산부인과 질환의 진단을 위한 자궁경의 활용

황윤영 中央醫學社 1987 中央醫學 Vol.52 No.6

지능적 웹 서비스 발견 시스템에서의 질의 처리

황윤영,유정연,유소연,이규철 한국정보과학회 2004 데이타베이스 연구 Vol.20 No.2

우리는 "시맨틱 웹 서비스를 위한 Topic MAps 기반의 온톨로지 언어" [7]에서 시맨틱 웹 서비스 발견 기술에서 사용되는 기존의 온톨로지의 한계점을 극복하여 지능적 웹 서비스 발견 시스템에서 필요로 하는 온톨로지의 구축 방법을 제안하였다. 본 논문에서는 제안된 온톨로지를 기반으로 지능적 웹 서비스 발견을 위해 사용자의 질의가 효율적으로 처리 가능하도록 질의 언어를 설계하였다. 또한, 사용자의 편의성과 효과작인 검색을 위한 질의 연산과정을 설계하고, 지능적 웹 서비스 발견 시스템인 TM-S(Topic Maps for Services) 시스템의 일부분으로서, TM-S의 질의 스키마와 질의 대수 및 질의 처리 알고리즘에 대해 상세히 기술한다.

사람 태반조직 Peroxidase의 부분정제 및 특성에 관한 연구

황윤영,차인돈,이희성 중앙대학교 의과대학 의과학연구소 1987 中央醫大誌 Vol.12 No.1

The purification and some properties of peroxidase of human term placenta was made in this study. The activity of peroxidase was measured by the method of Pu‥tter(1974). The results were summarized as follows; 1. The activity of peroxidase in cytosolic fraction of human term placenta was found to be 31.09 units per g wet tissue. 2. The peroxidase from human term placenta was purified about 22-fold by ammonium sulface precopitation and DEAE-cellulose column chromatography. 3. The most rapidly oxidized substrate was o-dianisidine. Benzidine, ascordic acid and guaiacol were oxidized with decreasing order of rats, while oxidation of dihydrooxyphenols and trihydrooxyphenol were very slow. 4. The partially purified peroxidase was strongly inhibited by i.omM of sulfhydryl reagents and cyanide. 5. The optimal tempreature for enzyme astivity was 40℃ and the optimal pH was 5.5. 6. The half life of the enzyme astivity was 30 min. at 60℃. 7. the Km values for hydrogen peroxid and guaiacol of peroxidase were 0.50mM and 0.44mM, respectively. 8. The purified enzyme was a typical hemoprotein.

입원환자의 수술경험

황윤영,양기우,채정선,이필호,장미,강미경,서효신,박성희,최경숙 중앙대학교 의과대학 간호학과 간호과학연구소 2000 중앙간호논문집 Vol.4 No.2

This study was to understan the experience of patients before and after operation with general anesthesia, and find specific nursing intervention unique to each patients so that they could keep peaceful mind and recover sooner. Patients in front of operation would experience anxiety and even emotional crisis in almost of them even though individual variation. To provide effective nursing care to them, it is essential to estimate nd understand the experiences of subjects. So this study is aimed to estimate the experience of patients in perioperative period in view of them. Subjects were 25 adult patient over 20 years who had been operated under general anesthesia in one university hospital in seoul. They did not have any special complication or psychological problem or change consciousness in perioperative period and agree this study. Data were gathered through in - depth interview using open and unstructive questions. Interview was done twice per one patients before and after 3 days of opeartion in their room and each interview tooks 30 - 40 minutes. Data analysis tool was Giorgi's phenomenological analysis method. Result were as follows ; 1) preoperative experiences of the patients were categorized into "Anxiety" "Hoping·Wishing" and "Transcendental Attitue" 2) postoperative experiences of the patients were categorized nto "Comfortability" "Hoping·Wishing" and "Dissatisfaction" Before operton most patients felt anxiety on the possibilities of operative pain, complication of failure of awakening from anesthesia. But patients tried to keep peaceful mind expecting good results or relying on medical teams. After opearton most patients felt comfortability and dissatisfaction a special treatment to reduce patients dissatisfaction. For satisfaction that perioperative nursing needs of the patients in admission is above all nurse's supporting and thinking patient's situation and specific nursing care to unique patients. Specially, patient's satisfaction that important role of operation room nurse to provide information and emotional support in opeartion waiting room and operation room. Therefore nursing intervention developed in properly operation waiting room and operation room and then performed by operation room nurse. Suggestions for further studies as follows ; 1) various approach for supportive nursing intervention methods by that perioperative patients in admission could be opearted and recovered in more comfortable state. 2) further study about perioperative nursing needs of the patients in same operation would be needed.

