제71차 대한 결핵 및 호흡기학회 추계학술대회 : 일반연제 발표 ; T-Cell Clone을 이용한 결핵균 항원의 분석

임동균,서주영,박정규,황응수,국윤호,차창룡 대한결핵 및 호흡기학회 1990 Tuberculosis and Respiratory Diseases Vol.37 No.4

A Study on the Operational Efficiency of Safety Experience Center for Improving Students' Safety Awareness

임동균 (사)위기관리이론과실천 2023 Journal of Safety and Crisis Management Vol.13 No.6

Since the establishment of the government, large-scale safety accidents have continued to occur and human and material damage has increased. The responsibility is not only the responsibility of some specific organizations such as the state or local governments. In order to prevent such accidents, not only the nation but also the people should be interested in safety education, protect themselves, and feel a sense of responsibility for safety in a social sense. Safety education should naturally permeate into daily life. However, it is also true that there is still a public opinion that recognizes the efforts and costs of safety education as an economic burden. Therefore, by activating the safety experience center, it is necessary to correct the unreasonable perception of accumulated safety throughout the nation and society so that the people can enjoy a safe and comfortable life. In this study, the activation plan of the safety experience center was examined using FGI survey and AHP analysis technique to activate the safety experience center.

Combined Effect of Irradiation and Ageing Condition on Physicochemical and Microbial Quality of Hanwoo Eye of Round

임동균,조철훈,김현주,차주수,김현철,남기창 한국축산식품학회 2015 한국축산식품학회지 Vol.35 No.3

The combined effects of electron-beam irradiation and ageing of beef were examined. The irradiated samples at dose of 0 or 2 kGy were kept and analyzed for the microbial growth, shear values, meat color, and nucleotide-related flavor compounds at different ageing temperatures (2, 10, or 25°C) for 8 d. The irradiation effect on inactivation of foodborne pathogens was also investigated. The population of Listeria monocytogenes and E. coli O157:H7 inoculated in beef samples decreased in proportion to the irradiation dose, showing D10 values of 0.66 and 0.65 kGy respectively. The irradiated beef eye of round had lower number of total aerobic bacteria (TAB) than non- irradiated one during the storage, but the TAB increased with higher ageing temperature (p<0.05). Especially, TAB increased sharply in non-irradiated samples aged at 25°C after 4 d (p<0.05). With increasing ageing temperature and ageing time, shear force values decreased (p<0.05). The color a* values of the irradiated beef were lower than those of the non-irradiated throughout the ageing period (p<0.05). As ageing time and temperature increased, the amounts of inosine monophosphate decreased and the hypoxanthine increased (p<0.05). Relatively high ageing temperature could be used at irradiated beef eye of round to shorten the ageing time.

사람에서의 MERS 면역반응 연구 동향

임동균 대한인수공통전염병학회 2019 창립총회 및 학술대회 초록집 Vol.2019 No.1

신종 바이러스 감염증에 대한 효과적인 치료, 진단 및 예방법 개발을 위해서는 발병기전 및 인체 면역반응에 대한 정보가 필수적이다. 2015년 국내에서 발생한 메르스 감염증 환자의 각종 면역반응을 분석하여 인체 면역반응이 메르스 병인 및 숙주 방어에 미치는 영향을 알아보고자 하였다. 이를 위해 발병 초기 및 회복기 혈액검체를 대상으로 각종 사이토카인의 농도, 항바이러스 항체 역가 및 바이러스 항원 특이 T-림프구 반응성 등을 관찰하고 임상경과 및 중증도와 이들 측정치와의 관련성을 조사하였다. 발병초기 혈장내 proinflammatory cytokine 및 chemokine들이 임상 중증도와 비례적으로 높게 관찰되었으며 일부 중증환자에서는 CD8+ T-림프구 반응이 강하게 관찰되어 이러한 과도한 면역반응들이 조직병변 유발과 관련될 수 있음을 시사하였다. 항체반응은 발병 2-3주째 나타나기 시작하여 3-4주째 최고치에 이른 후 점차 낮아지지만, 회복 후 3년째에도 약 45%의 환자에서 양성반응이 관찰되었다. 임상경과가 중증일수록 중화항체반응이 높게 나타나지만 이러한 항체반응이 반드시 증세 호전이나 바이러스 퇴치를 불러 오지는 못하는 것으로 추정된다. 세포성 면역반응은 Th1 또는 Tc1 반응 위주이며, 이 역시 중증일수록 강한 반응성을 보이고 오랫동안 지속성을 나타내는 것으로 관찰되었다. CD4+ T-림프구는 S-protein 보다 E/M/N-protein에 더 높게, 반대로 CD8+ T-림프구는 S-protein에 더 높게 반응하는 것으로 조사되었다. 세포성 면역반응 추적조사 결과, 메르스 회복환자의 45-50%에서 감염 후 36개월까지 memory T 림프구가 관찰되었으며, CD4+ T-림프구 보다 CD8+ T-림프구에서 더 높은 빈도로 나타났다. 이와 같이 메르스 감염에 따른 기본 면역정보들의 확보에도 불구하고, 새로운 MERS 면역치료제 및 예방백신의 개발을 위해서는 초기 면역반응의 면역병리기전에서의 정확한 역할이나 상기 관찰된 기억면역반응들의 실질적 질병예방 능력에 대해서 보다 심도있는 추후 연구가 필요할 것이다.

