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      • KCI등재

        Face mask를 이용한 유치열기 골격성 반대교합의 치료

        서주희,이광희,김대업,이지영,Seo, Ju-Hee,Lee, Kwang-Hee,Kim, Dae-Eop,Lee, Ji-Young 대한소아치과학회 2002 大韓小兒齒科學會誌 Vol.29 No.1

        III급 부정교합은 서양인에서 약 5%의 발생빈도를 보이며, 일본인과 한국인에서 교정환자중 50%정도로 증가하는 추세이다. 이런 III급 부정교합자의 63%가량이 상악골의 열성장 또는 상악골의 열성장과 하악골의 과성장에 의한 것이라고 알려져 있다. 일반적으로 환자의 나이가 많을수록 악정형력보다는 치열에서의 변화량이 크므로 치료는 조기에 시행하는 것이 바람직하다고 하였다. 조기치료시 성장조절, 환자의 협조도, 치료의 관리와 같은 결정요소들을 잘 판단하여 시행함으로써 상악골의 더 많은 전방이동이 가능하며 정상 성장을 도모하고 교합관계가 증진되며 안모의 개선으로 인해 정상적인 사회 심리적 발육이 이루어질 수 있다. 본 증례는 반대교합을 주소로 원광의료원 치과병원 소아치과에 내원한 유치열기 환아에게 facemask를 이용한 조기 치료로 양호한 결과를 얻었기에 보고하는 바이다. The prevalence of Class III malocclusion is approximately 5% in the Caucasian population, rising to as mush as 50% in the Japanese and Korean population. Recent studies have suggested than 63% of this malocclusion display maxillary retrusion. If left untreated, the malocclusion tends to worsen. Consequently, early treatment is commonly indicated to obtain a more normal jaw relationship. This report is 2 cases treated patients who diagnosed as skelectal Class III malocclusion due to deficient maxilla using facemask.

      • 오염된 유치 상아질에 대한 자가 부식 프라이머의 결합강도에 관한 연구

        서주희,이광희 원광대학교 치의학연구소 2002 圓光齒醫學 Vol.11 No.1

        Objective: The purpose of this study was to determine and compare the shear bond strength of two self-etching primer systems to primary teeth contaminated with saliva and blood. Materials and Methods: Clearf l SE Bond and AQ Bond were evaluated. One hundred specimens were made by seventy-five deciduous teeth(fifty anterior and twenty-five posterior teeth) and divided randomly into ten groups. Small flat dentinal surfaces were prepared by grinding the buccal, lingual and labial areas. Specific surface treatments were applied to each group: (1)a self-etching primer application(control group), (2)saliva contamination followed by primer(Group Ⅰ), (3)primer curing followed by saliva contamination (Group Ⅱ), (4)blood contamination followed by primer(Group Ⅲ), (5)primer curing followed by blood contamination(Group Ⅳ). After bonding of composite resin(Z100, 3M, USA) to contaminated sample surfaces and thermocycling(1,000 cycles), shear bond strengths were measured using Universal Testing Machine(Zwick Z020, Zwick Co., Germany). Results: The results were as follows; 1. Group Ⅰ showed lower shear bond strength than control group but no statistically significant difference was found(P>0.05). 2. Group Ⅱ and blood contamination group(Group Ⅲ & Ⅳ) showed significantly lower shear bond strength than control group(P<0.01). 3. The shear bond strength of Clearfil SE Bond was significantly higher than that of AQ Bond(P<0.05).

      • KCI등재

        국내 3-7세 어린이의 혈중 납, 수은, 카드뮴 농도와 관련요인

        서주희,김병권,김유미,김록범,정진용,홍영습,Seo, Ju-Hee,Kim, Byoung-Gwon,Kim, Yu-Mi,Kim, Rock-Bum,Chung, Jin-Yong,Hong, Young-Seoub 한국환경보건학회 2014 한국환경보건학회지 Vol.40 No.4

