A Combination of Scutellaria Baicalensis and Acacia Catechu Extracts for Short-Term Symptomatic Relief of Joint Discomfort Associated with Osteoarthritis of the Knee

Bahram H. Arjmandi,Lauren T. Ormsbee,Marcus L. Elam,Sara C. Campbell,Nader Rahnama,Mark E. Payton,Ken Brummel-Smith,Bruce P. Daggy 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.6

The extracts of Scutellaria baicalensis and Acacia catechu have been shown in previous studies to alleviate joint discomfort, reduce stiffness, and improve mobility by reducing the production of proinflammatory molecules over long periods of supplementation. The acute effects of intake of these extracts have not yet been investigated. Thus, we carried out a 1 week clinical trial to examine the extent to which UP446—a natural proprietary blend of S. baicalensis and A. catechu (UP446)—decreases knee joint pain, mobility, and biomarkers of inflammation in comparison to naproxen. Seventy-nine men and women (40–90 years old) diagnosed as having mild to moderate osteoarthritis (OA) consumed either 500 mg/day of the UP446 supplement or 440mg/day of naproxen for 1 week in a double-blind randomized control trial. Pain, knee range of motion (ROM), and overall physical activity were evaluated at the start and at the end of treatment. Fasting blood was collected to determine serum interleukins 1b and 6, tumor necrosis factor-a, C-reactive protein, and hyaluronic acid. The UP446 group experienced a significant decrease in perceived pain (P = .009) time dependently. Stiffness was significantly reduced by both treatments (P= .002 UP446, P = .008 naproxen). Significant increases in mean ROM over time (P = .04) were found in the UP446 group. These findings suggest that UP446 is effective in reducing the physical symptoms associated with knee OA.

Determination of the Best Sowing Time, Bulb Diameter and Intra-Row Spacing of Azarshahr Red Onion

Bahram Mirshekari,Mehrdad Yarnia,Farhad Farahvash,Mohammad Mobasher,Reza Biroonara 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

Intrusion detection for cloud computing using neural networks and artificial bee colony optimization algorithm

Bahram Hajimirzaei,Nima Jafari Navimipour 한국통신학회 2019 ICT Express Vol.5 No.1

This paper proposes a new intrusion detection system (IDS) based on a combination of a multilayer perceptron (MLP) network, and artificial bee colony (ABC) and fuzzy clustering algorithms. Normal and abnormal network traffic packets are identified by the MLP, while the MLP training is done by the ABC algorithm through optimizing the values of linkage weights and biases. The CloudSim simulator and NSL-KDD dataset are used to verify the proposed method. Mean absolute error (MAE), root mean square error (RMSE), and the kappa statistic are considered as evaluation criteria. The obtained results have indicated the superiority of the proposed method in comparison with state-of-the-art methods.

Metabolic Fingerprints by Nano-baskets of 1,2-Alternate Calixarene and Emulsion Liquid Membranes

Bahram Mokhtari,Kobra Pourabdollah 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.7

A novel approach for metabolite extraction and fingerprinting was introduced based upon the nano-baskets and emulsion liquid membrane-nuclear magnetic resonance (ELM-NMR) technique. The objective of this method is optimizing the fingerprints, minimizing the metabolic variation from analysis, increasing the likelihood differences, and obtaining the maximum extraction yield. Low molecular weight metabolites in rat serum were recovered by ELMs using 12 nano-baskets of calixarene, as both emulsifier and carrier. The yields of ELMs were optimized by the method of one-at-a-time. According to NMR data, the maximum metabolic variation was achieved using scaffold 4 (4 wt %), n-decane membrane, stirring rate of 300 rpm, treat and phase ratios of 0.3 and 0.8, respectively. The results revealed that some calixarenes tend to extract non-specific macromolecules; and repeatability of fingerprints for 7-mediated ELM was maximum and for 3-mediated ELM was minimum. The yield of extractions was obtained to be higher for n-decane and lower for carbon tetrachloride. Among different membranes, the fingerprints by chlorinated liquid membranes were more repeatable than using toluene or n-decane.

