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      • KCI등재

        Friedrich Holderlin 의 송가 「Dem Sonnengott」 연구

        박준규 한국독어독문학회 1982 獨逸文學 Vol.28 No.1

        Dicse Abhandlung setzt sick die Aufgabe, eine dcr Kurz-Oden der Frankfurter Zeit, Dem Sonnengott and damn die Umarbeitung der Ode zur Kurz-Ode Sonnenuntergang zu erhellen. H&lderlin hat zahlreiche Oden der Frankfurter Zeit (1796-1798) nach 1800 weiterentwickelt, indem er die meist ein- and zweistrophigen Gedichte zu grolben Gesange ausbaute. Die Kontinuitat von Htflderlins Odendichtung zeugt von seiner Treue zur Odenform. Nun besteht aber die Umarbeitung der Ode wesentlich in erner Kurzung. Das Gesetz dieser Ode ist die 1'berganglichkeit. Die l)berganglichkeit der alkaischen Strophe trill in dicier Ode nicht nur durch den Wechsel in der Darstellungsweis hervor, sondern sie tvird in der ersten and zweiten Strophe lurch den Tempusweclael auch noch syntaldisch verdeutlicht. Und diese Ubcrbanglichkeit verkniipft rich eng mil dcm aus der Identitatsphilosophie bekannten Dreischnitt. Die hicr zutage trEacnde Grundstruktur der prophetischen Dichtung findet ihr Vorbild in dcm mythisch gedeuteten Verhalthnis von Sonne and Erde, wo ebenfalls eine einstige Vereinigung and nachherige Trennung zu einer neuen, wechselvollcn Annaherung fiihrt. Die mythische Phantasie ist fiir II&lderlin kein blol3es Schmuckstiick, das wir nachtraglich dem Bill der Wirklchkeit hinzufugen, sondern sie ist eines der notwcndigen Organe fiir die Erfassung der Wirklichkeit selbst. In ihm fndet er Welt and Leben erst wahrhaft erschlossen and gedeutet. In der umgearbeiteten Ode wird aber nicht mehr mythologische Vorstellungen aufgerufen. Nun verzichtet der Dichter auf die Mythologisierung. Er kann an Stelle der seelenlos gewordenen Giitternamen Sonnenuntergang sagen. Dadurch wird aber auch die Gtitterverehrung zur Naturverehrung. Htilderlin hat sich fur die Verehrung der Naturmachte entschieden.

      • KCI등재
      • KCI등재

        Effect of Long-Term Application of Ammonium Sulfate, Urea, Composts, and Calcium Silicate on Macroelements and Rice Yields in Paddy Soil

        박준규,오왕근,김원출,Park, Jun-Kyu,Oh, Wang-Keun,Kim, Weon-Chul 한국토양비료학회 1990 한국토양비료학회지 Vol.23 No.4

