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      • 家兎肺 抽出液과 洗滌液의 表面活性度와 In Vitro X線照射가이에 미치는 影響

        權得基,朱永恩 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.16 No.1

        家兎肺에서 얻은 推出液(extracts)과 洗滌液(washings)의 肺胞表面 活性物質의 活性度와 蛋白含量을 比 較하고, 나아가서 300R, 600R 및 1,000R의 X線을 in Vitro로 照射하여 20℃에서 1,4,8,12 및 24時間에 各各 表面活性度와 蛋白含量을 測定하여 果 다음과 같은 結果를 얻었다. 1. 正常對照群의 肺洗滌液의 最大 및 最小 表面張力, 幅, S^- 및 蛋白含量은 各各 44.1dyne/cm, 8.0dyne/cm, 14.2dyne/cm, 1.38 및 115.8mg/ml이었고 肺推出液의 그것들은 各各 36.8dyne/cm, 13.6dyne/cm, 9.2dyne/cm, 0.91 및 884.7mg/ml이었다. 2. 肺洗滌液이나 肺推出液에서 모두 20℃에서 實驗 24時間까지 肺胞表面活性度나 蛋白含量은 큰 變化를 나타내지 않았다. 3. 300R의 in Vitro X線 照射로서는 各 實驗値가 對照에 比하여 큰 差異를 나타내지 않았으나, 600R 또 는 1,000R의 in Vitro對照로서는 對照群에 比하여 各實驗値에서 若干의 差異를 나타내었으며, 特히 最小 張力에서 그 傾向이 뚜렷하였다. 4. 以上의 結果로서, 肺胞表面活性度測定에는 肺推出液보다 肺洗滌液을 使用함이 더 有利하고 20℃에서 肺洗滌液을 保存하여도 그 活性度나 蛋白含量에 差異가 없음을 알 수 있다. 또한 X線 in Vitro 照射는 肺胞表面活性物質에 큰 變化를 나타내지 않는 것이라고 思料된다. The extraction method of preparing the pulmonary surfactant is crucial in determining and evaluating the surfactant activities in situ. In the present study, two most commonly used methods were compared; namely, the extracts and washings. Also, in an attempt to clarify the effect of X-irradiation on the pulmonary surfactant system, X-ray of 300R, 600R and 1,000R, respectively was irradiated to the lung extracts and lung washings obtained from the rabbit in Vitro, and the pulmonary surfactant activities as well as the protein contents of both extracts and washings were studied at 1, 4, 8, 12 and 24 hours after the irradiation at 20℃. The results obtained are summarized as follows: 1) The maximal and minimal surface tensions, width of the tension-area diagram at the surface area of 40%, stability index and protein content of the lung washings in the non-irradiated normal group was 44.1 dyne/cm, 8.0 dyne/cm, 14.2 dyne/cm, 1.38 and 115.8 mg/ml, respectively. In the lung extracts, the value was 36.8dyne/cm, 13.6dyne/cm, 9.2dyen/cm, 0.911and 884.7mg/ml, respectively. 2) In the normal group, both the lung washings and lung extracts showed no noticeable change in the pulmonary surfactant activities and protein contents upto 24 experimental hours at 20℃. 3) X-irradiation of 300R in Vitro produced no meaningful change in the surfactant activities or protein contents from the control, but 600R and 1,000R of X-irradiation showed a tendency of sligt changes in the surfactant activities from the control with the increased values of the minimal surface tensions. 4) From the above, it may be considered that the lung washings are better suited than the lung extracts for the measurement of the pulmonary surfactant activities. Also, at 20℃, the pulmonary surfactant activities as well as the protein contents do not seem to be altered greatly for at least 24 hours. Finally, X-irradiation in Vitro does not seem to produce any noticeable change in the pulmonary surfactant.

      • 복합열화환경 하에서의 단면복구재의 철근부식특성 평가에 관한 실험적 연구

        김영덕,박종호,조봉석,김용로,권영진,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

        The duties of the restorative material are to bear up against stress and to protect reinforcement corrosion. So the restorative material are estimated by various kinds of strength, permeability and etc. But to evaluate performance of the restorative material accurately, it is necessary to estimate their reinforcement corrosion directly in environment of combined deterioration. In this study, to evaluate performance of restorative materials, we compare their properties in terms of compressive and bending strength and permeability of water and air with actual reinforcement corrosion like ratio of corrosion area, weight reduction and corrosion velocity of steel bar under environment of complex deterioration. The results showed that strength and permeability of restorative materials are similar but their reinforcement corrosions are very different. And there is a case that strength and permeability of restorative material are better than normal concrete but reinforcement corrosions are worse.

