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유전자변형 유채의 환경방출실험에서 격리포장 외부로의 도입유전자 이동가능성 모니터링
김도영,남기정,문예슬,김대인,김영중,문두범,천영진,남경희,안주희,이범규,윤길영,김신제,김창기 한국국제농업개발학회 2012 韓國國際農業開發學會誌 Vol.24 No.2
1. 본 연구에서는 GM 유채(Brassica napus)의 환경방출실험시의 안전관리를 위한 모니터링을 수행하였다. 2. 문헌조사를 통해 유채의 품종 순도 유지를 위한 격리거리와 교잡가능한 종을 확인함으로써 모니터링의 범위와 모니터링 대상 식물종을 결정하였다. 3. GM 유채의 격리포장으로부터 1.3 km 거리 범위 내에서 발견된 B. napus, B. juncea 및 B. oleracea를 대상으로 모니터링을 실시한 결과, 교잡을 통한 유전자의 유출은 발견되지 않았다. One of the main concerns in field trials of GM crops is transgene escape from GM crops to conventional crops or weedy (wild) relatives via pollen dispersal. The management of field trials is therefore aimed at the detection and prevention of hybridization between GM crops and their closely related species around the field. This study monitored the escape of introduced genes of GM oilseed rapes (Brassica napus) outside the trial site during a small-scale field trial. First, a monitoring area (up to 1.3 km from the isolated field site) was determined according to recommended isolation distances for maintaining varietal purities of oilseed rapes. Then, target species (B. napus, B. juncea and B. oleracea) for monitoring were chosen using a literature search of plant species reproductively compatible with oilseed rapes. Hybrids between GM oilseed rapes and sexually compatible species were not detected and this result indicated that transgene escape outside the trial site did not occur during a field trial.
김행진,김성진,정수미,유형천,전상윤,홍석,김방울,Kim, Haeng-Jin,Kim, Seung-Jin,Jeung, Su-Mi,Ryu, Hyung-Cheon,Jeon, Sang-Yoon,Hong, Seok,Kim, Bang-Oul 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2
Objective : This study was designed to evaluate the effects of oriental medicine therapy on a normal pressure hydrocephalus patient. Methods : The clinical data was analyzed on a patient with normal pressure hydrocephalus whose main symptoms were dementia, gait disturbance and urinary incontinence. The patient was admitted to the internal medicine department of Dong-shin University Oriental Hospital from December 7, 2002, and remaind until January 20, 2003. He was treated with herbal medicine(Yukmijiwhangtang), acupuncture and moxa therapy. Results : After treatment, improvement was seen in dementia, gait disturbance, and urinary incontinence. Conclusions : The study suggests that oriental medicine therapy is significantly effective on the treatment or normal pressure hydrocephalus.
모체 Thyroxine 투여가 태아알코올효과를 가진 흰쥐 대뇌겉질 및 해마에서 NPY함유 신경세포의 생후 발달에 미치는 영향
김복,박상기,박영란,김종중,문정석,김주수,문영민,현영식,천관영,정윤영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2
Background and Objectives: Maternal alcohol abuse is considered to be one of the most prominent cause of neurobiological malformations in the postnatal and adult life of the offspring. In this study, we investigated the effects of maternal alcohol drinking on the postnatal development of NPY-containing neuron, and, the influence of thyroxine treatment on the cerebral cortex and hippocampus of pups of alcohol abused mother. Materials and Method: Time-pregnant rats were divided into three groups. Alcohol-fed group A received 35 calories of liquid alcohol diet daily from gestation day 6; control pair-fed group B was fed a liquid diet in dextrin replaced alcohol isocalorically: alcohol + T4 group C received 35 calories liquid alcohol diet and exogenous thyroxine subcutaneously. Results: Group C showed prominent NPY immunoreactivity in the cerebral cortex compared to group A and B at P7. In group C, NPY-containing neurons were widely distributed in the all layers of cerebral cortex after P14. Besides, numerical decrease of NPY-containing neuron as age increases was not found in group C. However, the decrease of NPY-containing neuron was clearly observed in group A compared to group C after P14. In hippocampus, group Band C were appeared similar patterns after P7. Additionally, in group C, NPY immunoreactivity was prominently appeared in CA2 and CA3 at P14 as compared to group B. Conclusions: The present results showed the increase of intensity and number of NPY-containing neurons in cerebral cortex and hippocampus of pups of exogenous T₄ supplemented alcohol-exposed dams as compared to control pair-fed and alcohol-exposed pups at P7. It presumably suggest that NPY-containing neurons might be regulated by the early postnatal growth stimulatory effect of the exogenously supplemented T₄. Therefore, the increase of NPY synthesis caused by maternal administration of exogenous thyroxine may ameliorate fetal alcohol effect, one of the ill effects as a result of the dysthyroid state following maternal alcohol abuse.
경도 인지장애를 동반한 파킨슨 환자의 타이치 운동이 보행기능 및 체력에 미치는 영향
김권민(Kim, Gwon-Min),박종환(Park, Jong-Hwan),천상명(Chun, Sang-Myung),권유찬(Kwon, Yoo-Chan),김보건(Kim, Bo-Kun),박현태(Park, Hyun-Tae) 한국체육과학회 2018 한국체육과학회지 Vol.27 No.2
The purpose of this study was to the effects of taichi exercise program on gait parameter in parkinson"s disease with cognitive mild impairment patients. The exercise program consisted of taichi exercise program 90min/session, 2 days each week for 12 weeks. The results of this study were as gait parameter, Gait speed(p<.043), Stride length(p<.033), Stance phase duration(p<.008), Swing phase duration(p<.008), Double support duration(p<.006), Single support duration(p<.035) in Parkinson"s disease with mild cognitive impairment had a statistically significant. These findings suggest that The effect of disease specific taichi effective intervention strategy for positive gait parameter leading to improved in parkinson"s disease with mild cognitive impairment.