브루셀라균에 노출된 미생물 검사실 직원들에 대한 예방적 항생제 요법과 혈청학적 추적검사

이창섭,이혜수,이재현,박진희,최영실,황규잠,이흥범 대한감염학회 2008 감염과 화학요법 Vol.40 No.2

The aerozolization is one of possible Brucella transmission mechanisms, particularly in air-borne exposed laboratory workers. In this study, seven laboratory workers were potentially exposed to B. abortus via aerosols. Two laboratory workers who sniffed an agar plate several times were considered to be at high risk for acquiring the disease, 5 workers who did not work directly with the strain were be considered at low risk of infection. Prophylactic antibiotics of doxycycline 200 mg/day and rifampin 600 mg/day were offered for 6 weeks in high risk workers and 3 weeks for low risk workers respectively. Enrolled workers were advised to check for serological testing of Brucella species every 3 weeks during a total period of 12 weeks. Compliance with taking medicine was 57.1% (4/7) and compliance for completing the serological tests was 85.7% (6/7). None of the laboratory workers developed clinical disease or tested positive serologically during 3 months of seroloaical testing and 1 year of clinical follow-up.

Construction of L - Threonine Overproducing Escherichia coli by Cloning of the Threonine Operon

LEE,JIN - HO,JONG - WON OH,KAP - SOO NOH,HYUNE - HWAN LEE,JAE - HEUNG LEE 한국미생물생명공학회 1992 Journal of Microbiology and Biotechnology Vol.2 No.4

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

濟州道 住民 蟯蟲感染의 疫學的 硏究

李根泰,李範珪,盧英俊,任世旭,李在興 醫藥係社 1955 綜合 醫學 Vol.12 No.12

노동법제정의 특징과 전진한의 역할

이흥재 ( Heung Jae Lee ) 서울대학교 법학연구소 2009 서울대학교 법학 Vol.50 No.4

This article primarily attempts to clarify the key role of Jin Han Jeon, a member of the Second National Assembly(SNA) in the establishment of four labor relations laws(the Labor Union Act, the Labor Dispute Adjustment Act, the Labor Relations Commission Act, and the Labour Standard Act: labor law, from now on) during a national emergency, the Korean War, at the refuge capital Pusan in 1953. In addition, it is argued that labor law was enacted with its own unique characteristics on the basis of systematic debate in SNA, despite the turmoil of the Korean War, on the contrary to the existing opinion that it was a product of a hasty and near exact copy of foreign law, as drafted by the Government. Accordingly, the subject and range of this study are examining the interrelationship between the role played by Jin Han Jeon and the characteristic of labor law establishment with respect to the legislative (1) background and purpose, (2) process, and (3) substance by mainly analyzing the stenographic record of SNA. Firstly, it should be noted that the background of labor law establishment was so called Political Upheaval of Pusan(namely, the Selected Amendment to the Constitution) and the collective actions of the Cho-Bang(cotton spinning factory) during the Korean War. The cruel crackdown on labor disputes and on Jin Han Jeon had been made in the collective actions of the Cho-Bang under President Seung Man Lee`s regime. Under the politically harsh circumstances, Jin Han Jeon made a significant contribution to establish a foundation of labor law in Korea. Specifically, he played a key role to lay a bill of labor law before the SNA in 1953 in advance of any other agenda as well as bring the distinctive revised bill to ensure the freedom of collective action. Jin Han Jeon thus made it clear that the purpose of labor law was to establish a legal basis of labor movement, anchored in his own experience, whereby ensuring the fundamental labor rights guaranteed by the Constitution. Secondly, it is considered as a unique characteristic of the process on the labor law establishment that the law-makers from Korea Labor Union Confederation played leading roles in legislation. Following the Original Bill(OB) drafted by Social Health Committee of the SNA, the various Revised Bill(RB)s were brought mainly by Jin Han Jeon as well as some other members of SNA. The consideration and debate on the bills focused for the most part on RBs due to intense contemplation of the members of SNA in order to enact better legislation than OB. Finally, it should not be underestimated that the unique characteristic on the substance of labor law. For instance, the Labor Relations Commission Act was a distinctive legislation, unlike the Japanese labor law at that time. The right to political activity of labor union, right to national strike, and the requirement of just causes on dismissal under the Labor Standard Act were the unique features as well. The labor law establishment was a fruit of continuous labor movement since the Liberation of 1945 in order to realize the fundamental labor rights, despite the political suppression on labor movement under Seung Man Lee`s regime. The existing opinion that labor law was passed as drafted by the Government and as a near copy of foreign law should thus be rectified. It might hence be concluded that the inseparable interrelation between the labor law establishment in 1953 and the unique role played by Jin Han Jeon in the SNA for the legislation was the most important characteristic of establishing the labor law.

