류마티스관절염과 만성 호산구성 폐렴에 동반된 호산구성 흉막삼출

지용관 ( Yong Gwan Jee ),라상호 ( Sang Ho Ra ),박유미 ( Yu Mi Park ),차재황 ( Jae Whang Cha ),강용석 ( Yong Seok Kang ),박정하 ( Jeong Ha Park ),강태영 ( Tae Young Kang ) 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.5

We describe a 48-year-old man with family history of rheumatoid arthritis (RA) affected by chronic eosinophilic pneumonia (CEP) with severe peripheral eosinophilia. CEP might develop as a complication of longstanding active RA. The patient with 5 months history of seropositive RA and chronic respiratory symptoms, alveolar and blood eosinophilia, peripheral pulmonary infiltrates and pleural effusion on chest imaging. The lung may be involved as an extraarticular manifestation of RA. However, CEP is not recognized as a typical lung manifestation of RA, and the two diseases rarely coexist. The effusion was an eosinophil predominant exudates and was characterized by low pH, and glucose level and high lactic dehydrogenase. The patient responded rapidly to combination of steroids and disease modifying anti-rheumatic drugs.

혈전성 혈소판감소성 자반증으로 발현된 전신홍반루푸스 1예

오명근,유미라,변유미,윤찬영,권세훈,박치영,김상현 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening syndrome characterized by the classic pentad of clinical features that includes microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction. Early diagnosis and utilization of plasmapheresis can improve the survival rates of patients with TTP. TTP rarely may be seen in association with autoimmune disease such as systemic lupus erythematous (SLE). We report here a 42-year-old female who was presented with severe digital gangrenes, microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction. Her condition responded to combined therapy with high dose steroid, immunosuppressants, and plasmapheresis therapy.

정신분열병 환자에서 얼굴 영상의 작동기억 장애 : 기능자기공명영상연구

이창욱,김태석,주라형,박주미,박여진,김종진,전신수,배치운,김정진,이수정,이철,백인호 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Objectives : Impaired processing of facial information is one of the broad ranges of cognitive deficits seen in patients with Schi-zophrenia. We aimed to elucidate the differences in brain activities involved in the process of facial working memory between schizophrenic patients and healthy comparison subjects. Methods : Twelve patients with schizophrenia were recruited along with twelve demographically matched healthy volunteers as a comparison group. Functional magnetic resonance imaging (fMRI) was used to assess cortical activities during the Perfor-mance of a 2-back working memory paradigm using images of neutral faces as mnemonic content. Rcsults : The patient group performed the tasks with reduced accuracy. Group analysis revealed that the left fusiform gyrus, the right superior frontal gyrus, the bilateral middle frontal gyri/insula, the left middle temporal gyrus, the precuneus, the quadrangular lobules and the vermis of cerebellum showed decreased cortical activities in the patient group. On the other hand, an increased level of activation in the lateral prefrontal cortex and the pahetal lobule was observed from the patient group, all in the right hemisphere. Conulusion : A decreased level of activity in the left fusiform gyrus among the patient group implicates inefficient processing of facial information. An increased level of activation in prefrontal and parietal neural networks from the patient group confirms earlier findings on the impaired working memory of patients with schizophrenia.

Next generation sequencing analysis of exosomal microRNAs: Fusobacterium nucleatum regulates expression profiling of exosomal microRNAs in human colorectal cancer cells

Mi Ra Yu,Hye Jung Kim,Ji Wan Kang,Yun Hak Kim,Hae Ryoun Park 대한구강생물학회 2020 International Journal of Oral Biology Vol.45 No.3

Colon cancer is one of the most common malignant tumors, but there are still a few validated biomarkers of colon cancer. Exosome-mediated microRNAs (miRNAs) have been recognized as potential biomarkers in cancers, and miRNAs can regulate a variety of genes. Recently, Fusobacterium nucleatum was discovered in the tissues of human colon cancer patients. Its role in colon cancer was highlighted. F. nucleatum may contribute to the progression of colon cancer through the mechanism of exosome-mediated miRNAs transfer. However, the exosomal miRNAs regulation mechanism by F. nucleatum in colon cancer is not well known. Thus, we performed next-generation sequencing to investigate the overall pattern of exosomal miRNAs expression in the colon cancer cell culture supernatant. We have confirmed the alterations of various exosomal miRNAs. In addition, to investigate the function of exosomal miRNAs, a Kyoto Encyclopedia of Genes and Genomes analysis was performed on the target genes of changed miRNAs. Potential target genes were associated with a variety of signaling pathways, and one of these pathways was related to colorectal cancer. These findings suggested that F. nucleatum can alter exosomal miRNAs released from colorectal cancer cells. Furthermore, exosomal miRNAs altered by F. nucleatum could be potential biomarkers for the diagnosis and therapy of colon cancer.

