy. To investigate the antimicrobial resistance of viridans streptococci, swab cultures were obtained from throat in all enrolled patients and antimicrobial susceptibility tests were performed by using microdilution method according to the NCCLS. Results : A total of 89 patients were enrolled. Forty-eight patients received cefepime alone (CA), and 41 patients received ceftazidime plus tobramycin (CT). Demographic and baseline clinical characteristics were similar in both groups (P>0.05). The initial clinical success rate at day 2-4 in group CA (91.7%) was similar with that in CT group (85.4%) (P=0.31). At the end of therapy, the final clinical success rate in CA group (91.7%) was similar to that in CT group (100%) (P=0.15). In 18 patients, with microbiologically defined infections, the eradication rate was 100% in both groups. Adverse events including liver dysfunction (21.3%) and renal dysfunction (2.2%), were similar in both groups (P=0.87). Viridans streptococci were isolated from the throat cultures in 25 cases, and all of these strains were susceptible to penicillin (MIC_(90) 0.12 ㎍/mL), cefepime (1 ㎍/mL), and vancomycin (0.12 ㎍/mL). Conclusion : Efficacy and safety of cefepime monotherapy was comparable to the combination of ceftazidime and tobramycin. It could be used as an alternative empirical regimen for treating cancer patients with febrile neutropenia.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

Phage 항원성에 미치는 trypsin의 영향

이현국,양남웅,서재홍 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

In order to investigate the effect of trypsin(TP) on the phage antigenicity, the Klebsiella phage-host cell system and sheep red blood cells were used, and the results were as follows. The neutralization velocity of Tp-treated phage(Tp phage) by anti-normal phage serum was faster than that of normal phage. And, the neutralization of normal phage by anti-Tp phage serum was remarkably worse than that of Tp phage. The normal phage - neutralizing activity of the anti-normal phage serum absorbed with Tp phage was very weak. However, the anti-Tp phage serum absorbed with normal phage still considerably neutralized the Tp phage. The cold phage hemagglutination(CPH) by normal and Tp phage was most favourable when the reactions are carried out with each phage-correspondig antiserum. The anti-normal phage serum absorbed with Tp phage and the anti-Tp phage serum absorbed with normal phage still formed, with each corresponding phage, the CPH. The neutralization of Tp phage, by anti-normal phage serum, Passed two times through host bacteria and that of Tp phage, by anti-Tp phage serum, Passed three times through host bacteria were similar to the neutralization of normal phage by each antiserum. If the Tp phage is passed two times or three times through host bacteria, the forming capability of CPH by each phage bacame similar, under the anti - normal and anti - Tp phage sera, to that of normal phage. The absorption of Tp phage to host bacteria was a little faster than that of normal phage. If the Tp tretment of phage is done for 48hours at 37℃, the surviving titer was reduced to around 40%.

電子文書交換 시스템의 利用效果 및 戰略經營 成果에 관한 文獻硏究

蔡明秀,李炫植 충남대학교 경상대학부설 경영경제연구소 1997 경영논집 Vol.13 No.1

電子文書交換(EDI) 시스템이 정보사회의 도래와 더불어 戰略經營의 핵심수단으로 등장함에 따라 우리나라에서도 EDI에 관한 學問的 관심이 최근에 고조되고 있다. 그럼에도 불구하고 EDI에 관한 國內의 先行硏究는 일천할 뿐더러 연구의 量과 質에 있어서도 매우 미미하다. 따라서 EDI가 기업의 戰略經營 成果에 구체적으로 어떤 影響을 미치고 있는가를 심층적으로 분석할 必要性이 크게 대두되고 있다. 이와 같은 硏究의 必要性에 따라 本考에서는 情報技術(IT)과 成果(performance) 分析에 관련된 최근의 선행연구를 綜合的·包括的으로 정리하였으며, 이들 선행연구들이 成果 分析에 사용한 구체적인 測定方法을 제시하고 있다.