      • 근위 대퇴정을 이용한 대퇴 전자부 골절의 치료

        문영완,서동현,강신택,권덕주,지용남,이기병 대한골절학회 2003 대한골절학회지 Vol.16 No.1

        목 적 : 근위 대퇴정을 이용한 고령 환자의 대퇴전자간 골절의 치료결과에 대해 보고하고자 한다. 대상 및 방법 : 2001년 4월부터 2002년 2월까지 대전자부에서 소전자에 이르는 횡선골절 및 소전자 주위 분쇄골절로 압박고 나사 고정이 용이하지 않은 전자간 골절, 일반적인 전자간 골절에 대해 근위 대퇴정을 사용해 치료한 80례 중 추시가 가능했던 71례를 대상으로 하였으며, 추시과정 중 골유합 시기, 대퇴경간각, 지연나사의 활강, 수술시간 및 출혈량, 술중 및 술후 합병증 수술시 주의사항을 조사하였다. 결 과 : 평균연령은 77.5세, 평균추시기간은 9개월이었다. Evans의 분류법으로 골절을 분류하여 안정성, 불안정성 골절은 30례, 41례였다. 평균 골 유합 시비는 13.8주였고, 대퇴경간각은 수술직후 131.9 ± 5.21˚, 129.9 ± 6.04˚ 였으며 평균지연나사의 활강은 4.21±4.13㎜였다. 수술시간은 평균 61분, 출혈량은 평균 0.67pint(134cc)였다. 술중 합병증으로는 정복 실패 1례, 원위고정나사 삽입시 피질골 골절 1례, drill bit 파손 1례가 있었으며, 술후 합병증으로는 대퇴 경간각 소실(5도이상) 12례, 경부골절의 발생이 2례, 지연나사의 관절내 돌출 1례였다. 결 론 : 대퇴골 전자부 골절의 치료로 근위 대퇴정은 정확한 삽입 위치, 삽입시의 조심스러운 확공, 지연나사의 연골하 골에 단단하게 고정시키는 등의 주의를 한다면 수술시간, 출혈량 감소 등의 술중 합병증을 줄이고, 견고한 내고정을 통한 조기 보행을 가능하게 하며, 좋은 골유합 등이 기대되므로, 특히 고령, 분쇄골절, 역행성 골절, 골다공증이 심한 경우에서 바람직한 수술방법으로 사료된다. Purpose : To evaluate the treatment results of geriatric intertochanteric fractures using a proximal femoral nail. Materials and Methods : From April 2001 to February 2002, 71 cases of the intertrochanteric fractures involving lesser trochanter, transverse or reverse oblique intertrochanteric fracture. We evaluated the bone union time, neck-shaft angle, lag screw sliding by follow up radiographs, operation time, blood loss and complications. Results : The average age was 77.5 years old, the mean duration of follow-up was 9 months and the mean duration of bone union was 13.8 weeks. The average neck-shaft angle on immediate postop. x-ray was 131.9 ± 5.21˚ and 129.9 ± 6.04˚ at last follow up and the average lag screw sliding was 4.21 ± 4.13㎜. The average operation time was 61 minutes and blood loss was 0.67 pints(134cc). Intraoperative complications were inadequate reduction in one case, difficulty in distal transfixing in one case and drill bit failure in one case and postoperative complications were loss of neck-shaft angle(more than 5 degree) in 12 cases, femur neck fracture in 2 cases and intraarticular cutting out of femur neck screw in one case. Conclusions : The use of the proximal femoral nail could be appropriate for the fixation of communited or reverse oblique intertrochanteric fracture in elderly, osteroporotic patients for early ambulation, preventing shortening and rotation deformity, and reducing operation time and blood loss.

