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      • Ruled Surface로 형성된 임펠러 블레이드의 5-축 가공에 관한 연구

        정대일,조현덕,윤문철,최두선,신보성,이응숙 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

        This paper describes the method and the process for impeller machining on 5-axis CNC machining center. Also, The CAD/CAM software for the impeller post processing is developed. The software can be interfaced with Solid-works software for confirmation of the impeller shapes. In this study, blades on impeller is described from Ruled-surfaces between two Ferguson curves. In this study, using 5-axis NC part program obtained from the developed software, a sample impeller was machined on 5-axis CNC machining center. The machined impeller was very agreeable to the designed impeller. Thus, theories proposed in this study can be very useful for the 5-axis machining of impeller blades with Ruled-surfaces.

      • 수중 재활 운동·치료의 대상에 따른 아쿠아 런닝 기초 원리적용에 관한 고찰

        정대철 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

        Advanced countries make processes each system and group which is related to underwater without any problem, on the other hand, a small number of people are directs applied by minority General hospitals, Welfare-states for handicapped people and Underwater -rehabilitation laboratories. These days, the studies about effect of underwater are advanced but are not enough a lot, Developmental combinations of underwater exercise and treatment are not only remarkable for rehabilitative elements as underwater therapy but come with reformation of the society and health preservation of general people. Aqua excercise Is applied Improving bases to Buoyancy, Resistance, Cooling effect, and Heart rate, We hope the aqua running's basic principle applications which are made conclusions by objects of treatment, underwater rehabilitation can take good evaluation recognizing the matters that demand special attentions, and also expect to share applications of various ways and everything.

      • 유지 투석중인 만성 신부전환자에서 허혈성 심질환의진단 지표로서의 심장트로닌-I의 유용성

        신병철,강대웅,정지용,류봉관,서영욱,김정인,김범윤,김현리,정종훈 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

        Background : Coronary disease is highly prevalent in patient with end stage renal disease (ESRD) and account for much of their observed morbidity and mortality. Troponin-I consistently maintains a high sensitivity and specificity and is most sensitive marker for ischemic heart disease (IHD). Method : We examed 49 hernodialyzed patients (22 male, 27 female) without evidence of acute coronary syndrome (ACS) for 6 months. Biochemical markers were measured in serial predialysis blood samples. For analysis, we used two cardio-specific assays for troponin-T (cTnT) as well as for troponin-I (cTnI) and compared the results with CK-MB (reference value ≤ 4.0 ng/mL) concentration. Results : Myocardial ischemia was observed in 47% (23/49) of patients. cTnT level above 0.1 ng/mL. and cTnI level above 0.5 ng/mL, were observed in 22% (11/49) and 20% (10/49) of patients respectively. cTnI revealed significantly higher positive rate in patients with myocardial ischemia than the patients without myocardial ischemia (43 % vs 30%) (p<0.05). cTnT and CK-MB revealed no difference in positive rate between the patients with and without myocardial ischemia (cTnT : 30% vs 15% and CK-MB : 30% vs 19%). The sensitivity and specificity of cTnI to myocardial ischemia were higher than those of cTnT and CK-MB (sensitivity 43% vs 30% and 30%. specificity 100% vs 85% and 81%). Conclusion: Both cTnT and cTnI are useful in ruling out myocardial injury in chronic renal failure patients. But. cTnI is a more sensitivity and excellent specificity of ischemic heart disease than cTnT and CK-MB in hemodialyzed patients. In patients with ischemic heart disease, the presences of DM and advanced age were higher than those in patients without ischemic heart disease (p<0.05). Among the baseline characteristics old age, elevated LDH and diabeties were significant more frequent in the patients with elevation of cardiac troponin-I (p>0.5 ng/mL) than those with cardiac troponin-I (p<0.5 ng/mL), p=0.038, p=0.049, and p=0.045, respectively. Our results suggest that these cTnI is the potential diagnostic marker for the prediction of IHD in ESRD patients.

