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Pattern Visual Evoked Potential as a Predictor of Occlusion Therapy for Amblyopia
( Woo Suk Chung ),( Sa Min Hong ),( Jong Bok Lee ),( Sueng Han Han ) 대한안과학회 2008 Korean Journal of Ophthalmology Vol.22 No.4
Purpose: This study was conducted to investigate the role of the pattern visual evoked potential (pVEP) as a predictor of occlusion therapy for patients with strabismic, anisometropic, and isometropic amblyopia. The secondary aim was to compare the characteristics of pVEP between strabismic and anisometropic amblyopia. Methods: This retrospective comparative case series included 120 patients who had received occlusion therapy or a glasses prescription for correction of strabismic, anisometropic, and isometropic amblyopia (20 patients had strabismic amblyopia, 41 patients had anisometropic amblyopia, and 59 patients had isometropic amblyopia). For each patient, the value of the P100 latency on pVEP at the time of the initial diagnosis of amblyopia was collected. Subsequently, the P100 latency was compared according to types of amblyopia. Fifty of 120 patients (7 patients with strabismic amblyopia, 21 patients with anisometropic amblyopia, and 22 patients with isometropic amblyopia) who were followed-up for longer than 6 months were divided into two groups based on the value of their P100 latency (Group 1, P100 latency 120 msec or less; Group 2, P100 latency longer than 120 msec.) The amount of visual improvement after occlusion therapy or glasses was compared between two study groups. Results: The mean P100 latency was 119.7±25.2 msec in eyes with strabismic amblyopia and 111.9±17.8 msec in eyes with non-strabismic (anisometropic or isometropic) amblyopia (p=0.213). In Group 1, the mean visual improvement after occlusion therapy or glasses was 3.69±2.14 lines on Dr. Hahn`s standard test chart; in Group 2, the mean improvement was 2.27±2.21 lines (p=0.023). Conclusions: The P100 latency on pVEP at the time of initial diagnosis was significantly related to the visual improvement after occlusion therapy or glasses in patients with strabismic, anisometropic, and isometropic amblyopia. Therefore, it was presumed that patients with a delayed P100 latency might have less visual improvement after occlusion therapy or glasses. In addition, there was no apparent difference in P100 latency between patients with strabismic and non-strabismic (anisometropic or isometropic) amblyopia. Korean J Ophthalmol 2008;22:251-254
조사선(VVCHO Sa Sun),조경제(CHO Kyung Je),이경훈(LEE Kyung Hoon),이왕재(LEE Wang Jae),이원복(LEE Won Bok),정인혁(CHUNG In Hyuk),서영석(SUH Young-Suk),강호석(KANG Ho Suck),이무삼(LEE Moo Sam),정진웅(CHUNG Jin Wong),고정식(KO Jeong Sik 대한체질인류학회 1991 대한체질인류학회지 Vol.4 No.1
저자들은 좌강신경이 골반에서 하지로 나오는 과정에서 좌골구멍근과 유지하는 밀접한 관계를 조사하여 그 연이의 유형과 빈도를 받히고자 한국인 시제의 하지 428 예를 해부하여 관찰하였던바 다음과 같은 결과를 얻었다. l. 좌골신경이 좌골구멍근 밑으로 나오는 경우는 전체의 76.7% (328예) 이었고 (Type A), 좌골구멍근 위로 나오는 것은 전체의 0.2% (1예) 이었다 (Type F). 2. 좌골신경이 좌골구멍근을 관통하는 경우는 전체의 19.3% (82예) 이었는데, 이중에서 72 예에서는 비골신정부가 근육을 관통하였으며 (Type B), 7예에서는 경골신경부가 근육을 관통하였고 (Type D), 3예에서는 비골 및 경골신경부 모두가 근육을 관통하였다. (Type E) 3. 좌골 및 경골신경부로 갈라져 좌골신경의 밑과 위로 각각 나오는 경우는 전체의 3,8% (17예)이었다. (Trpe C) 4. 좌골신경의 좌골구멍근에 대한 연이를 가장 흔한 전형적인 유형 (Type A)과 비전형적인 유형 (TW BCDE)으로 구분하여 남녀 및 좌우측에서 각각 관찬하였던바 남성의 정우 전형적인 유형은 78.5% 비전형직인 유형은 21.5% 이었으며 여성의 경우는 각각 736% 와 26.4% 등 차지하였다 5. 오른쪽 하지에서는 선형적인 유형이 77.1%, 비선형적인 유형이 22.9% 이었으며, 왼쪽하지에서는 75.3% 와 24.7%를 각각 차지하였다
김현숙,김혜정,김효진,신은경,오영숙,장혜숙,홍사복 연세대학교 생활과학대학 1985 婦學 Vol.18 No.-
This study was carried out to find the present condition of clothing life and functional clothing for the feebleminded children. The data for this study were collected from 36 nurses who were employed by the Holt Welfare Town in Ilsan. This study was done during April through November, 1984. The results of this study were as follows: 1. The garments preferred by the boys were Tshirts, long trousers and short pants, while that preferred by the girls was onepiece dress. 2. The convenience of dressing and undressing in clothing life was required because it was necessary to help the children dress and undress. 3. A convenient clothing was required for playing; Half front opening or front opening of an upper garment, round or Vneck collars and cuffsless or elastic corded cuffs were desirable. Front opening of pants was desirable. Some necessary attachments for convenient clothing were zipper, snap, big button and velcro. Articles required for dressing were vinyled pinafore and diaper. It is necessary to make and distribute clothing for feebleminded children which is functional and at the same time easy to wear and take off. And it is necessary to guide the children to dress and undress for the sake of themselves.
송유림,Jang Mi Hee,Jang Boyun,Bae Su Jin,Bak Seon Been,Lee Sung Min,Yun Un-Jung,Lee Ju Hee,Park Sang Mi,Jung Dae Hwa,Sa Bok Suk,Song Jong Kuk,이은혜,김광연,Park Kwang-Il,김영우,김상찬 대한독성 유전단백체 학회 2022 Molecular & cellular toxicology Vol.18 No.2
Background Herbal prescriptions have various effects and their efficacy is potentiated by the use of combinations of medicinal herbs. Objective Jageum-Jung (JGJ) is a traditional oriental medical prescription composed of five herbs. It has been used for detoxifi cation, and as an anti-inflammatory and antitumor agent. However, the effect of JGJ on hepatic fibrogenesis is unclear. Results We investigated the role of JGJ in TGF-β1/smad signaling, which is implicated in fibrogenesis, and its hepatoprotective effect in CCl 4 -treated mice with liver fi brosis. Treatment of LX-2 cells with TGF-β induced expression of mediators (α-SMA, PAI-1, and MMP-2) of fibrogenesis and activation of proinflammatory cytokines (TNF-α, IL-1β, and IL-6). However, these were downregulated by pretreatment with JGJ. In mice, oral administration of JGJ prevented liver injury induced by CCl 4 , as indicated by decreases in the ALT and AST levels. Conclusions JGJ inhibits hepatic fibrogenesis and TGF-β1/Smad signaling.