      • KCI등재

        시스템 다이내믹스를 이용한 간호단위별 간호인력 산정에 관한 연구

        김문실,성영희,권경자,김도형,김정아,신덕신,유인자,유재국,이현숙 병원간호사회 2006 임상간호연구 Vol.11 No.2

        Purpose: The purpose of the study was to forecast manpower by building the nursing manpower-staffing model(surgical-medical nursing unite). Method: The system dynamics approach was adapted to build a simulation model for calculating medical-surgical nursing manpower-staffing. The model was built up on Venism 5.0b DSS. Result: The results in the basic circumstance are in following. The level of nursing service quality, patientsatisfaction, and nurse job satisfaction maintains higher at medical-surgical nursing unit of the tertiary hospitals with the ratio of bed to nurse 2.5:1-3.0:1 than at any other situations. The level of nursing service quality, patient satisfaction, and nurse job satisfaction maintains higher at madical nursing unit of the secontary hospotals with the ratio of bed to nurse 3.0:1 and at surgical nursing unit of the secondary hospitals with the ratio of bed to nurse 3.0:1-3.5:1 than at any other situations in the fundamental from. The results in the simulation circumstance are in following, As author raises the operating rate of bed into 95-100%, and cut skilled nursing staff down, the level of nursing-service quality, patient satisfaction, and nurse job satisfaction drops slightly. Conclusion: In terms of economic efficiency on tertiary hospotals, the ratio of bed to nurse for the best reasonable medical-surgical nursing manpower-staffing is 3.0:1. In terms of economic efficiency on secondary hospitals, the ratio of bed to nurse for the best reasonable medical nursing manpower-staffing is 3.0:1 and surgical nursing manpower-staffing is 3.5:1

      • 요하지통 환자에서 두 개의 캐눌라를 이용한 박동성 고주파 신경근 응고술의 임상 연구

        김천숙,배재영,배덕구,강규식,안기량,권진형,김지은,유시현 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

        Dorsal root ganglion(DRG) block by the local anesthetics and steroids which has done classically in low back pain(LBP) patients with radiculopathy has high incidence of recurrence rate and side effects of steroids. Recently a new technique of pulsed radiofrequency thermocoagulation(P-RFTC) was introduced and substituted for it because of the benefits such as relatively low recurrence rate, low risk of nerve injury and comfort during the procedure. We experienced 15 patients who had LBP with radiculopathy and no or little response to epidural steroid injection. When we performed DR ganglionotomy by P- RFTC under the C-arm guide in these patients, we tried to approach the exact DR ganglion using tow cannulas - the one for obtaining patient's subjective symptoms and injection of contrast dye, the other for making a RF lesioning after identifying the impedance of sensory and motor stimulation. In conclusion, DR ganglionotomy by P- RFTC using two cannulas in LBP patients is an easy and safe procedure with satisfactory results.

      • 뇌의 미만성 축삭 손상 정도, 지능 지수 그리고 예후와의 상호관계

        양승민,김영백,권정택,박승원,황성남,최덕영 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.2

        Diffuse axonal injury (DAI) is defined as posttraumatic coma for over 24 hours without intracranial mass lesion. the purpose of this study was to examine the neurologic state of the patient and to evaluate the psychiatric sequela after DAI by psychometric analysis.Twenty eight patients with DAI were analyzed by a psychoanalyzer. Electroencephalography and magnetic resonance(MR) imaging were performed on eighteen patients. The ratio of male to female was about 6 to 1 and the major cause was traffic accident followed by fall down. Radiologic abnormality in MR image was predictors of poor outcome and early neurologic state was one of the most significant prognostic factor. Psychometric anlysis revealed that lntelligence Quotient was correlated with outcomes and most of patients with DAI were in normal range of lntelligence Quotient(67.9%) but they have suffered from variable psychologic problems, such as depression, anziety, phobia and dementia. Previous studies in DAI have been based principally on the prognostic factors and treatment without a systemic apporach to their meurologic and psychologic problems. Psychometric analysis can reveal psychologic symptom in the patients with DAI and appropriate management of their psychiatric problems may carry important implications for management of patients with moderate or servere DAI and improve rehabilitation outcomes.

      • 플라즈마 표지소자의 제작

        이상윤,라병욱,박동수,황인헌,이덕동,신영남,박성배,이동욱,박용석,박형근,손상호,권태근,채경락,정경득 慶北大學校 自然科學大學 1986 自然科學論文集 Vol.4 No.-

        An Ac-type Plasma Display Panel (PDP) operating with Ne-Ar(0.1%) Penning mixture gas is fabicated. The characterics of the panel with electrodes covered with thin and thick dielectric layers are studied. The brightness of the Neon-orange light emitted by the panel measured as function of applied voltage and frequency. As an application, a graphic display system equipped with PDP showing still and moving pictures is made.

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