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( Moon Ho Kim ),( Heui June Ahn ),( Hyun Joong Kim ),( So Young Park ),( Su Jung Jung ),( Yongchel Ahn ),( Ho Suk Oh ),( Heui June Ahn ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Prophylactic cranial irradiation (PCI) is an essential treatment in limited- stage small cell lung cancer (SCLC) for reducing the incidence of brain metastasis (BM) and improving overall survival rates. In extensive stages, PCI is also recommended for those who show good performance. However, PCI is optional for elderly patients with SCLC due to its toxicity, and there is no specific upper age limit for the use of PCI. In this study, we performed an observational study in elderly SCLC patients above the age of 60 who were not receiving PCI. Methods: In total, 156 elderly patients (aged 60 or above) were diagnosed with SCLC between 2001 and 2009 from GangNeung Asan Medical Center. Of them, 104 were included and investigated retrospectively. Forty-Seven were lost to follow-up, two had BM at the time of initial diagnosis, and three had PCI. The median age of the patients at the time of diagnosis was 70.01 years. Of the patients, 91 (87.5%) were male and 13 (12.5%) were female. Results: Symptomatic BM was detected in 14 out of the 104 (13.5%). When analyzed by age group at diagnosis, the incidence of BM in the age ranges 60-64, 65-69, 70-74, and 75 and older were 23.8% (five out of 21), 17.6% (Six out of 34), 8.0% (Two out of 25), and 4.2% (One out of 24), respectively. Conclusions: This study shows that the incidence of BM in SCLC patients aged 60 and above was 13.5%, which is lower than among the whole SCLC population compared to previous studies. This study implies that there is a lesser incidence of BM as age increases. Therefore, when performing PCI, practitioners should be more concerned with elderly SCLC patients.
Optimum Port Investement with an Infinite Planning Horizon
안문석(MOON SUK AHN) 한국정보과학회 1977 정보과학회논문지 Vol.4 No.1
本 論文은 特定 항구에 있어서 그 港口를 利用하는 貨物量이 매년 끊임없이 增加하고, 同時에 計劃期間이 無限할 경우의 적정 투자시기와 投資規模를 결정하는 모델에 관한 것이다. 解法으로는 通信위성에 있어서의 最少費用投資問題를 다룬 스노우(Snow)의 모델이 港灣投資 결정에 맞도록 修正 補完되었고 실제적인 解法은 컴퓨터 시뮤레이숀 방법이 이용되었다. 지금까지의 항만투자 결정모델이 한 순간(one-shot) 모델이 特性을 띈 靜態 모델인데 반해, 本 모델은 적정투자의 時期와 規模를 動態的으로 다룰 수 있게 해 준다는 특징을 갖는다.