A-14 : Preparation and charaterization of chitosan-based superporous semi-IPN hydrogels

박효진,김덕준 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.2

The purpose of this study was to develop chitosan-based porous semi-interpenetrating polymer network(semi-IPN) for gastric retention device. Chitosan and glycol chitosan hydrogels with numerous pores were prepared, and their swelling behaviors in acidic solution were studied. And, to improve mechanical strength of hydrogels, PEO and PVA were used in IPN synthesis with glycol chitosan. Swelling studies were performed in different pH solution at 37°C. Morphology and pore size of hydrogels were confirmed by scanning electron microscopy(SEM). Mechanical strengths were determined by UTM.

한국 봄철 PM<SUB>10</SUB> 변동 패턴과 대기변수의 관계

박효진,위지은,문병권 한국기상학회 2016 한국기상학회 학술대회 논문집 Vol.2016 No.10

만성부비동염으로 비내시경 수술을 시행 받은 환자에서MRSA 감염에 대한 임상적 분석 및 외래에서의적절한 항생제 치료법

박효진,오소정,진재원,노영수 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.4

Background and Objectives:Methicillin resistant staphylococcus aureus (MRSA) prevalence has increased over the world during past several decades and now it has become a world wide problem. It is especially more serious in domestic situations but unfortunately, until this time, there is no report about MRSA infection treatment after endoscopic sinus surgery (ESS). The objective of our study is to evaluate clinical feature of MRSA infection and to find out what kinds of treatment is the best way to control of the MRSA infection after ESS. Subjects and Method:The medical records of 58 patients who had the evidence tively reviewed. Samples were obtained by sinus endoscopy in the office base. Results:Those of MRSA infected only cases were 26 cases. Co-infected cases with another microorganism were 32 cases. Forty-three cases were treated with oral rifampin alone and 11 cases were treated by a combination with oral quinolone or trimethoprim-sulfimethoxazole. Four cases failed to be treated with oral antibiotic therapy. Conclusion:Rifampin is the useful medication for the treatment of MRSA infected patients who had underwent ESS. Also, Rifampin is a cost effective medication compared with the glycopeptide antibiotics esp (Korean J Otolaryngol 2007 ;50 :314-8)

간호사의 임종간호 태도에 미치는 영향요인

박효진,강은희 한국중환자간호학회 2020 중환자간호학회지 Vol.13 No.1

Purpose : The purpose of this study was to identify the extent to which nurses’ death perceptions, death anxiety, and stress associated with terminal care affects their attitudes toward terminal care. Method : A total of 214 nurses were asked questions about characteristics, death perceptions, death anxiety, stress associated with end-of-life care, and terminal care attitudes, using structured questionnaires. The data were analyzed using descriptive analysis, t-test, ANOVA, Scheffé’s test, Pearson’s correlation coefficients, and stepwise multiple regression. Results : Factors influencing terminal care attitudes in participants were positive meaning associated with death, respect for life, final education, end-of-life nursing education experiences, stress associated with end-of-life care, death anxiety, and position. These factors explained 38.7% of variance in participants’ terminal care attitudes (F=20.18, p <.001). Conclusion : In order for nurses to have a positive attitude toward terminal care, it is necessary to raise positive awareness about death and respect for life, and it is necessary to develop various educational programs and strengthen their capacity through continuous education.

Correlation between Sestrin-2 and PERK Signaling in Matured Porcine Oocytes according to ER-stress during In Vitro Maturation

박효진,김인수,김진우,양슬기,김민지,구덕본 사단법인 한국동물생명공학회 2019 한국동물생명공학회지 Vol.34 No.3

Sestrin-2 (SESN2) as a stress-metabolic protein is known for its anti-oxidative effects as a downstream factor of PERK pathways in mammalian cells. However, the expression patterns of SESN2 in conjunction with the UPR signaling against to ER stress on porcine oocyte maturation in vitro, have not been reported. Therefore, we confirmed the expression pattern of SESN2 protein, for which to examine the relationship between PERK signaling and SESN2 in porcine oocyte during IVM. We investigated the SESN2 expression patterns using Western blot analysis in denuded oocytes (DOs), cumulus cells (CCs), and cumulus-oocyte complexes (COCs) at 22 and 44 h of IVM. As expected, the SESN2 protein level significantly increased (p < 0.01) in porcine COCs during 44 h of IVM. We investigated the meiotic maturation after applying ER stress inhibitor in various concentration (50, 100 and 200 μM) of tauroursodeoxycholic acid (TUDCA). We confirmed significant increase (p < 0.05) of meiotic maturation rate in TUDCA 200 μM treated COCs for 44 h of IVM. Finally, we confirmed the protein level of SESN2 and meiotic maturation via regulating ER-stress by only tunicamycin (Tm), only TUDCA, and Tm + TUDCA treatment in porcine COCs. As a result, treatment of the TUDCA following Tm pre-treatment reduced SESN2 protein level in porcine COCs. In addition, SESN2 protein level significantly reduced in only TUDCA treated porcine COCs. Our results suggest that the SESN2 expression is related to the stress mediator response to ER stress through the PERK signaling pathways in porcine oocyte maturation.

