PC 상에서 On-line 한글 인식에 관한 연구

이재도,양승복,정수웅 대구보건대학 1994 대구보건대학 論文集 Vol.14 No.-

In this paper, Using a Fuzzy theory an On-Line phoneme recognition procedure of Korean characters is studied. The recognition method is performed by reading the pixel coordinates, finding the feature points, recognizing the stroke, recognizing the phoneme in order. In the course of recognizing the stroke, first the feature points of an inputed stroke is characterized by starting point, end point, and bending point. and then, based on 0, 5, 6, 7, 8, 9, and 10 stroke code among the recognized stroke the distance or direction between base stroke and the next input stroke is used for recognizing the phoneme

부분 무치악 환자에서 마그네슘 이온주입 임플란트의 성공률에 대한 전향적 임상연구

최수정,유정호,이규복,김진욱 大韓齒科補綴學會 2012 대한치과보철학회지 Vol.50 No.3

Purpose: This study examined the clinical success rate of Mg titanate implants (M Implant system, Shinhung, Korea), which employ a Mg coating method, by evaluating the marginal bone loss and implant stability using radiographs and Osstell, over a 1 year. Materials and methods: The locations of the implants placement were divided into 4 areas; the maxillary and mandibular premolars and molars. In the maxilla, 8 and 9 implants were inserted in the premolar and molar areas, respectively. In the mandible, 11 and 51 implants were inserted in the premolar and molar areas. Marginal bone loss and ISQ of all implants (79) were measured after insertion, mounting the prosthetic appliance, and 1, 3, 6, and 12 months after loading. The marginal bone loss was measured from the radiograph using XCP bite, which was customized, and the implant stability measured using Osstell. Fisher's exact test (α=.05) was used to compare the success rates of each region. Results: The mean marginal bone loss for the upper and lower jaws were 1.537 mm and 1.172 mm. The mobility showed a non-significant reduction or increase according with time. The success rates were accounted for 94.12% and 98.39% in the upper and lower jaws; the premolars and molars were accounted for 100% and 96.67%. The two cases of early failure resulted from failure of primary stability during implant insertion. The late failures were not observed for 1 year after adding a loading to the implants. Conclusion: The Mg titanate implant showed good primary stability and good clinical results in both healing and function. 연구 목적: 부분 무치악 환자에서 Mg titanate implant (M Implant system, Shinhung, Korea)의 보철후 1년간의 방사선사진을 이용한 변연골 흡수량과 Osstell을 이용한 임플란트 안정성 평가 결과를 분석하여 임상적인 성공률에 대해 알아보고자 한다. 연구 재료 및 방법: 38명의 환자에 79개의 임플란트를 식립하여 보철 후 1년 동안 변연골 흡수량, 임플란트의 동요도, 임플란트 식립 위치에 따른 분포 및 성공률, 보철 전후에 따른 성공률을 분석했다. 결과: 변연골의 흡수량은 보철물 장착 후 1년간의 평가에서 상악에서는 평균 1.537 mm, 하악에서는 평균 1.172 mm의 변연골 흡수가 관찰되었으며, 전체적인 상하악의 평균 변연골 흡수량은 1.255 mm로 관찰되었다. 수술 후 시간이 경과함에 따라 ISQ값은 미약하게 감소하였다가 증가하는 경향을 보였으나, 상악과 하악 모두에서 식립 당일 이후 예비 인상일, 최종 보철물의 장착일과 주기적인 평가 기간 동안 ISQ값의 큰 증가나 감소를 나타내지는 않았다. 성공률은 상악에서의 94.12%였고, 하악에서의 98.39%였다. 결론: 본 실험의 결과로 미루어 Mg titanate implant는 임상적으로 양호한 결과를 보여주었다.

그란닥신 정(토피소팜 50mg)에 대한 토핌 정의 생물학적 동등성

조혜영,정현철,허수희,임동구,문재동,이용복 한국약제학회 2001 Journal of Pharmaceutical Investigation Vol.31 No.2

Tofisopam is a new type of tranquilizer valuable for the relief of anxiety and tension in a wide range of emotional disorders. Tofisopam has the therapeutic characteristics of a minor tranquilzer and a mild stimulatory effect. The purpose of the present study was to evaluate the bioequivalence of two tofisopam tablets, Grandaxin^TM (Hwan In Pharmaceutical Co., Ltd.) and Tofim^TM (Kyung Dong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Eighteen normal male volunteers, 23.11±2.83 years in age and 65.43±7.64 kg in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After one tablet containing 50 mg of tofisopam was orally administered, blood was taken at predetermined time intervals and the concentrations of tofisopam in serum were determined using HPLC method with UV detector. The pharmacokinetic parameters such as AUC_t C_max and T_max were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC_t C_max and T_max between two tablets based on the Grandaxin^TM were -5.59%, 2.22% and -13.18%, respectively. Minimum detectable differences (Δ) at α=0.10 and 1-β=0.8 were less than 20% (e.g., 14.95% and 19.34% for AUC_t and C_max respectively). The powers (1-β) at α=0.10, Δ=0.2 for AUC_t and C_max were 95.21% and 81.93%, respectively. The 90% confidence intervals were within ±20% (e.g., -15.64∼4.45 and -10.77∼15.21 for AUC_t and C_max respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Tofim^TM tablet is bioequivalent to Grandaxin^TM tablet.