생리주기에 따른 자궁내막세포에서의 Transforming Growth Factor-β1 , β2의 발현 : 폐경기 내막과 임신중 탈락막세포와의 비교 In Human Endometrium through the Menstrual Cycle

황윤영,황정혜,장세진 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.9

Objectives : The purpose of this study was to determine the differences of expression of TGF- βS(TGF-β1 and TGF-β2) in the human proliferative endometrium, secretory endometrium, and the decidua during early pregnancy. And we also have studied the endometrial expression of TGF-β1 and TGF-β2 in the menopause and compared that to the expression in the endometrium and decidua. Methods : We have studied the expression of TGF-β1 and TGF-β2 by immunohistochemical staining method in the proliferative endometrium, secretory endometrium, decidua during early pregnancy, and menopausal endometrium. Results : In the epithelial cells, TGF-β1 was moderately expressed in the secretory phase and was weakly expressed in the proliferative phase and menopause. In the stromal cells, TGF-β1 was not expressed in the whole menstrual phase and menopause. And in the epithelial cells, TGF-β2 was moderately expressed in the proliferative phase, secretory phase, and menopause. In the stromal cells, TGF-β2 was not expressed in the whole menstrual phase and menopause. Especially, TGF-β1 and TGF-β2 were markedly expressed in the decidua during early pregnancy compared to the expression in the proliferative, secretory endometrium, and menopausal endometrium. Conclusions : These findings suggest that TGF-β1 may have an important role in the epithelial cells during the secretory phase, not stromal cells. And TGF-β1 and TGF-β2 may have a paracrine and autocrine role in the decidua/trophoblast interaction during pregnancy , especially in the normal pregnancy.

일 지역 노인의 건강인식과 건강행태에 따른 우울

황윤영,주민선 지역사회간호학회 2007 지역사회간호학회지 Vol.18 No.4

Purpose: This study was performed to understand health perception, health practice, and depression of the elderly and to identify their depression level according to health perception and health practice. Method: The subjects were 463 elders who have lived in the Jeju Island, and data were collected from June to August in 2005. Data were analyzed by SPSS 10.0. Result: The mean score of depression was 12.94 out of 30, and had a statistically significant correlation with educational level (F=2.943 p=.033), occupation (F=4.611, p= .010), and the number of chronic diseases (F=5.303, p=.001). When the cutoff of 18 points was applied based on Jung et al. (1997), the depression ratio was 12.4%, and when the cutoff parameter by Yesavage et al (1993) was applied, themoderate depression ratio was 74.8% and the severe depression ratio was 3.4%. In health recognition, consideration of usual health state had a significant correlation with depression (F=3.553 p=.007), but consideration of health state compared to the previous year wasn't. In health practice, sleeping was in a significant correlation with depression (F=3.574 p=.011), but smoking, alcohol drinking, exercise, and rest were not. Conclusion: Based on above results, we need further study on another sample group and the development, application, and verification of health management, education, and counseling programs for the elderly. Also, additional research should be made on significant factors of elderly depression.

원인불명 습관성 유산 환자에서 정맥내 인혈청 면역글로부린 투여 효과

황윤영,이재억,문형,박문일,정성노,황정혜,신중식 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.7

