원문 : 가상화재상황의 초고층 건물 진입에 따른 소방공무원의 생리학적 반응

유동훈 ( Dong Hoon Yoo ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.3

유동훈. 가상화재상황의 초고층 건물 진입에 따른 소방공무원의 생리학적 반응. 운동과학, 제23권 제3호, 267-274, 2014. 본 연구는 가상화재상황의 초고층 건물 진입에 따른 소방공무원의 생리학적 반응을 알아보고자 시도하였다. 남자 소방공무원 8명(구조대원 6명, 화재 진압대원 2명, 31.9±4.4세)을 대상으로 초고층 건물 진입(HB: entry of high-rise building), 가상화재상황의 초고층 건물 진입(SF: simulated fire-fighting), 비교처치(CON: gym suit)의 3가지 처치를 실시하였다. 본 연구의 결과는 다음과 같다. 첫째, 가상화 재상황의 초고층 건물 진입에 따른 산소섭취량은 소방장비착용과 비교처치와 유의한 차이가 나타났다. 둘째, 심박수는 처치와 시기의 주 효과, 처치와 시기의 상호작용효과 모두 유의한 차이가 나타났으며, 3, 9, 12, 15분에서 HB와 SF는 CON보다 높게 나타났다. 셋째, 심부온도는 시기의 주 효과와 상호작용효과에서 유의한 차이가 나타났지만, 처치의 주 효과는 유의한 차이가 없었으며, 12, 15분에서 SF는 HB와 CON보다 높게 나타났다. 넷째, 피부온도는 처치와 시기의 주 효과, 처치와 시기의 상호작용효과 모두 유의한 차이가 나타났으며, 3, 6, 9, 12, 15분에서 SF는 HB와 CON보다 높게 나타났다. 다섯째, 운동자각도는 처치와 시기의 주 효과, 처치와 시기의 상호작용효과 모두 유의한 차이가 나타났으며, 6, 9, 12, 15분에서 SF는 CON보다 높게 나타났다. 본 연구는 초고층 건축물 가상화재상황에서 소방 활동 시 생리학적 변화에 대한 객관적인 자료를 제시하고자 하였다. 추후 대규모 소방공무원들을 대상으로 화재상황에서 안전한 임무 수행을 위한 체력의 기준이 제시되어야 한다고 사료되며, 다양한 소방 활동 임무와 생리학적 변인에 관련된 연구가 이루어져야 할 것이다. Yoo, Dong-Hoon. Physiological Response in Accordance with High-Rise Building of Simulated Fire-Fighting in Fire-Fighters. Exercise Science, 23(3): 267-274. 2014. The purpose of this study was to investigate fire-fighters` physiological response in case of simulated fire-fighting of high-rise building. Eight male fire fighters (6 rescue workers, 2 fire suppression workers; 31.9 4.4 yrs) participated in this study. Each participants performed under the three conditions (HB: entry of high-rise building, SF: simulated fire-fighting, CON: gym suit). The results were as follows: First, oxygen consumption was significantly different between SF and CON. Secondly, heart rates showed difference in both main effect and interaction effect of treatment and time. HB and SF were higher than CON at 3, 9, 12, and 15 min. Thirdly, tympanic temperature showed significant difference in main effect of time and interaction effect of treatment and time. SF was higher than HB and CON at 12, 15 min. Fourth, skin temperature showed difference in both main effect and interaction effect of treatment and time. SF was higher than HB and CON at 3, 6, 9, 12, and 15 min. Lastly, rating of perceived exertion showed significant difference in both main effect and interaction effect of treatment and time. S F was higher than CON at 6 , 9, 1 2, and 1 5 min. Physical standard of fire-fighters based on this study will be suggested in order to provide the guideline for their job safety. Further research on physiological variables during various fire-fighting tasks should also be carried out for more systematic physical guideline to enhancing fire-fighters` job safety.

파활동경사를 고려한 소파블록 중량산정

유동훈(Yoo Dong Hoon),윤종주(Yoon Jong Joo),정평교(Jung Pyung Kyo),장문엽(Jang Moon Yup) 대한토목학회 2009 대한토목학회 학술대회 Vol.2009 No.10

비선형효과와 파형경사를 고려한 소파블럭 중량산정

유동훈(Yoo Dong Hoon),윤종주(Yoon Jong Joo),장문엽(Jang Moon Yup) 대한토목학회 2010 대한토목학회 학술대회 Vol.2010 No.10

