금피복된 임플란트 보철용 유지나사의 예비하중 및 풀림회전력에 관한 연구

정창모,황희성,전영찬,최설희 大韓齒科器材學會 2000 대한치과재료학회지 Vol.27 No.3

The purpose of this study was to compare the preload and the removal torque produced when using gold coated prosthetic retaining screws (Gold-Tite retaining screws) and non-coated screws(gold screws) repeatedly and to evaluate effects of a thin pure gold coating on screw stability. Following connection of the conical abutment to implant fixture using 20 Ncm of torque applied by a torque gauge, fastened the strain-gauged gold cylinder to conical abutment with gold screw, Gold-Tite retaining screw using 10Ncm. Then, preloads and removal torques were measured, screws tightened and loosened 8 times repeatedly. All experiments were performed under dry and wet condition. The results obtained were summarized as follows : 1. For gold screw group, no significant differences existed in the preload and the removal torque according to trials in both conditions(p>0.05). 2. For Gold-Tite retaining screw group, no significant differences existed in the preload according to trials in both conditions(p>0.05). However, the removal torque decreased at the second trial and incresed, after then(p<0.05). 3. In comparison of preloads according to trials, the preload in dry condition was greater than in wet condition only for Gold-Tite retaining screw group after the fourth trial(p<0.05). However, no significant differences were found between gold screw group and Gold-Tite retaining screw group(p>0.05). 4. In comparison of removal torque according to trials, the removal torque of gold screw group was greater than of Gold-Tite retaining screw group in dry condition at the second, third trial(p<0.05). At the other trials, no significant differences were found among the experimental groups(p>0.05).

정신지체특수학교 직업교육 혁신을 위한 교사참조요목 개발

박희찬,정민호 국립특수교육원 2005 특수교육연구 Vol.12 No.1

이 연구는 정신지체특수학교의 직업교육을 혁신하기 위해 교사참조요목을 개발하는데 목적이 있다. 이를 위하여 제7차 특수학교 교육과정의 하나인 기본교육과정의 직업교육, 전환교육, 그리고 지원고용 관련 문헌을 분석하여 교사참조요목의 초안을 마련하였고, 6명으로 구성된 직업교육 전문가 집단의 검토를 거쳐 5개영역에서 44개 문항을 개발하였다. 이 문항의 중요성에 대하여 중등부가 있는 전국 정신지체 특수학교 직업교사를 대상으로 조사연구를 실시하였다. 조사연구는 교사참조요목의 각 항목에 대한 중요성을 5점 척도의 조사지 형태로 만들어 실시하였고, 71개 학교에서 조사지가 회수되었다. 전체 조사문항에 대한 신뢰도로 Cronbach α는 .95였다. 조사결과, 교사참조요목의 교육과정은 모두 6개의 항목으로 구성되었고, 평정 점수는 4.18~4.41, 평균 점수는 4.34이었다. 교육방법은 16개의 항목에 평정점수는 3.90~4.65, 평균점수는 4.26이었다. 교육인력은 11개의 항목에 평정점수는 3.92~4.73, 평균점수는 4.31이었다. 교육시설은 6개의 항목에 평정점수 4.39~4.62, 평균점수 4.51이었다. 교육지원은 5개의 항목에 평정점수는 4.49~4.76, 평균점수 4.61이었다. 마지막으로 교사참조요목에 대한 논의와 활용 방안 개발, 현장 특수학교에서의 적용 사례 제시 등 후속연구 방안이 제안되었다. The purpose of the study was the development of teachers' reference inventory for renovation of vocational education of special schools for students with mental retardation. To investigate the purpose, the study reviewed Vocational Education Teachers' Book in 7th Basic Curriculum and literatures related to transition as well as supported employment. As a teachers' inventory, 44 items were developed in five areas based on the literature review and professionals discussion. Then, the importance of the 44 items were evaluated using 1 to 5 Likert scale by vocational special education teachers in 71 special schools among 73 special schools for students with mental retardation. The Cronbach's αof the inventory was .95. The first area, vocational education curriculum was composed of 6 items and evaluated from 4.18 to 4.41, with mean of 4.34. The second area, vocational educational method was composed of 16 items and evaluated from 3.90 to 4.65, with mean of 4.26. The third area, vocational educational personnel was composed of 11 items and evaluated from 3.92 to 4.73, with mean of 4.31. The fourth area, vocational educational facility was composed of 6 items and evaluated from 4.39 to 4.62, with mean of 4.51. Finally, the educational support for vocational education area was composed of 5 items and evaluated from 4.49 to 4.76, with mean of 4.61. The study suggested further research on the application method of the teachers' inventory and effective uses of the inventory in special schools to renovate vocational education.