한양대학병원 산부인과 `습관성 유산 클리닉`에 등록된 동종면역성 요인 및 원인불명 습관성 유산환자로 분류 21명(23예)을 대상으로 최초 임신 진단시 면역글로부린 0.5/kg을 초 투여한 후 매 3주마다 1∼3회 투여 후 다음과 같은 결과를 얻었다. 1. 23예의 면역글로부린 투여환자 중 17명이 분만에 성공하였고, 4명은 유산하였지만 이 중 2명은 다음 임신 에서 재투여 후 만삭아를 분만하였다. 2명은 추적 관찰 도중 주소 변경으로 계속적인 추적이 불가능하였다. 2. 17명의 환자 중 7명은 질식분만, 10명은 제왕절개 술로 생존아를 분만하였다. 이 중 2명은 각각 36주와 37 주에 조기분만 하였지만 나머지는 만삭분만을 하였다. 3. 차단항체 지수(BEI)의 변화는 최초 면역글로부린을 투여하였던 23예에서 임신 전의 BEI 평균치(BEI-1) - 3.23±31.42%(분포: -53.6∼75%)에서 면역글로부린 1차 투여 후 20명의 환자에서 측정된 BEI 평균치(BEI-2)는 21.81±30.31%(분포: -42.2∼75%), 2차 투여 후 5명의 환자에서 측정된 BEI 평균치(BEI-3)는 14.34±14.24%(분 포: -10∼26.5%)로 각각 증가하였다. 이 연구는 면역글로부린의 기전이 아직 확실하지는 않지만 투여 후 혈청내 차단항체의 증가가 동종면역성 요인 및 원인불명 유산환자를 치료할 수 있다는 가정 하 에, 부작용이 적고 임신중 투여가 가능한 점에서 실시되 었다. 결론적으로는 생존아 분만에 높은 성공률을 나타 냈지만 대조군의 설정과 위약의 사용을 이용한 전향적 인 이중 맹검법이 불충분한 점, 그리고 Table 3의 BEI-3 에서와 같이 적은 개체 수(5예)로 인하여 객관성 결여 등 이 문제점으로 제시되었다. 또한 고비용의 치료제제 및 투여를 위해 환자가 입원을 해야 하고, 환자 및 보호자의 동의가 있어야 하는 등의 여러 제한요소가 뒤따른다. 하 지만 면역글로부린 투여 후 대부분의 환자에서 BEI 수치 가 증가되었고, 또한 결과적으로 본 교실 연구뿐만 아니 라 다른 보고에서도 높은 성공률을 나타내고 있다. 따라 서 다른 약제 투여와의 지속적인 연구가 비교 및 검토될 때 향후 원인불명 환자에서 치료 방법의 하나로 채택될 수 있을 것으로 사료된다. Intravenous human immunoglobulin (IVIG) has been proposed in patients with unexplained recurrent spontaneous abortion (RSA). Twenty-one women with a history of recurrent spontaneous abortion were treated with IVIG. Among them, 2 patients miscarried and were treated with immunoglobulin again during their next pregnancy (N=23). At the time of diagnosis of pregnancy, patients were treated with 0.5 g/Kg dose of IVIG. Therapy was repeated every 3 weeks at a dose of 0.5 g/Kg until 13 week`s gestation. Of these patients, Blocking Effect Index (BEI) was peformed before and after treatment, respectively. The results were as follows ; 1. Of 23 pregnancies participating in the study, treated with IVIG. Pregnancy outcomes included 17 deliveries and 4 abortions. Two patients were not followed up. The success rate was 81.0% (17/21). But among 4 patients who miscarried, 2 patients were resulted as abnormal pregnancies (chromosomal abnormality & partial hydatdiform mole, respectively), and treated with immunoglobulin during their next pregnancy and gave birth successfully. Therefore, the overall success rate was 89.5% (17/19). 2. Seven out of 17 babies were born vaginally (41.2%), while ten (58.8%) were delivered by cesarean section. Fifteen were born at term, while 2 (11.8%) were preterm (36th and 37th gestatonal weeks, respectively). 3. Twenty-three cases received IVIG once, 21 cases twice and 11 cases three times. The rate of BEI in patients who were not treated with IVIG was -3.23±31.42% (N=23)(range: -53.6∼75%). The rate of seroconversion of BEI in patients who were treated with IVIG was 21.81±30.31% (N=20)(range: -42.2∼75%). The converted BEI rate after second infusion of IVIG was 14.34±14.24 (N=5)(range: -10∼26.5%) in 5 out of in 20 patients who showed poor results and needed a recheck. There was no adverse effect of IVIG. Immunotherapy with human IVIG is effective in unexplained recurrent spontaneous abortion and the rate of seroconversion of BEI was increased. However, the immunomodulating effect of IVIG`s related to its possible mechanism to prevent abortion remains unestablished.