하악 이부확장 시 하악골 이동 양상과 응력 분포에 관한 삼차원 유한요소법적 연구

이도훈,홍현실,채종문,조진형,김상철 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.1

하악 이부확장에서 골 절단선의 위치 및 종류와 견인 장치의 종류에 따른 차이를 알아보고자 삼차원 유한요소법으로 하악골의 이동 양상 및 응력 분포를 조사하였다. 골 견인장치의 종류로는 치아 의존형과 골 의존형, 혼합형, 30˚ 기울여 위치한 치아 의존형의 4가지를, 골절단 위치와 방법으로 하악 중절치 간 수직절단과 하악 정중이부를 관통하는 계단식 골절단 등의 2가지를 설정하였다. 연구 결과, 골절단의 위치 및 방법과 견인장치의 종류에 관계없이 과두를 포함한 하악골의 모든 부위에서 외측방 변위를 보였으며 상하적이나 전후방적 변위는 적은 양이었으나 방향에 있어 군간에 차이를 보였다. 치아 의존형 장치에 의한 골절단면 이개 양태는 V형이었으나 골 의존형 장치는 역V형이고 혼합형 장치는 평행하게 확장되었다. 골 의존형 장치에 의한 하악각의 외측 변위량이 다른 장치에 비해 컸다. 30˚ 기울여 위치한 치아 의존형에서의 변위는 측방적, 전후방적 면에서 좌우 차이가 인정되었다. Objective: The objective of this study was to evaluate the displacement pattern and the stress distribution of the finite element model 3-D visualization during symphyseal widening according to the osteotomy position, osteotomy type, and distraction device. Methods: The kinds of distraction devices used were tooth-borne type, hybrid type, bone-borne type and tooth-borne type 30˚ angulated, and the kinds of osteotomy design were vertical osteotomy line between the central incisors and step osteotomy line through the symphysis. Results: All reference points of the mandible including the condyles were displaced laterally irrespective of the osteotomy position, osteotomy method and distraction device. The anteroposterior or vertical displacements showed small differences between the groups. The widening pattern of the osteotomy line in the tooth-borne type of device was v shaped, and that of bone-borne type was a reverse v shape. However, the pattern in the hybrid type was parallel. The lateral displacement of the mandibular angle by the bone-borne device was more remarkable than the other types of devices. The displacement by the 30˚ angulated tooth-borne type was different between the left and right sides in both the transverse and anteroposterior aspects. Conclusion: The design of the distraction devices and osteotomy line can influence the displacement pattern and the stress distribution during mandibular symphyseal distraction osteogenesis procedures.

역형성 핍지교세포종의 임상 분석에 대한 연구

이현성,최우진,고영초,이채혁,박효일 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives : In this study, the author reviewed the clinical features of the patients with anaplastic oligodendroglioma and evaluated the efficacy of surgery, radiation therapy and chemotherapy as a treatment modality. The study was intended to provide the standardized treatment option for this rare disease. Methods : The author present ten cases of pathologically proven anaplastic oligodendrogliomas from 1988 to 2002. A retrospective analysis of clinical presentation. radiological and pathological features, and the effectiveness of treatment was performed and the factors affecting prognosis were investigated. Fesults : The ten patients comprised of four males and six females. The mean age at diagnosis was 34.4 (8-70). The mean follow-up duration was 40.5 months. and two patents died of tumor progression during the follow-up(70, 86 months, respectively). The most common presenting symptom was seizure(70%). All patients underwent surgery and the tumors were removed as much as possible. Postoperatively, Radiation therapy was applied to seven patients. and PCV(procarbazine CCNU-vincristine) based chemotherapeutic agent was administered to five patients. Total removal was achieved in five cases and subtotal removal was possible in the rest. In the group with PCV therapy, complete remission was observed in two, partial remission, stable disease, and disease progression to death in one, respectively. The patients well tolerated the toxicity of chemotherapy. During the follow-up, tumor recurrences were observed in four patients, and they were treated with additional operations and/or chemotherapy. Mixed anaplastic oligoastrocytoma showed earlier recurrence than anaplastic oligodendrogliomas in this study(P=0.014), but the other clinical factors and treatment modalities were not related to the time of recurrence of the tumor. Conclusions : In this study, the authors confirmed the good response of postoperative radiological treatment and chemotherapy in patients with anaplastic oligodendroglioma. PCV chemotherapy should be considered as primary treatment method for the patients with anaplastic oligodendroglioma.

