지방척수수막류 14례의 임상 분석 : Clinical Analysis of 14 Cases

이정호,신규만,김명현,송준혁,박향권,김성학,박동빈 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.6

Lipomyelomeningocele is the most common malformation leading to spinal cord tethering. Nonetheless, these lesion continues to pose a challenge in patient management. The purpose of this study was to identify the clinical feature, candidate for surgical repair, and outcome of lipomyelomeningocele in young children and adults. We studied the magnetic resonance images and/or lumbar myelo-CT of lipomyelomeningocele performed between January 1987 and September 1995 at our institutions and reviewed the pertinent medical records and radiologic studies to determine clinical feature, surgical candidate, and outcomes of these patients. Of the 14 cases(11 female and 3 males) studied, the most common factor that caused these patients to seek help was the cosmetic effect of the mass on their back, followed by urinary incontinence, and weakness of lower extremities. The patients' age ranged from 2 months to 21 years(mean, 5.0 years). All the patients underwent immediate surgical management that consisted of removal of lipoma, untethering of the cord, and complete dural sac repair. Follow up for these patients ranged from 6 to 82 months(median, 54 mo). None of the patients that underwent surgical correction before the emergence of neurological deficit had ever developed neurological deficits at the end of the follow up. However a few of the patients, despite presented with neurological deficits or urinary incontinence at the time of surgery, improved significantly. In conclusion, early detection and prophylactic surgery is imperative to prevent permanent neurological deficits and urinary dysfunction.

흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.

Vibrio fluvialis의 혈청형과 생화학적 성상

임효빈,정성오,김신무 대한임상병리사협회 1993 대한임상병리사회지 Vol.25 No.1

Efficient Green Organic Light-Emitting Diodes by Plasmonic Silver Nanoparticles

Jeong Bin Shin,Se-Woong Baek,Seong Min Lee,Myeongcheol Kim,Jung-Yong Lee,Kyung Cheol Choi IEEE 2016 IEEE photonics technology letters Vol.28 No.3

<P>The resonance effect between the localized surface plasmon mode and the excited excitons in organic materials can enhance the optical and electrical performances of organic light-emitting diodes (OLEDs). Here, we show an enhancement in the luminescence efficiency of a green OLED by employing silver nanoparticles without an optical microcavity effect. The enhanced photoluminescence and exciton decay rate support the idea that the improved luminescence efficiency is due to the increased spontaneous emission rate of the emitter. Our results indicate that the plasmonic near-field interaction of the light-matter can be a strong engineering tool for high-efficiency organic optoelectronic devices in the display industry.</P>

A survey of knowledge and behavior regarding self examination of skin cancer

( Jeong Won Jo ),( Young Bin Shin ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: The recognition of self examination of cancer has increased more than before. Although skin cancers are almost always curable when found and removed early, most patients are little known about general awareness of skin cancer. Objectives: In this study, we survey on satisfaction of clinic education to the 40 patients treated with skin cancer and affection to behavioral change. Methods: We reviewed a written questionnaire and patients’ self-examination records including patients’ age, method of self-examination, and skin check point. Results: The most patients replay (90%, 36/40) and want to know the warning signs of skin cancer and what to look for during the self-examination (88%, 32/36). The results show the most of patients want to help you make the next your dermatologist’s appointment (81%, 29/36). At time of check self-examination, the patients use the record paper prepared from our clinic (69.4%, 25/36). Conclusion: Although the patients treated with precancer and cancer area aware that the risk of skin cancer and they want to know about self-examination of skin cancer. Therefore, most popular skin cancer education and prevention program include self-skin examination is more required and dermatologist should play a major role in this action.

Plasmonically Enhanced Optical Characteristics From Europium Organometallic Complex

Jeong Bin Shin,Seong Min Lee,Myeongcheol Kim,Donghyuk Kim,Duk Young Jeon,Kyung Cheol Choi IEEE 2013 Photonics Technology Letters Vol.25 No.23

<P>We demonstrated that the plasmonic effect can enhance the photoluminescence of the europium organometallic complex in conventional organic light emitting diodes stack from an anode to emissive layer with solution processing. The aggregated gold nanoparticles (A-Au NPs) were incorporated in poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) layer to increase the luminescent quantum efficiency of the emissive layer. An enhancement of 31% was achieved in the emission intensity at 614 nm for samples with A-Au NPs. The reduced exciton lifetime measured by time-resolved photoluminescence comply with the Purcell effect. These improvements are attributed to the localized surface plasmon of A-Au NPs increasing the electric dipole transition rate from Eu<SUP>3+</SUP> ions.</P>