e-비즈니스 시스템에 SOA를 도입하기 위한 방법

황윤영,이규철 충남대학교 산업기술연구소 2006 산업기술연구논문집 Vol.21 No.1

다양하고 많은 e-비즈니스 프레임워크의 등장으로 인해, 기업에서는 모든 프레임워크를 수용해야 하는 부담을 갖게 되었다. 기업의 부담을 최소화하기 위해서는 프레임워크들 간의 연계를 위한 서비스가 필요 한데, 가장 대표적인 기술로는 SOA가 있다. 그러나 e-비즈니스 시스템에 SOA를 도입하기 위해서는 체계적이며, 표준화된 도입 지침이 필요하다. 이를 위해서, 본 논문에서는 SOA의 생명주기 단계에 맞추어 현재 e-비즈니스 시스템 및 관계자가 수행해야 하는 역할 및 목표 등을 제시 한다. 또한, 각 단계 결과물과 참여하는 사람 및 기관의 역할을 제안하고, 각 단계에서의 SOA 적용 방안과 필수 사항을 제안한다. This study is to provide the guideline of SOA adoption for e-business systems. The guideline helps the effective and hierarchical adoption of SOA to e-business systems. So, according to the SOA life-cycle, we describe the purpose of a current system and the action of a related actors. Also, we describe the artifacts at the result in the each stage, and what the actors related to the stage do.

간호대학생의 학업 스트레스 대처 유형

황윤영,이은숙 한국주관성연구학회 2018 주관성연구 Vol.- No.43

The purpose of this study was to identify coping styles toward academic stress in nursing students using Q-methodology. The 42 selected Q-statements from each of 30 participants were classified into the shape of normal distribution using a 9-point scale. The collected data were analyzed using the pc-QUANL program. The results revealed four types of nursing students coping styles toward academic stress: Type Ⅰ is Avoidant projection, type Ⅱ is Positive activity seeking, type Ⅲ is Goal-oriented patience, and type Ⅳ is ordinary means application. The findings can be used as a basis for the design of a differentiated academic stress education according to each type of coping styles. This calls for diverse research on academic stress and the implementation of effective academic stress education. 본 연구는 Q 방법론을 적용해 간호대학생의 학업 스트레스 대처 유형과 유형별 특성을 파악함으로써, 학업 스트레스 대처 교육 프로그램 개발 등에 기초자료를 제공하고자 하였다. 이를 위해 42개의 Q 표본을 확정하고 간호대학생 30명을 P 표본으로 편의표집한 후, 42개의 Q 표본을 9점 척도의 Q 분포도상에 강제 분포하도록 하였다. 수집된 자료는 PC-QUANL 프로그램에 의한 주인자분석법으로 처리하였다. 연구 결과, 간호대학생의 학업스트레스 대처 유형은 회피적 투사형, 적극적 활동 추구형, 목표지향적 인내형 및 일상적 수단 활용형의 4개 유형으로 분류되었다. 이상을 통해, 간호대학생이 학업 스트레스를 효과적으로 관리할 수 있도록 지원하기 위하여각 유형별 특성을 반영한 교육 및 상담 프로그램의 개발과 적용이 이루어져야 할 것이다.

문제중심학습법으로 학습한 간호학생의 메타인지, 비판적 사고력, 자기효능감간의 관계

황윤영,박창승,주민선 지역사회간호학회 2007 지역사회간호학회지 Vol.18 No.1

Correlations among Meta Cognition, Critical Thinking and Self-efficacy of Nursing Students Studying through Problem Based Learning(PBL) Hwang, Yoon-Young․.Park, Chang-Seung Chu, Min-Sun Purpose: This study was performed to examine the degree of meta cognition, critical thinking and self-efficacy and to identify correlations among the meta cognition, critical thinking, and self-efficacy of nursing students studying through PBL. Method: The subjects were 140 nursing students who had studied through PBL over three terms at C College. Data were collected from August to September, 2005 using a structured questionnaire and analyzed using SPSS 10.0. Results: The mean score of meta cognition was 40.14 (SD=6.02), critical thinking was 181.46 (SD=14.49), and self-efficacy was 942.93 (SD=167.05). There was a statistically significant positive correlation between meta cognition and self-efficacy and age. Also, meta cognition had a positive correlation with appropriateness to nursing and interest in nursing knowledge, and critical thinking had a positive correlation with appropriateness to nursing, interest in nursing knowledge, interest in lab on campus and interest in clinical practicum. There were statistically significant positive correlations among meta cognition, critical thinking and self-efficacy. Conclusion: Based on above results, further research should be done about many factors influencing nursing students' problem solving abilities for the development and application of many teaching methods for improving nursing students' meta cognition, critical thinking and self-efficacy.