Phospholipid 중간체의 효과적인 합성에 관한 연구

장기석 空軍士官學校 1992 論文集 Vol.31 No.-

The key staring materal for the synthesis of the title compound is L-aspartic acid. The title compound was obtailed through diesterification of L-aspartic acid, acylation, chemospecific reduction, regioselective protection(tritylation), condensation, deprotection and halogenation.

Gel Polymer Electrolyte of Lithium Ion Battery Research Using via Ultraviolet Curing

장기석,윤수진,Wei Zhang,임현민,배완수,전민혁,박성준,장호현,김환기 한국고분자학회 2022 한국고분자학회 학술대회 연구논문 초록집 Vol.47 No.1

뇌척수액 세포검사를 통해 발견된 원발성 아교모세포종증 -증례 보고-

장기석,장시형,송영수,박문향,Jang, Ki-Seok,Jang, Si-Hyong,Song, Young-Soo,Park, Moon-Hyang The Korean Society for Cytopathology 2005 대한세포병리학회지 Vol.16 No.2

Primary leptomeningeal glioblastomatosis is a rare and fatal tumor of the central nervous system, the condition is characterized by diffuse infiltration of the tumor in the meninges without evidence of primary tumor within the brain or spinal cord. We reported an unusual case of leptomengial glioblastomatosis, which was detected by the consecutive cerebrospinal fluid (CSF) cytology with application of immunohistochemistry, in addition to its cytologic findings. A healthy 21 year old man, who was enlisted in the army, presented with a stuporous mental state and diffuse enhancement of meninges without evidence of primary mass lesion in the brain and spinal cord on magnetic resonance imaging(MRI). CSF cytology showed small loose clusters of tumor cells with single cells and lymphocytes. The tumor showed variable pleomorphism with coarse chromatin, irregular nuclear membranes and multi lobated nuclei. On immunohistochemical staining, the tumor cells were founded to be positive for GFAP. In conjunction with radiologic findings, brain biopsy confirmed the diagnosis of leptomenigeal glioblastomatosis. The use of immunohistochemistry is helpful in confirming CSF cytologic diagnosis in patients with primary leptomeningeal glioblastomatosis.

Sarcomatoid Carcinoma of the Distal Common Bile Duct - A Case Report -

장기석,장시형,오영하,최호순,이경근,최동호,백승삼 대한병리학회 2005 Journal of Pathology and Translational Medicine Vol.39 No.5

Sarcomatoid carcinoma of the common bile duct (CBD) is an extremely rare malignant neoplasm, which is characterized by the presence of carcinomatous and sarcomatous components. We report a case of sarcomatoid carcinoma arising in the distal CBD. The patient was a 68- year-old woman who presented with abdominal pain. The computed tomography and endoscopic ultrasonography revealed a polypoid mass in the distal CBD. The resected specimen showed a polypoid mass with a narrow stalk in the distal CBD which was confined to the mucosa. The cut surface revealed a gray-whitish solid mass with focal hemorrhage and necrosis. Microscopically, the tumor was composed of carcinomatous and sarcomatous components without any heterologous elements. The sarcomatous area predominently consisted of pleomorphic spindle cells. The carcinomatous component was an adenocarcinoma. On immunohistochemistry, cytokeratin was coexpressed in the carcinomatous and sarcomatous components but vimentin was expressed exclusively in the sarcomatous component. The patient has been doing well for one year postoperatively.

Collision of Three Histologically Distinct Endometrial Cancers of the Uterus

장기석,이원무,김영재,조삼현 대한의학회 2012 Journal of Korean medical science Vol.27 No.1

A collision tumor is defined by the presence of two separate masses in one organ, which are pathologically distinct. We described a 70-yr-old patient who complained of abnormal vaginal bleeding with a collision tumor of the uterine corpus. The patient received total hysterectomy, bilateral salphingo-oophorectomy, bilateral pelvic-paraaortic lymphadenectomy, omentectomy, and intraperitoneal chemotherapy. The uterine corpus revealed three separate masses, which were located at the fundus, anterior and posterior wall. Each tumor revealed three pathologically different components, which were malignant mixed müllerian tumor, papillary serous carcinoma, and endometrioid adenocarcinoma. Among these components, only the papillary serous carcinoma component invaded the underlying myometrium and metastasized to the regional lymph node. Adjuvant chemotherapy and radiation therapy were performed. The patient is still alive and has been healthy for the last 8 yr. We have reviewed previously reported cases of collision tumors which have occurred in the uterine corpus.