한국개비자(Cephalotaxus koreana)의 Harringtonine 과 Homoharringtonine에 관한 연구

이연,박두천,박호일,주우홍,이현채,신동수 昌原大學校 基礎科學硏究所 1996 基礎科學硏究所論文集 Vol.8 No.-

한국산 개비자로부터 alkaloid계통의 성분인 harringtonine과 homoharringtonine의 혼합물을 추출하여 한국산 개비자의 잎, 줄기, 뿌리에서의 harringtonine과 homoharringtonine의 함량은 고속 액체 크래마토그래피에 의해 결정하였다. 두물질의 함량은 서식지, 식물의 부위에 따라 상이하였다. Harringtonine의 함량은 줄기보다 잎과 뿌리에서 높았고, homoharringtonine의 함량은 harringtonin 함량보다 낮았다. 팔공산, 덕유산, 백양산, 지리산 및 남해에서의 잎의 homoharringtonine 함량은 줄기와 뿌리에서 높게 나왔으며, 조계산과 진도에서는 잎의 함량이 뿌리와 줄기에서 보다 낮았다. Harringtonine and homoharringtonine known as anti-cancer agents were isolated from Korean native plumyew (Cephalotaxus koreana). The contents of harringtonine and homoharringtonine in the needles, stems, and roots of Korean native plumyew were determined by high performance liquid chromatography (HPLC). The contents of both compounds varied with the site of location and the part of plant. The content of harringtonine was higher in needles and roots than in stems, whereas the content of homoharringtonine was lower than harringtonine. Homoharringtonine contents in needles at Mt. Palgong, Mt. Dukyu, Mt. Baekyang, Mt. Jiri, and Namhae were higher than in stems and roots. But homoharringtonine contents in needles at Mt. Jokye and Jindo were lower than in stems and roots.

인체의 수동적 전기특성 계측법 개발

이현철,윤재현,박형준 원광대학교 공업기술개발연구소 2003 工業技術開發硏究誌 Vol.23 No.-

In this study, a system for the method measuring of passive electrical properties in the human body was developed. The system was composed of the stimulating part for input with voltage(about 2[㎷]) and of the measuring part for measurement of electrical properties in human body. As a result of this experiment, the frequency characteristic of each subject represent that the electrical properties goes up in spite of a constant stimulate-voltage according to frequency (l[㎐]-50[㎑]) increment. Namely, the amplitude of stimulate-signal was not reflected but frequency was reflected on the measured results. This result be estimated that the proposed system is able to measure the passive electrical properties of human body. Also, it would be estimated neural signal propagation directions by using the method developed in this study was measured passive electrical properties in each part of body.

日本 價格破壞 |店의 營體系에 關한 硏究

채희용 ; 이현기 김천대학교 1998 김천대학교 논문집 Vol.19 No.-

In 1990's, it is often supposed that the new trend of various distribution business is price destruction. The meaning of price destruction, here is not a price sale selling a discounted material during regular terms but the form of selling as a dramatically discounted price everyday and no holiday. Such new store types as discount stores of price destruction have begun to appear in Korean retailing market since November 1993. Since then, they have been growing very rapidly. Having led by a few department stores, supermarkets and conventional markets, the domestic retail arena met a meaningful turning-point with the rising number of discount stores. Cashing on their cutting edge. "so-good' price, to the extent of destructing the existing price structure and marketing structure as well, the discount stores are forecast to gain a rapid growth in coming years, leading the distribution industry expansion. This study focuses on the "low-cost operations” since the factor is the very reason for the creation and survival of discount stores and plays a decisive role in their success and failure. The competitiveness of discount stores will depend on how they effectively combine the low-cost operations and the marketing strategies, and give much satisfaction to consumers. The domestic retail picture will be re-drawn by a few strong play living up to these qualifications.