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채진호,윤원덕,김병호,기장서 한국동물분류학회 2017 Animal Systematics, Evolution and Diversity Vol.33 No.1
We firstly described a box jellyfish, Carybdea brevipedalia collected from the southern coasts of Korea. It is morphologically characterized by gastric phacellae, a special digestive system of cubozoan jellyfish, and velarium, the thin muscle flap forming the opening of the subumbrellar cavity. The phacellae are linear-shaped, comprising numerous cirri branched from multiple roots. Each root also has multiple numbers of cirrus bundles. Basis of velarial cannels parts into two branches in each octant of velarium. Its geographic distributions were limited to Jejudo and the middle-southern coasts where the organisms are seriously hazardous to bathers in summer. Numerous individuals and/or large-sized populations were observed specifically from beaches at Jeju-do, Namhae-do and a small fishing port of Namildae, while only a small amount of the individuals was observed in Gamak Bay, Jaran- Goseung Bay, and Geoje-do. We confirmed molecular identity of the Korean C. brevipedalia with comparison of nuclear ribosomal DNA sequences. Until now, Carybdea brevipedalia is the only cubozoan species reported to be distributed in Korean waters.
수장부 다한증에 제한적 교감신경절간 절단술의 장기 고찰
채진호(Jin Ho Chai),최봉춘(Bong Chun Choi),이영철(Yong Chul Lee) 대한통증학회 2001 The Korean Journal of Pain Vol.14 No.1
N/A Background: Conventional thoracoscopic sympathectomy or sympathicotomy is an effective method in treating localized hyperhidrosis; however, this may result in a postoperatively compensatory hyper- hidrosis or facial anhidrosis in the treatment of palmar hyperhidrosis. We modified the conventional sympathicotomy by limiting the extent of nerve transection (limited T3 sympathicotomy) since May 199S. However, there are many reports of a good short-term outcome of limited T3 sympathicotomy. Therefore, we reviewed long-term follow-up of limited T3 sympathicotomy based on outcomes analysis using a questionnaire. Methods: Fifty four patients with palmar hyperhidrosis underwent a limited T3 sympathicotomy between May 1998 and March 1999 and had a complete follow-up over two years using a questionnaire (the mean follow-up was 2.6 years). The patients' postoperative satisfaction was determined by their subjective responses to the questionnaires; the degree of compensatory hyperhidrosis, the effects on foot hyperhidrosis, gustatory hyperhidrosis and facial dryness, and recurrence, and patients satisfaction. Results: Of the total, 87% of patients had a compensatory hyperhidrosis and 3.7% of them were disabled. 31.5% of patients showed improvement in foot hyperhidrosis, while 68.5% of patients demonstrated no change or got worse. 31.5% of patients had gustatory hyperhidrosis and facial dryness and 22.2% of patients showed a mild palmar hyperhidrosis. The postoperative patients satisfaction was significantly in 96.3% of patients. Conclusions: The limited T3 sympathicotomy is a highly effective treatment of palmar hyperhidrosis and has a low rate of postoperative compensatory hyperhidrosis, gustatory hyperhidrosis, and facial dryness.
채승기 ( Seung-gi Chai ),고진호 ( Jin-ho Ko ),황재동 ( Jae-dong Hwang ),김기룡 ( Ki-ryoung Kim ) 한국정보처리학회 2007 한국정보처리학회 학술대회논문집 Vol.14 No.2
사회가 고령화, 초핵가족화 및 재난취약계층이 늘어나면서 요구호자에 대한 고품질 맞춤형서비스가 필요하게 되었다. 본 논문에서는 소방방재청의 24*365 긴급대응서비스에 IT첨단기술, 바이오·의료기술을 접목하여 언제 어디서나 고품격 맞춤형 서비스를 제공할 수 있는 U-119시스템 개념, 구축사례 및 발전방향에 대해 제시하고자 한다.
분열효모 핵공단백질인 Nup184의 기능에 필요한 부위 분석 및 SUMO 변성
채애리,장수연,윤진호,Chai, Ai-Ree,Jang, Soo-Yeon,Yoon, Jin-Ho 한국미생물학회 2012 미생물학회지 Vol.48 No.2
Nup188 단백질은 진화적으로 보존된 가장 큰 핵공단백질 중의 하나로 핵공복합체의 inner ring을 구성하는 인자이다. Nup188의 이종상동체인 분열효모 S. pombe의 Nup184 단백질은 영양분이 풍부한 완전배지(YES 배지)에서 정상적인 생장과 mRNA의 핵에서 세포질로의 이동에 필요하다. 본 연구에서는 ${\Delta}nup184$ 결실돌연변이를 YES 배지에서 배양할 때 보이는 생장지체와 mRNA export 결함을 상보하기 위해서 Nup184의 카르복시 부위(아미노산 잔기482에서 1628까지)가 필요함을 알아내었다. 또한 이 부위는 GFP-Nup184 융합단백질이 핵막에 위치하기 위해서도 필요하였다. 이 과정에서 S. pombe GeneDB (Sanger 연구소, 영국)에 등록되어 있는 Nup184의 열린읽기틀 (1564개의 아미노산 잔기로 된 단백질로 예측)이 우리가 얻은 염기서열 데이터에 비해 66개의 아미노산 잔기가 짧다는 것을 발견하였다. 이 카르복시-말단 부위는 Nup184의 기능에 반드시 필요하였다. 이외에도 Nup184 단백질이 세포 안에서 SUMO 변형되어 있음을 보였다. The Nup188 protein is one of the largest evolutionally conserved nucleoprins (Nups) that compose the inner ring of nuclear pore complex (NPC). The Nup184 protein, fission yeast Schizosaccharomyces pombe ortholog of Nup188p, is required for normal growth and mRNA export in nutrient-rich medium (YES). Here, we identified a carboxyl region (482 to 1628) of Nup184 protein that was enough to complement the defects of both growth and mRNA export when the ${\Delta}nup184$ knock-out mutant was grown in YES medium. This region is also required for localization of GFP-Nup184 fusion to the nuclear periphery. In addition, we found that ORF of Nup184 (predicted 1564 amino-acid protein) registered in S. pombe GeneDB (hosted by Sanger Institute, UK) is 64 amino-acid residues shorter than that predicted by our sequence data. This carboxy-terminal region is necessary for the functions of Nup184p. We further demonstrated that Nup184 protein was conjugated with SUMO in vivo.
국진호,채수량,송지남,서재현 대한이비인후과학회 2011 대한이비인후과학회지 두경부외과학 Vol.54 No.5
Paget’s disease is a localized bone disorder that affects widespread areas of skeleton characterized by increased bone remodeling. It is a chronic, progressive disease of unknown etiology. The pathologic process is initiated by hyperactive osteoclastic bone resorption followed by a compensatory increase in the osteoblastic new bone formation. New pagetic bones are disorganized and more susceptible to deformities and fractures. Paget’s disease can affect one or multiple bones in the systemic skeleton, including the temporal bone. We experienced a case of chronic otitis media combined with an external auditory canal stenosis due to Paget’s disease of the temporal bone. We report clinicopathologic features of this rare case.