        논 토양(土壤)에 황산(黃酸)암모늄, 요소(尿素), 퇴비(堆肥) 및 규산질비료(珪酸質肥料)의 장기연용(長期連用)이 주요(主要) 토양양분(土壤養分)의 행동(行動)과 벼의 수량(收量)에 미치는 영향에 대한 시험결과(試驗結果)를 요약(要約)하면 다음과 같다. 1. 토양(土壤)의 pH는 요소단용(尿素單用)에 비하여 황산(黃酸)암모늄 단용(單用)이 시험실시년한(試驗實施年限)이 경과(經過)함에 따라 더욱 낮아졌으며 요소(尿素) 및 황산(黃酸)암모늄에 퇴비(堆肥), 규산질(珪酸質) 비료병용(肥料倂用)은 요소(尿素), 황산(黃酸)암모늄단용(單用)보다 pH가 현저히 높은 경향을 보였다. 2. 토양유기물함량(土壤有機物含量)은 황산(黃酸)암모늄, 요소단용(尿素單用) 및 3요소구(要素區)보다 여기에 퇴비(堆肥) 및 규산질비료병용(珪酸質肥料倂用)이 현저히 증가(增加)하였다. 3. 토양중(土壤中)의 N, $P_2O_5$, Ca, Mg, $SiO_2$함량(含量)은 3요소(要素)에 비하여 3요소(要素)에 퇴비병용토양(堆肥倂用土壤)에서 현저히 증가(增加)하였으나 K는 오히려 낮은 경향을 보였는데 이는 벼의 생육증가(生育增加)로 K의 흡수량(吸收量) 증가(增加)와 퇴비시용(堆肥施用)으로 인한 토양(土壤)의 투수성(透水性) 개량(改良)으로 K의 용탈(溶脫)을 촉진(促進)시킨 것으로 본다. 4. 황산(黃酸)암모늄과 퇴비(堆肥) 및 규산질비료병용(珪酸質肥料倂用)에 비하여 요소(尿素)와 퇴비(堆肥) 및 규산질비료병용토양(珪酸質肥料倂用土壤)에서 치환성(置換性) Ca, Mg의 증가(增加)는 황산(黃酸)암모늄 시용(施用)이 $CaSO_4$ 또는 $MgSO_4$로 용탈(溶脫)을 촉진(促進)시킨 것으로 본다. 5. 토양(土壤)중(中) 질소(窒素)의 함량(含量)은 퇴비시용(堆肥施用)으로 증가(增加)되나 규산질비료(珪酸質肥料)의 병용(倂用)은 질소(窒素)의 함량(含量)을 현저히 감소(減少)시켰다. 이는 규산질비료병용(珪酸質肥料倂用)으로 토양질소(土壤窒素)의 무기화(無機化)를 촉진(促進)시킨 결과(結果)라고 생각된다. 6. 벼의 수량(收量)은 황산(黃酸)암모늄 및 요소단용시(尿素單用時)에는 수량(收量)의 차이를 보이지 않았으나 퇴비(堆肥), 규산질비료(珪酸質肥料) 병용시(倂用時)에는 황산(黃酸)암모늄에서 증수(增收)경향을 보였는데 이는 황산(黃酸)암모늄의 부성분(副成分)인 황(黃)의 효과라고 본다. A study has been conducted since 1954 to elucidate the effects of longterm application of ammonium sulfate (AS), urea, compost, and calcium silicate(CS) fertilizers on major soil nutrients and rice yields in wetland soil. The soil pH in the AS plot become lower than that in the urea plot but had little influence on rice yield. Continuous application of AS and urea with compost and CS raised the soil pH compared with single applications of AS or urea. Soil organic matter content increased yearly in plot with no fertilizer and in those with AS and urea, and increased considerably in plots with compost and CS. Application of compost and CS promoted rice top growth as well as root growth, resulting in increased dry matter. Soil contents of N, $P_2O_5$, Ca, Mg, and $SiO_2$ in the NPK with composts plot increased considerably compared with the NPK plot; however. the exchangeable K content was rather low. Rice growth increased with compost application. which enhanced K uptake, and the coarse texture promoted K leaching. With compost and CS addition, con tents of exchangeable Ca and Mg in the AS plot decreased considerably more than in the urea plot. Probably this was the result of higher Ca and Mg precipitation by sulfate in the AS plot. The re are no significant differences in rice yield between AS and urea plots. With compost and CS treatments, rice yields increased in the AS plot compared with the urea plot. The increase in yield is considered to be the effect of S. which is a constituent of AS.

