중수로 해체원전 계통제염 범위 평가

김초롱,김정주,김학수,박병호 한국에너지학회 2021 한국에너지공학회 학술발표회 Vol.2021 No.4

Erucamide from Radish Leaves Has an Inhibitory Effect Against Acetylcholinesterase and Prevents Memory Deficit Induced by Trimethyltin

김초롱,김회석,최수정,김재겸,김민철,김윤정,신동훈 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.8

In this study, we investigated a potent acetylcholinesterase inhibitor that was isolated from radish leaf (Raphanus sativus L.) extracts. Through sequential fractionation of radish leaf extract, the active constituent was identified as cis-13-docosenamide (erucamide). To validate the potency, erucamide derived from radish leaves was supplemented in diets and then fed to trimethyltin (TMT)-exposed mice. Specifically, mice had free access to a control diet or diets containing different concentrations of erucamide for 3 weeks, followed by an injection of TMT (2.5 mg/kg body weight). Our results showed that pretreatment of mice with erucamide (20 and 40 mg/kg body weight per day) significantly attenuated the TMTinduced learning and memory deficits that were assessed by Y-maze and passive avoidance tests. These findings suggest that radish leaves, and possibly its isolated erucamide, may have preventive effects against memory deficits related to Alzheimer’s disease by modulation of cholinergic functions.

Eco-friendly and biodegradable RFID chips

김초롱,이현호,허혜연,오승주,양종민,신성철,김길환,( Dhanashri Vitthal Desai ) 한국공업화학회 2021 한국공업화학회 연구논문 초록집 Vol.2021 No.0

유기산 종류 및 온도에 따른 니켈합금 산화막 제거율 평가

김초롱,김정주,이경희,조현준,김학수 한국에너지학회 2022 한국에너지공학회 학술발표회 Vol.2022 No.4

복합유체 제염 시 실리카 나노입자의 코발트 흡착 거동

김초롱,정종헌,윤인호,윤석본,양한범,최왕규,문제권 한국방사성폐기물학회 2014 한국방사성폐기물학회 학술논문요약집 Vol.2014 No.05

병원성미생물의 불활성화를 위한 산·알칼리처리가 양돈분뇨의 이화학적 성상에 미치는 영향

김초롱,김수량,김하제,전상준,한호,김동균,이명규,Kim, Cho-Long,Kim, Soo-Ryang,Kim, Ha-Je,Jeon, Sang-Joon,Han, Ho,Kim, Dong-Kyun,Lee, Myung-Gyu 한국축산환경학회 2012 축산시설환경학회지 Vol.18 No.3

본 연구는 구제역 긴급행동 지침 (SOP)에서 제시한 화학적 처리가 양돈분뇨의 이화학적 성상에 미치는 영향을 알아보고 이에 따른 적절한 후처리 방법을 모색하기 위하여 수행한 것이다. 가축분뇨의 알칼리처리-산중화 및 산처리-알칼리 중화처리는 처리조건에 따라 다양한 이화학적 변화가 있었으며, 이에 대한 결과요약은 다음과 같다. 1. B4 처리구 (Citric Acid-Calcium Oxide)의 경우는 산처리 후 알칼리 중화처리 시에 응고현상이 발생하였다. 이는 구연산과 생석회의 투입으로 인한 물질 간 화학적 결합에 기인하는 것으로 사료된다. 2. 산처리-알칼리 중화 (B처리구)의 모든 처리구에서 EC가 약 50 mS/cm 전후까지 증가 하였으며, A4 처리구를 제외한 알칼리처리-산 중화 (A처리구)에서는 처리 후 원수의 EC 보다도 낮은 경향을 나타냈다. 3. $NH_4{^+}$-N의 농도는 산처리-알칼리 중화 (B처리구)에서 처리 후 거의 변화가 없는 반면, 알칼리처리-산 중화 (A처리구)에서는 급격히 감소하였다. 이는 암모니아의 탈기로 인한 기작으로 사료되며, 특히 CaO를 이용한 A1, A2 처리구에서 두드러지게 나타났다. 4. 알칼리처리-산 중화 및 산처리-알칼리 중화는 처리조건에 따라서 이화학적 변화의 양상이 다양하다. 적정 pH 수준을 위한 시약의 소요량 및 운영관리 면에서 볼 때, 병원성미생물 등으로 오염된 가축분뇨 화학적 전처리시에는 산처리-알칼리중화 (B처리구) 보다는 알칼리처리-산 중화 처리구 (A처리구) 적합 할 것으로 사료된다. 그러나 자원화, 정화처리 등 후처리방법의 선정은 각 농가 및 지역적 환경요소에 따라 다르므로 산 알칼리제제의 소요량에 따른 경제성 평가 및 처리목적 등에 대한 충분한 검토가 필요하다. Disinfecting contaminated swine manure with FMD (Foot-and-Mouth Disease) and pathogenic viruses is very important for maintaining sanitized environment. However, very few research reported on this subject, especially post-disinfection to utilize the wastes as a renewable resource. This research is carried out to obtain basic information for chemical treatment in FMD SOP (Standard Operating Procedure, Korea) of contaminated swine manure. Using lime, sodium hydroxide, citric acid and hydrochloric acid, described in FMD SOP, the effects of chemical treatments on livestock manure were compared in this paper. Four combinations of alkali-acid treatments and four kinds of acid-alkali combinations were tested to find out the effective method. Total coliform bacteria in contaminated swine manure, $1.6{\times}10^4$ CFU/100 ml, decreased to the range of 1/1000~1/100 in all treatments. Some specific disinfectants increases BOD (Biochemical Oxygen Demand) and EC(Electric Conductivity), especially, alkaline treatments increases ammonia level than acid treatments. These findings suggest that the treatment methods should be considered as an important environmental factor in post-disinfection of contaminated animal manure with pathogenic microorganisms.

