Clinical Characteristics of Auricular Keloids Treated with Surgical Excision

박소영,오정훈,Guen-Ho Lee,Jung Mee Park,Sang-Gyun Jin 대한청각학회 2012 Journal of Audiology & Otology Vol.16 No.3

Background and Objectives: Differences in morphology of auricular keloids possibly contribute to distinct results of treatment. The aim of this study was to evaluate clinical characteristics of the auricular keloids according to the modified Chang-Park classification and to compare the results of treatment including recurrence rate between the subgroups. Subjects and Methods: Clinical data of 15 patients of auricular keloids were retrospectively reviewed. The keloids were classified according to modified Chang-Park classification. Clinical characteristics, the presence of recurrence, and the duration required for the recurrence were compared. Results: Eight out of 15 patients (53.3%) were single sessile type (type II), followed by 4 patients of pedunculated type, 1 patient of multiple sessile type, 1 patient of buried type, and 1 patient of mixed type, respectively. Recurrent keloids after previous surgeries were noted in 7 out of 15 patients and most of them (6 of 7, 85.7%) were sessile type. Three patients who underwent surgery at our department showed recurrence. Conclusions: The classification of auricular keloids according to morphologic patterns can assist surgeons in choosing the appropriate management.

습지생태공원의 갈대확장 조절 기술 개발

성기준 ( Ki June Sung ),이용민 ( Yong Min Yee ),정용현 ( Yong Hyun Chung ),박소영 ( So Young Park ) 한국환경보건기술학회(구 한국환경복원녹화기술학회) 2010 한국환경복원기술학회지 Vol.13 No.5

It is very difficult to control the expansion of reed at a wetland ecological park due to their aggressive reproduction capability. Therefore, proper topography and wetland hydrology should be provided before the construction of a wetland ecological park. Appropriate measures should be taken at the initial stages to prevent reed expansion. Field experiments were conducted at the newly constructed wetland ecological park for 15 months to develop methods to control the reproduction and expansion of Phragmites communis. A complete shading method had the best effect on the prevention of reed reoccurrence among other methods. Complete removal of the rhizomes controlled the reed growth to a greater extent than cutting the aboveground shoots. Water-level manipulation was also better than a half-shading method for the prevention of reed reproduction. These results indicated that soil properties and edge effects can influence the reed growth. Cutting only the aboveground shoots facilitates the growth of reed. These results suggest that reed control should be implemented repeatedly and an alteration in the wetland topography and hydrology may be more effective in the long term. Combination of treatments such as water-level management with shading should be considered to control the growth of reed. Adoptive management for created or restored ecosystem might be considered for accomplishment of its original purpose.

림프절의 염증성 가성 종양 - 세침흡인 세포학적 소견 1예 보고 -

박소영,공경엽,허주령,유은실,이인철,김온자,Park, So-Young,Gong, Gyung-Yub,Huh, Joo-Ryung,Yu, Eun-Sil,Lee, In-Chul,Kim, On-Ja 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.1

Reports on the cytologic or histopathologic findings of inflammatory pseudotumors are relatively infrequent and most of them have dealt with those involving the lung, liver, genitourinary tract, alimentary tract, spleen, mediastinum, retroperitoneum, etc. Moreover there have not been any cytologic studios of those involving lymph nodes. We present fine needle aspiration cytologic features of inflammatory pseudotumor occurring in a lymph node in a 64 year-old man. The aspirate consisted of proliferating spindle cells and admixed histiocytes, fibroblasts, lymphocytes, and plasma cells. Histiocytes were present either singly or in loosely cohesive small clusters. A few multinucleated giant cells were present as well. However, tuberculosis could be excluded by the absence of typical granuloma, caseation necrosis, or characteristic mixed spindle and inflammatory cell components. Other benign and malignant lymphadenopathies could also be differentiated based on cytologic findings.