Pre-Aging Time Dependence of Microstructure and Mechanical Properties in Nanostructured Al-2wt%Cu Alloy

Bahram Azad,Ehsan Borhani 대한금속·재료학회 2016 METALS AND MATERIALS International Vol.22 No.2

This work is focused on the effect of pre-aging time on the properties of Al-2wt%Cu alloy processed by accumulative roll bonding (ARB) process. Following aged at 190 °C for 10 or 30 min, the samples were deformed up to a strain of 4.8 by the ARB process. The microstructure evolution was investigated by transmission electron microscope and electron backscattering diffraction analyzes. The results showed that the Al2Cu precipitates were formed with different sizes due to the different pre-aging times and the finer precipitates were more effective on the formation of high angle grain boundaries during the ARB process. The grain size of Aged-10 min and Aged-30 min specimens decreased to 400 nm and 420 nm, respectively, after 6 cycles of the ARB process. Also, the final texture after 6 cycles of the ARB process, shown in the {111} pole figure, were different depending on the starting microstructures. The mechanical properties of specimens were investigated by the Vickers microhardness measurements and the tensile tests. The results showed that the mechanical properties are affected by the starting microstructure. The mechanical properties of Aged-10 min specimen were different compared to Aged-30 min specimen due to the different size of the pre-existing precipitates. Although by continuing process, the precipitates were probably dissolved due to the heavy deformation.

Study of QTLs linked to awn length and their relationships with chloroplasts under control and saline environments in bread wheat

Bahram Masoudi,Mohsen Mardi,Eslam Majidi Hervan,Mohammad Reza Bihamta,Mohammad Reza Naghavi,Babak Nakhoda,Behnam Bakhshi,Mehrzad Ahmadi,Mohammad Taghi Tabatabaei,Mohamad Hossein Dehghani Firouzabadi 한국유전학회 2019 Genes & Genomics Vol.41 No.2

Introduction Some studies in wheat showed that awns may have a useful effect on yield, especially under drought stress. Up to this time few researches has identified the awn length QTLs with different effect in salinity stress. Objective The primary objective of this study was to examine the additive (a) and the epistatic (aa) QTLs involve in wheat awns length in control and saline environments. Methods A F7 RIL population consisting of 319 sister lines, derived from a cross between wheat cultivars Roshan and Falat (seri82), and the two parents were grown in two environments (control and Saline) based on an alpha lattice design with two replications in each environment. At flowering, awn length was measured for each line. For QTL analysis, the linkage map of the ‘‘Roshan × Falat’’ population was used, which included 748 markers including 719 DArT, 29 simple sequenced repeats (SSRs). Additive and pleiotropic QTLs were identified. In order to reveal the relationship between the identified QTL for awns length and the role of the gene or genes that it expresses, the awns length locus location and characteristics of its related CDS, gene, UTRs, ORF, exons and Introns were studied using ensemble plant (http://plant s.ensem bl.org/Triti cum_aesti vum). Furthermore, the promoter analysis has been done using NSITE-PL. Results We identified 6 additive QTLs for awn length by QTL Cartographer program using single-environment phenotypical values. Also, we detected three additive and two epistatic QTLs for awn length by the QTLNetwork program using multienvironment phenotypical values. Our results showed that none of the additive and epistatic QTLs had interactions with environment. One of the additive QTLs located on chromosome 4A was co-located with QTLs for number of sterile spikelet per spike in both environment and number of seed per spike in control environment. Coclusion Studies of the locus linked to the awns length QTL revealed the role of awn and its chloroplasts in grain filing during abiotic stress could be enhanced by over expression of some genes like GTP-Binding proteins which are enriched in chloroplasts encoded by genes included wPt-5730 locus.

