Control of morphology and physicochemical properties of amylose- based nanoparticles through molecular complexation with fatty acids

Dahee Lim,Young-Rok Kim 한국산업식품공학회 2023 학술대회 및 심포지엄 Vol.2023 No.11

Control of morphology and physicochemical properties of starch nanoparticles through molecular complexation with fatty acids

Dahee Lim,Young-Rok Kim 한국산업식품공학회 2023 학술대회 및 심포지엄 Vol.2023 No.04

Evidence for Protective Effects of Coffees on Oxidative Stress-induced Apoptosis through Antioxidant Capacity of Phenolics

Lim, Dahee,Kim, Wooki,Lee, Mi-Gi,Heo, Ho Jin,Chun, Ock K.,Kim, Dae-Ok 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.6

This study evaluated total phenolics, total flavonoids, and antioxidant capacity of randomly selected regular and decaffeinated coffees commercially available in Korea and their protective effects in human hepatic epithelial HepG2 cell line against oxidative stress. All coffees tested exhibited potent antioxidant capacity in chemical systems and, consequently, significant protection of cells from oxidative stress in vitro in a dose-dependent manner. In particular, $H_2O_2$-induced apoptosis as evaluated by annexin V staining and flow cytometry was prevented by coffee extracts, resulting in the enhanced cell viability. Of interest, the content of total phenolics and flavonoids in coffees demonstrated a positive correlation with antioxidant capacity, indicating that the antioxidant capacity of coffees may be attributed to those phytochemicals. In accordance with previous studies, caffeoylquinic acid (CQA) and its derivatives including 3-CQA, 4-CQA, 5-CQA, 3,4-diCQA, 3,5-diCQA, and 4,5-diCQA were identified as phenolic phytochemicals by a reversed-phase HPLC, with 5-CQA being a major component. Taken together, the present study demonstrated protective effects of regular and decaffeinated coffees on cells in vitro against overwhelming oxidative stress due to richness in phenolics, especially CQA and its derivatives. Coffees, regular or decaffeinated, may serve as a good source of health-beneficial phytochemicals in diet.

대졸자의 취업성과 결정요인에 관한 연구

임다희(Lim, Dahee),조일형(Cho, Ilhyeong),권기헌(Kwon, GiHeon) 경기연구원 2014 GRI 연구논총 Vol.16 No.3

The fluctuating economic condition in Korea renders it difficult to find a decent job or a mere employment. The job market became a field of competition where those who have the required capabilities or capacities are at the advantage. Job seekers in Korea were daunted with the spec phenomenon--impressive credentials--that corporate recruiters require from an applicant Thus, in-school-youths have high propensity in engaging into further studies and other activities such as special classes on English--aimed at getting a high English proficiency score--either domestic or abroad, internship programs, volunteer works, and among others. Enhancing the personal spec or to acquire various and numerous certificates and licenses before landing to a certain job entails financial, emotional, and intellectual investment. Therefore, in this study, we seek to analyze the causal impact of determinant variables such as university credentials (i.e., degree, TOEIC score, etc.), job training (i.e., participation in employment camp), and employment plan on the university students perception on wage and job satisfaction. Results of the analysis provides that university credentials--double major and TOEIC--and job training--participation in employment camp--for 4-year college graduates gave a positive impact on wage. Second, the university credentials, specifically on course grades, positively influence job satisfaction irrespective of group category; while double major and TOEIC score is only significant for 4-year college graduates. The job training especially participation on employment camp influenced 2-3-year college graduates job satisfaction. Lastly, employment plan of 4-year college graduates (i.e., time and objective) is positively and significantly related with job satisfaction. Based on the results and analysis of the study, we will be able to offer specific policy recommendations that can help job seekers especially in-school-youths boost employment opportunity while attending school.

