Relationship between Cognitive Impairment and Depression in Dialysis Patients

정산,이영기,최선령,황성희,노정우 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.6

Purpose: Patients with chronic kidney disease frequently show cognitive dysfunction. The association of depression and cognitive function is not well known in maintenance dialysis patients. We evaluated cognitive impairment and depression, as well as their relationship in regards to methods of dialysis, maintenance hemodialysis (MHD) and chronic peritoneal dialysis (CPD). Materials and Methods: Fifty-six maintenance dialysis patients were recruited and their clinical and laboratory data were collected. The Korean version of the mini-mental state exam (K-MMSE) was applied to screen the patient’s cognitive function, while the Korean version of the Beck Depression Inventory (K-BDI) was used for depression screening. Results: The average age of the participants was 54.2±10.2 years; 29 (51.8%) were female. The average dialysis vintage was 4.2±3.8 years. The CPD group showed significantly higher K-MMSE score (27.8±2.9 vs. 26.1±3.1, p=0.010) and lower K-BDI score (12.0±8.4 vs. 20.2±10.4, p=0.003) compared with the MHD group. The percentage of patients with depression symptoms was higher in the MHD group (51.7% vs. 18.5%). There was a negative correlation between cognitive function and prevalence of depressive symptoms. Depression and education level were shown to be independent predictors for cognitive impairment in multivariate analysis. Conclusion: Cognitive impairment was closely correlated with depression. It is important to detect cognitive impairment and depression early in maintenance dialysis patients with simple bedside screening tools.

Donepezil 복용 후 발생한 구음장애

정산,백종삼 대한신경과학회 2001 대한신경과학회지 Vol.19 No.2

Ischemic Stroke among the Patients with End-Stage Renal Disease Who Were Undergoing Maintenance Dialysis

정산,이영기,권석범,황성희,노정우 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.5

Purpose: In spite of higher incidence of stroke in end-stage renal disease (ESRD) patients compared to general population, the risk factor for stroke which is specific to ESRD is not fully understood. The ESRD patients who develop stroke may have certain additional risk factors compared to ESRD patients without stroke. We used registered data of Hallym Stroke Registry to elucidate the factors which affect development of ischemic stroke among the dialysis patients. Materials and Methods: We recruited patients with acute ischemic stroke in ESRD patients undergoing maintenance dialysis. Dialysis patients without stroke were selected as control group with age and gender matching. We compared the demographic features,stroke risk factors, and laboratory findings in ESRD patients with or without ischemic stroke. Results: The total of 25 patients with ESRD developed ischemic stroke. Fifty ESRD patients without stroke were chosen as the control group. The mean age of acute ischemic stroke patients was 59.80±9.94 and male gender was 48%. The most common ischemic stroke subtype was small vessel occlusion (n=12), followed by large artery atherosclerosis (n=7). The patients with stroke had more frequent history of hypertension and higher systolic/diastolic blood pressure at the time of admission than the ESRD patients without stroke. Total cholesterol and LDL-cholesterol levels were significantly lower in the stroke group. In multivariate analysis, LDL-cholesterol was found to be the only risk factor for ischemic stroke. Conclusion: The results of our study reveal that LDL-cholesterol is associated with greater risk for ischemic stroke in the patients on dialysis.

정부 지원 기반의 벤처 캐피탈 그리고 IT벤처의 성장

정산,김태경 한국IT서비스학회 2020 한국IT서비스학회 학술대회 논문집 Vol.2020 No.-

소뇌 소경색의 임상 양상과 발병 기전

정산 대한뇌졸중학회 2001 Journal of stroke Vol.3 No.2

Background : In the cerebellum, small(〈2 cm in diameter)infarcts have recently been reported as having different pathogenic mechanisms from supratentorial small ischemic lesions. However, it is unclear only with simple MRI or conventional CT scan whether they are lacunar infarcts or borderzone infarcts. The purpose of this study was to elucidate the pathophysiological mechanism and the clinical nature of small cerebellar infarcts. Methods : We analyzed consecutive patients admitted to the Hallym stroke center between 1994 and 1999. Among them, we selected ischemic cerebellar stroke and classified them into large territorial, small non-territorial and mixed types according to their infarct sizes. We studied clinical and MRA findings and pathogenic mechanisms in each type of the cerebellar infarcts. Results : Forty-seven patients were selected for the study. Twenty-one cases were classified as large territorial infarcts, 18 patients as small non-territorial cerebellar infarcts. The Mixed form included 8 patients. Patients with large territorial infarcts and those with small cerebellar infarcts had similar risk factors, laboratory findings and clinical features. As for the causative mechanisms, small cerebellar infarcts had similar proportion of large artery disease(66.7% vs. 55.7%) and cardiac embolic source(16.7% vs. 28.6%) when compared to large territorial infarcts. Conclusion : Although the radiologic findings of small cerebellar infarcts resemble supratentorial lacunar lesion, the small cerebellar infarcts have heterogenous etiologies. Diagnostic studies and management of small cerebellar infarcts should be based on the understanding of these observations. Korean Journal of Stroke 2001;3(2): 124~130

24시간 혈압 감시를 통한 만성 뇌졸중 환자에서의 야간 혈압 강하 현상의 연구

정산,이병철,유경호,정승철,김성민,권기한,황성희 대한신경과학회 1996 대한신경과학회지 Vol.14 No.4

소셜 빅데이터 분석을 활용한 한국 야구 국가대표팀에 대한 인식 분석 : 2023 월드 베이스볼 클래식(World Baseball Classic)을 중심으로