소 간에서 다이오드레이저를 이용한 간질성 광응고술

박효진 대한영상의학회 1999 대한영상의학회지 Vol.40 No.1

Purpose : To evaluate the extent of tissue coagulation during interstitial laser photocoagulation (ILP) innormal bovine liver, using a diode laser unit and various parameters, and to determine whether the procedure isapplicable to clinical practice.. Materials and Methods : Using an 18-gauge needle, experimental interstitiallaser photocoagulation (ILP) was carried out in normal bovine liver. On the basis of differing parameters, threegroups were established. For groupI, a single photofiber with laser power of 1, 3 and 5 watts and an exposuretime of 60, 180, 300, 420 or 600 seconds was used. For groups II and III, four needles were fixed at a distance of1cm and 1.5cm ; in each case a needle fixation device was used, as well as a laser distributor for simultaneouslaser exposure of photofibers. As a control, four photofibers were placed as for groupIII, but to compare groups IIand III, each photofiber was exposed to a laser of 3 watts 300 seconds, without using a laser distributor. Toevaluate the range of tissue coagulation, specimens were analyzed both with regard to cross-sectional grossfindings and histopathologically . Results : The largest diameter of thermal coagulation necrosis in GroupI was15$\times$15mm, and this was ball-shaped. Coalescence of coagulation between each photofiber was observed in GroupII,and this was up to 25 mm in diameter. In GroupIII and controls, coalescence was not found, though the extent oftissue coagulation increased with increasing wattage and exposure time. The extent of charring at the center ofcoagulation also increased with increasing wattage. Smoke bubbles emanating from the coagulation area wereobserved, and during ILP involving a single photofiber, increased from 3 watts, applied for 300 seconds.Conclusion : Using an 8-gauge needle and a diode laser ILP, we have shown that a range of tissue coagulationacutely ablates normal bovine liver. In selective cases, the procedure could be applied to clinical trials.

임상간호사의 임종간호수행 구조모형

박효진,이윤미,김민혜 한국중환자간호학회 2021 중환자간호학회지 Vol.14 No.1

Purpose : Based on Quint’s theory and the relevant literature, this study constructed a structural equation model for explaining and predicting end-of-life care performance in clinical nurses. Methods : A self-administered questionnaire was used to collect data from 265 nurses between September 1 and September 30, 2016. The data were analyzed using SPSS ver. 21 and AMOS ver. 21. Results : The goodness of fit of the modified model was found to be relatively satisfactory (χ2=114.82, Nomed χ2(χ2/df)=2.44, SRMR=.06, GFI=.94, AGFI=.89, CFI=.95, TLI=.91, RMSEA=.07). End-of-life care performance was affected by the attitudes toward nursing care of the dying, working unit, and death anxiety. The attitudes toward such care had the highest effect on end-of-life care performance. Conclusion : The results suggest that end-of-life care performance is directly and indirectly affected by attitudes toward nursing care of the dying, participation in end-of-life care education, working unit, death perception, and death anxiety. To improve clinical nurses’ end-of-life care performance, effective programs to promote death anxiety and attitudes toward nursing care of the dying need to be developed. In addition, hospital nursing organizations should attempt to produce concrete measures for death anxiety and terminal care attitudes in clinical nurses.

토지계획 정리사업에 관한 연구

박효진 단국대경영대학원 1988 經院論叢 Vol.8 No.-

대학생의 학업스트레스와 전공만족도의 관계 : 자기효능감과 사회적 지지의 영향요인

박효진,유은주,이화명 한국콘텐츠학회 2020 한국콘텐츠학회논문지 Vol.20 No.2

This study also examined the influence of academic stress on major satisfaction of college students and the influence of self-efficacy and social support. The subjects of this study were 320 students attending K university in B city. The 295 questionnaires were collected and 291 questionnaires were finally analyzed except for 4 questionnaires that were insufficient. Major satisfaction had a statistically significant negative correlation with academic stress, and major satisfaction had a statistically significant positive correlation with self-efficacy. Also, major satisfaction had a statistically significant positive correlation with social support. Finally, as a result of examining the effects of each factor, academic stress, self-efficacy, and social support had a significant effect on major satisfaction except for informational support in social support. In order to increase the satisfaction of college students, it is necessary to study the factors that can lower academic stress and develop the program accordingly. It is necessary to develop educational methods and programs that can increase self-efficacy and social support. This is considered to have a positive effect on the satisfaction of college students.