정책결정에 있어서 Kingdon의 다중흐름모형의 실증적 접근 -한국의 대외원조 정책을 중심으로-

임다희 ( DaHee Lim ),권기헌 ( GiHeon Kwon ) 한국정책학회 2015 韓國政策學會報 Vol.24 No.1

본 연구는 Kingdon의 다중흐름 모형을 적용하여 한국의 ODA 지원금액 결정에 대하여 살펴보았다. 다중흐름 모형을 정책의제설정 및 정책결정과정을 분석하는 모형으로써 합리모형, 만족모형, 점증모형, 쓰레기통 모형과 유사한 위치를 지니는 정책모형으로 평가받아왔다. 특히, 국내에서는 Kindgon의 다중흐름 모형이 많이 활용되어왔으며, 다중흐름 모형을 활용한 대부분의 연구들은 사례연구로 수행되어 왔다. 이는 다중흐름 모형이 본래 사례연구를 중심으로 이론적 틀이 구성되었기 때문일 수 있다. 하지만 다중흐름 모형을 실증적으로 검증한 Travis and Zahariadis(2002)의 연구를 통해서 살펴볼 수 있는 바와 같이 다중흐름 모형도 실증적인 접근이 가능함을 확인할 수 있다. 이에 본 연구에서는 Kingdon의 다중흐름 모형을 실증적으로 접근하여 검증하고자 하였다. 특히, 다양한 흐름들이 커플링(coupling)되어 정책의 창이 열리고, 정책결정으로 이어지는 커플링(coupling) 효과를 통계적으로도 검증할 수 있는지에 대한 분석을 실시하였다. 분석결과를 요약하면, 다중흐름 모형의 커플링(coupling) 효과는 존재하는 것으로 나타났다. 커플링(coupling) 효과를 살펴보기 위하여 각 흐름들 간의 독립적인 영향력에 대한 분석과 커플링 효과를 포함한 분석으로 총 2차례의 분석을 실시하였다. 분석결과 커플링 효과를 포함한 두 번째의 분석에서 영향력이 큰 것으로 나타났다. 또한, 첫 번째 분석에서는 유의미성을 확인할 수 없었던 변수들이 커플링 효과를 주었을때에 통계적 유의미성을 확인할 수 있었다. 하지만 본 연구는 종속변수에 미치는 독립변수들이 ODA에 미치는 영향력을 검증하기보다 다중흐름 모형의 커플링 효과를 실증적으로 검증하여 다중흐름 모형의 이론적·방법론적 확장을 하였다는 데에서 연구의 의의가 있을 수 있다. Employing Multiple Streams Model, proposed Kingdon, this research examined the decision-making mechanism regarding budgeting of Korean O.D.A. (Official Development Assistance) policy. Many scholars have recognized Kingdon’s model as an influencing theory as rational model, satisfying model, incremental model, and garbage can model. Especially, the policy stream model has been more prevailing research framework in Korea. However, most of studies, employing his theory, were case-study, since the model was suggested by evidences which were collected from many policy cases. While few research tested the model empirically, Travis and Zahariadis(2002) confirmed statistical possibilities of applications of the theory. In this context, this study tried to probe the stochastic possibilities or significances of the multiple streams model. In addition, we investigated coupling effects in the process of Korean O.D.A. policy decision-making. According to the theory, multiple streams open the policy window after coupling of three streams, and the coupling strongly affects policy decision-making. We confirmed that there are coupling effects of the multiple streams in the policy process. In order to detect the effects, we scrutinized the independent effects of each stream separately from analysis of coupling effects. The findings are that coefficient on the analysis that contained both the multiple streams and the coupling effects is positive and statistically significant. This research has implications that empirical test on the effects of coupling in the policy stream model to extend theoretical and methodological framework of the model.

Anti-inflammatory Efficacy of Fermented Artemisia capillaris Thunb. with Lactococcus lactis, Streptococcus thermophilus and Lactobacillus delbrueckii

Dahee Kim,Sooah Jeong,Chaewon Park,Huijeong Jeong,Beong Ou Lim 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

Artemisia capillaris Thunb. (ACT) is a plant of the sagebrush family and is known as a highly self-sustaining plant. It has been used as a medicine since a long time ago, and it is so effective that it is used as a treatment in many places. It helps skin elasticity, is effective in dieting, and helps to inflammation. ACT was extracted through hot water extraction method. ACT was fermented at 37°C for 24 hours using Lactococcus lactis, Streptococcus thermophilus and Lactobacillus delbrueckii. Then, the antioxidant activity was measured using the DPPH and ABTS assays. Samples of fermented ACT were treated in RAW 264.7 cells for 18 hours and then an experiment to measure cellular viability and NO production was conducted. Additionally, western blot and RT-PCR were performed to determine the expression level of anti-inflammatory-related proteins. As a result, it was verified that the fermented ACT has an antioxidant and anti- inflammatory effect. From the above results, we may suggest that fermented ACT has Antioxidant and anti-inflammatory properties. It can be used not only as a medicinal herb, but also as part of a functional food.