      • 前立腺炎 外治法에 대한 文獻的 考察

        金大福,趙忠植,金哲中 대전대학교 한의학연구소 2002 한의학연구소 논문집 Vol.11 No.1

        According to the literature on the, the results were as follows. 1. The mechanism of External therapy for prostatitis is some medicicne to come into prostate have anti-inframation and the other medicine to come into nerve system control pain. 2. For the method are uesed hip bath, enema and stiching the pacth to the umbilicus etc. 3. For the medicine are used safflower(紅花), patrinia(敗醬草), chrysanthemum flower(菊花) and Cortex Phellodenri(黃柏). nature and flavor of the medicine is almost cold, bitter in taste and hot in taste. 4. For the classification of medicine are used drug to induce diuresis to elominate stranguria(利尿通淋藥) and drug to induce diuresis to dispersing swelling (利尿通淋藥). sometines they are used to Heat-clearing and detoxifying drug(淸熱解毒藥) and blood-quickining aget(활혈거어약).

      • 敗醬草가 癌細胞柱에 미치는 影響

        申大澈,權貞南,金瑩均,韓宗鉉,김재석,김재섭 동의대학교 한의학연구소 1997 동의한의연구 Vol.1 No.-

        The purpose of this study was to investigate effect of water extract of Patriniae Herba on the poliferation of human cancer cell-lines. The effects of Patriniae Herba on the poliferation of A43l, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay, The results were as follows; 1. Patriniae Herbs did not effect A43l, HeLa, MOLT-4, K562 cells. 2. The cytotoxicity of mitomycin C on MOLT-4 cells was increased by the combination of Patriniae Herba. 3. Patriniae Herba inhibited the proliferation of Balb/c 3T3 cells. 4. Patriniae Herba stimulated the proliferation of thymocytes. 5. Patriniae Herba stimulated the proliferation of splenocytes. 6. Patriniae Herba stimulated the proliferation of human lymphocytes.

      • KCI등재

        다양한 비스테로이드성 소염진통제의 쥐 피부 투과

        김민정,도희정,조원제,용철순,최한곤,이치호,김대덕 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.4

        Rat skin permeation of various nonsteroidal antiinflammatory drugs (NSAIDs) was investigated in vitro using Franz diffusion cell at 37℃. The effect of various skin permeation enhancers was also observed as a preliminary study of developing transdermal delivery systems of NSAIDs. Lipophilicity of NSAIDs was determined from the partition coefficient (log P) in 1-octanol/water and 1-octanol/IPB mutual-saturated solutions. The solubility was determined in water, isotonic phosphate buffer (IPB), and propylene glycol (PG) at 37℃. The rat skin permeation rate of acetaminophen, piroxicam, and aceclofenac was almost negligible, although they were saturated in PG. Addition of 1 % permeation enhancer increased the permeation rate of ketoprofen, ketorolac, and diclofenac. However, the skin permeation rate of ibuprofen did not increase with the addition of various enhancers. Among the permeation enhancers tested, oleic acid was the most effective for various NSAIDs. Based on the daily dose, lipophilicity, and the skin permeation rate achieved in this study, ketoprofen and ketorolac seem to be the most promising drug candidates for transdermal delivery systems, especially when formulated with unsaturated fatty acids, such as oleic acid.