유비쿼티스 센서 네트웨크에서의 저전력 상호인증 프로토클

조영복,정윤수,김동명,이상호,Cho Young-Bok,Jung Youn-Su,Kim Dong-Myung,Lee Sang-Ho 한국컴퓨터정보학회 2005 韓國컴퓨터情報學會論文誌 Vol.10 No.2

유비쿼터스 센서 네트워크에서 모든 센서노드들은 한정된 배터리로 통신에 참여하게 된다 기존의 인증방식을 사용하는 경우 많은 연산 수행이 필요하여 센서노드의 배터리를 과다하게 소모하여 센서노드의 동작 기간이 상대적으로 짧아지므로 네트워크 유지에 많은 어려움이 존재한다. 이 논문에서는 센서노드의 인증과정에서 전력 소비문제를 해견하기 위해 RM (RegisterManager)과 AM (AuthenticationManager)을 도입한 네트워크 구조를 제시하고, 노드의 상호인증을 통한 세션키를 발급하는 저전력 상호인증 프로토콜을 제안한다. RM과 AM은 개댈 센서노드에서 안전성을 보장하기 위해 수행되는 키 생성 및 암/복호화, 인증 과정을 센서노드 대신 처리하여 빠른 연산속도로 알고리즘을 처리한다. 따라서 센서노드의 인증에 소요되는 알고리즘 수행시간이 동일 서브넷에 존재하는 경우 평균 2.96$\%$, 서로 다른 서브넷에 존재하는 경우 평균 12.91$\%$ 빠르게 수행된다. 따라서 제안 방식은 센서 노드가 더 오랜 시간 통신에 참여할 수 있도록 하며, 센서네트워크의 크기가 증가할수록 효율적이다. All sensors in Ubiquitous sensor network have to communicate with limited battery If we adopt current authentication, there are difficulties to keep sensor network because heavy calculation in each sensor needs more power and lifetime of sensor could be short relatively because of the effect. This paper suggests network structure which is using RM(RegisterManarer) and AM(AuthenticationManager) to solve power Problem on authentication, and su99ests mutual-authentication protocol with low Power which supports a session key by mutual-authentication. RM and AM manage algorithm with fast calculation to keep the safety by doing key generation. encryption/decryption. authentication instead of each sensor node . Processing time to authenticate sensor node is 2.96$\%$ fast in the same subnet, and 12.91$\%$ fast in different subnet. Therefore. the suggested way Provides expanded lifetime of censor node and is more effective as sensor network size is bigger and bigger.

그란닥신 정(토피소팜 50 mg)에 대한 토핌 정의 생물학적 동등성

조혜영,정현철,허수희,임동구,문재동,이용복 전남대학교 약품개발연구소 2001 약품개발연구지 Vol.10 No.-

Tofisopam is a new type of tranquilizer valuable for the relief of anxiety and tension in a wide range of emotional disorders. Tofisopam has the therapeutic characteristics of a minor tranquilzer and a mild stimulatory effect. The purpose of the present study was to evaluate the bioequivalence of two tofisopam tablets, Grandaxin^TM (Hwan In Pharmaceutical Co., Ltd.) and Tofim^TM (Kyung Dong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Eighteen normal male volunteers, 23.11±2.83 years in age and 65.43±7.64㎏ in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 50㎎ of tofisopam was orally administered, blood was taken at predetermined time intervals and the concentrations of tofisopam in serum were determined using HPLC method with UV detector. The pharmacokinetic parameters such as AUC_t, C_max and T_max were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC_t, C_max and T_max between two tablets based on the Grandaxin^TM were -5.59%, 2.22% and -13.18%, respectively. Minimum detectable differences (Δ) at α=0.10 and 1-β=0.8 were less than 20% (e.g., 14.95% and 19.34% for AUC_t and C_max, respectively). The powers (1-β) at α=0.10, Δ=0.2 for AUC_t and C_max were 95.21% and 81.93%, respectively. The 90% confidence intervals were within ±20% (e.g., -15.64∼4.45 and -10.77∼-15.21 for AUC_t, and C_max, respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Tofim^TM tablet is bioequivalent to Grandaxin^TM tablet.