Neuroprotective Action of Deer Bone Extract Against Glutamate or Ab1–42-Induced Oxidative Stress in Mouse Hippocampal Cells

김초롱,전혜련,신숙경,김현정,안창원,정성욱,박수현,김미리 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.2

Water extracts of deer bone, called nokgol in Korean, and deer antlers have been traditionally used as antiaging medicines. Deer antler extract is known to possess various activities, including anti-aging or anti-amnesic activitiy. However, there are no reports about the neuroprotective effect of deer bone extract (DBE). The objective of this study was to examine the neuroprotective effect of DBE on glutamate-induced cell death of mouse hippocampal cells (HT-22 cells) and to elucidate the mode of neuroprotective action of DBE. In this study, HT-22 cells was pretreated with DBE before stimulation with glutamate, and then, the effects of DBE on cell viability, oxidative stress markers, and MAP kinases were determined. Separately, the effect of DBE on H2O2 or amyloid beta peptide (1–42) (Ab1–42)–induced cytotoxicity of HT-22 cells was evaluated. DBE protected HT-22 cells from glutamate-induced cell death and prevented the increase in lactate dehydrogenase leakage in HT-22 cells. DBE also prevented glutamate-induced oxidative stress, as indicated by increased reactive oxygen species and lipid peroxidation as well as by decreases in glutathione (GSH) levels and GSH peroxidase activity. In addition, DBE inhibited glutamate-induced activation of c-Jun N-terminal kinases ( JNK), p38, and extracellular signal-regulated kinase, indicators of oxidative stress-induced cell death. Furthermore, DBE also protected against H2O2 and Ab1–42-induced cytotoxicity. These results suggest that DBE may be a useful functional agent for the prevention against neurodegenerative disorders involving oxidative stress.

