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      • KCI등재

        시라카바파(白樺派)의 서양미술 수용과정 -『시라카바(白樺)』와 「니카회(二科会)」를 중심으로-

        문형자(文亨子) 한국일본문화학회 2020 日本文化學報 Vol.0 No.86

        This study examines the effects of the Shirakaba school’s acceptance of Western art with a focus on the “Shirakaba” and "Nika" groups. Since the Meiji period, Japan has implemented a national policy aimed at catching up with Western advancements and there has been a movement to reflect this trend in the art field. In the early Meiji period, the promotion of art grew under the protection of the government as part of national policy. The Meiji government established an art school and a government-sponsored exhibition to implement policies. However, there has been a series of abuse aimed at exhibition judges, undermining their authority and the nature of the policy that tried to bring advanced art into the system. Seiki Kuroda, a teacher at the Tokyo art school and then head of the Hakuba society attempted to overcome this situation. Shirakaba school formed the Nika group, insisting on seeing anti-academy and anti-exhibition participation. In the end, the Shirakaba school and Shirakaba magazine served as spearheads to promote Western art in Japan in the course of Japan’s modern westernization as well as stepping stones to nurture students after school. Meanwhile, as Kojima Kikuo and Hosokawa Moritatsu who were involved in the Shirakaba school had a certain status in the Western art troupe of Japan, intervened in the production of the portrait of Yasui Sotaro. Finally, the Shirakaba school has led to excessive interference in the creative activities of their successors.

      • KCI등재

        혈우병 A 진단을 위한 한국인의 St14.1 (DXS52) / TaqI RFLPs 에 대한 분자 유전학적 연구

        문형,정성노,이춘근,백용균,류명수,조율희,신정환 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.11

        서로 혈연관계가 없는 정상 남녀 99명(남자 48명, 여자 51명)으로부터 얻어진 150개의 X염색체에 대한 St14.1(DXS52)/TaqI RFLPs 분석에서 다음과 같은 결과를 얻었다. 1. St14.1 탐침과 제한효소 TaqI에 의해서 5.2kb에서 3,4kb까지 다양한 크기의 대립인자를 갖는 다대립인자계(multiallelic system)와 α(5.5kb), β(1.4kb)로 구분되는 쌍대립인자계(biallelic system)를 나타냈다. 2. 다대립인자계에서는 1번을 제외한, 2∼8번까지 7개의 대립인자가 모두 관찰되었으며 이중 7번 (27.3%), 8번(41.3%) 대립인자의 빈도가 두드러지게 높았다. 3. 쌍대립인자계에서의 α,β대립인자빈도는 각각 54%와46%였다. 4. 한국인 여성 51명에 대한 이형접합체 빈도는 다대립인자계가 71%, 쌍대립인자계에서는 45%로 나타났으며, 두 대립인자계중 한쪽에서라도 이형접합체를 나타낸 빈도는 80%였다. 본 연구결과 St14.1탐침은 이형접합체 빈도로 부터 산출된 다양성정보제공율이 80%로 나타나 타인종에서와 같이 한국인 혈우병 A의 보인자검출 및 산전진단에도 대단히 유용하게 적용될 수 있을 것으로 사료된다. One hundred and fifty unrelated normal X chromosomes (48 males and 51 females) were studied to determine the frequency of alleles for the St14.1(DXS52)/TaqI restriction fragment length polymorphisms associated with FVIII: C gene in Korean population. Using St14.1 probe and restriction enzyme TaqI, two indepenent systems of alleles, multiallelic (1 to 8 alleles) and biallelic (αandβalleles) systems were detectable. Compared with Caucasians, the multiallelic system has demonstrated 7 alleles (2 to 8) except allele 1 and the frequency of alleles 7 and 8 were predominant in Koreans, which is similar to that reported in Chinese. The frequency of αandβ alleles in the biallelic system were 54% and 46%, respectively. The female heterozygote rate for multiallelic system and biallelic system were 71%(36/51) and 45%(23/51), respectively. 80%(41/51) of the Korean females evaluated were heterozygote for one or both system of alleles. The above results indicate that the probe St14.1 is very informative and can be used effectively for prenatal diagnosis and carrier detection of Hemophilia A in Korean population as in other ethnic groups.

      • KCI등재

        임신중 감작된 Rh음성 임부의 치험 1 예

        문형,박문일,정성노,정창영,임기은,오명석,김기성 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.12

        본원 산부인과에서는 최근 Rh 음성 임부가 간접 Coombs검사상 항체역가가 증가하여 양수천자에 의한 분광비색검사후 임신 제 33주에 조기분만을 유도한 1예를 경험하였기에 간단한 문헌고찰과 함께 보고하였다. When the Rh negative mother is sensitized, the risk of erythroblastosis fetalis is increased. If the indirect Coombs test titer is at or above the level of 1: 16 and an amniotic fluid ^450 falls into the 80%-90% level of zone 2 or into zone 3, prompt delivery should be undertaken or intrauterine transfusion is considered. We experienced a case of successful delivery in a sensitized Rh negative mother who was monitored using indirect Coombs test and amnoitic fluid spectrophotometry. We present this case with a brief review of literatures.