유산균들의 콜레스테롤 저하성, 내산성, 내담즙성, 항생제 내성 비교

박소영,고영태,정후길,양진오,정현서,김영배,지근억,Park, So-Young,Ko, Young-Tae,Jeong, Hoo-Kil,Yang, Jin-Oh,Chung, Hyun-Seo,Kim, Young-Bae,Ji, Geun-Eog 한국미생물 · 생명공학회 1996 한국미생물·생명공학회지 Vol.24 No.3

For a probiotic yoghurt it is desirable to utilize lactic acid bacteria with a high survival rate and beneficial function to human beings. We have examined a variety of lactic acid bacteria to assess the acid and bile tolerance and antibiotic resistance. In addition, an in vitro culture experiment was performed to evaluate their ability to reduce cholesterol levels in the growth medium. Thirteen strains were selected from in vitro cholesterol assays and fed to Sprague-Dawley rats with a high-cholesterol diet. Among the 13 strains tested, 8 strains were shown to reduce serum cholesterol levels significantly after 24 days of administration in vivo. Rats were fed lyophilized yoghurt powder fermented with a combination of 3 selected strains: Bifidobacterium infantis AM-220, Lactobacillus AM-245, and Styeptococcus MA-1. The levels of total cholesterol and low density lipoprotein were significantly lower (p$\leq$0.05) in rats fed the yoghurt powder compared with control group. These studies suggest that yoghurt fermented with appropriately selected lactic acid bacteria may have a anticholesterolemic effect.

타액 연구의 최신 지견과 임상 응용

박소영,이은경,신종현,정태성,Soyoung Park,Eungyung Lee,Jonghyun Shin,Taesung Jeong 대한소아치과학회 2023 大韓小兒齒科學會誌 Vol.50 No.1

Function of salivary gland and saliva composition can be an indicator of individual's health status. Recently, saliva has been thought to have a high potential for usage in the biomedical field to diagnose, evaluate, and prevent systemic health due to the technological advances in analyzing and detecting small elements such as immunological and metabolic products, viruses, microorganisms, hormones in saliva. As a diagnostic specimen, saliva has some useful advantages compared to serum. Because of simple non-invasive method, saliva sampling is quite comfort for the patient, and it doesn't require specialists to collect samples. The possibility of infection during the collection process is also low. For this reason, proteins, genetic materials, and various biomarkers in saliva are actively being utilized on studying stress, microbiomics, genetics, and epigenetics. For the research on collecting big data related to systemic health, the needs on biobank has been focused. Regeneration of salivary gland based on tissue engineering has been also on advancement. However, there are still many issues to be solved, such as the standardization of sample collection, storage, and usage. This review focuses on the recent trends in the field of saliva research and highlight the future perspectives in biomedical and other applications.

Fructan 생성 S. salivarius의 인공치태 억제효과

박소영,박은혜,오종석,양규호,Park, So-Yung,Park, Eun-Hae,Oh, Jong-Suk,Yang, Kyu-Ho 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.1