        Objectives: Children are more susceptible to heavy metal toxicity than adults. The purpose of this study was to evaluate heavy metal concentrations in the blood of Korean preschoolers and investigate the association between metals in blood and related factors. Methods: A total of 512 subjects from 36 to 83 months of age were sampled. A questionnaire survey was performed and the levels of lead, mercury and cadmium were measured in the blood samples of all subjects. Their parents were interviewed in order to obtain information on basic characteristics, dietary patterns, socio-economic factors, and indoor/outdoor environment of the preschoolers. Multiple linear regression was used to analyze the association between the above factors and lead, mercury or cadmium concentrations. Results: The geometric mean concentrations of lead, mercury and cadmium in the blood were $1.45{\pm}1.58{\mu}g/dL$, $2.14{\pm}1.74{\mu}g/dL$ and $0.23{\pm}1.91{\mu}g/dL$, respectively. Results from multiple linear regression analysis showed that blood lead levels were associated with birth weight and paternal smoking status. Daily mercury intake from food and maternal education were also shown to influence mercury concentrations in blood. Also, blood cadmium concentrations were associated with maternal age and having a bus garage near the place of residence. Conclusion: This study suggests that smoking status, dietary patterns and the environmental status near the residence should be considered as important factors for preventable sources of heavy metal exposure in preschoolers.

      • KCI등재후보

        신증후군 환자에서 스테로이드 충격요법과 경구용 면역억제제 치료 중 발생한 가역성 후백질뇌병증 1례

        서주희,신정욱,김지홍,윤춘식,Seo Joo Hee,Shin Jung Wook,Kim Ji Hong,Yoon Choon Sik 대한소아신장학회 2005 Childhood kidney diseases Vol.9 No.2

        저자들은 정맥 주사용 스테로이드 충격요법과 경구 cyclophosphamide 치료를 받던 신증후군 환아에서 가역성 후백질뇌병증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. The syndrome of reversible posterior leukoencephalopathy syndrome(RPLS) is characterized clinically by acute neurologic signs such as headache, vomiting, confusion, seizures, and visual abnormalities. Radiologically, abnormalities consistent with reversible white matter edema in the occipital and parietal lobes are characteristic. RPLS has often been associated with various systemic disorders, such as hypertensive encefhalopathy, eclampsia, and the use of intravenous or intrathecal immunosuppressive drugs. We report a case of RPLS that occurred after intravenous steroid pulse therapy and treatment with oral cyclophosphamide in a child with nephrotic syndrome, and we emphasize the importance of early recognition of RPLS in the treatment of nephrotic syndrome and appropriate management tn prevent Permanent neurologic disability. (J Korean Soc Pediatr Nephrol 2005;9:245-250)

      • KCI등재

        느릅나무 초임계 추출물의 항균, 항산화 및 항염증 활성

        서주희,이용조,조영익,고정윤,문명재,박광현,최선은 한국융합학회 2018 한국융합학회논문지 Vol.9 No.8

        천연물 유래 난치성 피부질환 기능성 소재를 탐색하기 위해 느릅나무 가지를 초임계 유체 기술을 활용하여 추출을 수행하였고, 확보된 느릅나무 초임계 추출물을 수종의 피부상재균에 대하여 항균력 실험을 실시하였고, 모든 균종에 대해서 항균력이 확인이 되었으며, ABTS 라디컬 소거능과 NO 소거능 실험을 통해서 느릅나무 초임계 추출물의 항산화 활성과 항염증 활성의 우수한 활성이 확인이 되어서 산화적 스트레스 질환과 염증성 피부질환에 대해서 예방 및 치료 보완 기능성 소재로 개발이 가능성이 높다는 것을 알 수 있었다. 결론적으로 느릅나무 초임계 추출물은 피부상재균에 대한 항균활성, 라디컬 소거능에 의한 항산화 활성, 과 생성된 NO 소거능에 의한 항염증활성이 각각 확인이 되었다. 이 상의 결과로 느릅나무 초임계 추출물은 항균효능, 항산화효능, 항염증 효능을 갖는 기능성 원료로서의 가능성을 확인할 수 있었고, 향후 만성 염증 성 피부면역 질환 개선 및 치료 보조제 관련 의약품 또는 기능성 향장품 개발을 위한 기초 연구 자료가 될 것으로 사료된다. The Ulmus davidiana have been used in traditional oriental medicine as remedies for inflammation, ulcers, cancers, bacterial infections and scabies. In this study, the anti-fungal, anti-oxidant, and anti-inflammatory activitiesof a supercritical extract of U. davidiana were investigated in vitro. To explore the anti-oxidant and anti-inflammatory characteristics of the supercritical extract, ABTS radical scavenging activity, and the inhibition of nitric oxide production in LPS-stimulated RAW 264.7 cells were examined, respectively. In addition, the anti-fungal activities of the extract were assessed. The results showed a concentration-dependent increase in ABTS radical scavenging activity. Cells stimulated with LPS produced more nitric oxide than normal control cells; however, cells treated with the supercritical fluid extract decreased this production in a concentration-dependent manner. Finally, the supercritical fluid extracts showed significant anti-fungal activity. These results suggest that extracts of the U. davidiana might be used to develop potent anti-fungal, anti-oxidant, and anti-inflammatory agents, and may be useful as ingredients for related new functional cosmetic materials.