Study on the emission characteristics of microplastics during laundry processes

Dahee An,Hyunwoo Lim,Myunghee Kwon,Hyen-Mi Chung,Yu-sik Hwang,Jaewoong Lee 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.10

토픽모델링을 활용한 다국어 관광 리뷰 분석

Dahee Kim,Jiwon Lim,Kangwoo Lee,Soon-Goo Hong 융합관광콘텐츠학회 2022 융합관광콘텐츠학회 학술대회 발표집 Vol.2022 No.-

아민 옥사이드 양쪽성 계면활성제 첨가가 리포좀 특성에 미치는 영향에 관한 연구

모다희 ( Dahee Mo ),이수민 ( Sumin Lee ),이주연 ( Juyeon Lee ),한동성 ( Dongsung Han ),임종주 ( Jongchoo Lim ) 한국공업화학회 2016 공업화학 Vol.27 No.3

본 연구에서는 pH 변화에 따른 양쪽성 계면활성제 첨가가 리포좀 특성에 미치는 영향에 관하여 살펴보았다. 이를 위하여 아민 옥사이드(amine oxide) 양쪽성 계면활성제를 합성하고 1H NMR, 13C NMR 및 FT-IR 분석을 통하여 구조를 규명하였으며, 계면활성제의 임계 마이셀 농도(critical micelle concentration, CMC) 및 표면장력 등의 계면 물성(interfacial property)을 측정하였다. 또한 제타 전위(zeta potential) 측정을 통하여 양쪽성 계면활성제가 양이온 계면활성제(cationic surfactant)에서 음이온 계면활성제(anionic surfactant)로 작용이 전환되는 등전점(isoelectric point)을 결정하였다. 이 결과를 바탕으로 등전점을 중심으로 한 pH 변화 및 아민 옥사이드 계면활성제의 탄화수소 사슬 길이가 리포좀의 평균 입자 크기 변화 및 제타 전위 등과 같은 안정성에 미치는 영향에 살펴보았다. 또한 pH 및 계면활성제의 탄화수소 사슬 길이 변화에 따른 및 리포좀과 계면활성제의 결합 정도(binding degree) 및 리포좀 막의 가변형성(deformability) 등의 측정을 통하여 리포좀 막의 유동성(fluidity) 변화에 미치는 영향을 이해하고자 하였다. In this study, zwitterionic surfactants were added to liposome systems at different pH conditions to understand the effect of surfactants on liposome characteristics. For this purpose, amine oxide surfactants having different hydrocarbon chain lengths were synthesized and the structure of the resulting product was elucidated by using 1H NMR, 13C NMR, and FT-IR. In addition, the physical properties of newly synthesized surfactants such as critical micelle concentration (CMC), surface tension and isoelectric point were measured. The stability characteristics of liposome systems including average particle sizes and zeta potentials were measured by varying pH and hydrocarbon chain lengths of an amine oxide surfactant. Effects of the pH and hydrocarbon chain length of an amine oxide surfactant on fluidity of a liposome membrane were also examined by measuring the deformability and the binding degree between the surfactant and liposome.

클러스터링 기법을 활용한 관광지 대표문장 추출

김다희 ( Dahee Kim ),이강우 ( Kangwoo Lee ),임지원 ( Jiwon Lim ),홍순구 ( Soon-goo Hong ) 한국정보처리학회 2021 한국정보처리학회 학술대회논문집 Vol.28 No.2

‘파리의 더러운 지하철’, ‘런던의 비싼 물가’ 등 관광지에 대한 몇 마디 말은 관광지를 직관적으로 이해하는데 도움을 준다. 관광지에 대한 직관적 평가를 파악하기 위해서 클러스터링 기법을 사용하였다. ‘주차’, ‘경치’, ‘시설’과 같은 다양한 라벨을 부여하여 클러스터링을 비교한 결과 ‘주차’, ‘경치’ 등 비슷한 문맥의 리뷰가 같은 클러스터로 묶인 것을 확인할 수 있었고, 각 분야의 문맥을 파악하기 위해 대표문장을 추출하였다. 각 분야의 대표문장은 해당 분야의 평가를 잘 파악할 수 있었고, 해당 분야의 만족도뿐만 아니라 불편사항 등을 이해하는데 도움을 준다.