Effect of natural antioxidant extracted from Citrus junos seib. or Prunus mume. on the quality traits of sun-dried Hanwoo beef jerky

임동균,김종주,서강석,남기창 충남대학교 농업과학연구소 2012 농업과학연구 Vol.39 No.2

The objective of the study was to evaluate the quality characteristics of sun-dried Hanwoo beef jerky added with the extract of Citrus junos seib. or Prunus mume. Hanwoo beef shank muscles were sliced, marinated, and sun-dried at 25°C, relative humidity of 35%. The physicochemical quality and microbiological safety of the Hanwoo beef jerky aerobically packaged were analyzed during the storage of 25°C. The moisture content of beef jerky with Citrus junos seib. was the lowest among the treatments after 20 d. Citrus junos seib. and Prunus mume jerky after 10 d had significantly lower aw than those after 0 and 20 d (p<0.05). The pH values of jerky generally ranged from 5.76 to 5.84. The pH value of Prunus mume jerky was significantly higher than those of other jerky samples (p<0.05). Prunus mume jerky showed significantly lower TBARS value than the others after 20 d (p<0.05). Citrus junos seib. jerky showed a significantly lower lightness (L*), redness (a*) and yellowness (b*) than the others during the storage (p<0.05). Prunus mume samples after 10 d had significantly higher L*, a*, and b* values than the others (p<0.05). With regard to sensory properties,Citrus junos seib. and Prunus mume jerky showed significantly higher flavor and overall acceptability scores than the control (p<0.05). The extracts of Prunus mume will be used in sun-dried Hanwoo beef jerky as a natural agent to retard lipid oxidation and to improve meat color.

Quantitative Analysis of Central Nervous System Tissues (CNST) in Beef By-Products in Retail Market

임동균,이무하 한국축산식품학회 2012 한국축산식품학회지 Vol.32 No.2

This study was carried out to investigate the applicability of the detection of central nervous system tissues (CNST) in beef by-products in retail market. Beef by-products including large intestine, brain, spinal cord, liver, lung, spleen and heart were purchased and tested for the presence of CNST using an ELISA method. The ELISA test was evaluated and showed a high correlation coefficient by a standard curve (R value = 0.999). Based on the analytical instruction, the positive indication of the CNST contamination of brain and spinal cord was detected above 0.1% but large intestine, liver, lung, spleen, and heart was negative. Result suggests that the ELISA method is applicable to a real meat system and may provide a method to ensure confidence for consumer against bovine spongiform encephalopathy (BSE).

Release Behavior of Amlodipine Maleate an Excipient Rate and Variety

임동균,김용기,배정우,이동원,강길선 한국고분자학회 2011 한국고분자학회 학술대회 연구논문 초록집 Vol.2011 No.1

Effect of Packaging and Antioxidant Combinations on Physicochemical Properties of Irradiated Restructured Chicken Rolls

임동균,Dong U Ahn,남기창 한국축산식품학회 2015 한국축산식품학회지 Vol.35 No.2

Effects of double packaging (combinational use of aerobic and vacuum conditions) and antioxidants on physicochemical properties in irradiated restructured chicken rolls were determined. Chicken breast treated with antioxidants (none, sesamol+a-tocopherol) was used to process restructured chicken breast rolls. The sliced rolls were vacuum, aerobic, or double packaged (vacuum for 7 d then aerobic for 3 d) and electron beam irradiated at 2.5 kGy. Color, 2-thiobarbituric acid reactive substances (TBARS), oxidation reduction potentials (ORP), and volatile profiles of the samples were determined at 0 and 10 d. Irradiation made restructured chicken rolls redder (p<0.05), and the increased redness was more distinct in irradiated vacuum-packaged than irradiated aerobic or double packaged meats. TBARS values of antioxidant-treated double packaged rolls were lower than even nonirradiated vacuum-packaged meat, and those were distinct at 10 d (p<0.05). ORP and lipid oxidation values were lower in irradiated vacuum and double packaged samples than those in irradiated aerobic packaged ones at 0 d (p<0.05). Irradiation of restructured chicken rolls increased the amount of total volatiles. Considerable amounts of off-odor volatiles were reduced or not detected by double packaging and antioxidant treatment at 10 d. Therefore, the combined use of antioxidants and double packaging would be useful to reduce redness and control the oxidative quality changes of irradiated restructured chicken rolls.

Comparison of Physicochemical and Functional Traits of Hanwoo Steer Beef by the Quality Grade

임동균,차주수,조철훈,이경행,김종주,남기창 한국축산식품학회 2014 한국축산식품학회지 Vol.34 No.3

The physicochemical and functional traits for loin muscles of Hanwoo steers were compared by quality grade (QG). Atotal of 500 Hanwoo steers were slaughtered, their carcasses were categorized into four groups (QG 1++, 1+, 1, and 2), andthe longissimus dorsi muscles were analyzed. QG 1++ group had the highest fat and lowest moisture content (p<0.05). QG1++ showed higher L* and b* color values, higher cooking loss, and lower shear force values, compared with the othergroups (p<0.05). The flavor, tenderness, juiciness, and preference scores by sensory evaluation were highly ranked for pre-mium QG groups (1++ and 1+). Regarding the micro compounds, QG 1 and QG 2 had greater amounts of inosine mono-phosphate, and QG 2 had greater amounts of anserine, carnosine, and creatine, than QG 1++ (p<0.05). QG 1++ and 1+ hadhigher percentages of oleic acid (C18:1) than QG 2 (p<0.05). Within premium QG 1++ and 1+, the results of the nucle-otides, free amino acids, dipeptides, and fatty acids did not show any distinctive differences. Hanwoo beef as determined bythe current grading system was not significantly different in terms of functional components; the only significant differencewas in intramuscular fat content.

일반연제 발표 : T-Cell Clone을 이용한 결핵균 항원의 분석

임동균,서주영,박정규,황응수,국윤호,차창룡 대한결핵 및 호흡기학회 1990 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.71 No.0