지연성 운동장애와 양성, 음성 정신분열병 환자에서의 인지기능 장애

유범희,김지혜,배주미,이강욱,우종민,김승태 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

저자들은 정신분열병 환자에서 양성, 음성 증후군에 따라 각각 특징적으로 어떤 인지기능의 장애를 보이는지 알아보며, 또 지연성 운동장애의 존재 여부가 인지기능에 어떤 영향을 미치는지 조사해보고자 지연성 운동장애 환자 31명과 대조군 32명에게 PANSS 검사를 시행하였고, 인지기능 검사로는 KWIS 검사와 Grooved Pegboard test, Trail making test A/B, Wisconsin card sorting test, Wecshler memory scale을 시행하였다. 그 결과 다음과 같은 성적을 얻었다. 1) KWIS 지능검사상 이해 소검사에서 양성 증후군 환자들이 음성 증후군에 비해 우수한 수행도를 보였으며 빠진 곳 찾기 소검사에서는 지연성 운동장애가 없는 집단이 있는 집단에 비해 우수한 수행도를 보였다. 2) Trail making test A형에서 양성 정신분열병 환자 집단이 음성 정신분열병 환자 집단에 비해 전반적으로 빠르고 효율적인 수행을 보였다. 3) 그밖의 다른 인지기능 검사상에서는 양성, 음성 정신분열병과 지연성 운동장애 유무에 따른 검사 결과의 차이는 보이지 않았다. 결론적으로 음성 증후군 환자들의 경우 양성 증후군에 환자들에 비해 실행 기능과 같은 전두엽 기능의 장애와 기억 능력의 저하가 좀더 분명하게 나타나 음성 증상과 인지기능 장애 사이에 통계적으로 의미있는 상관관계가 있는 것으로 나타났다. 반면 지연성 운동장애의 경우는 음성 증후군과 함께 나타날 때만 현실 검증력, 주의력의 저하가 두드러져서 지연성 운동장애 자체만으로 인지기능의 장애가 유발된다고 보기는 어려웠다. Objective : The goal of this study was to examine cognitive dysfunctions in positive and negative schizophrenic patients and investigate the effect of tardive dyskinesia on cognitive dysfunctions in them. Methods : Thirty two schizophrenic patients with tardive dyskinesia and thirty two schizophrenic patients without tardive dyskinesia as a control group were selected from psychiatric inpatients at a lunatic asylum and the cognitive dysfunctions of these patients were assessed with some neuropsychological tests including KWIS test, Grooved Pegboard test, Trail making test A and B, Wisconsin card sorting test, and Wechsler memory scale test. From these patients, we classified eighteen schizophrenic patients as a positive syndrome group and twenty five patients as a negative syndrome group with positive and negative syndrome scale and compared the results of neuropsychological tests between these two groups. Results : Patients without tardive dyskinesia showed better performances than those with tardive dyskinesia on picture completion subtest of KWIS. Positive schizophrenic patients showed better performances than negative schizophrenic patients on comprehension subtest of KWIS and trail making test A. Conclusion : Negative schizophrenic patients showed frontal lobe dysfunction and more memory impairment than positive schizophrenic patients. In conclusion, negative syndrome of schizophrenia is significantly associated with cognitive dysfunctions although tardive dyskinesia is not.

습식 생산방식에 의한 재생 잔골재를 사용한 콘크리트의 중성화 저항성 및 건조수축에 관한 실험적 연구

유명열,김병윤,이세현,심종우 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study was to provide durability data of concrete using recycled fined aggregate which was produced through a wet production process for making it sure whether it can be put to practical use for concrete. In the experiment, recycled fine aggregate was substitute for natural fine aggregate the rate of 0, 25, 50, 75 and 100% each. The results of the study were as follows; 1 The depth of neutralization was become deeper according to the increase of substitutive ratio of recycled fine aggregate. 2 The performance of length alternation was fallen gradually according to the increase of substitutive ratio of recycled fine aggregate. Hut, it showed the similar durability with concrete using natural fine aggregate fewer than 50% substitution ratio. Bused on the above results, it is concluded that the recycled fine aggregate through the wet production process can be used IS fine aggregate on condition that the substitution ration is under 50%.