구강 질환으로 중요한 치아우식증은 구강 세균 중 Streptococcus mutans가 주 원인균이며, 치면에 부착, 증식 및 산생성 과정을 거쳐 치아우식을 유발한다. Streptococcus salivarius는 사람의 구강에 정상적으로 존재하는 세균이다. 본 연구에서는 소아의 구강으로 부터 분리된 9주의 S. salivarius의 특성과 S. mutans 및 Streptococcus oralis에 대한 영향을 연구하여 다음과 같은 결과를 얻었다. 1. 비커 와이어 검사에서 S. mutans 배양시 형성된 인공치태 무게는 204.9 mg이었으나, S. mutans와 분리된 S. salivarius의 혼합 배양시 형성된 인공치태 무게는 1.9 mg에서 20.6 mg으로 S. mutans 단독 배양시와 큰 차이가 있었다(p<0.05). 배양 후 생균수 검사에서는 큰 차이가 없었다. 2. M17 액체배지에서 배양된 분리균주의 배양 상청액을 가한 비커 와이어 검사에서 형성된 인공치태 무게는 평균 117.1 mg인데 반해, 5% 자당이 함유된 M17 액체배지에서 배양된 분리균주 배양 상청액을 가한 비커 와이어 검사에서는 평균 47.7 mg이었다. 3. 분리된 S. salivarius의 배양 상청액을 thin layer chromatography를 실시한 결과, 분리균주가 형성한 중합체는 프럭탄 (fructan)이었다. 4. 비커 와이어 검사에서 프럭탄의 일종인 inulin과 levan 모두 S. mutans의 인공치태 형성을 억제하지 못하였다. 이상의 결과를 종합하면 프럭탄을 생성하는 S. salivarius는 S. mutans의 인공치태 형성을 억제하였다. S. mutans is the most important causative bacteria of dental caries among the oral bacteria. S. salivarius is a normal inhabitant in the human oral cavity. Nine strains of S. salivarius in this study were isolated from the oral cavities of children and identified, and their effect on S. mutans and S. oralis was studied. 1. The mean weight of produced artificial plaque on the wires in the beaker was 204.9 mg in the culture of S. mutans only, whereas being reduced to 1.9 mg through 20.6mg in the combined culture of S. mutans and each S. salivarius isolate (p<0.05). The viable cell didn't show the difference between them after culturing. 2. When S. mutans was cultured in the media containing culture supernatant of each S. salivarius isolate in M17 broth, the mean weight of produced artificial plaque was 117.1 mg on the wires, whereas being 47.7 mg in the media containing culture supernatant of each S. salivarius isolate in M17 broth containing 5% sucrose. 3. The polymer produced by S. salivarius isolates was on the thin layer chromatography. 4. Inulin and levan didn't inhibit the formation of artificial plaque by S. mutans in the beaker test. These results suggested that fructan-producing S. salivarius isolates inhibited the formation of artificial plaque by S. mutans.

F-144 Factors associated with outcome of patient with acute respiratory failure on pumpless extracorporeal interventional lung assist_pilot study

박소영,( Yousang Ko ),( Seung Hyeun Lee ),( Hong Mo Kang ),( Myung Jae Park ),( Yong Bum Park ) 대한결핵 및 호흡기학회 2016 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.121 No.-

Introduction: Pumpless interventional lung assist (iLA) have been advocated in patients suffering from severe acute respiratory failure . However, there is few evidence about factors with outcome of patient with acute respiratory failure using iLA. We evaluated effect and prognostic factor of the iLA in patients with acute respiratory failure Method: We evaluated retrospectively our experience with iLA between March 2013 and August 2016. iLA was implemented patients from multiple etiologies with severe hypercapnea(pH< 7.1 and PCO2 >70mmHg). Laboratory parameters,ventilator parameters, hemodynamic parameter and adverse events were recorded serially. Our primary outcome was ICU mortality. Results: Between March 2013 and August 2016, we enrolled 11 patients with severe respiratory failure, 2 patients had prone pone positioning using iLA and they all survived in ICU. iLA lead to an acute and moderate increase in arterial oxygenation (PaO2/FiO2 ratio 2hr after initiation of iLA (150 ±25 mmHg) compared with pre iLA(110 ± 20.2 mmHg). Hypercapnia was promptly reversed within 2hr (PaCO2, 35.9±12.4 mmHg) in comparison with before (75.9±23.4 mmHg , p < 0.05], which allowed a more protective ventilator strategy. In our study, ICU mortality is 36.4 %, SOFA score and lactate clearance were significantly related with ICU mortality. Conclusions: iLA might provide a sufficient rescue measure with easy handling properties in patients with severe hypercapnic respiratory failure. Also, prone position during iLA is safe and could be improved outcome.

P-28 Autophagy Primes Neutrophils for Neutrophil Extracellular Trap Formation during Sepsis

박소영,( Sanjeeb Shrestha ),( Young-Jin Youn ),( Jun-Kyu Kim ),( Shin-Yeong Kim ),( Hyun Jung Kim ),( So-Hee Park ),( Won-Gyun Ahn ),( Shin Kim ),( Myung Goo Lee ),( Ki-Suck Jung ),( Yong Bum Park ),( Eu 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.0