정산,오응수 한국스포츠학회 2023 한국스포츠학회지 Vol.21 No.3

This study aims to understand the overall perception of the South Korean national baseball team in the 2023 World Baseball Classic (WBC) and provide insights for improving public perception and marketing strategies for the WBC tournament. Using the TextoM big data processing solution, various analyses were conducted on data collected from Naver, Daum, and Google during different WBC phases. The research findings are as follows: Firstly, keyword analysis revealed that before the WBC opening, the predominant keywords revolved around information about the South Korean national baseball team, training, broadcasting, while during the WBC tournament, the focus shifted to participating countries, players, match schedules, and results. After the WBC's conclusion, keywords were related to tournament information, the start of the professional baseball season, and team performance issues. Secondly, network visualization and CONCOR analysis unveiled distinct groupings during different phases. Prior to the WBC opening, there were four groups comprising the South Korean national baseball team, WBC match issues, training, and commentary. During the WBC tournament, five groups emerged, including the South Korean national baseball team, WBC match issues, match results, WBC opening, and national team retirements. After the WBC's conclusion, four groups surfaced, involving the South Korean team's performance, downturn, Asian Games preparation, and match issues. Based on these results, this study aims to contribute to public perception analysis research and the development of the domestic sports industry by suggesting improvements in public perception and WBC activation strategies.

피질증상 동반여부에 따른 선조-내포경색의 특징적 임상양상과 방사선학적 소견에 대한고찰 - 예비연구

정산 대한뇌졸중학회 2002 Journal of stroke Vol.4 No.2

Background : Striatocapsular infarction(SCI) is a well-known form of stroke, which produces various neurologic symptoms including cortical dysfunction. The aim of our study was to evaluate clinical and radiological findings of SCI according to the presence of absence of cortical dysfunctions. Methods : We analyzed 44 patients with SCI and divided them into two groups according to their initial clinical manifestations. Those who showed cortical symptoms and signs were regarded as cortical type SCI and the others were classified as non-cortical type. We compared the stroke risk factors, laboratory data, clinical features and MRI/MR angiography findings between the two groups. Results : Patients with cortical type SCI and those with non-cortical type SCI had similar vascular risk factors, laboratory data and MRI findings. Cortical type SCI patients had more severe initial neurologic manifestations(Both NIHSS score and Barthel index) than non-cortical type SCI. However, there was no specific difference in their degree of clinical improvement. Regarding MR angiography findings, cortical type SCI patients had MCA stenosis more often than non-cortical type SCI did whereas non-cortical type SCI patients showed heterogeneous MR angiography findings. Conclusion: SCI with similar shape and location may have different clinical manifestations(cortical or non-cortical) according to the underlying vascular lesions.Korean Journal of Stroke 2002;4(2):88~95

MZ세대의 퍼스널 트레이닝 센터 선택속성에 대한 IPA 분석 : 부산지역을 중심으로

정산,김태훈 한국사회체육학회 2023 한국사회체육학회지 Vol.- No.92

Purpose: The purpose of this study is to present a generation MZ infwlo strategy and a plan to establish and improve a new marketing strategy by analyzing the attributes of training centers recognized s important by generation MZ users, using the importance-performance analysis (IPA). Method: To achive this, 332 users of the generation MZ who utilized apersonal training center in the Busan area were selected as subjects, and a questionnaire was sued to collect data. Data processing involved the use of SPSS Window Version 28.0, and involved reliaiblity analysis, exploratory factor analysis , frequency analysis, paired-sample t-test, and IPA analysis. Results: The study revealed that the following attributes were important for generation MZ users: leader’ s personality and communication style, sincere guidance from the leader, long-term discounts and event benefits, home accessibility, and provision of free sportswear and towels (quadrant 1). Additionally, cleanliness of changing rooms and shower rooms and internal temperautre and ventilation facilities were also found to be important (quadrant 2). Safety facility and emergency supplies, parking lot availability, onetime experience cost, one-month use cost, one-time PT cost, and vending machine availability were also important (quadrant 3). Lastly, the appearance, career and academic background of the leader, and convenience of public transportation were iden Conclusion: Based on these results, it can be concluded that generation MZ users value facility cleanliness and internal ventilation when selecting a personal trainign center. Therefore, it is recommended tha t feedback from the MZ generation be utilized to improve the hygiene and cleanliness of facilities, by reflecting the characteristics of this generation who are familiar whit social media and frequently share their e-x periences. Additionally, an indoor space can be provided for MZ generation’s social media activities, as this can lead to effective marketing through this group.

기술시대 지역정신을 존중하는 현대경관설계 : 북경사계스키장 경관계획 사례

丁山,이기철,박승범,남정칠,김승환,강영조 東亞大學校 建設技術硏究所 2007 硏究論文集 Vol.30 No.2

The Four-Season ski resort which is prepared for 2008 Beijing Olympic project is the biggest indoor ski-dome. The fundamental concept for landscape design is to harmonize the development of Beijing city via the construction of modern building, the culture of China and Olympic spirit. Thus, the concept is evolved from the satisfaction of public, the realization of ecology and the site-of-art technique. The project requires the value of regional spirit when carrying out the planning of landscape. Thus, the starting point of design is evolved from the respect for nature, humanism, culture, sustainable development of city and ecosystem.