광기능성 폴리머의 소산장 결합을 이용한 측면연마 광섬유형 자외선 센서

김상우,서규원,윤종국,장수원,유윤식,이승하,강신원 한국센서학회 2002 센서학회지 Vol.11 No.6

측면연마된 광섬유와 광기능성 색소가 분산된 평면도파로 결합기를 이용한 새로운 형태의 자외선센서를 제작하여 그 특성을 측정하였다. 자외선 조사에 의해 유효굴절률이 변화하는 광변색성 색소가 분산된 폴리머를 평면 도파로 재료로 사용하였다. 박막 광도파로는 광변색성 색소인 스파이록사진을 사용하였다. 자외선 조사시간을 20초, 30초, 40초로 증가시켰을 경우 센서의 파장응답은 1.44nm/mW, 1.64nm/mW, 1.78nm/mW였고 1550nm 파장에서 센서의 90% 복귀시간은 100초로 나타났다. In this paper, we investigated a novel UV sensor using evanescent field coupling between the side polished fiber and photo-functional polymer waveguide. It was found that resonant wavelength shifts occur due to variation in the refractive index of polymer planar waveguide for its photo-functional properties on exposed UV. Spiroxazine (photochromic dye) was used as the planar waveguide. The resonant wavelength response were exhibited at 1.44 nm/mW, 1.64 nm/mW, and 1.78 nm/mW when UV irradiations were exposed for 20 seconds, 30 seconds, and 40 seconds, respectively. The recovery time of sensor was independent of UV exposure power and 90% recovery time was 100 seconds.

유해화학물질의 계통분석

박성우,박유신,이진훈,유재훈,김유나,오세진,이진숙,김남이,박종신,남금문,노동석 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

강진만에서 미생물의 년 변화

박종천,오재영,정용욱,주현수,이원교,유춘만,이우범 國立 麗水大學校 환경문제硏究所 2001 環境硏究論文集 Vol.4 No.-

The biological surveys were performed at seven sites in the Gangjin bay from February, 1998 to November, 2001. In order to analysis of environmental variation, numbers of heterotrophic bacteria, general fungus and fecal coliforms were enumerated in each sample. The result showed that variation range of heterotrophic bacteria, general fungus, and fecal coliforms were 2.9 x 10^(3)~9.6 x 10^(3) CFU/ml, 17.2~80.1 CFU/ml, and 6.3~682.5 CFU/100ml for four tears(1988~2001), respectively. Density of heterotrophic bacteria and general fungus were gradually decreased for four tours, while fecal coliforms were suddenly increased. Specially, numbers of fecal colifoms were increased the more 100 times in 2001 than that 1998. We think that it was probably caused a little rainfall in February, 2001. There result suggests that ecosystem of Gangjin bay were mainly regulated by 2~3 factors, which were inflow of fresh water, salinity and variation of water temperature.

維新벼에 나타난 生育後期의 萎週

朴鍾聲,金文圭,禹基大,劉勝憲 충남대학교 농업과학연구소 1977 農業技術硏究報告 Vol.4 No.1

1. Chemical properties of soils and inorganic compositions of rice plants were analysed to explain the acute wilting occurred in the late stage of rice variety, Yusin. The results obtained were summarized as follows. 1) The amount of K and S_iO_2 of soils where severe rice wilting occurred was lower than that of soils where rice wilting didn't occurred. 2) The amount of N and FeO of wilted rice plants was higher than that of normal rice plants while the amount of K_2O and SiO_2 and the ratio of K_2O/N of former were lower than that of letter. 2. Severe wilting was occurred only in the rice variety, Yusin, when three varieties… Yusin, Milyang #15, Milyang #23……were interplanted. The amount of organic and inorganic compositions of three varieties and chemical properties of rhizosphere soils were analysed. 1) The rice variety, Yusin, was the lowest and that of the rice variety, Milyang #15, was the highest in the level of total carbohydrate and hemicellulose. 2) Comparatively higher levels of K were observed in rhizosphere soil where Yusin was planted, while the level of the K in the plant of Yusin was the lowest.