트라이벌무드 패션경향을 응용한 아트메이크업 개발 연구

김초롱,곽태기 한국패션디자인학회 2016 한국패션디자인학회지 Vol.16 No.4

현대패션에서 주목받고 있는 트라이벌무드 패션경향 요소들은 패션의 경계를 넘어 문화의 다양성을 가지고 트라이벌무드의 표현으로써 아트메이크업에 활용이 가능한 예술로 발전할 수 있다. 이에 본 연구는 이러한 트라이벌무드의 패션경향을 발표하고 있는 대표적인 여섯 명의 패션 디자이너 도나 카란, 비비안 웨스트우드, 마리아 그라지아 치우리, 피에르 파올로 피치올리, 미우치아 프라다, 준야 와타나베를 통해 트라이벌무드 패션경향 요소를 분석하여 아트메이크업 디자인 발상의 모티브로 활용하였다. 총 여섯 명의 디자이너들을 통해 트라이벌무드 패션경향의 문양, 소재, 색채, 장식 및 디테일 요소를 분석하고 도출된 요소들을 아트메이크업에 접목하여 독창적이고 창의적인 예술적 표현 가능성을 제시하는 것에 목적이 있다. 이를 바탕으로 한연구의 결과는 다음과 같다. 첫째, 문양 요소는 동물 문양, 줄무늬 문양, 기하학 문양, 둘째, 소재 요소는 가죽소재, 모피 소재, 깃털 소재, 셋째, 색채 요소는 브라운 계열 색채와 비비드 색채, 장식 및 디테일 요소는 비즈, 테슬, 자수, 다양한 소재의 액세서리, 위의 내용으로 정리될 수 있고 위의 요소 중 장식 및 디테일 요소가다른 요소들과 비교하여 다양한 자연적인 소재의 활용으로 가장 적극적으로 트라이벌무드를 표현할 수 있었다. 문양 요소와 장식 및 디테일 요소의 자수 요소는 아트메이크업의 구도 계획 단계에서 적절한 자료가 되었고, 소재 요소와 장식 및 디테일 요소의 다양한 원시적인 요소들은 아트메이크업에 폭넓게 활용될 수 있었다. 이처럼 트라이벌무드 패션경향 요소들은 다양한 방법으로 활용되어 아트메이크업의 표현 방법 영역을 확대할 수 있었다. 본 연구를 통해 아트메이크업 분야의 창작 활동 표현 범주의 확대를 가져올 수 있을 것이라기대하고, 다양한 패션스타일의 예술적 양식을 기반으로 창의적인 아트메이크업 연구의 가능성을 제시하는바이다. Factors of Tribal mood fashion, which are underlined and have cultural varicosity in modern fashion would be able to develop as applicable art in art makeup beyond fashion area. Therefore, this study analyzes representative six fashion designers, Donna Karan, Vivienne Westwood, Maria Garazia Chiuri, Pier Pierpaolo Piccioli, Miuccia Prada and Junya Watanabe. All these designers have presented tribal mood fashion. Through analysis of these designers, factors of expression trend of tribal mood fashion have understood and then, these factors have been applied as art makeup source. The aim of this study is analyzing six designers’ expression trend of tribal mood fashion, and figuring out pattern, material, decoration and detail factors of expression trend of tribal mood fashion, then, presenting a development possibility of creative art makeup by applying these factors. Findings of this study are as follows. Firstly, pattern factors are comprised of animal pattern, strip pattern and geometric pattern. Secondly, material factors are comprised of leather, fur and feather. Lastly, decoration and detail factors are comprised of beads and tassel. Among these three elements, decoration and detail factors are able to present various tribal mood actively because of availability of using various natural materials. In addition, material factors and decoration and detail’s primeval materials could be applied widely with basic elements of art makeup such as color and texture. Pattern factors and decoration and detail’s embroidery factors are suitable material to composition of art makeup. Therefore expression trend of tribal mood fashion may lead to extension of art make-up’s expressive method.

EMG Study for Muscle Activation during Variable Gait Training in Stroke Patients: Stepper Climbing, Stair-up and Level-ground Gait

김초롱,최성진,신원섭 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.6

Purpose: The purpose of this study was to compare muscle activation patterns of lower extremities in stroke patients during stepper climbing, stair-up, and level-ground gait conditions by surface electromyography (EMG). Methods: Subjects included 19 hemiplegic patients comprehensive rehabilitation center for inpatients with stroke. Surface EMG was used to measure the subjects’ medial gastrocnemius (GCM), tibialis anterior (TA), biceps femoris (BF), and rectus femoris (RF) activity as they took six steps during stepper climbing, stair-up, and level-ground gait conditions. Results: There was no significant difference in the BF or RF muscle activity for the stepper climbing, stair-up, and level-ground gait conditions. However, there were significant differences in the medial GCM and TA muscle activity between each condition on the patients’ hemiplegic side(p<0.05). There was significant difference in the medial GCM, TA, RF, and BF muscle activity between each condition on the patients’ non-hemiplegic side (p<0.05). Conclusion: As a result, the overall muscle activity during the level-ground gait was higher than the stair-up condition, and the muscle activity during the stair-up condition was higher than the muscle activity during the stepper climbing condition. As one of the many methods used for gait training, we suggest that the stepper exercise could be applied at an earlier stage in the gait training process.

Rubus coreanus Miquel Inhibits Acetylcholinesterase Activity and Prevents Cognitive Impairment in a Mouse Model of Dementia

김초롱,최수정,오승상,권윤경,이나영,박귀근,김연정,허호진,전우진,박증석,신동훈 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.9

To find acetylcholinesterase (AChE) inhibitors for the prevention of neurological disorders, such as Alzheimer’s disease, ethanol extracts of promising traditional edible Korean plants were tested. Among them, Rubus coreanus Miquel extract exhibited the most significant AChE inhibitory activity. The effect of R. coreanus extract on trimethyltininduced memory impairment in mice was investigated using Y-maze and passive avoidance tests. Our results showed that administration of R. coreanus extract significantly improved alternation behavior and step-through latency. In addition, R. coreanus extract was sequentially fractionated, and the purified constituent was determined to be 3,4,5-trihydroxybenzoic acid.