      • KCI등재

        Poly-L-lactide Polymer-Based Triple Drug-Eluting Stent with Abciximab, Alpha-Lipoic Acid and Sirolimus in Porcine Coronary Restenosis Model

        박준규,김성수,김현국,나재운,김한별,배인호,박대성,심재원,이민영,김중선,구본상,정강진,진영배,김선욱,이상래,나주영,심두선,홍영준,임경섭,정명호 한국고분자학회 2020 Macromolecular Research Vol.28 No.1

        This study evaluated the effect of a novel triple drug-eluting stent containing antithrombotic abciximab, antioxidative alpha-lipoic acid (ALA), and antiproliferative sirolimus in a porcine model. The coronary arteries of pigs were randomized into three groups: triple drug-eluting stent (TES; n=10), sirolimus-eluting stent (SES; n=10), and bare metal stent (BMS; n=10). At 28 days after stent implantation, a histopathologic analysis was performed. There were no significant differences in the injury score. There were significant differences in the neointimal area (2.3±0.6 mm2 in TES vs. 2.5±0.88 mm2 in SES vs. 3.3±0.58 mm2 in BMS, p<0.0001), percent area of stenosis (37.1±9.26% in TES vs. 46.1±15.9% in SES vs. 66.2±10.12% in BMS, p<0.0001), inflammation score (1.0 [range, 0.0-1.0] in TES vs. 1.5 [range, 1.0-2.0] in SES vs. 1.0 [range, 1.0-2.0] in BMS, p<0.05), and fibrin score (2.0 [range, 1.0-2.0] in TES vs. 2.0 [range, 1.0-2.5] in SES vs. 0.0 [range, 0.0-1.0] in BMS, p<0.0001) among the three groups. The occlusion rates using micro-computed tomography showed similar restenosis rates based on histologic analysis (35.4±8.39% in TES vs. 43.4±10.12% in SES vs. 71.4±4.38% in BMS, p<0.0001). TES demonstrated an inhibitory effect on the smooth muscle cells compared to the other stents. It also suppressed inflammation in the stented lesion compared to SES as evidenced by the inflammation score.

      • KCI등재

        Bile Acid Conjugated Chitosan Oligosaccharide Nanoparticles for Paclitaxel Carrier

        박준규,나재운,김태훈,남정표,박성철,박영훈,장미경 한국고분자학회 2014 Macromolecular Research Vol.22 No.3

        To develop a paclitaxel carrier based on chitosan, chitosan oligosaccharide (COS) was chemically modifiedwith bile acid (deoxycholic acid and lithocholic acid) as a hydrophobic group. Paclitaxel was loaded in bile acid conjugatedchitosan oligosaccharide (CBs) nanoparticles by a dialysis method. We confirmed that the paclitaxel-loadedCOS (CBs-Tx) nanoparticles could be successfully prepared with a yield of 80%-90% and paclitaxel encapsulationof 54%-70%. The size of CB nanoparticles was in the range of 200-300 nm, and it increased to 300-400 nm after paclitaxelloading with the narrow size distribution maintained. Paclitaxel-loaded CBs (CBs-Tx) nanoparticles showed remarkablyhigh anticancer activity compared with paclitaxel in cremophore EL (CrEL)-ethanol against B16F10 cells. Theantitumor efficacy in vivo was shown with significant inhibition of the tumor growth in both paclitaxel-treated groups. Theeffect on tumor size by the paclitaxel in the CrEL-ethanol formulation appeared to be slightly larger than that in CBs-Tx. The decrease in cytotoxicity and the increase in antitumor activity may lead to the improvement in the therapeuticindex in clinical use compared to commercial paclitaxel. The efficacy of CBs-Tx nanoparticles suggests that bile acidas a hydrophobic group may have a potential application of effectively loading hydrophobic drugs such as paclitaxel.

