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김병권,김정만,홍영습,정갑열,김준연,김성률,나서희 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3
We experienced a case of nephropathy in chronic lead poisoning The patient was 43-year-old male who has been working in secondary lead smelting plant for 14 years. On admission, blood pressure was 160/90 mmHg and the others were non-specific. In past history, he received chelating agent administration for lead poisoning irregularly and medicated for gout, and the blood lead concentration was 180.0 ㎍/dl on 2 months before admission. Smoking habit has been 1 pack per day for 15 years and drinking habit has been 1 bottle of Soju per day but less now. In liver function test, AST/ALT were 27/28 IU/l and γ-GT was 456 IU/l. In blood test, Hb : 11.5 g/dl, Hct : 34.0% and basophilic stipplings were found in peripheral blood smear. Chest PA was normal and abdominal ultrasonographic finding was non-specific except fatty liver. In the test of lead exposure indices, PbB : 83.0 ㎍/dl, PbU : 28.3 ㎍/l, and blood ZPP was 300.0 ㎍/dl. And in renal function test, BUN : 31.4 ㎎/dl, blood creatinine : 2.7 ㎎/dl, blood uric acid : 9.1 ㎎/dl, urinary albumin : 100.0 ㎎/g creatinine, urinary α-microglobulin : 120.5 ㎎/g creatininte, urinary β₂-microglobulin : 183.8 ㎍/g creatinine, and 24 hours urinary creatinine clearance was 31.9 ml/min. The ultrasonoguided renal biopsy showed the global sclerosis of glomerulus, moderate atrophy and loss of tubule, and interstitial fibrosis in light microscopy.
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나서희 ( Seo Hee Rha ),이수미 ( Su Mi Lee ),구태형 ( Tae Hyoung Koo ),신봉철 ( Bong Chul Shin ),허정훈 ( Jung Hun Huh ),엄수정 ( Soo Jung Um ),양두경 ( Doo Kyung Yang ),이수걸 ( Soo Keol Lee ),손춘희 ( Choon Hee Son ),노미숙 ( Mee 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.64 No.4
돈 혈청 투여에 의한 백서 간 중격상 섬유화에 있어서 비 적출 효과에 대한 연구
나서희(Seo Hee Rha),설미영(Mee Young Sol),이선경(Sun Kyung Lee) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.1
N/A Background/Aims: To elucidate splenic function in hepatic fibrosis, the authors evaluated the effects of splenectomy in experimental hepatic fibrosis. Methods: In splenectomized and non-splenectomized Sprague-Dawley rats, hepatic fibrosis was produced by intraperitoneal injection of normal swine serum. The liver tissue was examined hisiopathologically, immunohistochemically, and ultrastructurally and analyzed quantitatively. Results: The histopathological examination revealed mild septal fibrosis in three of ten at 6th week, mild to severe in five of ten at the 8th week, and severe fibrosis in six of ten at the 10th and 12th week in non-spelenectomized groups but no septal fibrosis through the observed time in splenectomized and control groups. The average number of fat-storing cells was significantly increased in both experimental groups, and increment of the number was more marked in nonsplenectomized ones. Electron microscopy revealed no morphologic differences in the ultrastructure of fat-storing cells between two groups, but there was a tendency of increment in the number of transitional cells in the nonsplenectomized group. Conclusions: It was considered that the hepatic fibrosis induced by administration of foreign sera would be due to activation of fat- storing cells, and that spleen would enhance the hepatic fibrosis by activation of FSC through certain splenic factors. (Korean J Gastroenterol 1996;28: 74 - 84)
홍종철,나서희,이현직,박헌수 대한이비인후과학회 2010 대한이비인후과학회지 두경부외과학 Vol.53 No.12
Small cell carcinoma is primarily a lung malignancy occurring rarely in extra pulmonary sites such as the larynx, nasal cavity, paranasal sinuses, and oral cavity. The diagnosis was based on histological investigation expanded with immunohistochemical tests of a fragment of a tissue. The immunohistochemical stain was positive for synaptophysin, CD56 and cytokeratin. So we diagnosed small cell carcinoma. The treatment of small cell carcinoma diagnosis differed from the treatment of other neuroendocrine carcinomas and squamous cell carcinomas of the larynx. We report a case of 72-year-old man with a rare case of small cell carcinoma in the supraglottic region and a brief review of literature. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:784-6