쓰레기 속의 삶과 노동 ―폐기물 관리의 변화와 난지도 매립지 주민들의 주거권

박효진 역사문제연구소 2024 역사비평 Vol.- No.149

급격한 도시화는 폐기물 발생량 증가로 인한 쓰레기 처리에 필요한 공간과 노동력을 요구한다. 난지도 매립지(1978-1993)는 서울시가 이러한 문제에 어떻게 대응했는지 보여준다. 난지도는 약 2천여 명의 비공식 노동자와 4천여 주민의 삶의 터전이자 생업의 공간이었다. 이 글은 1978-84년 난지도 주민들의 주거 현황, 특히 1980년대 중반 매립지 폐쇄가 논의되던 시기에 난지도 주민들의 주거권 요구와 조립식 주택 건설과정을 다룬다. 주민, 공무원, 자원봉사자 인터뷰, 청원서와 민원서류, 폐기물 정책 보고서, 항공 사진과 판잣집 지도를 바탕으로 주민들이 주거권을 인정받을 수 있었던 계기와, 1980년대 폐기물 관리 정책 변화 속에서 이들의 주거 상황이 어떻게 달라졌는지 분석한다. 1983년 11월 서울시가 매립공간 확보를 위해 주민들에게 자진 철거를 요구하자 이들은 철거 위협에 맞서 주거권을 주장했다. 주민들은 직접 설문 조사를 실시하고 판자촌 지도를 제작하여 자신들의 존재를 증명했다. 이러한 “국가처럼 보기” 전략을 통해 주민들은 임시정착지로 조립식 주택을 얻어냈다. 그러나 기계식 물질 회수 시설이 실패하고 신규 위생 매립지 선정이 지연되면서 서울시는 1993년까지 난지도 매립지에 의존할 수밖에 없었고, 주민들은 조립식 주택에 10년 이상 거주하며 폐품 수집을 이어가게 되었다. 국가는 장기적인 노동력 재생산을 염두에 두고 주민들에게 임시정착지를 제공한 것은 아니었지만, 이들의 비공식 노동을 암묵적으로 허용함으로써 매립지 운영 비용을 최소화했다. 그러나 주민들의 노동을 공식화하거나 그 기여를 인정하지 않음으로써 이들의 주변화와 비가시성을 지속시켰다. 난지도 주민들의 사례는 도시 하층민의 삶과 노동이 단순히 도시화 문제에 국한되지 않고 폐기물 정책이나 환경 관리의 발전 등 더 큰 구조적 변화와 연결되어 있음을 보여준다. Accelerated urbanization confronts cities with increasing waste volume, labor demands, and space constraints. The Nanjido landfill (1978~1993) illustrates Seoul’s response to these challenges. Nanjido served as the city’s landfill, a workplace of approximately 2,000 informal waste pickers, and home to 4,000 residents. This article examines the housing demands of Nanjido dwellers in 1983~1984, analyzing the reasons why residents could obtain their housing rights and the subsequent changes in their living conditions as a result of the shifting waste management system. In November 1983, nearing the landfill’s closure, the city demanded waste pickers to demolish their shacks. They conducted a demographic survey and produced a hand-drawn shanty town map to prove their presence and demand their rights to housing―a “seeing like a state” strategy that resulted in the provisional resettlement in a prefabricated housing complex. Nevertheless, due to the failure of the material recovery facility and the delay in selecting a new landfill site, Nanjido residents were compelled to live in prefabricated housing for more than a decade and work as landfill waste pickers. The provisional housing did not necessarily consider containing the long-term reproduction of labor. Yet, the state implicitly permittedthe informal labor of waste pickers and benefitted fromit withoutformalizing their labor or acknowledging their contributions, thereby perpetuating their marginalization and invisibility. The Nanjido case demonstrates that the lives and labor of the urban underclass are not only shaped by issues of urbanization but are also by broader structural changes, such as advancements in waste management policy or the emergenceof environmental management.