A Comparative Analysis of Habitability Aspects of Temporary Shelters for Disaster Victims between South Korea and the U.S.

Yu Ra Choi,Mi Kyung Kim,Seon Mi Choi 위기관리 이론과 실천 2018 Crisisonomy Vol.14 No.10

본 연구의 목적은 한국과 미국의 미디어 자료를 통해 주요 재난 발생 이후 공급된 이재민 임시주거시설 현황을 이재민의 거주성 관점에서 비교분석하여 국내 시사점을 파악하는 것으로 주요 연구결과는 다음과 같다. 첫째, 한국의 지진겸용 이재민 임시주거시설은 내진설계가 취약한 시설이 지정되어 2차 여진 후 시설 일부 붕괴, 대피의 장기화로 인한 문제점 등 이재민의 안전성, 편리성, 쾌적성측면에서 문제점이 나타나 시설 지정과 관련된 기준과 거주성 측면이 고려된 지침개발이 필요하다. 둘째, 대홍수로 인한 재해가 많은 미국의 이재민들 또한 임시주거시설에서 사생활 침해와 안전성에 대한 문제점을 겪었으나, 트레일러나 조립식 주택 등 이미 제작된 주거유형 공급으로 보다 안전하고 쾌적한 환경을 제공한 점이 주요 차이점으로 나타났다. 셋째, 시설의 비위생성과 이로 인한 이재민 건강 문제는 한국과 미국의 임시주거시설에서 공통적인 주요 문제로 나타났는데, 이러한 점을 향후 계획적 측면에서 고려해야 할 것이다. The purpose of this study was to examine habitability aspects of temporary shelters provided for disaster victims between South Korea and the U.S. by analyzing the mass media content. First, Korea s temporary shelters(earthquake) are designated as facilities with weak seismic design, it had led to problems with safety, convenience, and comfort, so should be developed guidelines considering criteria and habitability of facility designation. Second, since catastrophic disasters often occurred in the U.S., evacuees had to stay in mega-shelters and went through the trouble due to the invasion of privacy and the lack of safety, but additional options, such as trailers and manufactured homes, were available for providing disaster victims with a safe, comfortable environment. Third, the unsanitary and unhealthy condition was considered as a common major problem of temporary shelters in both countries, which needs to be carefully addressed in the space planning.

[P5-03] A study of Sanitation Management Knowledge and Perfor­mance of Employees in Kitchen and Food and Beverage Departments in Deluxe Hotel

Bo-Ra-Mi Kim,Ra-Rae, Lee,Mi-Ho Lee,Sung-Jae Lee,Yu-Jin Cho,Hyun-Joo Yoon,Ki-Sun Yoon 한국식품영양과학회 2007 한국식품영양과학회 학술대회발표집 Vol.2007 No.10

`실버케어 전문가` 미래직업 연계형 STEAM 프로그램이 초등학생의 미래지향 시간관, 진로인식 및 과학적 태도에 미치는 영향

유미현 ( Mi Hyun Yoo ),최정진 ( Jung Jin Choi ),박문숙 ( Mun Sook Park ),채수진 ( Su Jin Chae ),김보라 ( Bo Ra Kim ),손미현 ( Mi Hyun Son ),임은경 ( Eun- Kyong Lim ),유화수 ( Hwasoo Yu ),서종원 ( Jong Won Seo ),김주미 ( Ju Mi Kim 경북대학교 과학교육연구소 2017 科學敎育硏究誌 Vol.41 No.1

