The Impact of Esophageal Refl ux-Induced Symptoms on Quality of Life after Gastrectomy in Patients with Gastric Cancer

이민혜,김종원,김완식,김지현,윤영훈,박효진,최승호 대한위암학회 2014 Journal of gastric cancer Vol.14 No.1

Purpose: To evaluate the prevalence of esophageal reflux-induced symptoms after gastrectomy owing to gastric cancer and assess therelationship between esophageal reflux-induced symptoms and quality of life. Materials and Methods: From January 2012 to May 2012, 332 patients were enrolled in this cross-sectional study. The patients had a history of curative resection for gastric cancer at least 6 months previously without recurrence, other malignancy, or ongoing chemotherapy. Esophageal reflux-induced symptoms were evaluated with the GerdQ questionnaire. The quality of life was evaluated with the European Organization for Research and Treatment QLQ-C30 and STO22 questionnaires. Results: Of the 332 patients, 275 had undergone subtotal gastrectomy and 57 had undergone total gastrectomy. The number of GerdQ(+) patients was 58 (21.1%) after subtotal gastrectomy, and 7 (12.3%) after total gastrectomy (P=0.127). GerdQ(+) patients showed significantly worse scores compared to those for GerdQ(?) patients in nearly all functional and symptom QLQ-C30 scales, with the difference in the mean score of global health status/quality of life and diarrhea symptoms being higher than in the minimal importantdifference. Additionally, in the QLQ STO22, GerdQ(+) patients had significantly worse scores in every symptom scale. The GerdQ score was negatively correlated with the global quality of life score (r=-0.170, P=0.002). Conclusions: Esophageal reflux-induced symptoms may develop at a similar rate or more frequently after subtotal gastrectomy comparedto that after total gastrectomy, and decrease quality of life in gastric cancer patients. To improve quality of life after gastrectomy, newstrategies are required to prevent or reduce esophageal reflux.

HMD 착용 중의 충돌 사고 방지를 위한 알리미 모듈 설계

이민혜,조승표,신성윤,이홍로,Lee, Min-Hye,Cho, Seung-Pyo,Shin, Seung-Yoon,Lee, Hongro 한국정보통신학회 2022 한국정보통신학회논문지 Vol.26 No.11

Virtual reality content provides users with a high sense of immersion by using HMD devices. However, while wearing the HMD device, it is difficult to determine the user's location or distance from obstacles, resulting in injuries due to physical collisions. In this paper, we propose a reminder module to prevent accidents by notifying the risk of collision with obstacles while wearing the HMD device. The proposed module receives the user's state from the acceleration and gyro sensor and determines the motion that is likely to cause a collision. If there is an obstacle in the expected collision range, a buzzer sounds to the wearer. As a result of the experiment, the accuracy of obstacle detection in the state of wearing the HMD was 86.6% in the 1st stage and 83.3% in the 2nd stage, confirming the performance of the accident prevention reminder.

심신의학 기전에 관한 세포생리 분석 연구

이민혜,이영좌,선민아,박은주,장성철,정동명 원광대학교 인체과학연구소 2010 원광인체과학회지 Vol.11 No.1

의식과 신체의 상관성에 관한 많은 연구결과는 동양철학의 심신일여(心身一如)에서부터 일체유심조(一切唯心造)까지 정립되어 있고, 현대의학의 임상의학과 분자생물학에서 그 임상효과가 입증되어 정신신경면역학을 태동시키고 심신의학의 기반이 되고 있다. 그러나 심신의 상관성과 상호작용에 대한 작용기전의 규명과 그 연구결과를 응용하는 심신과학은 아직도 보완통합의학에서 차지하는 영역이 극히 적은 편이다. 이에 따라 본 논문에서는 심신 작용의 핵심이 되고 있는 두뇌와 자율신경계의 작용기전, 감정과 신념에 대한 자율신경계 상호작용, 언어와 습관에 의한 두뇌작용, 생리적 스트레스와 일상적 스트레스에 대한 세포 작용, 체성신경계와 두뇌의 정보처리과정과 인식작용, 자율신경계와 체성신경계의 상호작용을 분석하고 플라시보와 최면요법, 명상과 참선, 트랜스퍼스널과 각종 심신치유와 수련의 효율성을 높힐 수 있는 방법으로서 적용 가능한 심신상관성의 특성에 대하여 고찰하였다.