      • KCI등재
      • SCOPUSKCI등재
      • KCI등재

        혈우병 A가족에 대한 분자유전학적 연구

        문형,고재경,정성노,이춘근,이노범,유명수,김창열,이항,김용석 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.7

        본 연구는 혈우병 A가 있는 9가족의 20예와 정상여자 9예로부터 채취한 서로 무관한 39개의 X염색체에 대하여 대립인자의 빈도와 다양성 정보제공율을 알아보았고 혈우병 9가족중 몇 가족이 탐침 DX13에 의하여 보인자 색출에 또는 차기임신시 태아의 유전병진단에 도움을 줄 수 있는지를 알아보았다. 1.제한효소 Bg1 II와 탐침 DX13에 의하여 나타난 대립인자는 5.8kb와 2.8kb였다. 2. 대립인자 A1과 A2의 발현빈도는 각각 36%(14/39)와 64%(25/39)였다. 3. 혈우병 가족중 44.4%(4/9)가 RFLP를 보여 딸의 보인자 또는 태아 유전병진단에 도움을 줄 수 있었다. 4. 다양성 정보제공율은 0.46이었다. 본 연구 결과 탐침 DX13은 혈우병 가족들중 약반에서 정보를 제공할 수 있었으므로 국내의 보인자 색출 및 태아 유전병진단에 유용한 탐침이 될 것으로 사료된다. Blood specimens from 20 cases of hemophilia A familes and 9 normal women were obtained to determine the frequency of restricion fragment length polymorphisms associated with the factor Ⅷ; C gene by probe DX13. The minimum number of the independent alleles was at least 39. 1. The two fragments were identified by probe DX13. The A1 allele showed the 5.8Kb fragment and the A2 allele the 9Kb fragment. 2.Of the nine families tested, four(44.4%) were found to be informative because the RFLPs were shown and the remaining five(55.6%) uninformative. 3. The frequencies of A1 and A2 allele were 36%(14/39) and 64%(25/39), respectively. 4. Polymorphism information content was 0.46. The above results indicate that restriction enzyme analysis with prove DX13 is very informative and could be utilized for carrier detection and prenatal diagnosis of hemophilia A in Korean population.

      • KCI등재

        자궁근층내로 감입된 대망 1 례

        문형,유중배,나도수,김진조,박영준 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.6

        인공유산에 의해 발생한 자궁천공과 그에 따른 대망의 자궁근층내로의 감입된 예는 저자들이 고찰한 문헌상 본 증례가 처음으로 사료되어 본 증례를 문헌 고찰과 함께 보고하는 바이다. A case of described where omentum impacted and fenestrated through the anteior uterine wall after induced abortion at the private clinic. The patient had been aborted six times in the past, involving the two recently. And it is postulated that the uterus had been perforated on one of these occasions. We experienced one case of omental impaction in the uterine myometrium after induced abortion and so we present it with brief review of literature.

      • SCIESCOPUSKCI등재

        부인암 환자의 항암화학요법시 발생된 백혈구 감소증에 대한 Granulocyte-Colony Stimulating Factor의 임상 효과

        문형,노재숙,조삼현,황윤영,이재억,김경태 대한부인종양 콜포스코피학회 1994 Journal of Gynecologic Oncology Vol.5 No.1

        The recent introduction of chemotherapy in the treatment of gynecological malignancies has gained wide acceptance along with prstoperative and prostperative adjuvant therapy and with preradiation and concurrent chemoradiation therapy. But, the side effects of chemotherapy including bleeding and infection due to, bone marrow suppression have reaulted in delayed treatment and a reduction in the chemotherspeutic agent used. Recent efforts overcome this bone marrow suppression have led to development of the various human colony-stimulating factor indluding recombinant granulocyte colony-stimulating factor. The author investigated the clinical benefita and toxicity of G-CSF used during chemotherapy of various gynecological malignancies at the Departent of Obstetrics & Gynecology at Hanyang University between August, 1991 and July, 1992. The results were as follows ; 1. An increase in the number of neutrophils follwings a single injection of G-CSF was noted in 19 out of 21 cases(600~1,000/㎣ before injection, 4,500!12,000/㎣ after injection). The remaining 2 cases showed an increase after3~5 continuous injections. 2. To assess the increase in neutropjils according to the dosage of G-CSF given, 100 and 300㎍/㎡ of G-CSF were injected in each trial of chemotherapy in a single case of ovarian cancer. The results were a 1.5 time increase when injected when injected with 300㎍/㎡ 3. After injecting into a patient with recurrent endometrial cancer who was managed with 15gm of ifosfamide, 50gm of cis-platimun, 50gm of adriamycin and 3gm of mesna following surgery, no evidence of neutropenia could be found after 4days of prophylactic G-CSF injections. 4. Patients with cervix cancer with metastasis to the lung were first treated with GM-CSF in one trial and G-CSF in the nest. Patients treated with GM-CSF for a period of 7 days showed leukocytosis(3,600./㎣) but the number was reduced to 1,400/㎣ after 7 days. On the other hand, patients treated with G-CSF showed an increase of 5,700/㎣ within one day and this figure did not dicrease until 20 days later. 5. The toxic effects of G-CSF inclued one case of severe back pain was esily managed by administration acetaminophen. Ohters were headache, chills, general weakness and redness of the oral mucosa and injection area. Most of the theses symptoms disappeared within 2 days. the G-CSF is effective in neutropenia during chemotherapy thereby decreasing the incidence of treatment delay or dose reduction. It also increases the amount of chemotherapeutic agent administered and its toxicity is more tolerable making a rigid systemic chemotherapeutic regime possible

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