이 연구의 목적은 `실버케어 전문가` STEAM프로그램을 개발하고 초등학교에 적용하여 효과를 알아보는 것이다. 이 연구를 위해 경기도 소재 초등학생 110명이 참여하였다. 54명은 실험 집단으로, 56명은 비교집단으로 배치하였으며 프로그램 적용 전후에 미래지향 시간관, 진로인식, 과학적 태도 검사를 실시하였다. 본 연구에서 얻어진 결과는 다음과 같다. 첫째, `실버케 전문가` STEAM 프로그램을 적용한 실험집단 학생의 미래지향 시간관 전체 점수와 2개 하위영역 모두에서 비교집단에 비해 유의미하게 향상되었다(p<.05). 둘째, `실버케어 전문가` STEAM 프로그램을 적용한 실험집단 학생의 진로인식 전체 점수와 4개 하위영역 점수가 비교 집단에 비해 유의미하게 향상되었다(p<.05). 셋째, `실버케어 전문가` STEAM 프로그램을 적용한 실험집단 학생의 과학적 태도 전체 점수와 7개 하위영역 점수가 비교집단에 비해 유의미하게 향상되었다(p<.05). 넷째, `실버케어 전문가` STEAM 프로그램에 대한 실험집단 학생의 만족도를 조사한 결과 `나는 과학기술 분야와 관련된 직업에 대한 관심이 생겼다`라는 항목에서 가장 높은 긍정적 인식을 보여주었다. 결론적으로 본연구에서 개발 적용한 STEAM 프로그램이 초등학생의 미래지향 시간관, 진로인식, 과학적 태도를 향상시키는 데 효과적임을 시사한다. The purpose of this study was to develop `Silver Care Expert` STEAM Program for the elementary students and investigate the effects of the program on creative thinking activity, scientific attitude and leadership. Participants were 110 elementary school students. Before and after the program, the participants were asked to take the test about future time perspective, career awareness and scientific attitude. The major results of this study were as follows. First, the total score of experimental group`s future time perspective and all 2 sub-domains was significantly improved than those of comparative group(p<.05). Second, total score of experimental groups` career awareness and all 4 sub-domains were significantly increased than those of comparative group after the STEAM program(p<.05). Third, the total score of experimental groups` scientific attitude and all 7 sub-domains were significantly improved than those of comparative group(p<.05). Fourth, according to students` post-program opinions, experimental group students showed very positive perception like that science class was very interesting and they became interested in science and technology. In conclusion, `Silver Care Expert` STEAM Program was very effective to improve elementary students` future time perspective, career awareness, scientific attitudes.

전문적학습공동체에 관한 이론적 탐색에 관한 연구

유미라(Mi Ra Yu),김제현(Je Hyun Kim) 한국지방교육경영학회 2020 지방교육경영 Vol.23 No.3

본 연구는 문헌분석을 활용하여, 전문적학습공동체 개념적 이해에 초점을 맞추어 전문적학습공동체에 대한 이론적 탐색을 목적으로 한다. 첫 번째로, 전문적학습공동체 도입배경 측면에서 전문적학습공동체는 학습조직이라는 용어에서 태동하였으며, 학습조직의 공통적인 특징으로서 1) 의도하는 목적, 2) 집단적이고 지속적인 학습, 3) 질 높은 집단사고 과정의 중시는 학습공동체에 대한 접근 방향 혹은 시각을 제시해 주는 측면으로 이해되어야 한다. 두 번째로, 개념적 용어 사용 측면에서, 교사학습공동체와 전문적학습공동체라는 완전히 구분되는 별개의 용어라고 이해되기보다는, 강조점을 달리하는 유사 용어로 보는 것이 타당하다. 세 번째로, 전문적학습공동체 개념과 관련한 쟁점 측면에서 공동체/전문성/학습 등 3가지 사안으로 구분하여 살펴보았다. 우선, 공동체의 범위 상 지역사회 차원의 공동체를 지향할 필요가 있다. 다음으로, 교사전문성 개념은 교직 재개념화 측면과 연계된 논의가 필요하다. 마지막으로 공동체적 학습이 추구하는 범위는 학교 체제와 문화의 재구조화 차원까지 폭넓게 규정될 필요가 있다. 결론적으로, 전문적학습공동체를 운영한다는 것은 단위학교 내 교수-학습 차원의 교사협의회 수준보다는 보다 성숙한 전문적학습공동체를 추구하기 위해서 지역사회 차원의 지역공동체를 지향할 필요가 있다. This study aims to theoretically search the professional learning community, focusing on the conceptual understanding of the professional learning community, using literature analysis. First, in terms of the background of introduction of the professional learning community, the professional learning community was born in the term of a learning organization, and as a common characteristic of a learning organization, 1) intended purpose, 2) collective and continuous learning, 3) a high-quality group thinking process. The importance of ethics should be understood as an aspect that suggests a direction or perspective on the learning community. Second, in terms of the use of conceptual terms, it is reasonable to see them as similar terms with different emphasis rather than to be understood as completely separate terms of teacher learning community and professional learning community. Third, in terms of issues related to the concept of a professional learning community, it was divided into three issues: community/specialty/learning. First of all, it is necessary to aim for a community at the community level in terms of the scope of the community. Next, the concept of professionalism needs to be discussed in connection with the reconceptualization aspect of the teaching profession. Lastly, the scope of community learning needs to be broadly defined to the level of restructuring the school system and culture. In conclusion, to operate a professional learning community, it is necessary to aim for a local community at the local level in order to pursue a more mature professional learning community than at the level of a teacher council at the level of teaching-learning within a unit school.