Rationale: Neutrophils are key effectors in the host’s immune response to sepsis. Excessive stimulation or dysregulated neutrophil functions are believed to be responsible for sepsis pathogenesis. However, the mechanisms regulating functional plasticity of neutrophils during sepsis have not been fully determined. Objectives: We investigated the role of autophagy in neutrophil functions during sepsis in patients with community-acquired pneumonia. Measurements and Main Results: Neutrophils isolated from patients who survived sepsis showed an increase in autophagy induction, and were primed for NET formation in response to subsequent PMA stimulation. In contrast, neutrophils isolated from patients who did not survive sepsis showed dysregulated autophagy and a decreased response to PMA stimulation. The induction of autophagy primed healthy neutrophils for NET formation and vice versa. In a mouse model of sepsis, the augmentation of autophagy improved survival via a NET-dependent mechanism. Conclusions: These results indicate that neutrophil autophagy primes neutrophils for increased NET formation, which is important for proper neutrophil effector functions during sepsis. Our study provides important insight into the role of autophagy in neutrophils during sepsis.

VoIP 긴급통신서비스 정책 및 표준화 동향

박소영,강신각,현욱,Park, S.Y.,Gang, S.G.,Hyun, W 한국전자통신연구원 2005 전자통신동향분석 Vol.20 No.5

인터넷전화 서비스의 원활한 제공을 위해 세계 여러 국가와 표준화 기구에서는 E911과 같은 긴급통신서비스 제공을 위한 정책 수립 및 기술표준화 활동을 수행하고 있다. 2005년 5월 미국 FCC가 인터넷전화 사업자의 E911 서비스 제공을 촉구하는 결정을 내린 바 있으며, 캐나다, 유럽, 아시아 등에서도 관련 정책을 마련하고 있다. IP 기반의 긴급통신서비스 제공과 관련된 표준화 활동은 IETF의 여러 WG과 NENA, TIA, ITUT등의 기구에서 진행되고 있으며, 특히 IETF ecrit WG에서는 인터넷 기술을 이용한 비상 호 라우팅을 위한 요구사항 개발 관련 작업이 이루어질 예정이다. 본 문서에서는 이와 같은 세계 여러 국가와 기구의 정책 및 표준화 활동을 비롯하여, 911 서비스를 제공하는 것으로 밝히고 있는 해외 인터넷전화사업자의 서비스 제공 동향에 대해 살펴본다.

산마늘 다신초 덩어리로부터 인경 형성과 비대에 미치는 methy jjasmonate의 영향

박소영,안진권,이위영,박혜진,Park, So-Young,Ahn, Jin-Kwon,Lee, Wi-Young,Park, Hae-Chin 한국식물생명공학회 2004 식물생명공학회지 Vol.31 No.1

산마늘의 다신초 덩어리로부터 인경형성을 위해 ABA와 MeJA가 첨가된 MS 배지에서 배양하였다. 저농도 (0.01mg/L)의 ABA처리구는 인경 형성보다 오히려 신초의 증식을 유도하였다. 인경은 MeJA처리구에서 배양 4∼6주 후 형성되기 시작하여 1.0mg/L MeJA 처리구에서 다신초 덩어리로부터 100% 인경형성이 이루어졌다. 조직학적 관찰 결과 생장조절제가 첨가되지 않은 배지의 인경과는 달리 MeJA처리구에서 비대된 인경의 외피세포는 크고 둥글며 단백질 등의 물질로 가득 차 있었다. 산마늘의 다신초 덩어리로부터 인경형성에 MeJA가 촉진적임을 알 수 있었다. The effect of abscisic acid (ABA) and methyl jasmonate (MeJA) on bulblet formation from the culture of Allium victorialis var. platyphyllum Makino was studied. Shoot clumps were cultured on MS medium containing ABA (0, 0.01∼2.0mg/L) and MeJA (0.01∼5.0mg/L). ABA at low concentrations (0.01mg/L) induced shoot proliferation without bulblet formation. However, bulblet formation started on the medium containing MeJA approximately in 4-6 weeks of culture. Furthermore, 1.0mg/L MeJA resulted in bulblet formation at high frequency (100%) as compare to the control (46.1%). Cortical cells of the bulblets enlarged on medium with MeJA had dense protein-like substance in expanded and round cells when examined under the microscope. The data described here show that formation and enlargement of bulblets from Allium victorialis can be improved by addition of appropriate concentration of MeJA.