      • 수입 외국산 모발세정용 화장품의 중금속 농도에 관한 연구

        문정아,문덕환,박명희,안진홍,김종은,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

        Objective : For the purpose of preparing the fundamental data and preventing the health impairment due yo heavy metals in hair cleaner. Methods and Material : The author determined the concentration of heavy metals(Fb, fn, Cr, Ni and Cu) in hair cleaner with flameless atomic absorption spectrophotometer. Results : The results were as follows : 1. The mean concentration of heavy metals in total hair cleaner were 0.046㎍/g for Pt, 0.O67㎍/g for Mn, 0.069㎍/g for Cr, 0.046㎍/g for Ni, and 0.022㎍/g for Cu, respectively. 2. There was not statistically significant difference to mean concentrations of each heavy metal in hair cleaner by producing nation. 3. The highest mean concentration of each heavy metal in hair cleaner by type of use were 0.140㎍/g for Mn in sensitive hair cleaner(p<0.05), 0.053㎍/g for Cu in others products(p<0.01). 4. The mean concentration of heavy metals in hair cleaner by type of hair cleaner were high at 0.O54㎍/g for Pb in shampoo products(p<0.O5), 0.120㎍/g for Cr and 0.06㎍/g for Cu in combination products(p<0.01). 5. The mean concentration of heavy metals in hair cleaner by acidity were high at 0.056㎍/g for Pb, 0.124㎍/g for Cr, and 0.032㎍/g for Cu in alkali products (p<0.05). 6. Correlation coefficient of heavy metal concentration in hair cleaner were 0.175 for Pb and Cr, 0.165 for Pb and Mn, 0.824 for Cr, and Mn, 0.189 for Cr, and Ni, 0.406 for Cr, and Cu, 0.197 for Mn and Ni, and 0.375 for Mn and Cu(p<0.05). 7. Exposure amount of heavy metals per when we used lOg of hair cleaner (onetime using amount) were 0.46㎍ for Pb, 0.67㎍ for Mn, 0.69㎍ for Cr, 0.46㎍ for Ni, and 0.22㎍ for Cu, respectively. Conclusion : As above results, there was very low level concentration of heavy metal in hair cleaner but we are using the hair cleaner everyday, therefore we can exposed to heavy metals as cronic exposure so the author suggest to prepare the program of preventing the health impairment due to heavy metals.

      • 이차성 기질화 폐렴이 동반된 피부근염 1예

        박철연,권정석,정진욱,이충기,현대성,최정윤 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

        Dermatomyositis is characterized by progressive, symmetric, Proximal muscle weakness and a nonsuppurative inflammatory myopathy of unknown etiology involving predominantly skeletal muscles. It is also characterized by typical skin lesions. Interstitial lung disease has a poor prognosis when it is associated with dermatomyositis. Organizing pneumonia is a disease in which granulation tissue fills the lumina of terminal and respiratory bronchioles and extends into the distal airspaces. The cryptogenic nature of the process is appreciated in that organizing pneumonia patterns of injury can be seen in secondary forms of the disease (secondary organizing pneumonia). Organizin pneumonia has been reported to occur in 5~10% in dermatomyositis-polymyositis patients Anti-histidyl tRNA synthetase antibody (anti-Jo-1) is a Predictive disease marker that is reported to occur in up to 70% of patients. We describe a 49-year-old male dermatomyosits patient who presented with organizing pneumonia and was found to have negative anti-Jo-1 antibody.

      • KCI등재

        다단토양층을 이용한 하수처리에 관한 연구

        손대희,정윤철,신정훈,정진영,안대희 한국물환경학회 2004 한국물환경학회지 Vol.20 No.3

        The sewages produced from small villages, rural community, drinking water reservation area and park which doesn't have sewage piping system can be caused a serious water pollution at the restricted areas. The objective of this research was to suggest an economical and effective sewage treatment method by investigating the removal of the organics, nitrogen, and phosphorus in the multi-soil-layering reactor. Soil, natural zeolite, and iron slag were used as a supporting media of multi-soil-layering in this research. The purpose of natural zeolite addition was to maintain the consistent ammonium exchange capacity by providing a sequential environment, and that of iron slag addition was to remove phosphorus by adsorption. Continuous experiment of lab-scale single-soil-layering (S-1), multi-soil-layering (S-2), and mixed-soil-layering (S-3) methods were studied to compare and optimize three different types of the reactors. The organic removal efficiencies showed more than 90% in all three reactors. While S-1 and S-3 reactors showed about T-N removal of 31%, 45%, respectively, the average T-N removal efficiency of the S-2 reactor represented an 87%. In conclusion, that results suggest that the multi-soil-layering reactor could be effectively utilized as a plant for treatment of small village sewage.

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