남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

Characteristics of Lightning Overvoltages Coming in Low-Voltage Power Distribution Systems

Lee, Bok-Hee,Lee, Dong-Moon,Lee, Su-Bong,Jeong, Dong-Cheol,Lee, Jae-Bok,Myung, Sung-Ho The Korean Institute of Electrical Engineers 2003 KIEE International Transactions on Electrophysics Vol.3C No.3

The importance of improving the quality of electric power is being strongly raised, owing to an increasing use of sensitive and small-sized electronic devices and systems. The transient over-voltages on low-voltage power distribution systems are induced by direct or indirect lightning return strokes. These can cause damage and/or malfunction of the utility systems for home automation, office automation, factory automation, medical automation, etc. The behaviors of lightning overvoltages transferred through the transformer to the low-voltage distribution systems using a Marx generator were experimentally investigated. Furthermore, the coupling mechanisms of lightning overvoltages transferred to the low-voltage systems were clearly illustrated through a theoretical simulation using a Pspice program. The overvoltages in low-voltage ac power systems are rarely limited by the application of the surge arrester to the primary side of the distribution transformer. A superior surge protection scheme is to install surge protection devices at the service entrance switchboard and/or at the load devices in TN power systems.

Characteristics of Lightning Overvoltages Coming in Low-Voltage Power Distribution Systems

Bok-Hee Lee,Dong-Moon Lee,Su-Bong Lee,Dong-Cheol Jeong,Jae-Bok Lee,Sung-Ho Myung 대한전기학회 2003 KIEE International Transactions on Electrophysics Vol.3C No.3

Neurite Outgrowth on Nanocomposite Scaffolds Synthesized from PLGA and Carboxylated Carbon Nanotubes

Lee, Hyun Jung,Yoon, Ok Ja,Kim, Do Hee,Jang, Yeong Mi,Kim, Hyun Woo,Lee, Won Bok,Lee, Nae-Eung,Kim, Sung Su WILEY-VCH Verlag 2009 Advanced engineering materials Vol.11 No.12

<P>Carbon nanotubes (CNTs) have been suggested as suitable materials for biomedical applications, especially in the neural area. It is essential not only to investigate the biocompatibility of CNTs with the neural system but also to determine proper methods for applying CNTs to neuronal growth. This work represents the first application of CNTs by electrospun poly(D,L-lactic-co-glycolic acid) (PLGA) scaffolds for a neural system. We synthesized electrospun nanocomposites of PLGA and single-walled carbon nanotubes functionalized by carboxylic acid groups (c-SWNTs), and investigated neurite outgrowth from SH-SY5Y cells on these nanocomposites as compared to that on fibrous PLGA alone. Cells on our PLGA/c-SWNT nanocomposite showed significantly enhanced mitochondrial function and neurite outgrowth compared to cells on PLGA alone. We concluded that c-SWNTs incorporated into fibrous PLGA scaffolds exerted a positive role on the health of neural cells.</P> <B>Graphic Abstract</B> <P>Carbon nanotubes (CNTs) have distinctive characteristics such as high conductivity which could help the promotion of neuronal function. Electrospun nanocomposites of poly(D,L-lactic-co-glycolic acid) (PLGA) and CNTs were synthesized, and neurite outgrowth and mitochondrial function of human neuroblastoma cells were investigated on these nanocomposites and compared with that on fibrous PLGA alone. The results showed that CNTs incorporated into fibrous PLGA scaffolds exerted a positive role on the health of neural cells. <img src='wiley_img_2010/14381656-2009-11-12-ADEM200900144-content.gif' alt='wiley_img_2010/14381656-2009-11-12-ADEM200900144-content'> </P>

임상 검체에서 분리된 nontyphoid Salmonella에서의 integron의 빈도와 특징

이정은,박수진,김성한,김미나,이남용,이복권,이상오,김양수,우준희,최상호 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

Background : Nontyphoid Salmonella (NTS) is a leading cause of human food-borne enteritis, It has been known that integron, a naturally occurring gene capture and expression element, Plays an important role in the development and dissemination of multidrug-resistance. In this study, we investigated the prevalences and molecular characteristics of integrons in NTS clinical strains. Materials and Methods : Between 1995-96 and 2000-03, a total 261 NTS clinical strains comprising 39 serotypes were collected from clinical specimens. All strains were serotyped, and the MICs of ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, tetracycline, and trimethoprim were determined by agar dilution method. Integrons were detected by PCR amplification of integrase genes, and gene cassettes were determined by PCR and sequencing, Conjugation experiments were performed using E. coli J53 as a recipient. The clonal relationship was analyzed by pulsed-field gel electrophoresls (PFGE). Results : Of the 261 strains tested, class 1 integrons were present in 21 strains (8.0%). Class 2 and class 3 integrons were not found. The integron-positive rate was higher in S. Typhimurium (24.2% [8/33]) than in S. Enteritidis (2.0% [3/153]). Overall rates of antimicrobial resistance were higher in integron-positive strains. dhfr12-orfF-aadA2gene cassette was detected in 5 strains, aadA2in 4 strains, dhfr17-orfF-aadA5 in 2 strains, and addA1 in 1 strain. Ten integron-positive transconjugants were successfully selected. Among 8 integron-positive strains of S. Typhimurium, 7 had similar PFGE patterns. Conclusion: This study suggests that integrons are already playing a significant role in antimicrobial resistance in NTS. Continuous monitoring is needed to detect the emergence and spread of integron-mediated antimicrobial resistance.