      • KCI등재

        Blood-Compatible and Biodegradable Polymer-Coated Drug-Eluting Stent

        박준규,나재운,김동곤,배인호,임경섭,정명호,최창용,최수경,김상채 한국고분자학회 2015 Macromolecular Research Vol.23 No.3

        A drug-eluting stent (DES) is a metal stent that has been coated with a drug known to suppress restenosis. To prepare a novel DES, a bare metal stent (BMS) was coated with sirolimus (SRL) in a blood-compatible, biodegradablepolymer, poly lactic-glycolic acid, grafted with poly ethylene glycol (PLGA-PEG), by an ultrasonic spraymethod. The PLGA-PEG-coated DES was designed to control the drug release-rate by varying the PEG content inthe polymer. The release behavior of SRL from the DES showed a burst-release pattern in 7 days and then sustainedreleaseover 21 days. The amount of SRL released increased with increasing PEG content in the polymer up to 15%. The PLGA-PEG copolymer coated on the stent showed the potential to act as a bio-degradable drug reservoir. In anin vitro platelet adhesion test, the PLGA-PEG15-coated DES showed significantly reduced platelet deposition versusthe BMS. The DES revealed anti-thrombotic activity and blood-compatibility presumably due to the increasedhydrophilicity of the surface of the stent and the amount of SRL loading corresponding to the high PEG content in thepolymer. In an animal study, the restenosis rate was reduced in the PLGA-PEG15-coated DES group (20.2±11.02%)versus the BMS group (44.2±12.11%). The PLGA-PEG15-coated DES inhibited smooth muscle cell (SMC) proliferationand prevented in-stent restenosis (ISR) in in vivo test. We successfully obtained the PLGA-PEG15-coatedDES with smooth surface and sustained drug-release properties.

      • KCI등재
      • KCI등재

        정밀 위치결정 서비스에 연계한 국가 GNSS 인프라 활용현황 분석

        박준규,정갑용 사단법인 인문사회과학기술융합학회 2017 예술인문사회융합멀티미디어논문지 Vol.7 No.2

        GNSS(Global Navigation Satellite System) is positioning and navigation system using satellites. Accurate positioning is possible in all regions of the world using satellite signals. In Korea, GPS was introduced in the late 1980s. GPS is used in research and work in various fields such as navigation, surveying, and GIS. Since 1995, NGII(National Geographic Information Institute) has installed and operated CORS(Continuously Operating Reference Station) for the practical use of GNSS surveying, RINEX download and VRS(Virtual Reference Station) service was provided for precise positioning. Demand for these services is explosively increasing in the field of surveying. Therefore, there is a need for research to provide good service. In this study, status of national surveying infra structure was researched focused on CORS and its services. As a results, current status of CORS and service were presented. Users of VRS service has increased greatly. In order to provide stable service and advanced surveying, it is necessary to continuously upgrade services such as providing services for various GNSS satellites and securing stability through server redundancy in the data center. GNSS(Global Navigation Satellite System)는 인공위성을 이용한 위치결정 및 항법 체계로 인공위성 신호를 이용하여 전 세계 모든 지역에서 정확한 위치결정이 가능하다. 우리나라는 1980년대 말 GPS를 도입하였으며 항법 및 측량, GIS 등 다양한 분야의 연구 및 업무에 활용하고 있다. 국토지리정보원은 1995년부터 GNSS 측량의 실용화를 위해 위성기준점을 설치 및 운영하고 있다. 현재 RINEX 데이터 다운로드, VRS 등 위치결정을 위한 서비스를 제공하고 있으며, 현재 측량 관련 분야에서 이러한 서비스에 대한 수요가 폭발적으로 증가하고 있어 향후 원활한 서비스의 제공을 위한 연구가 필요한 실정이다. 본 연구에서는 정밀 위치결정 서비스에 연계한 국가 GNSS 인프라 활용현황을 분석하였다. 연구를 통해 위성기준점 관련 서비스 현황의 변화를 파악하였으며, VRS 서비스의 이용자 수가 큰 폭으로 증가하고 있음을 알 수 있었다. 향후 안정적인 위치결정 서비스 제공 및 측량 선진화를 위해 다양한 GNSS 위성군에 대한 서비스 제공, 데이터 센터의 서버 이중화를 통한 안정성 확보 등 서비스의 지속적인 고도화가 필요하다.

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