      • KCI등재

        Predictors of Refractory Ascites Development in Patients with Hepatitis B Virus-Related Cirrhosis Hospitalized to Control Ascitic Decompensation

        서주희,김승업,박준용,김도영,한광협,전재윤,안상훈 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.1

        Purpose: Refractory ascites (RA) is closely related to a high morbidity and mortality. In this study, we investigated predictors of RA development in patients with hepatitis B virus (HBV)-related cirrhosis who were hospitalized to control ascitic decompensation,and determined predictors for survival in patients who experienced RA. Materials and Methods: We analyzed 199 consecutive patients with HBV-related cirrhosis who were hospitalized to control ascitic decompensation between January 1996 and December 2008. Results: Multivariate analyses showed that only serum potassium at admission predicted RA development independently [p=0.013; hazard ratio (HR), 2.800; 95% confidence interval (CI), 1.166-6.722]. During the follow-up period, 16 (8.0%) patients experienced RA within 4.2 (range, 1.0-39.2) months after admission for controlling ascitic decompensation, and they survived a median of 8.7 (range, 3.9-51.3) months. Child-Pugh class and RA type were identified as independent prognostic factors affecting the survival in patients with RA (p=0.045; HR, 8.079; 95% CI, 1.231-67.984 and p=0.013; HR, 14.510; 95% CI, 1.771-118.874, respectively). Conclusion: Serum potassium was an independent predictor of RA development in patients with HBV-related cirrhosis who were hospitalized to control ascitic decompensation. After RA development, Child-Pugh class and RA type were independent predictors for survival.

      • KCI등재

        An 18-year experience of tracheoesophageal fistula and esophageal atresia

        서주희,김도연,김대연,김성철,김인구,김기수,윤종현,피수영,김애란 대한소아청소년과학회 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.6

        Purpose: To determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit. Methods: A retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neonatal intensive care unit between 1990 and 2007. Results: The rate of prenatal diagnosis was 12%. The average gestational age and birth weight were 37+2 weeks and 2.5±0.7 kg,respectively. Thirty-one infants were born prematurely (32%). Type C was the most common. The mean gap between the proximal and distal esophagus was 2 cm. Esophago-esophagostomy was performed in 72 patients at a mean age of 4 days after birth; gastrostomy or duodenostomy were performed in 8 patients. Forty patients exhibited vertebral, anorectal, cardiac, tracheoesophageal, renal,limb (VACTERL) association with at least 2 combined anomalies,and cardiac anomaly was the most common. The most common post-operative complications were esophageal stricture followed by gastroesophageal reflux. Balloon dilatation was performed for 1.3 times in 26 patients at a mean age of 3 months. The mortality and morbidity rates were 24% and 67%, respectively, and the most common cause of death was sepsis. The weight of approximately 40% patients was below the 10th percentile at 2 years of age. Conclusion: Mortality and morbidity rates of patients with TEF and EA are high as compared to those of infants with other neonatal surgical diseases. Further efforts must be taken to reduce mortality and morbidity and improve growth retardation.

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