악성림프종 환자에서 복합화학요법으로 유발된 백혈구 감소증에 대한 인형 재조합 과립구 집락형성-촉진인자(rhG-CSF: Neutrogin)의 효과

박성규,전진우,기신영,유병우,김홍수,백승호,원종호,홍대식,박희숙 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Clinical effects of rhG-CSF were investigated in 17 patients receiving chemotherapy for non-Hodgkin's lymphoma. Patients were given G-CSF 2㎍/㎏/day after 2nd cycle chemotherapy for least 14 consecutive days, and clinical and laboratory results were compared to results of the first cycle. Treatment with G-CSF resulted in increase of mean WBC count(952.9±152.2㎜³vs 1882.4±350.4/㎜³) and neutrophil count(212.9±53.0/㎜³vs 841.5±238.0/㎜³), reduced the duration of leukocytopenic days(12.4±1.3 days vs 5.5±1.0 days, WBC count less than 4000/㎜³) and neutropenic days(4.5±0.9 days vs 2.3±0.7 days, neutrophil count less than 500/㎜³), and reduced the duration of neutropenic fever(5.8±1.1 days vs 0.9±0.5 days). The side effects of G-CSF were not so significant. These results demonstrated that G-CSF is safe and useful for the treatment of neutropenia induced by anticancer chemotherapy of non-Hodgkin's lymphoma and reducing the incidence of febrile periods and duration of antibiotic administration.

Eisenmenger씨 증후군 산모의 긴박 제왕절개술시 전신마취 경험

김준,고우석,정종달,유병식,임경준,소금영,안태훈,한승룡 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Eisenmenger's syndrome describes a situation in which the left-to-right intracardiac shunt is reversed as a result of increased pulmonary vascular resistance. The patients with Eisenmenger's syndrome are poorly tolerated and markedly increased maternal mortality to 30 - 50% during pregnancy, Physiological change of pregnancy decreases systemic vascular resistance that further aggravates the bi-directional or left shunt associated with Eisemnenger's syndrome. We report a case of 37 weeks a pregnant woman with an urgent cesarean section under general anesthesia for preterm labor. She was a pregnant patient with Eisenmenger's syndrome and did not receive antenatal care during pregnancy. Anesthesia was induced with ketamine-midazolam-fentanyl and maintained with ketamine-midazolam. The patient was ventilated with 100% O₂. Blood pressure was maintained with intravenous phenylephrine, crystalloid solution, and blood. Phenylephhne was used to maintain systemic vascular resistance (SVR). Even though the patient was carried rapid and adequate medical management, the patient was transferred to the ICU in an intubated state and died 2 days after surgery. We conclude that the parturients with Eisenmenger's syndrome require more regular, careful antenatal care, monitoring, and adequate management.

실리콘樹脂를 利用한 文化財保護被膜에 對한 硏究

黃正儀,朴斗元,吳相午,鄭倧在,朴裕哲,郭永佑 慶北大學校 1977 論文集 Vol.23 No.-

金屬실리콘과 鹽化메틸을 鹽化第一구리를 觸媒로 하여 메틸실란을 合成하고 메틸실란을 加水分解하여 실록산의 被膜을 만드는 方法을 調査하였다. 이들 被膜이 文化財 保護被膜이 될 수 있는가를 檢討하기 爲해서 材料를 文化財의 材質인 몇 가지 物質에 適用하여 膜의 性能을 調査하였다. 特히 撥水效果, 汲水量 耐久性等을 調査하였으며 外觀上 아무런 變化가 없는 좋은 被膜이 될수 있다는 結果를 얻었다. The organohalogensilicone was synthesized metal silicone and methylchloride applying the direct synthetic method using copperous chloride as catalyzer. The synthesized organosilane was hydrolyzed to siloxane by various method and coated on various materials which are composed of the cultural assets. The coating film was examined to decide whether it is profitable one to protect the assets from efflorescence or air pollution. Referring to the water repellency, permiability of water and the weather test of the film it was qualified that this film was good enough to apply to the cultural assets as protecting film.

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.