牛蒡子의 抗알러지 效果에 對한 硏究

兪漢鐵,金聖勳,金東熙 대한본초학회 2001 大韓本草學會誌 Vol.16 No.1

To evaluate the effectiveness of Arctii Fructus(AF) in the treatment of allergy, studies were done experimentally. The results were obtained as follows : 1. Cytotoxicity of AF extract on the mouse lung fibroblast cells was not shown below the level of 100 ㎍/㎖ concentration. 2. In the quantification of IL-1β gene development, the amount was decreased compared to control group, gut which was insignificant. 3. Gene development of IL-4 was suppressed over 70% in the concentration of 100㎍/㎖ and also the of production of IL-4 was decreased significantly in the concentration of 100㎍/㎖ compared to the control group. 4. Gene development of Il-5 was decreased to 60% in the concentration of 100 ㎍/㎖ compared to the control group. 5. Gene development of IL-4 and IL-10 were decreased compared to the control group, but which was not significant. 6. Gene development of TNF-α was suppressed over 60% in the concentration of 10 ㎍/㎖ compared to the control group. 7. The effect of suppression of IgE production was significantly decreased in the concentration of 100㎍/㎖. 8. The effect of suppression of Histamine release was decreased significantly in the concentration of 100 ㎍/㎖. According to the above results, AF has antiallergic effects and suppression of the immune response. Thus it is suggested that aqua extract of AF could be applied to the aqua-acupuncture for suppressing humoral immune response, and further research is recommended.

연부조직 육종에서 Cyclin D_(1) 유전자의 증폭에 대한 연구

유재훈,정동준,이정은,김창진 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

The molecular mechanisms of the soft tissue sarcoma is not elucidated. In general, deregulations of the several genes such as oncogenes, antioncogenes, genes regulating apoptosis and cell cycle are known to take part in the carcinogenesis of most carcinomas. Moreover, deregulation of the cell cycle is one of the major carcinogenic mechanisms. The cyclin D_(1) is the most important gene regulating the transition, G_(1). to S, which is the most importan check point in cell cycle. The cyclin D_(1) gene amplification was reported in various carcinomas, but not in sarcomas. In this study, we studied the cyclin D_(1) expression in 10 liposarcomas, 5 rhabdomyosarcomas and 5 malignant fibrous histiocytomas by imunohistochedmistry, and real-time polymerase chain reaction. The results were as follows; 1. Immunohistochemically, liposarcoma and malignant fibrous histiocytomas expressed moderate degree of cyclin D_(1), however expression was noted in few rhabdo- myosarcomas. 2. The cycline D_(1) gene amplification was not different between normal and sarcomas(p>0.05). 3. There was no positive correlation between cyclin D_(1) expression by immunohistochemistry and cylin D(1)gene amplification. Above results suggest that cyclin D_(1) gene amplifacation does not contribute to the oncogenesis of the sarcomas, and cyclin D_(1) expression by immunohistochemistry does not correlate with the gene amplification. As the sample cases are limited in this study, forther studies with more samples are needed.

5급 복합레진충전된 치아에 있어서의 계면조건과 유지구의 영향에 대한 2차원유한요소법적 연구

김동호,유현미,조병훈 大韓齒科保存學會 1998 Restorative Dentistry & Endodontics Vol.23 No.2

유치에 적용된 All-in-One 상아질 접착 시스템의 전단강도에 관한 비교연구

김동철,김종수,유승훈 大韓小兒齒科學會 2007 大韓小兒齒科學會誌 Vol.34 No.4

유치 60개를 준비하였으며,사용된 접착 시스템은 AQ Bond Plus™,G Bond™ Single Bond™였다. 유치의 법랑질과 상아질을 노출시킨 후 제조사의 지시에 따라 접착 레진을 적용한 후,내경 1.7 mm의 폴리에틸렌 튜브를 이용하여 Z-250™ 복합레진을 수복하였다. 100% 습윤 상태에서 24시간동안 보관 후 5℃와 55℃ 조건하에서 500회 열순환을 시행 후 만능시험기로 전단결합강도를 측정하였다. Resin tag 관찰을 위하여 상아질 접착면에 대해 수직으로 절단하고 인산과 질산으로 처리하여 치질을 용해시킨 후 주사 전자 현미경으로 관찰한 결과 다음과 같은 결론을 얻었다. 1. 유치 법랑질에서 측정된 전단 결합 강도는 AQ Bond Plus™에서 1.04 ± 0.13 MPa,G Bond™에서 1.23 ± 0.35 MPa,Single Bond™에서 1.28 ± 0.50 MPa이었으며,세 군 간의 유의차는 없었다. 2. 유치 상아질에서의 전단 결합 강도는 AQ Bond Plus™는 1.15 ± 0.37 MPa, G Bond™는 1.69 ± 0.74 MPa 그리고 Single Bond™는 0.56 ± 0.11 MPa로 나타났으며,AQ Bond Plus™와 G Bond™ 간에는 통계학적 유의차가 없었으나(p)0.05),AQ Bond Plus™와 Single Blon™, G Bond™과 Single Bond™ 간에는 통계학적 유의차를 보였다. 3. 주사 전자 현미경 소견에서 AQ Bond Plus™와 G Bond™는 resin tag 형성이 매우 미약하고 짧은 양상을 보인 반면,Single Bond™에서는 길게 형성된 resin tag가 관찰되었으며 resin tag의 표면에 불규칙하게 형성된 측부 가지들이 관찰되었다. This study was performed to compare the shear bond strength of primary enamel & dentin treated by AQ Bond Plus™ and G Bond™, recently developed 6th generation dentin bonding system, to that of Single Bond™ being widely used. Also by observing the resin tag under scanning electron microscope, Resin tags of each material were also observed under scanning electron microscope and compared to one another. The possibility of clinical application of AlHn-One system which has an advantage to reduce chair-time for children with difficult behavior pattern was evaluated. The results obtained are as follows: 1. No statistically significant difference between groups was found in shear bond strength of primary enamel. 2. In primary dentin, the shear bond strength of AQ Bond Plus™ was 1.15±0.37 MPa, G Bond™ was 1.69±0.74 MPa and Single Bond™ was 0.56 ± 0.11 MPa. There were no statistical difference between AQ Bond Plus™ and G Bond™ and between G Bond™ and Single Bond™, whereas statistically significant difference was found between AQ Bond Plus™ and Single Bond™. 3. Under scanning electron microscope, resin tags observed in AQ Bond Plus™ and G Bond™ were very weak and tangled while strong and thick tags were shown with many lateral branches in Single Bond™. The result of the present study coupled with the advantages of less working time over the previous generation suggests that All-in-One system might be effectively used in adhesive dental procedures for primary teeth.