[P336] Generalized cutaneous angiosarcoma associated with multiple myeloma

( Jeong Won Jo ),( Young Bin Shin ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Cutaneous angiosarcoma is a rare, malignant, vascular neoplasm of the skin commonly diagnosed in the head and neck regions. It arises infrequently in the lower extremity. In most cases, the exact etiology of cutaneous angiosarcoma is unclear. Recently, gene amplifications, especially MYC gene, have been identified as a new etiopathogenesis of angiosarcoma. MYC amplification may induce aberrant angiogenic phenotypes allowing the onset of the malignancy. Meanwhile, in multiple myeloma, MYC is activated and contributes to the malignant phenotype. Therefore, there is a possibility that MYC gene might be the common cause of angiosarcoma and multiple myeloma. Herein, we present the rare case of cutaneous angiosarcoma on lower extremity accompanied by multiple myeloma. An 85-year-old woman visited our department with multiple brownish to black colored nodules with hyperkeratotic crust, which were 0.3 to 0.8 cm in diameter, on the both feet and toes. The excisional biopsy was performed and a diagnosis of cutaneous angiosarcoma was made. At the time of visit, anemia, azotemia, proteinuria and hematuria were found. Immunofixation electrophoresis and bone marrow were performed, so multiple myeloma was diagnosed. We suspected carefully that MYC gene might be the common cause of angiosarcoma and multiple myeloma.

[P044] A case of pretibial thyroid dermopathy

( Jeong Won Jo ),( Young Bin Shin ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Pretibial myxedema(PM) is a dermatological manifestation of Graves` disease, which commonly presents as diffuse, non-pitting edema of shins and less often as plaques, nodules, or elephantiasis lesions mimicking lymphedema. Most common site is pretibial area and localized thickening of the pretibial skin causes deposition of acid mucopolysaccharides. There are 7 cases of pretibial myxedema reported in domestic dermatology literature. The only four of cases occurred after treatment of hyperthyroidism like that our case. Herein, we report a case of pretibial myxedema with Grave`s disease and Grave`s ophthalmopathy. A 51-year-old male visited our department with multiple erythematous patches and nodules on Lt. pretibial area. He had been diagnosed with Grave`s disease 6 months ago and Grave`s ophthalmopathy 3 months ago. The incisional biopsy on Lt. pretibial area showed mucinosis in dermis with perivascular lymphocytic infiltration. The lesions improved after steroid intralesional injection. For persisted local lesions despite improvement of systemic symptoms, we propose that the steroid intralesional injection may be an alternative to treatment.

[P046] Erythema multiforme with atypical clinical features

( Jeong Won Jo ),( Young Bin Shin ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Erythema multiforme (EM) is a hypersensitivity reaction characterized by targetoid skin lesions with or without erosions of mucosal surfaces. An acute, self-limiting or episodic course and the presence of targetoid lesions, raised atypical papules or mucosal involvement, are the important clues to diagnose with EM. Laboratory studies and skin biopsies are not required in all cases of EM. EM has been classified into a number of variants, mainly minor and major forms. In the case of general EM major, the mucosal lesions as well as the cutaneous lesions are also more severe and cover a wide range of skin surface. However, we examined a case of EM with atypical clinical features. Unlike general EM major, the cutaneous lesions of our patient were mild and limited to hands and feet that uncommonly involved, although the erosive lesions of oral and genital mucosa were severe. This atypical feature caused misdiagnosis to hand, foot and mouth disease and led to delay proper treatment. In conclusion, we should be recognized that there is a case of EM with atypical clinical features and refer to it when diagnosing.

[P337] Multiple skin tumors arising from a lesion of disseminated superficial actinic porokeratosis

( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Porokeratosis (PK) is a clonal epidermal disorder of keratinization characterized by annular lesions with an atrophic center and a hyperkeratotic edge. Six clinical variants are recognized. Among them, disseminated superficial actinic porokeratosis (DSAP) is characterized by the presence of multiple ring-shaped, keratotic and anhidrotic lesions of 0.5-1 cm in size, symmetrically distributed in light-exposed areas. A relationship between these lesions and malignancy was established by Taylor, who found a chromosomal instability in fibroblast cultures from PK lesions. The incidence of malignant degeneration in PK is approximately 7%, with large lesions, longstanding duration, the linear type and previous ionizing radiation being the greatest risk factors. We herein report a case of multiple skin tumors arising from a lesion of DSAP. A 78-year-old female presented with multiple brownish to black colored annular patches which began about 20 years previously and multiple black colored hyperkeratotic papules which began about 2 years ago. The histopathological findings of several biopsies had the characteristics of squamous cell carcinoma, squamous cell papilloma, keratoacanthoma including DSAP. We thought the long duration and large size of the DSAP lesions could be the risk factor of malignant degeneration.