직장암환자에서 복회음병합절제술(Miles' operation) 후 발생한 지속적인 배뇨장애의 치료

박희석,김기찬,정호중 고신대학교 의학부 1998 高神大學校 醫學部 論文集 Vol.13 No.1-2

Bladder dysfunction is one of the serious postoperative complications after rectal cancer surgery. To get sufficient objective data and factors for adequate management of bladder dysfunction following rectal cancer surgery, we reviewed medical records of 122 patients who had abdominoperineal resection of rectum (Miles' operation) for rectal cancer. The incidence of bladder dysfunction in 122 rectal cancer patients was 18.9 percent (23 patients). Among 23 patients with bladder dysfunction, 10 patients were referred to our rehabilitation service and their bladder was areflexic type neurogenic bladder at referred time. In 10 patients referred to our rehabilitation service, 8 patients(80.0% got the balanced bladder and 2 patients(20.0% ) failed, and the interval between beginning of bladder training and establishment of balanced bladder in 8 patient was 13.4±6.8 days. In 13 patients did not referred to our service, only 3 patients(23.1% ) got the balanced bladder and 10 patients(76.9%) failed. To improve the life quality of the rectal cancer patients with neurogenic bladder following abdominoperineal resection of rectum, early proper rehabilitative managements including bladder training were should be given.

만성 강박장애 환자의 정서처리 특성 : 정신분열병 환자 및 정상인과의 비교

석정호,김재진,전종희,이홍식,안석균,이은,김찬형 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : Obsessive compulsive disorder (OCD) tends to take chronic course as schizophrenia. Researchers reported that OC patients had idiosyncratic sensitivity to threat-related information, while schizophrenic patients were reported to have affec-tive blunting. We hypothesized that there might be a difference in emotional response between OCD and SPR in cronic phase. Methods : Eight different emotional tasks were done by 25 healthy controls, 21 OCD patients and 25 SPR patients. Visual stimuli were made by pairing two words or pictures. Four kinds of emotional stimuli (positive, negative, combined and neutral)were presented to subjects through monitor and they were asked to report their subjective feelings by pushing mouse button, In the combined condition, a pair of positive words (or pictures) and negative words (or pictures) were presented simultaneously. The responses and response time were recorded and analyzed using SPSS 9.0 package. Results : In the negative condition, OCD group didn't show any deficit compared to healthy group. But SPR group showed significantly lower appropriate response rate than healthy group, In the combined condition, OCD and healthy control group Showed 'negativity bias' which SPR group didn't show. In the positive condition, however, OCD and SPR groups did show Significantly lower appropriate response rate than healthy controls. Conclusion : Our results suggested that OCD patients may not have deficits in the processing of negative emotion even in the chronic phase but to have a specific deficit in positive emotion. This result supports the 'threat-relatedness hypothesis' on attentional bias of OCD.