생활과 함께하는 커피에 관해

이민혜,Lee, Min-Hye 한국특허정보원 2004 Patent 21 Vol.57 No.-

조선족 이민자의 문화적응, 사회적 관계망과 건강 관련 삶의 질의 관계

이민혜,이현경,김수,장연수 한국지역사회간호학회 2013 지역사회간호학회지 Vol.24 No.4

Purpose: The purpose of this study is to identify relationships between acculturation, social network, and health-relatedquality of life (HRQOL) among Korean-Chinese immigrants. Methods: A cross-sectional descriptive studywas conducted with 147 Korean-Chinese immigrants who were residing more than 1 year in Korea. Physical andmental dimensions of HRQOL were assessed by Short Form-12 Health Survey that consisted of a physical componentsummary (PCS) and a mental component summary (MCS). Data were analyzed with Pearson’s correlationand multiple regression. Results: The mean PCS score was 41.14±10.72 and the mean MCS score was49.09±11.31 (possible range 10-70). Depression (β=-6.43) and Social network frequency (β=2.44) explained28.4% of the variance in PCS while depression (β=-11.54) and visiting clinic/hospital (β=-4.00) explained 34.3%of the variance in MCS. Acculturation was not significantly associated with HRQOL. Conclusion: This study confirmedthat the social network frequency influences HRQOL among Korean-Chinese Immigrants. The findingssuggest that social network analysis should be considered in the process of developing health intervention strategiesfor Korean-Chinese immigrants.

Study on heat shield of PEDOT:PSS composite with various additives

이민혜,이경민,이차은,이상국,정승용,신교직,김명준,최경호 한국고분자학회 2011 한국고분자학회 학술대회 연구논문 초록집 Vol.2011 No.1

독거노인 위험감지형 모바일 맥박센서 개발

이민혜,정동명 원광대학교 인체과학연구소 2011 원광인체과학회지 Vol.12 No.1

본 논문은 독거노인 또는 부정맥 환자의 24시간 응급감시 모니터링을 위해 광소자를 이용한 독거노인 위험감지형 맥박센서를 설계했다. 투과형의 광소자를 사용한 맥박 측정 센서는 상용 기술이지만, 이것은 의료 기관에서 환자나 환자 진료 모니터링을 위한 일회성 측정 방법이다. 때문에 일상생활에서 무구속의 지속적인 측정이 가능한 센서 개발이 필요하며, 또한 내구성과 편의성, 유동성에 대한 신뢰성과 안정성을 유지해야한다. 이러한 조건에서 우리는 손목시계 타입의 독거노인 위험감지형 맥박 센서를 설계하고, 실험 결과에서 그 가능성을 확인했다.

다변량 시계열 자료를 이용한 부정맥 예측

이민혜,노호석 한국통계학회 2019 응용통계연구 Vol.32 No.5

Studies on predicting arrhythmia using machine learning have been actively conducted with increasing number of arrhythmia patients. Existing studies have predicted arrhythmia based on multivariate data of feature variables extracted from RR interval data at a specific time point. In this study, we consider that the pattern of the heart state changes with time can be important information for the arrhythmia prediction. Therefore, we investigate the usefulness of predicting the arrhythmia with multivariate time series data obtained by extracting and accumulating the multivariate vectors of the feature variables at various time points. When considering 1-nearest neighbor classification method and its ensemble for comparison, it is confirmed that the multivariate time series data based method can have better classification performance than the multivariate data based method if we select an appropriate time series distance function. 최근에 부정맥 환자가 증가하면서 머신러닝을 이용한 부정맥을 예측하는 연구가 활발하게 진행되고 있다. 기존의 많은 연구들은 특정한 시점의 RR 간격 데이터에서 추출한 특징변수 다변량 데이터에 기반하여 부정맥을 예측하였다. 본 연구에서는 심장 상태가 시간에 따라 변해가는 패턴도 부정맥 예측에 중요한 정보가 될 수 있다고 생각하여 일정한 시간 간격을 두고 특징변수의 다변량 벡터를 추출하여 쌓음으써 얻어지는 다변량 시계열 데이터로 부정맥을 예측하는 것의 유용성에 대해 살펴보았다. 1-Nearest Neighbor 방법과 그것을 앙상블(ensemble)한 learner를 중심으로 비교했을 경우 시계열의 특징을 고려한 적절한 시계열 거리함수를 선택하여 시계열 정보를 활용한 다변량 시계열 데이터 기반 방법의 분류 성능이 더 좋게 나오는 것을 확인하였다.

2000년 이후 갑상선 기능저하증에 대한 국내 한의학 실험연구 체계적 고찰

이민혜,최유경,Lee, Min-hye,Choi, You-kyung 대한한방내과학회 2015 大韓韓方內科學會誌 Vol.36 No.4

Objectives The purpose of this study was to investigate the experimental studies which was performed by single or complex herbal medicines on hypothyroidism.Methods I searched the domestic experimental studies about single or complex herbal medicines’ effects on hypothyroidism that published since 2000 on 4 Korean databases by keywords, ‘thyroid gland’, ‘hypofunction’, ‘hypothyroidism’.Results 11 single herbal medicines and 9 complex herbal medicines in 20 experimental studies have reported their effectiveness and safetiness in PTU-induced hypothyroidism rats by evaluating the changes of several biochemical and hematological indexes.Conclusions In order to make new and more effective medicines on hypothyroidism, there should be further studies by using combinations of herbal medicines and the differences of their mechanisms.

Synthesis and Characterization of Alkyl - substituted Thienylenevinylene based Conjugated Copolymer for Organic Solar Cells

이민혜,김주환,여준석,김동유 한국고분자학회 2012 한국고분자학회 학술대회 연구논문 초록집 Vol.2012 No.4