고출력 CW Nd:YAG 레이저를 이용한 CSP 1N 박판재 절단시 공정변수의 절단표면특성에 미치는 영향

안동규,김민수,이상훈,유영태,박형준 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-

The objective of this research work is to investigate the influence of process parameters, such as power of laser, travel speed of laser and material thickness, on roughness and striation of the cut surface for the case of cutting of CSP IN sheet using high power Nd:YAG laser with continuous wave (CW). In order to find the practical cutting region and the relationship between process parameters on the roughness and the striation, several laser cutting experiments are carried out. From the results of experiments, the allowable cutting region and an optimal cutting speed for each cutting condition have been obtained to improve the quality of the cut surface. In addition, it has been shown that the surface roughness is related to the number of striation and depth of valley of the cut surface.

항결핵 치료과정에서 호전되었다가 악화된 뇌 결핵종 1예 보고

이대훈,유진홍,강미자,김홍기,김선화,고동훈,천지성,유원종 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.3

In spite of nationmide tuberculosis control program, tuberculosis is still prevalent in Korea. Accordingly, tuberculous meningitis also poses one of the main trouble some problems. Recently, We experienced a perplexing case of tuberculous menin-gitis and tubercdoma in a 24-year old female patient. She was admitted to our hospital owing to meningeal irritation sign, aphasia, VI nerve palsy, and ,fever. CSF analysis showed a finding consistent with that of presumptive tuberculous meningitis.. Initial MRI of the brain revealed a large mass(tuhercu1oma) on left parieto-temporal area. Antitubeculous regimen(1soniazid (INH), rifampin(RMP), ethambutol(EMB), pyrazinamide(PZA)} of meningeal dose was given immediately, and her symptoms and signs were dramatically disappeared with a few days after treatment. She was discharged with improved condition and under maintenance treatment of tuberculosis. Follow-up one year after treatment. revealed that the previous lesion was nearly diminished. She showed no symptom at all until she recognized a total blindness of sudden onset on her left eye a t the 18th month of treatment. Brain MRI checked at that time showed multiple masses of tuberculoma scattered over the brain base and one of them invaded left optic nerve. In our opinion, the cause of relapse in this patient might he explained by the selection and ultimate replication of a minor population of resistant strain. Although such relapse is an extremely rare event, we think that we should always pay attention to this possible resistance problem every time we meet patients with tuberculous meningitis.

Aspergillus nidulans 에서 nsdD 유전자의 cDNA 클로닝

한갑훈,한유정,한동민 원광대학교 생명공학연구소 1995 생명공학연구소보 Vol.3 No.1

In Aspergillus nidulans, Never in Sexual Development(nsdD) gene is required for the early stage of sexual development. A region of the A. nidulans genomic DNA carrying the nsdD gene which complements NsdD19 mutation was isolated by transformation of NsdD19 mutant with a cosmid library. The size of the subcloned gene was about 4kb-long and the plasmid containing the 4kb DNA fragment, pNSD19-SB4, was cloned. 2.5kb and 2. 1kb cDNAs of nsdD gene were obtained from the sexual-development specific cDNA library by plaque hybridization and cloned into pBluescriptⅡ KS+.