기업 합병·인수 과정에서 발생하는 범죄에 대한 수사

장기석,김범식 한국비교형사법학회 2013 비교형사법연구 Vol.15 No.2

Mergers and acquisitions (abbreviated M&A) are both an aspect of corporate strategy, corporate finance and management dealing with the buying, selling, dividing and combining of different companies and similar entities that can help an enterprise grow rapidly in its sector or location of origin, or a new field or new location, without creating a subsidiary, other child entity or using a joint venture. Terms of M&A in Republic of Korea law are Restriction on Combination of Enterprises in ‘Monopoly regulations and fair trade law’ or Written Agreement of Merger, Written Agreement of Consolidation and Division and Merger through Division of Company in Commercial Act. M&A cause positive effects on the corporate development, increase the corporate´s competitiveness, expand into new fields and more. However, M&A also cause negative effects, such as deepen monopoly structure and expend speculation tendency. This study explored the concept and form of the M&A in Republic of Korea society and the occurrent crime during the M&A. This study suggest improvement plan on Investigation based on these crimes caused by the M&A.

ZnS/CdS 분말과 박막의 구조 및 광학적 특성

장기석,Chang, Ki-Seog 한국군사과학기술학회 2010 한국군사과학기술학회지 Vol.13 No.4

The ZnS/CdS thin films were made using 99.99% ZnS and CdS(Aldrich) powders in $7{\times}10^{-6}torr$. The ZnS layer was coated over the CdS layer on an AlOx membrane within a vacuum, at the average speed of $1{\AA}/sec$. After studying the ZnS/CdS and CdS thin films(both with the dimensions of 2.52nm), using fluorescence spectroscopy and comparing the respective results together, we found that although both of the resulting spectra peaked at 390nm, the ZnS/CdS thin films showed a narrower peak, and a higher intensity of photoluminescence than the CdS thin films. The particles of ZnS/CdS thin films also proved to be more homogeneous in size. In addition, the ZnS layer acted as a protective layer. Also, after studying the spectra of ZnS/CdS thin films taken 30 days after their preparation, we found no signs of aging. These results were verified through the scanning electron microscopy(SEM), EDX analysis, thin film X-ray diffraction, and luminescence spectroscopy.

여러 영화들의 표정

장기석 한국독립영화협회 1999 독립영화 Vol.1 No.-

늑막삼출액에서 전이성 샘암종과 유사한 복합 상피성 혈관내피종 - 세포학적 및 면역세포화학적 소견 -

장기석,한홍수,박문향,Jang, Ki-Seok,Han, Hong-Xiu,Park, Moon-Hyang 대한세포병리학회 2003 대한세포병리학회지 Vol.14 No.1

Epithelioid hemangioendothelioma is a rare vascular tumor of borderline malignancy which is characterized by the presence of "epithelioid" or "histiocytoid" endothelial cells. Superficial and deep tumors have been recognized in the extremities, head, neck, chest, and mediastinum of adult patients. It may also occur as a primary tumor of liver, bone, and other visceral organs. Few effusion cytologic findings of epithelioid hemangioendothelioma have been reported. We report a case of composite epithelioid hemangioendothelioma with focal epithelioid angiosarcomatous areas of the iliac bone and adjacent soft tissue in a 38-year-old female, which, during its metastatic course, was presented as a pleural effusion. The effusion was cellular with epithelioid cells presenting both singly and in clusters. The tumor cells were round to ovoid shewing cytoplasmic vacuolization, variability in cell size, and prominent nucleoli. The effusion smears and cell block sections revealed strong positive staining for CD31 and vimentin, weak positive for CD34 and Factor VIII-related antigen, and negative for cytokeratin, CEA, and calretinin. The cytologic findings in this case were similar to that of metastatic adenocarcinoma or malignant mesothelioma. Therefore, immunocytochemical staining in smear and cell block is a helpful tool to differentiate malignant 'epithelioid' cells in effusion.

$SrA1_2(BO_3)_2O$ 화합물에 있어서 열적 수축성 연구

장기석,이영건,오원균,한범수,더글라스케슬러 한국결정학회 2003 韓國結晶學會誌 Vol.14 No.1

화합물, SrAl₂(BO₃)₂O는 매우 효과적으로 열적 수축성을 나타내는 격자를 가지고 있다. 우리는 세라믹 시험편의 열팽창 계수측정법과 X-선 회절 분광법을 이용하여 제한된 온도 범위에서 열적 수축을 각각 측정하였다. 알루미늄 보레이트 화합물에 있어서, 열적 수축성은 23∼215℃ 온도 범위에서 c 축에 대한 열팽창 계수 -1.64×10/sup -4/ Å/℃를 보였으며, 20㎜ 세라믹 시험편에 대한 길이의 변화측정 결과는 110∼170℃ 온도 범위에서 최대 -1.75㎛까지 수축하였다. The compound SrA1₂(BO₃)₂O is a good host lattice for negative thermal expansion. We have measured thermal expansion over the limited temperature range by X-ray diffraction and ceramic dilatometry. In the aluminum borate compound, a thermal contraction is observed with a coefficient -1.64×10/sup -4/ Å/℃ on the c axis in the temperature range 23∼215℃ and with a maximum change -1.75㎛ in length of a ceramic bar of 20㎜ in the temperature range 110∼170℃, respectively.