특급 호텔 조리 식음료 종사자의 위생 관리 인지도 및 수행도에 관한 연구

김보라미(Bo-Ra-Mi Kim),이라래(Ra-Rae Lee),이미호(Mi-Ho Lee),이성재(Sung-Jae Lee),조유진(Yu-Jin Cho),윤현주(Hyun-Joo Yoon),윤기선(Ki-Sun Yoon) 동아시아식생활학회 2007 동아시아식생활학회지 Vol.17 No.6

This study was conducted to assess the current status of food safety/sanitation training programs, including HACCP, for kitchen and hall employees at major hotels, as well as how differently the training can affect the employees' recognition and performance of food safety/sanitation management in areas related to the facility, food, and their personal hygiene. A questionnaire for assessing the recognition and performance of sanitation management was developed and distributed to 430 employees currently working in the kitchens and halls of 5 hotels located in Seoul, Korea. A total of 324 questionnaires (kitchen: 138, hall: 186) were subjected to frequency analysis, chi-square tests, one way ANOVA, and Pearson correlation analysis using SPSS/windows software. Ninety-one percent of the respondents had received food safety/sanitation training, which was conducted by a hygienist or a cook once a month. However, only 55% of the respondents had HACCP training. The employees that did not have HACCP training had lower recognition scores than those who had HACCP training, especially in the washing procedures for tablewares, handwashing tools, cross contamination, reheating, and HACCP definitions. Trained, full-time employees received significantly higher recognition and performance scores than untrained, contract, or part-time employees. Significant differences in the recognition and performance scores were found among the employees of the 5 different hotels, indicating various levels for the outcome of their sanitation training. In addition, Pearson's correlation analysis confirmed that the recognition and performance scores were significantly correlated (r=0.473, p<.001). This study indicates that hotel foodservice employees must receive systematic food safety/sanitation training, including HACCP, which provides the foundation for safe foodservice operations.

표준화된 간호진단 및 문제와 NANDA-I 교차분석: 4개 상급종합병원 사례를 중심으로

송미라 ( Song Mi Ra ),심소연 ( Shim So Yun ),김대성 ( Kim Dae Sung ),이경순 ( Lee Kyung Soon ),이유나 ( Lee Yu Na ),원미숙 ( Won Mi Suk ) 병원간호사회 2020 임상간호연구 Vol.26 No.3

Purpose: To explore the scope and method of applying standardized nursing terminologies to nursing diagnosis and problems used in nursing practice. Methods: A descriptive study was done with a retrospective analysis of the nursing records of 141,420 patients that were hospitalized in 4 tertiary hospitals. The nursing diagnosis and problems collected from the records were standardized, and the standardized nursing diagnosis and problems cross mapped with NANDA-I, confirmed in a nursing focus group. Results: 65 (67.7%) of the 96 standardized nursing diagnosis and problems were equal with NANDA-I and included in the 10 domains of NANDA-I. Among 86 nursing diagnosis and problems excluded from the cross mapping with NANDA-I, the 63 terms (73.3%) related to surgery/procedure were the most common. Conclusion: It is meaningful that multi-tertiary hospital nursing diagnosis and problems were standardized and cross mapping with standard nursing terminologies was performed. As for the method of applying standardized nursing terminologies in nursing practice, it is appropriate to use several standardized nursing terminologies complementarily.