The Status and Social Role of Women in Iran

Bahram Badiozamani 한양대학교 민족학연구소 2000 民族과文化 Vol.9 No.-

Phenology, Essential Oil Yield and Quality of Cumin (Cuminum cyminum L.) Affected by Sowing Dates and Plant Densities

Bahram Mirshekari 한국원예학회 2010 Horticulture, Environment, and Biotechnology Vol.51 No.5

Field experiments were conducted for evaluation of effects of sowing dates and plant densities on phenology and essential oil quality of cumin (Cuminum cyminum L.). The experiments were arranged as factorial based on randomized complete block design with sowing the dates of 26<SUP>th</SUP> March, 5<SUP>th</SUP>, 15<SUP>th</SUP> and 25<SUP>th</SUP> April, and densities as 25.0, 31.3, 41.7 and 62.5 plants.m<SUP>-2</SUP>. Results showed that the lowest growth period was on 25<SUP>th</SUP> April. Plants sown on 26<SUP>th</SUP> March had greater seed yield than those sown on later sowing dates. The earliest sowing date produced the largest seeds with a thousand seed weight of 3 g. The treatment of 26<SUP>th</SUP> March × 62.5 plants.m<SUP>-2</SUP> produced higher essential oil. Among tested independent variables, seed yield showed a significant effect on essential oil yield. Essential oil content improved 7.55 × 10<SUP>-3</SUP> mL.m<SUP>-2</SUP> per ㎏, increasing seed yield of cumin. Plant density did not show any considerable effect on the essential oil components of cumin. Delaying in sowing date caused a significant effect on cuminaldehyde concentration in essence; thus, a maximum value was obtained from 26<SUP>th</SUP> March and 5<SUP>th</SUP> April sowings. For successful seed production and higher essential oil quantity and quality, cumin must be sown until late March (26<SUP>th</SUP> March) with density of 62.5 plants.m<SUP>-2</SUP> in Tabriz region.

Proposing an Elliptic Equation for the Symmetrical Sag Vertical CurvesBased on Sight Distance in Highway

Bahram Shirini,Ali Abdi Kordani 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.12

The sight distance at night is one of the most important driving safety factors. Sag vertical curves are one of the important elements of roads, which require a sufficient sight distance at night. The headlight sight distance is used for determining the length of the sag vertical curves. Presently, the parabolic curve is mainly used in symmetrical sag vertical curves. The present study aimed to propose the elliptic curve as a new alternative for the parabolic curve. An elliptic equation is developed for use in vertical curve and sight distance of the sag elliptic vertical curve in nighttime is calculated based on the characteristics of the road geometry. Results indicate that contrary to the parabolic curve, the sight distance of the elliptic curve varies depending on the vehicle location and increases as the vehicle moves forward on the curve; therefore, driver sees the end of curve in elliptic curves much earlier than parabolic curves. The results also indicate that the sight distance of the parabolic curve is more than that of the elliptic curve in the shortest length after the curve beginning (up to 8% of the curve length) while the sight distance of the elliptic curve is more than that of the parabolic curve at the rest of the curve (at least 92% of the curve length). Based on the obtained results, for S > L, the stopping sight distances of the elliptic and parabolic vertical curves are equal.

Extraction of alkali metals using emulsion liquid membrane by nano-baskets of calix[4]crown

Bahram Mokhtari,Kobra Pourabdollah 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.12

Nano-assisted inclusion separation of alkali metals from basic solutions was reported by inclusion-facilitated emulsion liquid membrane process. The novelty of this study is the application of nano-baskets of calixcrown in the selective and efficient separation of alkali metals as both the carrier and the surfactant. For this aim, four derivatives of diacid calix[4]-1,2-crowns were synthesized, and their inclusion-extraction parameters were optimized including the calixcrown scaffold (13, 4 wt%) as the carrier/demulsifier, the commercial kerosene as diluent in membrane, sulphonic acid (0.2 M) and ammonium carbonate (0.4 M) as the strip and the feed phases, the phase and the treat ratios of 0.8and 0.3, mixing speed (300 rpm), and initial solute concentration (100mg/L). The selectivity of membrane over more than ten interfering cations was examined and the results revealed that under the optimized operating condition, the degree of inclusion-extraction of alkali metals was as high as 98-99%.