GC-ECD를 이용한 유기염소계 및 Pyrethroid계 농약 동시 분석법

김우성,이선화,김재이,정지윤,이명자,박영채,이영자,정성욱,이봉헌,박흥재 한국환경과학회 2003 한국환경과학회지 Vol.12 No.4

Pesticides were extracted from samples with 70% acetone and methylene chloride in order, and then cleaned up via open-column chromatography apparatus packed with florisil, and finally analyzed simultaneously the organochlorine and pyrethroid pesticides using GC(ECD). An ultra-2 fused silica capillary column was used to separate and identify the products. The resolution between the last isomeric peak of cypermethrin(59.987min) and the first isomeric peak of flucythrinate(60.043min) was not satisfactory. The last isomeric peak of fenvalerate(62.344min) and the first isomeric peak of fluvalinate(62.397min) were overlapped. Recoveries of soybean sample for the most pesticides were 73.3% to 102.4%. Detection limits were between 0.004 and 0.063 ㎍/㎎ when this method was used.

GC/NPD를 이용한 다성분 잔류농약의 동시분석

김우성,이선화,김상엽,정동윤,김재이,이영자,이홍재,정성욱,박흥재 한국환경과학회 2003 한국환경과학회지 Vol.12 No.10

Pesticides were extracted from samples with 70% acetone and methylene chloride in order, and then cleaned up via open-column chromatography apparatus packed with fiorisil, and finally analyzed simultaneously the organophosphorus pesticides using GC/NPD, Ultra-2 and Ultra-1 fused silica capillary columns were used to separate and identify the products. Recovery of most analytes from soybean sample, taken from pesticide residues well, was greater than(80%) for all except(6) analytes. This method can simultaneously determine multiple pesticides with a high degree of accuracy and precision.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

물 및 디메틸포름아마이드中에서 4-(2-Pyridylazo)-resorcinol의 分光電氣化學的 環元

李興洛,裵俊雄,李在鶴,吳相協 慶北大學校 1988 論文集 Vol.45 No.-

Spectroelectrochemistry involve the combination of an electrochemical technique with a spectroscopic techinque so that the two measurements may be performed simultaneously in an electrochemical cell. One of the most generally useful spectroelectrochemical technique involves spectral observation of a thin layer of solution. Thin-layer spectroelectrochemistry at the optically transparent thin-layer electrode(OTTLE) takes advantage of the rapid electrolysis (30∼60 sec.) and small volume features of thin-layer electrochemistry. This study has used controlled potential as the excitation signal. Potential control provides a facile means of presicely adjusting the redox potential of the thin solution layer as determined by the Nernst equation for reversible systems: E_applied=E^0'+0.059/n log (O)/(R) In experiment, the slopes of Nernstian plot were 28.3mV in aqeous solution and 53mV in N, N-dimethylformamide(DMF) solution. The results of this study showed that the reduction mechanisms of 4-(2-pyridylazo)-resorcinol(PAR) were one two-electron step in aqueous solution and two one-electrons steps in DMF solution. The formal reduction potentials(E^0') of the PAR were -0.574 volts vs. S.C.E. in aqueous soltion and -0.74 volts vs. Ag/AgClO_4 in DMF solution. These results were generally similar to the reduction mechanism of the other cyclic hydrocarbons in the aprotic solvent. In aprotic solvent, the product of the first electron transfer is expected to be a relatively stable anion radical. In this experiment tetraethylammonium perchlorate was used as a supporting electrolyte of the DMF solution.

하악 중절치에 발생한 치내치

이정진,최병재,이제호,최형준,손흥규,김성오 大韓小兒齒科學會 2008 대한소아치과학회지 Vol.35 No.2

치내치(dens invaginatus)는 형태분화기에 비정상적인 치아발생이 원인으로 경조직이 석회화되기 전에 법랑질 상피가 함입되어 생기는 드문 치아 기형이다. 치내치의 발생 빈도는 0.04-10%이고 대부분이 상악에서 발생하며 특히 상악 측절치에서의 빈도가 높고 하악에서는 드물게 발생한다고 보고되었다. 치내치는 우상치나 왜소치,쌍생치,과잉치,상아질 형성부전증과 같은 형태 이상과 연관되어서 나타나는 경우도 있다. 치내치는 함입된 정도에 따라 3가지로 분류할 수 있고 다양한 해부학적 변이를 보이며,이러한 기형은 미생물의 침입을 용이하게 하므로 치아우식증과 치수감염 및 괴사의 위험성을 높인다. 치수조직에 문제가 생긴 경우 근관의 복잡한 해부학적 형태 때문에 근관치료가 매우 어려우므로 조기에 진단하여 치료하는 것이 중요하다. 본 증례들은 하악 중절치에 드물게 발생하는 치내치를 가진 환아에 대한 것으로 하악 중절치에서의 치내치 유병율과 치료에 대한 고찰을 하였기에 이를 보고하는 바이다. Dens invaginatus is a rare malformation resulting from invagination of the enamel before calcification has occurred. It is mostly found in permanent maxillary lateral incisors and mandibular teeth are rarely affected by this anomaly. The malformation is estimated to affect between 0.04 % and 10 % of people and has been associated with other abnormalities such as taurodontism, microdontia, gemination and dentinogenesis imperfects. Dens invaginatus is classified in three types with respect to the depth of invaginatus and has a broad spectrum of morphologic variations. Invagination frequently allows the entry of irritants and microorganism, which usually lead to caries, pulp infection and pulp necrosis. Root canal treatment on such invaginatus tooth may present severe problems because of its complex anatomy of the tooth. Therefore, the early diagnosis of such malformation is crucial and preventive approach is strongly recommended.