분편 인플루엔자백신(split influenza vaccine)의 임상효과 및 면역원성에 관한 연구

우흥정,김동림,정희진,천병철,이주연,안정배,김지희,박찬,신영규,김우주,김민자,박승철 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 : 아단위 인플루엔자 백신 접종 후 백신의 인플루엔자 예방효과, 인플루엔자 방어 항체형성, 인플루엔자 백신의 안전성을 조사하고자 하였다. 방법 : 총 571명을 대상으로 인플루엔자 백신 접종을 하였고, 이들 접종자에서 인플루엔자 양질환의 이환을 조사하여 인플루엔자 백신의 인플루엔자예방효과를 알아보았고, 백신의 접종 전 및 접종 4주 후 혈청에서 혈구응집억제물(Hemagglutination Inhibition : HAI) 항체 검사를 실시하여 백신의 방어항체생성을 조사하였고, 백신의 안전성을 알아보기 위해 백신접종 후 1주일 이내의 부작용을 조사하였다. 결과 :백신 접종군과 백신 비접종군에서 인플루엔자 양 질환의 이환을 조사한 결과 접종군 28.35%, 비접종군 35.88%으로 나왔으며, p 값이 0.001로 통계적으로 접종군에서 유의하게 낮았고, 인플루엔자 양 질환의 예방 효과는 20.97%를 보였다. 백신의 방어항체 형성의 평가를 위해 유럽의 인플루엔자 백신 허가 기준을 조사하였는데 B/Guangdong/5/94균주의 백신접종 후 항체가 40이상의 비율을 제외한 다른 기준은 모두 만족 시켰다. 부작용은 전체 조사자 521명중 149명(29%)으로 주로 접종 부위의 국소 부작용을 호소했고, 전신 부작용은 2% 내외였으며 특별히 심각한 부작용은 발견되지 않았다. 결론 : 분편 인플루엔자 백신은 인플루엔자양질환의 예방과 방어항체생성에 효과 있으며 안전한 것으로 사료된다. Background : The safety and effectiveness of influenza vaccine are well known in developed country. The influenza vaccination has been recommended as one of the tentative immunization schedule for indicated persons since 1997 in Korea. But there are still no available data about them, even though nearly 5 million doses of influenza vaccine were used in 1997-1998 season. So it is immediately needed to investigate the safety. efficacy and immunogenicity of influenza vaccine among Korean. Methods : We studied the clinical efficacy of influenza vaccine by monitoring Occurrence of influenza-like illness in influenza risk group(vaccination ; 300, non-vaccination; 215) from December in 1997 to March in 1998. We used the split quadrivalent influenza vaccine containing 15 microgram of hemagglutinin of A/Beijing/262/95(HlNl), A/Wuhan/359/95(H3N2), B/Mie/1/93 and B/Guangdong/5/94. Hemagglutination inhibition(HA1) antibody titers were determined before immunization and 1 months after vaccination And we evaluated adverse effect of influenza vaccination at 7 days after vaccination. Results : Influenza vaccination was associated with si@icant reductions in influenza-like spptoms(vaccination group; 28.35%, non-vaccination group, 35.88%, p=0.001). The preventive effect of influenza-like i3lne.s among influenza risk goup was 20.97%. And immunogenicity of influenza A and B exceeded all of the European licensure criteria for immunogenicity except postvaccination proportion of titers 240 of B/Guangdong/5/94 strain. And the adverse effects were mainly local injection site problem and no serious adverse effect was noted. Conclusion : Split influenza vaccine is safe, inmunogenic and eff'tive in influenza risk group in Korea.

직장암환자에서 복회음병합절제술(Miles' operation)후 발생한 지속적인 배뇨장애의 치료

박희석,김기찬,정호중 高神大學 醫學部 1998 高神大學醫學部 論文集 Vol.13 No.1-2

위발성 위장관 악성림프종 환자에서 항암치료의 효과

김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

ILP 프로세서에서 2-단계 데이터 값 예측기의 Aliasing에 대한 효과

박희룡,전병찬,이상정 순천향대학교 부설 산업기술연구소 1998 순천향 산업기술연구소논문집 Vol.4 No.2

To exploit instruction level parallelism(ILP) in ILP processor, it is necessary to overcome the limits of data dependency among instructions. The data value prediction is a method to remove the limitation. In this paper, two-level data value predictor and hybrid data value predictor are studied. And the performance of those schemes are compared and analyzed. Also, the effects of aliasing on PHT(Pattern History Table) are measured and analyzed. As a result of experiment, it is shown that is there ware occurred aliasing of about 88%-98% in two-level and hybrid predictor. But the aliasing's hit ratio is reduced about 50% when XOR was applied on PHT.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

고정화 미생물을 이용한 페놀화합물의 분해에 관한 연구

송미정,김종신,원찬희 全北大學校 附設 都市및環境硏究所 1997 都市 및 環境硏究 Vol.12 No.1

Phenolic compounds are toxic and persistent material in the environment, and exhibit objectional tastes and odors. They are commonly found in wastes from the petroleum refining industry, coke-making industry, chemical plants and resin manufactures. The experimental treatment study of phenolic wastewater using immobilized system of Pleurotus cornucopiae and Lentinus edodes was performed under the conditions that the influent phenol concentration 1,000㎎/ℓ, hydraulic retention time 4hr ∼ `0hr, filling rate of immobilized pellets 10∼20%. The treatment system used in this study gives better performance with a shorter hydraulic retention time than the activated sludge process. In the operational condition of influent phenol concentration 1,000㎎/ℓ, 20% of filling rate with immobilized Pleurotus cornucopiae and Lentinus edodes, the national discharge limit of effluent("Na" zone, less than phenol 3㎎/ℓ) was satisfied with less than 10㎏-COD_cr/㎥·day.